Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA Repair

Journal of Molecular Biology

Volumn 397, Issue 3, 2010, Pages 647-663

  Das, Debanu ^a,b   Moiani, Davide ^c   Axelrod, Herbert L ^a,b   Miller, Mitchell D ^a,b   McMullan, Daniel ^a,d   Jin, Kevin K ^a,b   Abdubek, Polat ^a,d   Astakhova, Tamara ^a,e   Burra, Prasad ^a,f   Carlton, Dennis ^a,c   Chiu, Hsiu Ju ^a,b   Clayton, Thomas ^a,c   Deller, Marc C ^a,c   Duan, Lian ^a,e   Ernst, Dustin ^a,d   Feuerhelm, Julie ^a,d   Grant, Joanna C ^a,d   Grzechnik, Anna ^a,c   Grzechnik, Slawomir K ^a,e   Han, Gye Won ^a,c   Jaroszewski, Lukasz ^a,e,f   Klock, Heath E ^a,d   Knuth, Mark W ^a,d   Kozbial, Piotr ^a,f   Krishna, S Sri ^a,e,f   Kumar, Abhinav ^a,b   Marciano, David ^a,c   Morse, Andrew T ^a,e   Nigoghossian, Edward ^a,d   Okach, Linda ^a,d   Paulsen, Jessica ^a,d   Reyes, Ron ^a,b   Rife, Christopher L ^a,b   Sefcovic, Natasha ^a,f   Tien, Henry J ^a,c   Trame, Christine B ^a,b   van den Bedem, Henry ^a,b   Weekes, Dana ^a,f   Xu, Qingping ^a,b   Hodgson, Keith O ^a,g   Wooley, John ^a,e   Elsliger, Marc André ^a,c   Deacon, Ashley M ^a,b   Godzik, Adam ^a,e,f   Lesley, Scott A ^a,c,d   Tainer, John A ^c,h   Wilson, Ian A ^a,c   more..

^a Joint Center for Structural Genomics   (United States)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f BURNHAM INSTITUTE   (United States)

^g SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^h LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

crystal structure; DNA repair; Mre11; nuclease; structural genomics

Indexed keywords

DNA; DOUBLE STRANDED DNA; HISTIDINE; MRE11 PROTEIN; SINGLE STRANDED DNA;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA REPAIR; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN STRUCTURE; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS); PYROCOCCUS FURIOSUS; THERMOTOGA MARITIMA;

EID: 77649338640     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.01.049     Document Type: Article

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