Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 30, Issue 9, 2010, Pages 1779-1786

  Medlin, Matt D ^a   Staus, Dean P ^a   Dubash, Adi D ^b   Taylor, Joan M ^a   MacK, Christopher P ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

G proteins; gene expression; LARG; lipids; S1P; S1PR2

Indexed keywords

ALPHA ACTIN; CALPONIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LEUKEMIA ASSOCIATED RHOGEF; MITOGEN ACTIVATED PROTEIN KINASE; MYOCARDIN RELATED TRANSCRIPTION FACTOR A; PROTEIN C FOS; PROTEIN PDZ RHOGEF; PROTEIN RHOGEF; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; TUBULIN; UNCLASSIFIED DRUG; ARHGEF12 PROTEIN, MOUSE; LYSOPHOSPHOLIPID; MESSENGER RNA; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHOA PROTEIN, MOUSE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE-1-PHOSPHATE RECEPTOR-2, MOUSE;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CELL MOTION; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; RNA INTERFERENCE; TIME;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL MOVEMENT; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GUANINE NUCLEOTIDE EXCHANGE FACTORS; LYSOPHOSPHOLIPIDS; MICE; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; RECEPTORS, LYSOSPHINGOLIPID; RHO GTP-BINDING PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPHINGOSINE; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS;

EID: 77955985369     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.209395     Document Type: Article

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