The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation

Cell Research

Volumn 22, Issue 2, 2012, Pages 305-320

  Yu, Zhenbao ^a   Vogel, Gillian ^a   Yan, Coulombe ^b   Dubeau, Danielle ^a   Spehalski, Elizabeth ^c   Hébert, Josée ^d,e   Ferguson, David O ^c   Masson, Jean Yves ^b   Richard, Stéphane ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Arginine methylation; ATR; DNA damage signaling; GAR motif; MRE11

Indexed keywords

ATM PROTEIN; ATR PROTEIN, MOUSE; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; DNA BINDING PROTEIN; MRE11A PROTEIN, MOUSE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RAD51 PROTEIN; RAD51 PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL; ARTICLE; CELL CULTURE; CELL CYCLE CHECKPOINT; CHEMISTRY; CHROMOSOMAL INSTABILITY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVATION; GAMMA RADIATION; GENE TARGETING; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN MOTIF; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; ANIMALS; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELLS, CULTURED; CHROMOSOMAL INSTABILITY; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; ENZYME ACTIVATION; GAMMA RAYS; GENE KNOCK-IN TECHNIQUES; MICE; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RAD51 RECOMBINASE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

MUS;

EID: 84856593640     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2011.128     Document Type: Article

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