Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells

FASEB Journal

Volumn 16, Issue 14, 2002, Pages 1874-1878

  Graeler, Markus ^a   Goetzl, Edward J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chemokine; G protein; Immunity; Lysophospholipid; Receptor

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE; G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHOLIPID; MATRIGEL; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; SPHINGOSINE 1 PHOSPHATE RECEPTOR 3; SPHINGOSINE 1 PHOSPHATE RECEPTOR 4; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SURVIVAL; CHEMOTAXIS; COMPETITIVE INHIBITION; CONTROLLED STUDY; EFFECTOR CELL; GENE ACTIVATION; GENE EXPRESSION REGULATION; IMMUNOREGULATION; LYMPHOCYTE ACTIVATION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SPLEEN LYMPHOCYTE; T LYMPHOCYTE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; FEMALE; GENE EXPRESSION REGULATION; LYMPHOCYTE ACTIVATION; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHOLIPID; RNA, MESSENGER; SPHINGOSINE; SPLEEN; T-LYMPHOCYTES;

ANIMALIA; MAMMALIA;

EID: 0036905055     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.02-0548com     Document Type: Article

References (14)

1. Spiegel, S., and Milstien, S. (1995) Sphingolipid metabolites: Members of a new class of lipid second messengers. J. Membr. Biol. 146, 225-237
2. Moolenaar, W. H., Kranenburg, O., Postma, F. R., and Zondag, G. C. (1997) Lysophosphatidic acid: C-protein signalling and cellular responses. Curr. Opin. Cell Biol. 9, 168-173
3. Gaits, F., Fourcade, O., Le Balie, F., Gaeguen, G., Gaige, B., Gassama-Diagne, A., Fauvel, J., Salles, J. P., Mauco, G., Simon, M. F., and Chap, H. (1997) Lysophosphatidic acid as a phospholipid mediator: Pathways of synthesis. FEBS Lett. 410, 54-58
4. Hla, T., and Maciag, T. (1990) An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors. J. Biol. Chem. 265, 9308-9313
5. Goetzl, E. J., and An, S. (1998) Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J. 12, 1589-1598
6. Chun, J., Contos, J. J., and Munroe, D. (1999) A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs). Cell Biochem. Biophys. 30, 213-242
7. Goetzl, E. J., Kong, Y., and Voice, J. K. (2000) Cutting edge: Differential constitutive expression of functional receptors for lysophosphatidic acid by human blood lymphocytes. J. Immunol. 164, 4996-4999
8. Zheng, Y., Voice, J. K., Kong, Y., and Goetzl, E. J. (2000) Altered expression and functional profile of lysophosphatidic acid re-ceptors in mitogen-activated human blood T lymphocytes. FASEB J. 14, 2387-2389
9. Zheng, Y., Kong, Y., and Goetzl, E. J. (2001) Lysophosphatidic acid receptor-selective effects on Jurkat T cell migration through a Matrigel model basement membrane. J. Immunol. 166, 2317-2322
10. Xia, M., Leppert, D., Hauser, S. L., Sreedharan, S. P., Nelson, P.J., Krensky, A. M., and Goetzl, E.J. (1996) Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane. J. Immunol. 156, 160-167
11. Brinkmann, V., Pinschewer, D., Chiba, K., and Feng, L. (2000) FTY720: A novel transplantation drug that modulates lymphocyle traffic rather than activation. Trends Pharmacol. Sci. 21, 49-52
12. Brinkmann, V., Pinschewer, D. D., Feng, L., and Chen, S. (2001) FTY720: Altered lymphocyte traffic results in allograft protection. Transplantation 72, 764-769
13. Mandala, S., Hajdu, R., Bergstrom, J., Quackenbush, E., Xie, J., Milligan, J., Thornton, R., Shei, G. J., Card, D., Keohane, C., Rosenbach, M., Hale, J., Lynch, C. L., Rupprecht, K., Parsons, W., and Rosen, H. (2002) Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 296, 346-349
14. Brinkmann, V., Davis, M. D., Heise, C. E., Albert, R., Conens, S., Hof, R., Bruns, C., Prieschl, E., Baumruker, T., Hiestand, P., Foster, C. A., Zollinger, M., and Lynch, K. R. (2002) The immune modulator, FTY720, targets sphingosine 1-phosphate receptors. J. Biol. Chem. 277, 21453-21457