-
1
-
-
0037042299
-
Alzheimer disease
-
Cummings JL, Cole G. Alzheimer disease. Jama. 2002; 287(18):2335.
-
(2002)
Jama
, vol.287
, Issue.18
, pp. 2335
-
-
Cummings, J.L.1
Cole, G.2
-
2
-
-
0000858424
-
Uber einen eigenartigen schweren Krankheitsprozess der Hirnrinde
-
Alzheimer A. Uber einen eigenartigen schweren Krankheitsprozess der Hirnrinde. Zentralblatt fur Nervenkrankheiten. 1906; 25:1134.
-
(1906)
Zentralblatt Fur Nervenkrankheiten
, vol.25
, pp. 1134
-
-
Alzheimer, A.1
-
3
-
-
33645824170
-
Amyloid beta: The alternate hypothesis
-
Lee HG, et al. Amyloid beta: the alternate hypothesis. Curr Alzheimer Res. 2006; 3(1): 75.
-
(2006)
Curr Alzheimer Res.
, vol.3
, Issue.1
, pp. 75
-
-
Lee, H.G.1
-
4
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol. 1956; 11(3):298.
-
(1956)
J Gerontol.
, vol.11
, Issue.3
, pp. 298
-
-
Harman, D.1
-
5
-
-
0017177978
-
Free radical theory of aging: Inhibition of amyloidosis in mice by antioxidants; possible mechanism
-
Harman D, Eddy DE, Noffsinger J. Free radical theory of aging: inhibition of amyloidosis in mice by antioxidants; possible mechanism. J Am Geriatr Soc. 1976; 24(5):203.
-
(1976)
J Am Geriatr Soc.
, vol.24
, Issue.5
, pp. 203
-
-
Harman, D.1
Eddy, D.E.2
Noffsinger, J.3
-
6
-
-
0028946289
-
Radical AGEing in Alzheimer's disease
-
Smith MA, et al. Radical AGEing in Alzheimer's disease. Trends Neurosci. 1995; 18(4):172.
-
(1995)
Trends Neurosci.
, vol.18
, Issue.4
, pp. 172
-
-
Smith, M.A.1
-
7
-
-
18744374615
-
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
-
Perry G, et al. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med. 2002; 33(11):1475.
-
(2002)
Free Radic Biol Med.
, vol.33
, Issue.11
, pp. 1475
-
-
Perry, G.1
-
8
-
-
0032229327
-
Reactive oxygen species mediate cellular damage in Alzheimer disease
-
Perry G, et al. Reactive oxygen species mediate cellular damage in Alzheimer disease. J Alzheimers Dis. 1998; 1(1):45.
-
(1998)
J Alzheimers Dis.
, vol.1
, Issue.1
, pp. 45
-
-
Perry, G.1
-
9
-
-
0035875690
-
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
-
Pratico D, et al. Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J Neurosci. 2001; 21(12):4183.
-
(2001)
J Neurosci.
, vol.21
, Issue.12
, pp. 4183
-
-
Pratico, D.1
-
10
-
-
0030885482
-
Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
-
Smith MA, et al. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci U S A. 1997; 94(18):9866.
-
(1997)
Proc Natl Acad Sci U S A.
, vol.94
, Issue.18
, pp. 9866
-
-
Smith, M.A.1
-
11
-
-
27544484846
-
Are mitochondria critical in the pathogenesis of Alzheimer's disease?
-
Reddy PH, Beal MF. Are mitochondria critical in the pathogenesis of Alzheimer's disease? Brain Res Brain Res Rev. 2005; 49(3):618.
-
(2005)
Brain Res Brain Res Rev.
, vol.49
, Issue.3
, pp. 618
-
-
Reddy, P.H.1
Beal, M.F.2
-
12
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
Mattson MP. Pathways towards and away from Alzheimer's disease. Nature. 2004; 430(7000):631.
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 631
-
-
Mattson, M.P.1
-
13
-
-
33646152108
-
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: Implications for free radical generation and oxidative damage in disease progression
-
Manczak M, et al. Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Hum Mol Genet. 2006; 15(9):1437.
-
(2006)
Hum Mol Genet.
, vol.15
, Issue.9
, pp. 1437
-
-
Manczak, M.1
-
14
-
-
39149122810
-
Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease
-
Reddy PH, Beal MF. Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med. 2008; 14(2):45.
-
(2008)
Trends Mol Med.
, vol.14
, Issue.2
, pp. 45
-
-
Reddy, P.H.1
Beal, M.F.2
-
15
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai K, et al. Mitochondrial abnormalities in Alzheimer's disease. J Neurosci. 2001; 21(9):3017.
-
(2001)
J Neurosci.
, vol.21
, Issue.9
, pp. 3017
-
-
Hirai, K.1
-
16
-
-
0037010312
-
Role of mitochondrial dysfunction in Alzheimer's disease
-
Castellani R, et al. Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res. 2002; 70(3):357.
-
(2002)
J Neurosci Res.
, vol.70
, Issue.3
, pp. 357
-
-
Castellani, R.1
-
17
-
-
0033964859
-
In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: A central role for bound transition metals
-
Sayre LM, et al. In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. J Neurochem. 2000; 74(1):270.
-
(2000)
J Neurochem.
, vol.74
, Issue.1
, pp. 270
-
-
Sayre, L.M.1
-
18
-
-
0032514165
-
Promotion of transition metalinduced reactive oxygen species formation by beta-amyloid
-
Bondy SC, Guo-Ross SX, Truong AT. Promotion of transition metalinduced reactive oxygen species formation by beta-amyloid. Brain Res. 1998; 799(1):91.
-
(1998)
Brain Res.
, vol.799
, Issue.1
, pp. 91
-
-
Bondy, S.C.1
Guo-Ross, S.X.2
Truong, A.T.3
-
19
-
-
18344414746
-
The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
Huang X, et al. The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry. 1999; 38(24):7609.
-
(1999)
Biochemistry
, vol.38
, Issue.24
, pp. 7609
-
-
Huang, X.1
-
20
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
Nunomura A, et al. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci. 1999; 19(6):1959.
-
(1999)
J Neurosci.
, vol.19
, Issue.6
, pp. 1959
-
-
Nunomura, A.1
-
21
-
-
33947178563
-
Alzheimer disease, the two-hit hypothesis: An update
-
Zhu X, et al. Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta. 2007; 1772(4):494.
-
(2007)
Biochim Biophys Acta.
, vol.1772
, Issue.4
, pp. 494
-
-
Zhu, X.1
-
22
-
-
1642358352
-
Alzheimer's disease: The two-hit hypothesis
-
Zhu X, et al. Alzheimer's disease: the two-hit hypothesis. Lancet Neurol. 2004; 3(4):219.
-
(2004)
Lancet Neurol.
, vol.3
, Issue.4
, pp. 219
-
-
Zhu, X.1
-
23
-
-
0034797352
-
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: The 'two hit' hypothesis
-
Zhu X, et al. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mech Ageing Dev. 2001; 123(1):39.
-
(2001)
Mech Ageing Dev.
, vol.123
, Issue.1
, pp. 39
-
-
Zhu, X.1
-
24
-
-
0029899586
-
Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors
-
Bruce AJ, et al. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nat Med. 1996; 2(7):788.
-
(1996)
Nat Med.
, vol.2
, Issue.7
, pp. 788
-
-
Bruce, A.J.1
-
25
-
-
0026343873
-
Alzheimer's and Parkinson's disease. Brain levels of glutathione, glutathione disulfide, and vitamin E
-
Adams JD Jr, et al. Alzheimer's and Parkinson's disease. Brain levels of glutathione, glutathione disulfide, and vitamin E. Mol Chem Neuropathol. 1991; 14(3):213.
-
(1991)
Mol Chem Neuropathol.
, vol.14
, Issue.3
, pp. 213
-
-
Adams Jr., J.D.1
-
26
-
-
0028059308
-
Oxidative damage in neurodegenerative disease
-
Jenner P. Oxidative damage in neurodegenerative disease. Lancet. 1994; 344(8925):796.
-
(1994)
Lancet
, vol.344
, Issue.8925
, pp. 796
-
-
Jenner, P.1
-
27
-
-
0029125266
-
Free radical involvement in neuropsychiatric illnesses
-
Lohr JB, Browning JA. Free radical involvement in neuropsychiatric illnesses. Psychopharmacol Bull. 1995; 31(1):159.
-
(1995)
Psychopharmacol Bull.
, vol.31
, Issue.1
, pp. 159
-
-
Lohr, J.B.1
Browning, J.A.2
-
28
-
-
1442314722
-
Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease
-
Sung S, et al. Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease. Faseb J. 2004; 18(2):323.
-
(2004)
Faseb J.
, vol.18
, Issue.2
, pp. 323
-
-
Sung, S.1
-
29
-
-
0037178579
-
Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study
-
Morris MC, et al. Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA. 2002; 287(24):3230.
-
(2002)
JAMA
, vol.287
, Issue.24
, pp. 3230
-
-
Morris, M.C.1
-
30
-
-
0038115068
-
Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease
-
Morris MC, et al. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol. 2003; 60(7):940.
-
(2003)
Arch Neurol.
, vol.60
, Issue.7
, pp. 940
-
-
Morris, M.C.1
-
31
-
-
0036334166
-
Caloric intake and the risk of Alzheimer disease
-
Luchsinger JA, et al. Caloric intake and the risk of Alzheimer disease. Arch Neurol. 2002; 59(8):1258.
-
(2002)
Arch Neurol.
, vol.59
, Issue.8
, pp. 1258
-
-
Luchsinger, J.A.1
-
32
-
-
35348981740
-
Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide
-
Hayashi T, et al. Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide. Free Radic Biol Med. 2007; 43(11):1552.
-
(2007)
Free Radic Biol Med.
, vol.43
, Issue.11
, pp. 1552
-
-
Hayashi, T.1
-
33
-
-
35948936850
-
Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron
-
Nakamura M, et al. Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron. Biochemistry. 2007; 46(44):12737.
-
(2007)
Biochemistry
, vol.46
, Issue.44
, pp. 12737
-
-
Nakamura, M.1
-
34
-
-
0025726462
-
Intramuscular desferrioxamine in patients with Alzheimer's disease
-
Crapper McLachlan DR, et al. Intramuscular desferrioxamine in patients with Alzheimer's disease. Lancet. 1991; 337(8753):1304.
-
(1991)
Lancet
, vol.337
, Issue.8753
, pp. 1304
-
-
Crapper McLachlan, D.R.1
-
35
-
-
33646855957
-
Neuropathology of Alzheimer disease: Pathognomonic but not pathogenic
-
Castellani RJ, et al. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol (Berl). 2006; 111(6):503.
-
(2006)
Acta Neuropathol (Berl)
, vol.111
, Issue.6
, pp. 503
-
-
Castellani, R.J.1
|