Selective Loss of Sphingosine 1-Phosphate Signaling with No Obvious Phenotypic Abnormality in Mice Lacking Its G Protein-coupled Receptor, LP B3/EDG-3

Journal of Biological Chemistry

Volumn 276, Issue 36, 2001, Pages 33697-33704

  Ishii, Isao ^a   Friedman, Beth ^a   Ye, Xiaoqin ^a   Kawamura, Shuji ^a   McGiffert, Christine ^b   Contos, James J A ^a   Kingsbury, Marcy A ^a   Zhang, Guangfa ^a   Brown, Joan Heller ^a,b   Chun, Jerold ^a,b,c  

^a San Diego   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; PHOSPHATES; PROTEINS;

PROTEIN-COUPLED RECEPTORS;

BIOCHEMISTRY;

ADENYLATE CYCLASE; G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHATIDIC ACID; PHOSPHOLIPASE C; RHO FACTOR; SPHINGOSINE 1 PHOSPHATE; CYCLIC AMP; DNA BINDING PROTEIN; DRUG DERIVATIVE; I KAPPA B; INOSITOL PHOSPHATE; LYSOPHOSPHOLIPID; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; EMBRYO DEVELOPMENT; ENZYME INHIBITION; FIBROBLAST; GENE DISRUPTION; GENE EXPRESSION REGULATION; HETEROZYGOSITY LOSS; MOUSE; NONHUMAN; PHENOTYPIC VARIATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FAMILY; RECEPTOR GENE; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; ALLELE; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; DOSE RESPONSE; DRUG ANTAGONISM; ENZYME ACTIVATION; GENE DELETION; GENE LIBRARY; GENETICS; IN SITU HYBRIDIZATION; METABOLISM; MOUSE MUTANT; MUTATION; NORTHERN BLOTTING; PHENOTYPE; PHYSIOLOGY; TISSUE DISTRIBUTION; WESTERN BLOTTING;

ANIMALIA; MAMMALIA; UNIDENTIFIED RETROVIRUS;

ADENYLATE CYCLASE; ALLELES; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CYCLIC AMP; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FIBROBLASTS; GENE DELETION; GENE LIBRARY; I-KAPPA B PROTEINS; IN SITU HYBRIDIZATION; INOSITOL PHOSPHATES; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, GENETIC; MUTATION; PHENOTYPE; PHOSPHOLIPASE C; RAC GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SPHINGOSINE; TISSUE DISTRIBUTION;

EID: 0035823477     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104441200     Document Type: Article

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