Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair

Nucleic Acids Research

Volumn 40, Issue 22, 2012, Pages 11435-11449

  Limbo, Oliver ^a   Moiani, Davide ^a   Kertokalio, Aryandi ^b   Wyman, Claire ^b   Tainer, John A ^a,c   Russell, Paul ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 1; DOUBLE STRANDED DNA; MRE11 PROTEIN; NUCLEASE; RAD50 PROTEIN; RAD52 PROTEIN;

ALLELE; ARTICLE; ATAXIA TELANGIECTASIA; CANCER PATIENT; CASE REPORT; CELL LYSATE; CHEMICAL ANALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME STABILITY; GENE; GENE CONTROL; GENE MUTATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MEIOSIS; MRE11 GENE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PYROCOCCUS FURIOSUS; STRUCTURE ANALYSIS; TELOMERE; YEAST;

AMINO ACID SEQUENCE; ANTIGENS, NUCLEAR; ARCHAEAL PROTEINS; ATAXIA TELANGIECTASIA; CELL CYCLE PROTEINS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPLICATION; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASES; HUMANS; MEIOSIS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PROTEIN-SERINE-THREONINE KINASES; PYROCOCCUS FURIOSUS; RAD52 DNA REPAIR AND RECOMBINATION PROTEIN; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; TELOMERE HOMEOSTASIS; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA; PYROCOCCUS FURIOSUS; SCHIZOSACCHAROMYCETACEAE;

EID: 84871192231     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks954     Document Type: Article

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