Alzheimer's disease-associated peptide Aβ42 mobilizes ER Ca2+ via InsP3R-dependent and -independent mechanisms

Frontiers in Molecular Neuroscience

Volumn 6, Issue NOV, 2013, Pages

  Jensen, Laura E ^a   Bultynck, Geert ^b   Luyten, Tomas ^b   Amijee, Hozeefa ^c   Bootman, Martin D ^a,d   Roderick, H Llewelyn ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

^c Senexis Limited   (United Kingdom)

^d OPEN UNIVERSITY   (United Kingdom)

Author keywords

A Oligomers; Alzheimer's disease; Calcium Ca2+; Endoplasmic reticulum ER; Insp3 Receptors InsP3Rs; InsP3 IP3

Indexed keywords

AMYLOID BETA PROTEIN; CALCIUM ION; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; PHOSPHOLIPASE C; RYANODINE RECEPTOR;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; CALCIUM HOMEOSTASIS; CELL CULTURE; CELL DENSITY; CELL PROLIFERATION ASSAY; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MTT ASSAY; NERVE CELL MEMBRANE POTENTIAL; NEUROBLASTOMA; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS;

EID: 84888320149     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2013.00036     Document Type: Article

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