Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor: Requirement of inhibition of cellular Rac activity

Journal of Biological Chemistry

Volumn 278, Issue 35, 2003, Pages 32841-32851

  Arikawa, Kayo ^a   Takuwa, Noriko ^a   Yamaguchi, Hironori ^b   Sugimoto, Naotoshi ^a   Kitayama, Joji ^b   Nagawa, Hirokazu ^b   Takehara, Kazuhiko ^a   Takuwa, Yoh ^a  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; PROTEINS; SENSITIVITY ANALYSIS;

TOXIN PRETREATMENT;

BIOCHEMISTRY;

CELL RECEPTOR; G PROTEIN COUPLED RECEPTOR; JTE 013; RAC PROTEIN; RECEPTOR BLOCKING AGENT; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECOND MESSENGER;

ADENOVIRIDAE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CALCIUM; CELL MOVEMENT; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENETIC VECTORS; GUANOSINE TRIPHOSPHATE; HETEROTRIMERIC GTP-BINDING PROTEINS; LIGANDS; LYSOPHOSPHOLIPIDS; MELANOMA, EXPERIMENTAL; MICE; NEOPLASM INVASIVENESS; PHOSPHORYLCHOLINE; PLASMIDS; PROTEIN ISOFORMS; PYRAZOLES; PYRIDINES; RAC GTP-BINDING PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SPHINGOSINE; TEMPERATURE; TIME FACTORS;

ADENOVIRIDAE;

EID: 0042858413     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305024200     Document Type: Article

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