Calcium signals induced by amyloid β peptide and their consequences in neurons and astrocytes in culture

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1742, Issue 1-3, 2004, Pages 81-87

  Abramov, Andrey Y ^a   Canevari, Laura ^b   Duchen, Michael R ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NONE

Author keywords

Alzheimer's disease; Amyloid ; Intracellular calcium; Intracellular pH; NADPH oxidase; Oxidative stress

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[25-35]; ANTIOXIDANT; APOCYNIN; CLIOQUINOL; DIPHENYLIODONIUM SALT; GLUTATHIONE; HYDROGEN; OXIDOREDUCTASE INHIBITOR; PROTON; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ACIDIFICATION; ALZHEIMER DISEASE; ASTROCYTE; BINDING SITE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CLINICAL TRIAL; CONFERENCE PAPER; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; HIPPOCAMPUS; HUMAN; IMMUNOCOMPETENT CELL; ION EXCHANGE; MEMBRANE CHANNEL; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMYLOID BETA-PROTEIN; ANIMALS; ASTROCYTES; CALCIUM SIGNALING; CELLS, CULTURED; HUMANS; HYDROGEN-ION CONCENTRATION; NEURONS; OXIDATIVE STRESS;

EID: 10044244916     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2004.09.006     Document Type: Conference Paper

References (25)

1. P.F. Chapman, G.L. White, M.W. Jones, D. Cooper-Blacketer, V.J. Marshall, M. Irizarry, L. Younkin, M.A. Good, T.V.P. Bliss, B.T. Hyman, S.G. Younkin, and K.K. Hsiao Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice Nat. Neurosci. 2 1999 271 276
2. D.A. Snowdon Aging and Alzheimer's disease: lessons from the Nun Study Gerontologist 37 1997 150 156
3. S.J. Kish Brain energy metabolizing enzymes in Alzheimer's disease: β-ketoglutarate dehydrogenase complex and cytochrome oxidase Ann. N.Y. Acad. Sci. 826 1997 218 228
4. G.E. Gibson, H. Zhang, K.F. Sheu, N. Bogdanovich, J.G. Lindsay, L. Lannfelt, M. Vestling, and R.F. Cowburn α-Ketoglutarate dehydrogenase in Alzheimer brains bearing the APP670/671 mutation Ann. Neurol. 44 1998 676 681
5. c and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity J. Neurosci. 23 2003 5088 5095
6. A.Y. Abramov, L. Canevari, and M.R. Duchen Amyloid β peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase J. Neurosci. 24 2004 565 575
7. N. Arispe, E. Rojas, and H.B. Pollard Alzheimer disease amyloid β protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum Proc. Natl. Acad. Sci. U. S. A. 90 1993 567 571
8. H. Lin, R. Bhatia, and R. Lal Amyloid β protein forms ion channels: implications for Alzheimer's disease pathophysiology FASEB J. 15 2003 2433 2444
9. 2+ interaction with Alzheimer amyloid β-protein calcium channels Proc. Natl. Acad. Sci. U. S. A. 93 1996 1710 1715
10. A.I. Bush The metallobiology of Alzheimer's disease Trends Neurosci. 26 2003 207 214
11. 2+-sensitive channel J. Biol. Chem. 273 1998 13379 13382
12. R.A. Cherny, C.S. Atwood, M.E. Xilinas, D.N. Gray, W.D. Jones, C.A. McLean, K.J. Barnham, I. Volitakis, F.W. Fraser, Y. Kim, X. Huang, L.E. Goldstein, R.D. Moir, J.T. Lim, K. Beyreuther, H. Zheng, R.E. Tanzi, C.L. Masters, and A.I. Bush Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice Neuron 30 2001 665 676
13. N. Arispe, and M. Doh Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease A(P (1-40) and (1-42) peptides FASEB J. 16 2002 1526 1536
14. M. Kawahara, and Y. Kuroda Intracellular calcium changes in neuronal cells induced by Alzheimer's β-amyloid protein are blocked by estradiol and cholesterol Cell. Mol. Neurobiol. 21 2001 1 13
15. F.W. Pfieger Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? BioEssays 25 2003 72 78
16. M.A. Smith, P.L. Richey Harris, L.M. Sayre, J.S. Beckman, and G. Perry Widespread peroxynitrite-mediated damage in Alzheimer's disease J. Neurosci. 17 1997 2653 2657
17. S. Varadarajan, S. Yatin, M. Aksenova, and D.A. Butterfield Alzheimer's amyloid β-peptide-associated free radical oxidative stress and neurotoxicity J. Struct. Biol. 30 2000 184 208
18. C. Cecchi, S. Latorraca, S. Sorbi, T. Iantomasi, F. Favilli, M.T. Vincenzini, and G. Liguri Glutathione level is altered in lymphoblasts from patients with familial Alzheimer's disease Neurosci. Lett. 275 1999 152 154
19. G.E. Gibson, L.C. Park, K.F. Sheu, J.P. Blass, and N.Y. Calingasan The β-ketoglutarate dehydrogenase complex in neurodegeneration Neurochem. Int. 36 2000 97 112
20. L. Tretter, and V. Adam-Vizi Inhibition of Krebs cycle enzymes by hydrogen peroxide: a key role of β-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress J. Neurosci. 20 2000 8972 8979
21. +-dependent glutamate uptake in rat hippocampal astrocyte cultures J. Neurochem. 67 1996 277 286
22. A. Parpura-Gill, D. Beitz, and E. Uemura The inhibitory effects of beta-amyloid on glutamate and glucose uptakes by cultured astrocytes Brain Res. 754 1997 65 71
23. Bal-Price, Z. Moneer, and G.C. Brown Nitric oxide induces rapid, calcium-dependent release of vesicular glutamate and ATP from cultured rat astrocytes Glia 40 2002 312 323
24. J. Keelan, N.J. Allen, D. Antcliffe, S. Pal, and M.R. Duchen Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane J. Neurosci. Res. 66 2001 873 884
25. R. Dringen, and J. Hirrlinger Glutathione pathways in the brain Biol. Chem. 384 2003 505 516