Senescent endothelial dysfunction is attributed to the up-regulation of sphingosine-1-phosphate receptor-2 in aged rats

Molecular and Cellular Biochemistry

Volumn 363, Issue 1-2, 2012, Pages 217-224

  Lu, Hongwei ^a   Yuan, Hong ^a   Chen, Shuhua ^b   Huang, Lihua ^a   Xiang, Hong ^a   Yang, Guoping ^a   Deng, Hao ^a   Zhou, Jun ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Central South University   (China)

Author keywords

Aged; Endothelial cells; Rat; Sphingosine 1 phosphate; Sphingosine 1 phosphate receptor 2

Indexed keywords

SHORT HAIRPIN RNA; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; SPHINGOSINE 1 PHOSPHATE RECEPTOR 3; UNCLASSIFIED DRUG;

ADOLESCENT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; GENE SILENCING; GROUPS BY AGE; LUNG BLOOD VESSEL; MALE; MICROVASCULAR ENDOTHELIAL CELL; MONOLAYER CULTURE; MORPHOGENESIS; NONHUMAN; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SENESCENCE; WOUND HEALING IMPAIRMENT;

AGE FACTORS; AGING; ANIMALS; BLOTTING, WESTERN; CELL AGING; CELL SHAPE; CELLS, CULTURED; CHEMOTAXIS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; LUNG; LYSOPHOSPHOLIPIDS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, LYSOSPHINGOLIPID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPHINGOSINE; UP-REGULATION; WOUND HEALING;

RATTUS;

EID: 84857899576     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1173-y     Document Type: Article

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