메뉴 건너뛰기




Volumn 19, Issue 4, 1999, Pages 2903-2912

CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: Involvement of SH2-containing phosphotyrosine phosphatase SHP-1

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD5 ANTIGEN; PHENYLALANINE; PHOSPHOLIPASE C; PHYTOHEMAGGLUTININ; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR; TYROSINE;

EID: 0032936299     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.4.2903     Document Type: Article
Times cited : (163)

References (52)
  • 1
    • 0027379715 scopus 로고
    • Association of an activation inducible serine kinase activity with CD5
    • Alberola-Ila, J., L. Places, F. Lozano, and J. Vives. 1993. Association of an activation inducible serine kinase activity with CD5. J. Immunol. 151:4423-4430.
    • (1993) J. Immunol. , vol.151 , pp. 4423-4430
    • Alberola-Ila, J.1    Places, L.2    Lozano, F.3    Vives, J.4
  • 3
    • 0029787549 scopus 로고    scopus 로고
    • Identification of a novel inducible cell-surface ligand of CD5 on activated lymphocytes
    • Biaconte, L., M. A. Bowen, A. Lim, A. Aruffo, G. Andres, and I. Stamenkovic. 1996. Identification of a novel inducible cell-surface ligand of CD5 on activated lymphocytes. J. Exp. Med. 184:811-819.
    • (1996) J. Exp. Med. , vol.184 , pp. 811-819
    • Biaconte, L.1    Bowen, M.A.2    Lim, A.3    Aruffo, A.4    Andres, G.5    Stamenkovic, I.6
  • 4
    • 0030474683 scopus 로고    scopus 로고
    • CD5-mediated negative regulation of antigen receptor-induced growth signal in B-1 cells
    • Bikah, G., J. Carey, J. R. Ciallella, A. Tarakhovsky, and S. Bondada. 1996. CD5-mediated negative regulation of antigen receptor-induced growth signal in B-1 cells. Science 274:1906-1909.
    • (1996) Science , vol.274 , pp. 1906-1909
    • Bikah, G.1    Carey, J.2    Ciallella, J.R.3    Tarakhovsky, A.4    Bondada, S.5
  • 6
    • 0026648995 scopus 로고
    • CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor ζ chain/CD3 and protein-tyrosine kinases p56lck and p59fyn
    • Burgess, K. E., M. Yamamoto, K. V. S. Prasad, and C. E. Rudd. 1992. CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor ζ chain/CD3 and protein-tyrosine kinases p56lck and p59fyn. Proc. Natl. Acad. Sci. USA 89:9311-9315.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9311-9315
    • Burgess, K.E.1    Yamamoto, M.2    Prasad, K.V.S.3    Rudd, C.E.4
  • 7
    • 0023127468 scopus 로고
    • Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to the Leu-1 + B cell subset
    • Casali, P., S. E. Burastero, M. Nakamura, G. Inghirami, and A. L. Notkins. 1987. Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to the Leu-1 + B cell subset. Science 236:77-81.
    • (1987) Science , vol.236 , pp. 77-81
    • Casali, P.1    Burastero, S.E.2    Nakamura, M.3    Inghirami, G.4    Notkins, A.L.5
  • 8
    • 0030240113 scopus 로고    scopus 로고
    • The CD5/CD72 receptor system is coexpressed with several functionally relevant counterstructures on human B cells and delivers a critical signaling activity
    • Cerutti, A., L. Trentin, R. Zambello, R. Sancetta, A. Milani, C. Tassinari, F. Adami, C. Agostini, and G. Semenzato. 1996. The CD5/CD72 receptor system is coexpressed with several functionally relevant counterstructures on human B cells and delivers a critical signaling activity. J. Immunol. 157:1854-1862.
    • (1996) J. Immunol. , vol.157 , pp. 1854-1862
    • Cerutti, A.1    Trentin, L.2    Zambello, R.3    Sancetta, R.4    Milani, A.5    Tassinari, C.6    Adami, F.7    Agostini, C.8    Semenzato, G.9
  • 9
    • 0022539521 scopus 로고
    • Monoclonal antibodies to the CD5 antigen can provide the necessary second signal for activation of isolated resting T cells by solid-phase bound OKT3
    • Ceuppens, J. L., and M. L. Baroja. 1986. Monoclonal antibodies to the CD5 antigen can provide the necessary second signal for activation of isolated resting T cells by solid-phase bound OKT3. J. Immunol. 137:1816-1821.
    • (1986) J. Immunol. , vol.137 , pp. 1816-1821
    • Ceuppens, J.L.1    Baroja, M.L.2
  • 10
    • 0028961264 scopus 로고
    • Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection
    • Cyster, J. G., and C. C. Goodenow. 1995. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity 2:13-24.
    • (1995) Immunity , vol.2 , pp. 13-24
    • Cyster, J.G.1    Goodenow, C.C.2
  • 11
    • 0032055828 scopus 로고    scopus 로고
    • Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
    • Cornall, R. J., J. C. Cyster, M. L. Hibbs, A. R. Dunn, K. L. Otipoby, E. A. Clark, and C. C. Goodenow. 1998. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection. Immunity 8:497-508.
    • (1998) Immunity , vol.8 , pp. 497-508
    • Cornall, R.J.1    Cyster, J.C.2    Hibbs, M.L.3    Dunn, A.R.4    Otipoby, K.L.5    Clark, E.A.6    Goodenow, C.C.7
  • 12
    • 0028932411 scopus 로고
    • Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gammaRIIB1
    • D'Ambrosio, D., K. L. Hippen, S. A. Minskoff, I. Mellman, G. Pani, K. A. Siminovitch, and J. C. Cambier. 1995. Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gammaRIIB1. Science 268:293-297.
    • (1995) Science , vol.268 , pp. 293-297
    • D'Ambrosio, D.1    Hippen, K.L.2    Minskoff, S.A.3    Mellman, I.4    Pani, G.5    Siminovitch, K.A.6    Cambier, J.C.7
  • 13
    • 0026690521 scopus 로고
    • CD5 is phosphorylated on tyrosine after stimulation of the T-cell antigen receptor complex
    • Davies, A. A., S. C. Ley, and M. J. Crumpton. 1992. CD5 is phosphorylated on tyrosine after stimulation of the T-cell antigen receptor complex. Proc. Natl. Acad. Sci. USA 89:6368-6372.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6368-6372
    • Davies, A.A.1    Ley, S.C.2    Crumpton, M.J.3
  • 14
    • 0031053410 scopus 로고    scopus 로고
    • Thymocyte activation induces the association of phosphatidylinositol 3-kinase and pp120 with CD5
    • Dennehy, K. M., R. Broszeit, D. Garnett, G. A. Durrheim, L. L. Spruyt, and A. D. Beyers. 1997. Thymocyte activation induces the association of phosphatidylinositol 3-kinase and pp120 with CD5. Eur. J. Immunol. 27:679-686.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 679-686
    • Dennehy, K.M.1    Broszeit, R.2    Garnett, D.3    Durrheim, G.A.4    Spruyt, L.L.5    Beyers, A.D.6
  • 16
    • 0345518491 scopus 로고
    • Molecular cloning of Ly-1, a membrane glycoprotein of mouse T lymphocytes and a subset of B cells: Molecular homology to the human counterpart Leu-1/T1 (CD5)
    • Huang, H. J. S., N. H. Jones, J. L. Strominger, and L. A. Herzenberg. 1987. Molecular cloning of Ly-1, a membrane glycoprotein of mouse T lymphocytes and a subset of B cells: molecular homology to the human counterpart Leu-1/T1 (CD5). Proc. Natl. Acad. Sci. USA 84:204-208.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 204-208
    • Huang, H.J.S.1    Jones, N.H.2    Strominger, J.L.3    Herzenberg, L.A.4
  • 17
    • 0022460709 scopus 로고
    • Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1
    • Jones, N. H., M. L. Clabby, D. P. Dialynas, H. J. S. Huang, L. A. Herzenberg, and J. L. Strominger. 1986. Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1. Nature 323:346-349.
    • (1986) Nature , vol.323 , pp. 346-349
    • Jones, N.H.1    Clabby, M.L.2    Dialynas, D.P.3    Huang, H.J.S.4    Herzenberg, L.A.5    Strominger, J.L.6
  • 18
    • 0023178409 scopus 로고
    • CD5 antibodies increase intracellular ionized calcium concentration in T cells
    • June, C. H., P. S. Ravinovitch, and J. A. Ledbetter. 1987. CD5 antibodies increase intracellular ionized calcium concentration in T cells. J. Immunol. 138:2782-2792.
    • (1987) J. Immunol. , vol.138 , pp. 2782-2792
    • June, C.H.1    Ravinovitch, P.S.2    Ledbetter, J.A.3
  • 19
    • 0026590085 scopus 로고
    • CD2/LFA3 ligation induces phospholipase-Cγ1 tyrosine phosphorylation and regulates CD3 signaling
    • Kanner, S. B., N. K. Damle, J. Blake, A. A. Aruffo, and J. A. Ledbetter. 1992. CD2/LFA3 ligation induces phospholipase-Cγ1 tyrosine phosphorylation and regulates CD3 signaling. J. Immunol. 148:2023-2029.
    • (1992) J. Immunol. , vol.148 , pp. 2023-2029
    • Kanner, S.B.1    Damle, N.K.2    Blake, J.3    Aruffo, A.A.4    Ledbetter, J.A.5
  • 20
    • 0028956353 scopus 로고
    • Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of Jak2 and termination of proliferative signals
    • Klingmuller, U., U. Lorenz, L. C. Cantley, B. G. Neel, and H. F. Lodish. 1995. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of Jak2 and termination of proliferative signals. Cell 80:729-738.
    • (1995) Cell , vol.80 , pp. 729-738
    • Klingmuller, U.1    Lorenz, U.2    Cantley, L.C.3    Neel, B.G.4    Lodish, H.F.5
  • 21
    • 0025177343 scopus 로고
    • Type 1 macrophage scavenger receptor contains alpha helical and collagen-like coiled coils
    • Kodama, T., L. Freeman, J. Rohrer, J. Zabrecky, P. Matsudaira, and M. Krieger. 1990. Type 1 macrophage scavenger receptor contains alpha helical and collagen-like coiled coils. Nature 343:531-535.
    • (1990) Nature , vol.343 , pp. 531-535
    • Kodama, T.1    Freeman, L.2    Rohrer, J.3    Zabrecky, J.4    Matsudaira, P.5    Krieger, M.6
  • 22
    • 0027359495 scopus 로고
    • Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice
    • Kozlowski, M., I. Mlinaric-Rascan, G. S. Feng, R. Shen, T. Pawson, and K. A. Siminovitch. 1993. Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice. J. Exp. Med. 178:2157-2163.
    • (1993) J. Exp. Med. , vol.178 , pp. 2157-2163
    • Kozlowski, M.1    Mlinaric-Rascan, I.2    Feng, G.S.3    Shen, R.4    Pawson, T.5    Siminovitch, K.A.6
  • 23
    • 0031944075 scopus 로고    scopus 로고
    • Natural killer receptors
    • Lanier, L. L. 1998. Natural killer receptors. Annu. Rev. Immunol. 16:359-393.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 359-393
    • Lanier, L.L.1
  • 25
    • 0001689806 scopus 로고
    • Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes
    • Ledbetter, J. A., C. H. June, L. S. Grosmaire, and P. S. Rabinovitch. 1987. Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes. Proc. Natl. Acad. Sci. USA 84:1384-1388.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1384-1388
    • Ledbetter, J.A.1    June, C.H.2    Grosmaire, L.S.3    Rabinovitch, P.S.4
  • 26
    • 0022593141 scopus 로고
    • Valency of CD3 binding and internalization of the CD3 cell-surface complex control T cell responses to second signals: Distinction between effects on protein kinase C, cytoplasmic free calcium, and proliferation
    • Ledbetter, J. A., C. H. June, P. J. Martin, C. E. Spooner, J. A. Hansen, and K. E. Meier. 1986. Valency of CD3 binding and internalization of the CD3 cell-surface complex control T cell responses to second signals: distinction between effects on protein kinase C, cytoplasmic free calcium, and proliferation. J. Immunol. 136:3945-3952.
    • (1986) J. Immunol. , vol.136 , pp. 3945-3952
    • Ledbetter, J.A.1    June, C.H.2    Martin, P.J.3    Spooner, C.E.4    Hansen, J.A.5    Meier, K.E.6
  • 27
    • 0029844309 scopus 로고    scopus 로고
    • Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness
    • Lorenz, U., K. S. Ravichandran, S. F. Burakoff, and B. J. Neel. 1996. Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness. Proc. Natl. Acad. Sci. USA 93:9624-9629.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9624-9629
    • Lorenz, U.1    Ravichandran, K.S.2    Burakoff, S.F.3    Neel, B.J.4
  • 28
    • 0026550649 scopus 로고
    • Ly-1 (CD5), a membrane glycoprotein of mouse T lymphocytes and a subset of B cells, is a natural ligand of the B cell surface protein Lyb-2 (CD72)
    • Luo, W., H. van de Velde, I. von Hoegen, J. R. Parnes, and K. Thielemans. 1992. Ly-1 (CD5), a membrane glycoprotein of mouse T lymphocytes and a subset of B cells, is a natural ligand of the B cell surface protein Lyb-2 (CD72). J. Immunol. 148:1630-1634.
    • (1992) J. Immunol. , vol.148 , pp. 1630-1634
    • Luo, W.1    Van De Velde, H.2    Von Hoegen, I.3    Parnes, J.R.4    Thielemans, K.5
  • 29
    • 0032584235 scopus 로고    scopus 로고
    • Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor: Loss of SHP-1 expression in human T-lymphotropic virus type I-transformed cells
    • Migone, T. S., N. A. Cacalano, N. Taylor, T. Yi, T. A. Waldmann, and J. A. Johnston. 1998. Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor: loss of SHP-1 expression in human T-lymphotropic virus type I-transformed cells. Proc. Natl. Acad. Sci. USA 95:3845-3850.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3845-3850
    • Migone, T.S.1    Cacalano, N.A.2    Taylor, N.3    Yi, T.4    Waldmann, T.A.5    Johnston, J.A.6
  • 30
    • 0030744134 scopus 로고    scopus 로고
    • Role of phosphatases in lymphocyte activation
    • Neel, B. G. 1997. Role of phosphatases in lymphocyte activation. Curr. Opin. Immunol. 9:405-420.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 405-420
    • Neel, B.G.1
  • 32
    • 0026489920 scopus 로고
    • Evidence for an association between the T cell receptor/CD3 antigen complex and the CD5 antigen in human T lymphocytes
    • Osman, N., S. C. Ley, and M. J. Crumpton. 1992. Evidence for an association between the T cell receptor/CD3 antigen complex and the CD5 antigen in human T lymphocytes. Eur. J. Immunol. 22:2995-3000.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2995-3000
    • Osman, N.1    Ley, S.C.2    Crumpton, M.J.3
  • 34
    • 0029787216 scopus 로고    scopus 로고
    • Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase
    • Pani, G., K.-D. Fischer, I. Mlinaric-Rascan, and K. A. Siminovitch. 1996. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase. J. Exp. Med. 184:839-852.
    • (1996) J. Exp. Med. , vol.184 , pp. 839-852
    • Pani, G.1    Fischer, K.-D.2    Mlinaric-Rascan, I.3    Siminovitch, K.A.4
  • 36
    • 0028004319 scopus 로고
    • Anti-CD5 therapy decreases severity of established disease in collagen type II-induced arthritis in DBA/1 mice
    • Plater-Zyberk, C., P. C. Taylor, M. G. Blaylock, and R. N. Maini. 1994. Anti-CD5 therapy decreases severity of established disease in collagen type II-induced arthritis in DBA/1 mice. Clin. Exp. Immunol. 98:442-447.
    • (1994) Clin. Exp. Immunol. , vol.98 , pp. 442-447
    • Plater-Zyberk, C.1    Taylor, P.C.2    Blaylock, M.G.3    Maini, R.N.4
  • 38
    • 0024358445 scopus 로고
    • Induction of T cell function via the gp33/27 activation inducer molecule (AIM) requires co-expression of the CD3/TcR complex
    • Rincon, M., M. Cebrian, F. Sanchez-Madrid, and M. Lopez-Botet. 1989. Induction of T cell function via the gp33/27 activation inducer molecule (AIM) requires co-expression of the CD3/TcR complex. Eur. J. Immunol. 19:959-962.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 959-962
    • Rincon, M.1    Cebrian, M.2    Sanchez-Madrid, F.3    Lopez-Botet, M.4
  • 39
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling on CD22-deficient mice
    • Sato, S., A. S. Miller, M. Inaoki, C. B. Bock, P. J. Jansen, M. L. Tang, and T. F. Tedder. 1996. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling on CD22-deficient mice. Immunity 5:551-562.
    • (1996) Immunity , vol.5 , pp. 551-562
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3    Bock, C.B.4    Jansen, P.J.5    Tang, M.L.6    Tedder, T.F.7
  • 40
    • 0027417482 scopus 로고
    • Stimulatory effect of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events
    • Secrist, J. P., L. A. Burns, L. Karnitz, G. A. Koretzky, and R. T. Abraham. 1993. Stimulatory effect of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. J. Biol. Chem. 268:5886-5893.
    • (1993) J. Biol. Chem. , vol.268 , pp. 5886-5893
    • Secrist, J.P.1    Burns, L.A.2    Karnitz, L.3    Koretzky, G.A.4    Abraham, R.T.5
  • 41
    • 0027197067 scopus 로고
    • Mutations at the murine motheaten locus are within the haematopoietic cell protein-tyrosine phosphatase (Hcph) gene
    • Shultz, L. D., P. A. Schweitzer, T. V. Rajan, T. Yi, J. N. Ihle, R. J. Matthews, M. L. Thomas, and D. R. Beier. 1993. Mutations at the murine motheaten locus are within the haematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 73:1445-1454.
    • (1993) Cell , vol.73 , pp. 1445-1454
    • Shultz, L.D.1    Schweitzer, P.A.2    Rajan, T.V.3    Yi, T.4    Ihle, J.N.5    Matthews, R.J.6    Thomas, M.L.7    Beier, D.R.8
  • 42
    • 0025966849 scopus 로고
    • Induction of human T cell proliferation by a monoclonal antibody to CD5
    • Spertini, F., W. Stohl, N. Ramesh, C. Moody, and R. S. Geha. 1991. Induction of human T cell proliferation by a monoclonal antibody to CD5. J. Immunol. 146:47-52.
    • (1991) J. Immunol. , vol.146 , pp. 47-52
    • Spertini, F.1    Stohl, W.2    Ramesh, N.3    Moody, C.4    Geha, R.S.5
  • 43
    • 0029871115 scopus 로고    scopus 로고
    • Characterization of mouse CD6 with novel monoclonal antibodies which enhance the allogeneic mixed leukocyte reaction
    • Starling, G. C., G. S. Whitney, A. W. Siadak, M. C. Llewellyn, M. A. Bowen, A. G. Farr, and A. Aruffo. 1996. Characterization of mouse CD6 with novel monoclonal antibodies which enhance the allogeneic mixed leukocyte reaction. Eur. J. Immunol. 26:738-746.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 738-746
    • Starling, G.C.1    Whitney, G.S.2    Siadak, A.W.3    Llewellyn, M.C.4    Bowen, M.A.5    Farr, A.G.6    Aruffo, A.7
  • 44
    • 0026723296 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis in Lewis rats by treatment with an anti-rat CD5 antibody (OX19)
    • Sun, D., K. Branum, and Q. Sun. 1992. Prevention of experimental autoimmune encephalomyelitis in Lewis rats by treatment with an anti-rat CD5 antibody (OX19). Cell. Immunol. 145:263-271.
    • (1992) Cell. Immunol. , vol.145 , pp. 263-271
    • Sun, D.1    Branum, K.2    Sun, Q.3
  • 46
    • 0031835658 scopus 로고    scopus 로고
    • Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages
    • Timms, J. F., D. Carlberg, H. Gu, H. Chen, S. Kamatkar, M. J. Nadler, L. R. Rohrscheider, and B. G. Neel. 1998. Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages. Mol. Cell. Biol. 18:3838-3850.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3838-3850
    • Timms, J.F.1    Carlberg, D.2    Gu, H.3    Chen, H.4    Kamatkar, S.5    Nadler, M.J.6    Rohrscheider, L.R.7    Neel, B.G.8
  • 47
    • 0027195626 scopus 로고
    • Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene
    • Tsui, H. W., K. A. Siminovitch, L. de Souza, and F. W. Tsui. 1993. Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene. Nat. Genet. 4:124-129.
    • (1993) Nat. Genet. , vol.4 , pp. 124-129
    • Tsui, H.W.1    Siminovitch, K.A.2    De Souza, L.3    Tsui, F.W.4
  • 48
    • 0029944192 scopus 로고    scopus 로고
    • Engagement of the adhesion receptor CD22 triggers a potent stimulatory signal for B cells and blocking CD22/CD22L interactions impairs T-cell proliferation
    • Tuskano, J., P. Engel, T. F. Tedder, and J. H. Kehrl. 1996. Engagement of the adhesion receptor CD22 triggers a potent stimulatory signal for B cells and blocking CD22/CD22L interactions impairs T-cell proliferation. Blood 87:4723-4730.
    • (1996) Blood , vol.87 , pp. 4723-4730
    • Tuskano, J.1    Engel, P.2    Tedder, T.F.3    Kehrl, J.H.4
  • 49
    • 0030053270 scopus 로고    scopus 로고
    • Involvement of p72 syk kinase, p53/56 lyn kinase and phosphatidyl inositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22
    • Tuskano, J. M., P. Engel, T. F. Tedder, A. Argarwa, and J. H. Kehrl. 1996. Involvement of p72 syk kinase, p53/56 lyn kinase and phosphatidyl inositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22. Eur. J. Immunol. 26:1246-1252.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1246-1252
    • Tuskano, J.M.1    Engel, P.2    Tedder, T.F.3    Argarwa, A.4    Kehrl, J.H.5
  • 50
    • 0030873248 scopus 로고    scopus 로고
    • Inhibitory receptors, ITIM sequences and phosphatases
    • Unkeless, J. C., and J. Lin. 1997. Inhibitory receptors, ITIM sequences and phosphatases. Curr. Top. Immunol. 9:338-343.
    • (1997) Curr. Top. Immunol. , vol.9 , pp. 338-343
    • Unkeless, J.C.1    Lin, J.2
  • 52
    • 0027488637 scopus 로고
    • Hemopoietic cell phosphatase associates with the interleukin (IL-3) receptor B chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis
    • Yi, T., A. L. Mui, G. Krystal, and J. N. Ihle. 1993. Hemopoietic cell phosphatase associates with the interleukin (IL-3) receptor B chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis. Mol. Cell. Biol. 13:7577-7586.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7577-7586
    • Yi, T.1    Mui, A.L.2    Krystal, G.3    Ihle, J.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.