Sphingosine-1-phospate receptor 4 (S1P 4) deficiency profoundly affects dendritic cell function and T H17-cell differentiation in a murine model

FASEB Journal

Volumn 25, Issue 11, 2011, Pages 4024-4036

  Schulze, Tobias ^a,c   Golfier, Sven ^a,d   Tabeling, Christoph ^b   Rab̈el, Katrin ^a   Gräler, Markus H ^a,b   Witzenrath, Martin ^b   Lipp, Martin ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UNIVERSITY MEDICINE GREIFSWALD   (Germany)

^d BAYER PHARMA AG   (Germany)

Author keywords

Animal model; G protein coupled receptor; T cell polarization

Indexed keywords

ACETONE; CYTOKINE; DEXTRAN SULFATE; FLUORESCEIN ISOTHIOCYANATE; G PROTEIN COUPLED RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; OVALBUMIN; PHTHALIC ACID DIBUTYL ESTER; SPHINGOSINE 1 PHOSPHATE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL MIGRATION; COCULTURE; COLITIS; CONTACT ALLERGY; CONTROLLED STUDY; CYTOKINE RELEASE; DELAYED HYPERSENSITIVITY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTER; IMMUNE RESPONSE; IN VITRO STUDY; LYMPHOCYTE CULTURE; LYMPHOCYTE HOMING; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; SENSITIZATION; TH1 CELL; TH17 CELL; TH2 CELL;

ANIMALS; CELL DIFFERENTIATION; COLITIS; DENDRITIC CELLS; DEXTRAN SULFATE; IMMUNOGLOBULINS; LYSOPHOSPHOLIPIDS; MICE; MICE, KNOCKOUT; RECEPTORS, LYSOSPHINGOLIPID; SIGNAL TRANSDUCTION; SPHINGOSINE; TH17 CELLS; TH2 CELLS;

ANIMALIA; MURINAE; MUS;

EID: 80355129639     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-179028     Document Type: Article

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