Sphingosine kinase 1 and sphingosine 1-phosphate receptor 3 are functionally upregulated on astrocytes under pro-inflammatory conditions

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Fischer, Iris ^a   Alliod, Chantal ^a   Martinier, Nicolas ^a   Newcombe, Jia ^b   Brana, Corinne ^a   Pouly, Sandrine ^a  

^a MERCK SERONO S A   (Switzerland)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 3; SPHINGOSINE KINASE 1; UNCLASSIFIED DRUG; CXCL1 PROTEIN, HUMAN; PHOSPHOTRANSFERASE; SPHINGOSINE KINASE;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN TISSUE; INFLAMMATION; MACROPHAGE; MULTIPLE SCLEROSIS; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; DRUG EFFECT; METABOLISM; PATHOLOGY; PHYSIOLOGY;

RATTUS;

ANIMALS; ASTROCYTES; CHEMOKINE CXCL1; INFLAMMATION; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MULTIPLE SCLEROSIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RATS; RECEPTORS, LYSOSPHINGOLIPID; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 80051991367     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023905     Document Type: Article

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