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Volumn 26, Issue 1, 2010, Pages 16-25

Heroes or villains? T regulatory cells in malaria infection

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RECEPTOR 2;

EID: 72149128886     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2009.10.004     Document Type: Review
Times cited : (61)

References (85)
  • 2
    • 0034068284 scopus 로고    scopus 로고
    • Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster
    • WHO. Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster. Trans. R. Soc. Trop. Med. Hyg. 94 Suppl 1 (2000) S1-90
    • (2000) Trans. R. Soc. Trop. Med. Hyg. , vol.94 , Issue.SUPPL. 1
    • WHO1
  • 3
    • 45549097494 scopus 로고    scopus 로고
    • Immunity to malaria: more questions than answers
    • Langhorne J., et al. Immunity to malaria: more questions than answers. Nat. Immunol. 9 (2008) 725-732
    • (2008) Nat. Immunol. , vol.9 , pp. 725-732
    • Langhorne, J.1
  • 4
    • 0019916356 scopus 로고
    • Malaria and alterations in immune reactivity
    • Weidanz W.P. Malaria and alterations in immune reactivity. Br. Med. Bull. 38 (1982) 167-172
    • (1982) Br. Med. Bull. , vol.38 , pp. 167-172
    • Weidanz, W.P.1
  • 5
    • 33847072270 scopus 로고    scopus 로고
    • Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function
    • Millington O.R., et al. Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function. J. Biol. 5 (2006) 5
    • (2006) J. Biol. , vol.5 , pp. 5
    • Millington, O.R.1
  • 6
    • 34547749066 scopus 로고    scopus 로고
    • Emerging challenges in regulatory T cell function and biology
    • Sakaguchi S., and Powrie F. Emerging challenges in regulatory T cell function and biology. Science 317 (2007) 627-629
    • (2007) Science , vol.317 , pp. 627-629
    • Sakaguchi, S.1    Powrie, F.2
  • 7
    • 34748873441 scopus 로고    scopus 로고
    • Regulatory T cells and infection: a dangerous necessity
    • Belkaid Y. Regulatory T cells and infection: a dangerous necessity. Nat. Rev. Immunol. 7 (2007) 875-888
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 875-888
    • Belkaid, Y.1
  • 8
    • 29744458971 scopus 로고    scopus 로고
    • Reduced cord blood immune effector-cell responsiveness mediated by CD4+ cells induced in utero as a consequence of placental Plasmodium falciparum infection
    • Brustoski K., et al. Reduced cord blood immune effector-cell responsiveness mediated by CD4+ cells induced in utero as a consequence of placental Plasmodium falciparum infection. J. Infect. Dis. 193 (2006) 146-154
    • (2006) J. Infect. Dis. , vol.193 , pp. 146-154
    • Brustoski, K.1
  • 9
    • 24944466472 scopus 로고    scopus 로고
    • Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection
    • Walther M., et al. Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity 23 (2005) 287-296
    • (2005) Immunity , vol.23 , pp. 287-296
    • Walther, M.1
  • 10
    • 66349138519 scopus 로고    scopus 로고
    • Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria
    • Minigo G., et al. Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria. PLoS Pathogens 5 (2009) e1000402
    • (2009) PLoS Pathogens , vol.5
    • Minigo, G.1
  • 11
    • 58149252417 scopus 로고    scopus 로고
    • Plasmodium vivax parasites alter the balance of myeloid and plasmacytoid dendritic cells and the induction of regulatory T cells
    • Jangpatarapongsa K., et al. Plasmodium vivax parasites alter the balance of myeloid and plasmacytoid dendritic cells and the induction of regulatory T cells. Eur. J. Immunol. 38 (2008) 2697-2705
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2697-2705
    • Jangpatarapongsa, K.1
  • 12
    • 33947640163 scopus 로고    scopus 로고
    • Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice
    • Couper K.N., et al. Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice. J. Immunol. 178 (2007) 4136-4146
    • (2007) J. Immunol. , vol.178 , pp. 4136-4146
    • Couper, K.N.1
  • 13
    • 40349089873 scopus 로고    scopus 로고
    • IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection
    • Couper K.N., et al. IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. PLoS Pathogens 4 (2008) e1000004
    • (2008) PLoS Pathogens , vol.4
    • Couper, K.N.1
  • 14
    • 29744440462 scopus 로고    scopus 로고
    • Resistance of regulatory T cells to glucocorticoid-viduced TNFR family-related protein (GITR) during Plasmodium yoelii infection
    • Hisaeda H., et al. Resistance of regulatory T cells to glucocorticoid-viduced TNFR family-related protein (GITR) during Plasmodium yoelii infection. Eur. J. Immunol. 35 (2005) 3516-3524
    • (2005) Eur. J. Immunol. , vol.35 , pp. 3516-3524
    • Hisaeda, H.1
  • 15
    • 42149134289 scopus 로고    scopus 로고
    • Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells
    • Hisaeda H., et al. Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells. J. Immunol. 180 (2008) 2496-2503
    • (2008) J. Immunol. , vol.180 , pp. 2496-2503
    • Hisaeda, H.1
  • 16
    • 34250811023 scopus 로고    scopus 로고
    • Plasmodium yoelii: distinct CD4(+)CD25(+) regulatory T cell responses during the early stages of infection in susceptible and resistant mice
    • Wu Y., et al. Plasmodium yoelii: distinct CD4(+)CD25(+) regulatory T cell responses during the early stages of infection in susceptible and resistant mice. Exp. Parasitol. 115 (2007) 301-304
    • (2007) Exp. Parasitol. , vol.115 , pp. 301-304
    • Wu, Y.1
  • 17
    • 70350026790 scopus 로고    scopus 로고
    • Effects of CD4+CD25+Foxp3+ regulatory T cells on early Plasmodium yoelii 17XL infection in BALB/c mice
    • Chen G., et al. Effects of CD4+CD25+Foxp3+ regulatory T cells on early Plasmodium yoelii 17XL infection in BALB/c mice. Parasitology 136 (2009) 1107-1120
    • (2009) Parasitology , vol.136 , pp. 1107-1120
    • Chen, G.1
  • 18
    • 61649087617 scopus 로고    scopus 로고
    • The shiitake mushroom-derived immuno-stimulant lentinan protects against murine malaria blood-stage infection by evoking adaptive immune-responses
    • Zhou L.D., et al. The shiitake mushroom-derived immuno-stimulant lentinan protects against murine malaria blood-stage infection by evoking adaptive immune-responses. Int. Immunopharmacol. 9 (2009) 455-462
    • (2009) Int. Immunopharmacol. , vol.9 , pp. 455-462
    • Zhou, L.D.1
  • 19
    • 70350542601 scopus 로고    scopus 로고
    • Concurrent infection with Heligmosomoides polygyrus suppresses anti-Plasmodium yoelii protection partially by induction of CD4(+)CD25(+)Foxp3(+) Treg in mice
    • Tetsutani K., et al. Concurrent infection with Heligmosomoides polygyrus suppresses anti-Plasmodium yoelii protection partially by induction of CD4(+)CD25(+)Foxp3(+) Treg in mice. Eur. J. Immunol. 39 (2009) 2822-2830
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2822-2830
    • Tetsutani, K.1
  • 20
    • 34249947689 scopus 로고    scopus 로고
    • Regulatory CD4+ CD25+ Foxp3+ T cells expand during experimental Plasmodium infection but do not prevent cerebral malaria
    • Vigario A.M., et al. Regulatory CD4+ CD25+ Foxp3+ T cells expand during experimental Plasmodium infection but do not prevent cerebral malaria. Int. J. Parasitol. 37 (2007) 963-973
    • (2007) Int. J. Parasitol. , vol.37 , pp. 963-973
    • Vigario, A.M.1
  • 21
    • 37249093662 scopus 로고    scopus 로고
    • Natural regulatory (CD4(+)CD25(+)FOXP(+)) T cells control the production of pro-inflammatory cytokines during Plasmodium chabaudi adami infection and do not contribute to immune evasion
    • Cambos M., et al. Natural regulatory (CD4(+)CD25(+)FOXP(+)) T cells control the production of pro-inflammatory cytokines during Plasmodium chabaudi adami infection and do not contribute to immune evasion. Int. J. Parasitol. 38 (2008) 229-238
    • (2008) Int. J. Parasitol. , vol.38 , pp. 229-238
    • Cambos, M.1
  • 22
    • 66349085903 scopus 로고    scopus 로고
    • Distinct roles for FOXP3+ and FOXP3- CD4+ T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria
    • Walther M., et al. Distinct roles for FOXP3+ and FOXP3- CD4+ T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria. PLoS Pathogens 5 (2009) e1000364
    • (2009) PLoS Pathogens , vol.5
    • Walther, M.1
  • 23
    • 70049100538 scopus 로고    scopus 로고
    • Plasmodium falciparum-mediated induction of human CD25hiFoxp3hi CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFbeta
    • Scholzen A., et al. Plasmodium falciparum-mediated induction of human CD25hiFoxp3hi CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFbeta. PLoS Pathogens 5 (2009) e1000543
    • (2009) PLoS Pathogens , vol.5
    • Scholzen, A.1
  • 24
    • 66349124294 scopus 로고    scopus 로고
    • Homeostatic regulation of T effector to Treg ratios in an area of seasonal malaria transmission
    • Finney O.C., et al. Homeostatic regulation of T effector to Treg ratios in an area of seasonal malaria transmission. Eur. J. Immunol. 39 (2009) 1288-1300
    • (2009) Eur. J. Immunol. , vol.39 , pp. 1288-1300
    • Finney, O.C.1
  • 25
    • 70350614503 scopus 로고    scopus 로고
    • Bisseye, C. et al. (2009) Plasmodium falciparum infection of the placenta impacts on the T helper type 1 (Th1)/Th2 balance of neonatal T cells through CD4+CD25+ forkhead box P3+ regulatory T cells and interleukin-10. Clin. Exp. Immunol. (in press), Aug 17. [Epub ahead of print].
    • Bisseye, C. et al. (2009) Plasmodium falciparum infection of the placenta impacts on the T helper type 1 (Th1)/Th2 balance of neonatal T cells through CD4+CD25+ forkhead box P3+ regulatory T cells and interleukin-10. Clin. Exp. Immunol. (in press), Aug 17. [Epub ahead of print].
  • 26
    • 0036047222 scopus 로고    scopus 로고
    • Mouse models for erythrocytic-stage malaria
    • Sanni L.A., et al. Mouse models for erythrocytic-stage malaria. Methods Mol. Med. 72 (2002) 57-76
    • (2002) Methods Mol. Med. , vol.72 , pp. 57-76
    • Sanni, L.A.1
  • 27
    • 33645233847 scopus 로고    scopus 로고
    • Insights into the immunopathogenesis of malaria using mouse models
    • Lamb T.J., et al. Insights into the immunopathogenesis of malaria using mouse models. Expert Rev. Mol. Med. 8 (2006) 1-22
    • (2006) Expert Rev. Mol. Med. , vol.8 , pp. 1-22
    • Lamb, T.J.1
  • 28
    • 0037292478 scopus 로고    scopus 로고
    • Influence of CD4+CD25+ T cells on Plasmodium berghei NK65 infection in BALB/c mice
    • Long T.T., et al. Influence of CD4+CD25+ T cells on Plasmodium berghei NK65 infection in BALB/c mice. Int. J. Parasitol. 33 (2003) 175-183
    • (2003) Int. J. Parasitol. , vol.33 , pp. 175-183
    • Long, T.T.1
  • 29
    • 48249115186 scopus 로고    scopus 로고
    • Cerebral malaria in children is associated with long-term cognitive impairment
    • John C.C., et al. Cerebral malaria in children is associated with long-term cognitive impairment. Pediatrics 122 (2008) e92-99
    • (2008) Pediatrics , vol.122
    • John, C.C.1
  • 30
    • 22144489827 scopus 로고    scopus 로고
    • BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25- responder T cells than C57BL/6 mice
    • Chen X., et al. BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25- responder T cells than C57BL/6 mice. J. Leukoc. Biol. 78 (2005) 114-121
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 114-121
    • Chen, X.1
  • 31
    • 38449113583 scopus 로고    scopus 로고
    • Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host
    • Griffith J.W., et al. Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host. J. Infect. Dis. 196 (2007) 1553-1564
    • (2007) J. Infect. Dis. , vol.196 , pp. 1553-1564
    • Griffith, J.W.1
  • 32
    • 34248345515 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis
    • Nie C.Q., et al. CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis. Infect. Immun. 75 (2007) 2275-2282
    • (2007) Infect. Immun. , vol.75 , pp. 2275-2282
    • Nie, C.Q.1
  • 33
    • 1842455770 scopus 로고    scopus 로고
    • Escape of malaria parasites from host immunity requires CD4+ CD25+ regulatory T cells
    • Hisaeda H., et al. Escape of malaria parasites from host immunity requires CD4+ CD25+ regulatory T cells. Nat. Med. 10 (2004) 29-30
    • (2004) Nat. Med. , vol.10 , pp. 29-30
    • Hisaeda, H.1
  • 34
    • 34548319120 scopus 로고    scopus 로고
    • A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria
    • Amante F.H., et al. A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria. Am. J. Pathol. 171 (2007) 548-559
    • (2007) Am. J. Pathol. , vol.171 , pp. 548-559
    • Amante, F.H.1
  • 35
    • 46449104448 scopus 로고    scopus 로고
    • Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities
    • Randall L.M., et al. Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities. Infect. Immun. 76 (2008) 3312-3320
    • (2008) Infect. Immun. , vol.76 , pp. 3312-3320
    • Randall, L.M.1
  • 36
    • 44349150336 scopus 로고    scopus 로고
    • Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4+CD25+ T cells with susceptibility in Kenyans
    • Todryk S.M., et al. Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4+CD25+ T cells with susceptibility in Kenyans. PLoS ONE 3 (2008) e2027
    • (2008) PLoS ONE , vol.3
    • Todryk, S.M.1
  • 37
    • 38649117867 scopus 로고    scopus 로고
    • Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria
    • Torcia M.G., et al. Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 646-651
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 646-651
    • Torcia, M.G.1
  • 38
    • 20144386970 scopus 로고    scopus 로고
    • Different antibody- and cytokine-mediated responses to Plasmodium falciparum parasite in two sympatric ethnic tribes living in Mali
    • Farouk S.E., et al. Different antibody- and cytokine-mediated responses to Plasmodium falciparum parasite in two sympatric ethnic tribes living in Mali. Microbes Infect. 7 (2005) 110-117
    • (2005) Microbes Infect. , vol.7 , pp. 110-117
    • Farouk, S.E.1
  • 39
    • 45549102822 scopus 로고    scopus 로고
    • Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells
    • Chen X., et al. Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells. J. Immunol. 180 (2008) 6467-6471
    • (2008) J. Immunol. , vol.180 , pp. 6467-6471
    • Chen, X.1
  • 40
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?
    • Curotto de Lafaille M.A., and Lafaille J.J. Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?. Immunity 30 (2009) 626-635
    • (2009) Immunity , vol.30 , pp. 626-635
    • Curotto de Lafaille, M.A.1    Lafaille, J.J.2
  • 41
    • 15244340167 scopus 로고    scopus 로고
    • Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion
    • Zelenay S., et al. Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 4091-4096
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 4091-4096
    • Zelenay, S.1
  • 42
    • 44849133287 scopus 로고    scopus 로고
    • The critical contribution of TGF-beta to the induction of Foxp3 expression and regulatory T cell function
    • Shevach E.M., et al. The critical contribution of TGF-beta to the induction of Foxp3 expression and regulatory T cell function. Eur. J. Immunol. 38 (2008) 915-917
    • (2008) Eur. J. Immunol. , vol.38 , pp. 915-917
    • Shevach, E.M.1
  • 43
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
    • Levings M.K., et al. The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int. Arch. Allergy Immunol. 129 (2002) 263-276
    • (2002) Int. Arch. Allergy Immunol. , vol.129 , pp. 263-276
    • Levings, M.K.1
  • 44
    • 0242410967 scopus 로고    scopus 로고
    • Differential induction of TGF-beta regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections
    • Omer F.M., et al. Differential induction of TGF-beta regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections. J. Immunol. 171 (2003) 5430-5436
    • (2003) J. Immunol. , vol.171 , pp. 5430-5436
    • Omer, F.M.1
  • 45
    • 0030841167 scopus 로고    scopus 로고
    • Interleukin-10 modulates susceptibility in experimental cerebral malaria
    • Kossodo S., et al. Interleukin-10 modulates susceptibility in experimental cerebral malaria. Immunology 91 (1997) 536-540
    • (1997) Immunology , vol.91 , pp. 536-540
    • Kossodo, S.1
  • 46
    • 0032797911 scopus 로고    scopus 로고
    • A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice
    • Li C., et al. A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice. Infect. Immun. 67 (1999) 4435-4442
    • (1999) Infect. Immun. , vol.67 , pp. 4435-4442
    • Li, C.1
  • 47
    • 0041823567 scopus 로고    scopus 로고
    • Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies
    • Li C., et al. Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies. Infect. Immun. 71 (2003) 4850-4856
    • (2003) Infect. Immun. , vol.71 , pp. 4850-4856
    • Li, C.1
  • 48
    • 0032490573 scopus 로고    scopus 로고
    • Transforming growth factor beta production is inversely correlated with severity of murine malaria infection
    • Omer F.M., and Riley E.M. Transforming growth factor beta production is inversely correlated with severity of murine malaria infection. J. Exp. Med. 188 (1998) 39-48
    • (1998) J. Exp. Med. , vol.188 , pp. 39-48
    • Omer, F.M.1    Riley, E.M.2
  • 49
    • 0033823645 scopus 로고    scopus 로고
    • Reduced interleukin-12 and transforming growth factor-beta1 in severe childhood malaria: relationship of cytokine balance with disease severity
    • Perkins D.J., et al. Reduced interleukin-12 and transforming growth factor-beta1 in severe childhood malaria: relationship of cytokine balance with disease severity. J. Infect. Dis. 182 (2000) 988-992
    • (2000) J. Infect. Dis. , vol.182 , pp. 988-992
    • Perkins, D.J.1
  • 50
    • 33845713177 scopus 로고    scopus 로고
    • Immunomodulatory role of chloroquine and pyrimethamine in Plasmodium yoelii 17XL infected mice
    • Ramos-Avila A., et al. Immunomodulatory role of chloroquine and pyrimethamine in Plasmodium yoelii 17XL infected mice. Scand. J. Immunol. 65 (2007) 54-62
    • (2007) Scand. J. Immunol. , vol.65 , pp. 54-62
    • Ramos-Avila, A.1
  • 51
    • 23844535777 scopus 로고    scopus 로고
    • Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration
    • Franke-Fayard B., et al. Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 11468-11473
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 11468-11473
    • Franke-Fayard, B.1
  • 52
    • 54149093896 scopus 로고    scopus 로고
    • What really happens to dendritic cells during malaria?
    • Wykes M.N., and Good M.F. What really happens to dendritic cells during malaria?. Nat. Rev. 6 (2008) 864-870
    • (2008) Nat. Rev. , vol.6 , pp. 864-870
    • Wykes, M.N.1    Good, M.F.2
  • 53
    • 33747143361 scopus 로고    scopus 로고
    • From vanilla to 28 flavors: multiple varieties of T regulatory cells
    • Shevach E.M. From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 25 (2006) 195-201
    • (2006) Immunity , vol.25 , pp. 195-201
    • Shevach, E.M.1
  • 54
    • 36249024247 scopus 로고    scopus 로고
    • Regulatory T cells - a brief history and perspective
    • Sakaguchi S., et al. Regulatory T cells - a brief history and perspective. Eur. J. Immunol. 37 Suppl. 1 (2007) S116-123
    • (2007) Eur. J. Immunol. , vol.37 , Issue.SUPPL. 1
    • Sakaguchi, S.1
  • 55
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
    • Tang Q., and Bluestone J.A. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat. Immunol. 9 (2008) 239-244
    • (2008) Nat. Immunol. , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 56
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • Zheng Y., and Rudensky A.Y. Foxp3 in control of the regulatory T cell lineage. Nat. Immunol. 8 (2007) 457-462
    • (2007) Nat. Immunol. , vol.8 , pp. 457-462
    • Zheng, Y.1    Rudensky, A.Y.2
  • 57
    • 34447575642 scopus 로고    scopus 로고
    • Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection
    • Finney C.A., et al. Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection. Eur. J. Immunol. 37 (2007) 1874-1886
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1874-1886
    • Finney, C.A.1
  • 58
    • 34848877883 scopus 로고    scopus 로고
    • Despite increased CD4+Foxp3+ cells within the infection site, BALB/c IL-4 receptor-deficient mice reveal CD4+Foxp3-negative T cells as a source of IL-10 in Leishmania major susceptibility
    • Nagase H., et al. Despite increased CD4+Foxp3+ cells within the infection site, BALB/c IL-4 receptor-deficient mice reveal CD4+Foxp3-negative T cells as a source of IL-10 in Leishmania major susceptibility. J. Immunol. 179 (2007) 2435-2444
    • (2007) J. Immunol. , vol.179 , pp. 2435-2444
    • Nagase, H.1
  • 59
    • 1242290580 scopus 로고    scopus 로고
    • Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10
    • Zheng S.G., et al. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. J. Immunol. 172 (2004) 5213-5221
    • (2004) J. Immunol. , vol.172 , pp. 5213-5221
    • Zheng, S.G.1
  • 60
    • 51049101255 scopus 로고    scopus 로고
    • CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner
    • Andersson J., et al. CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner. J. Exp. Med. 205 (2008) 1975-1981
    • (2008) J. Exp. Med. , vol.205 , pp. 1975-1981
    • Andersson, J.1
  • 61
    • 34249660624 scopus 로고    scopus 로고
    • Chronic helminth infections induce immunomodulation: consequences and mechanisms
    • van Riet E., et al. Chronic helminth infections induce immunomodulation: consequences and mechanisms. Immunobiology 212 (2007) 475-490
    • (2007) Immunobiology , vol.212 , pp. 475-490
    • van Riet, E.1
  • 62
    • 53549125796 scopus 로고    scopus 로고
    • Immune interactions in malaria co-infections with other endemic infectious diseases: implications for the development of improved disease interventions
    • Troye-Blomberg M., and Berzins K. Immune interactions in malaria co-infections with other endemic infectious diseases: implications for the development of improved disease interventions. Microbes Infect. 10 (2008) 948-952
    • (2008) Microbes Infect. , vol.10 , pp. 948-952
    • Troye-Blomberg, M.1    Berzins, K.2
  • 63
    • 67649138829 scopus 로고    scopus 로고
    • Regulatory T cells in the control of host-microorganism interactions
    • Belkaid Y., and Tarbell K. Regulatory T cells in the control of host-microorganism interactions. Annu. Rev. Immunol. 27 (2009) 551-589
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 551-589
    • Belkaid, Y.1    Tarbell, K.2
  • 64
    • 0348223800 scopus 로고    scopus 로고
    • Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule
    • Omer F.M., et al. Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule. J. Exp. Med. 198 (2003) 1817-1827
    • (2003) J. Exp. Med. , vol.198 , pp. 1817-1827
    • Omer, F.M.1
  • 65
    • 0344643400 scopus 로고    scopus 로고
    • Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages
    • Gantt K.R., et al. Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages. J. Immunol. 170 (2003) 2613-2620
    • (2003) J. Immunol. , vol.170 , pp. 2613-2620
    • Gantt, K.R.1
  • 66
    • 65549123258 scopus 로고    scopus 로고
    • Responses to malarial antigens are altered in helminth-infected children
    • Hartgers F.C., et al. Responses to malarial antigens are altered in helminth-infected children. J. Infect. Dis. 199 (2009) 1528-1535
    • (2009) J. Infect. Dis. , vol.199 , pp. 1528-1535
    • Hartgers, F.C.1
  • 67
    • 33646858976 scopus 로고    scopus 로고
    • Worms can alter T cell responses and induce regulatory T cells to experimental malaria vaccines
    • Druilhe P., et al. Worms can alter T cell responses and induce regulatory T cells to experimental malaria vaccines. Vaccine 24 (2006) 4902-4904
    • (2006) Vaccine , vol.24 , pp. 4902-4904
    • Druilhe, P.1
  • 68
    • 19744364625 scopus 로고    scopus 로고
    • Impairment of protective immunity to blood-stage malaria by concurrent nematode infection
    • Su Z., et al. Impairment of protective immunity to blood-stage malaria by concurrent nematode infection. Infect. Immun. 73 (2005) 3531-3539
    • (2005) Infect. Immun. , vol.73 , pp. 3531-3539
    • Su, Z.1
  • 69
    • 62949212581 scopus 로고    scopus 로고
    • Short report: Childhood coinfections with Plasmodium falciparum and Schistosoma mansoni result in lower percentages of activated T cells and T regulatory memory cells than schistosomiasis only
    • Muok E.M., et al. Short report: Childhood coinfections with Plasmodium falciparum and Schistosoma mansoni result in lower percentages of activated T cells and T regulatory memory cells than schistosomiasis only. Am. J. Trop. Med. Hyg. 80 (2009) 475-478
    • (2009) Am. J. Trop. Med. Hyg. , vol.80 , pp. 475-478
    • Muok, E.M.1
  • 70
    • 34250864955 scopus 로고    scopus 로고
    • Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells
    • Chen X., et al. Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells. J. Immunol. 179 (2007) 154-161
    • (2007) J. Immunol. , vol.179 , pp. 154-161
    • Chen, X.1
  • 71
    • 0028823314 scopus 로고
    • Prediction of accelerated cure in Plasmodium falciparum malaria by the elevated capacity of tumor necrosis factor production
    • Kremsner P.G., et al. Prediction of accelerated cure in Plasmodium falciparum malaria by the elevated capacity of tumor necrosis factor production. Am. J. Trop. Med. Hyg. 53 (1995) 532-538
    • (1995) Am. J. Trop. Med. Hyg. , vol.53 , pp. 532-538
    • Kremsner, P.G.1
  • 72
    • 0042329758 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha in the pathogenesis of cerebral malaria
    • Gimenez F., et al. Tumor necrosis factor alpha in the pathogenesis of cerebral malaria. Cell Mol. Life Sci. 60 (2003) 1623-1635
    • (2003) Cell Mol. Life Sci. , vol.60 , pp. 1623-1635
    • Gimenez, F.1
  • 73
    • 42949162462 scopus 로고    scopus 로고
    • Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators
    • van Mierlo G.J., et al. Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators. J. Immunol. 180 (2008) 2747-2751
    • (2008) J. Immunol. , vol.180 , pp. 2747-2751
    • van Mierlo, G.J.1
  • 74
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu J., et al. Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat. Immunol. 3 (2002) 135-142
    • (2002) Nat. Immunol. , vol.3 , pp. 135-142
    • Shimizu, J.1
  • 75
    • 34548598702 scopus 로고    scopus 로고
    • Toll-like receptors and immune regulation: their direct and indirect modulation on regulatory CD4+ CD25+ T cells
    • Liu G., and Zhao Y. Toll-like receptors and immune regulation: their direct and indirect modulation on regulatory CD4+ CD25+ T cells. Immunology 122 (2007) 149-156
    • (2007) Immunology , vol.122 , pp. 149-156
    • Liu, G.1    Zhao, Y.2
  • 76
    • 33845868751 scopus 로고    scopus 로고
    • Pathological role of Toll-like receptor signaling in cerebral malaria
    • Coban C., et al. Pathological role of Toll-like receptor signaling in cerebral malaria. Int. Immunol. 19 (2007) 67-79
    • (2007) Int. Immunol. , vol.19 , pp. 67-79
    • Coban, C.1
  • 77
    • 34250866255 scopus 로고    scopus 로고
    • Murine cerebral malaria development is independent of toll-like receptor signaling
    • Togbe D., et al. Murine cerebral malaria development is independent of toll-like receptor signaling. Am. J. Pathol. 170 (2007) 1640-1648
    • (2007) Am. J. Pathol. , vol.170 , pp. 1640-1648
    • Togbe, D.1
  • 78
    • 33846611019 scopus 로고    scopus 로고
    • TLR9 ligand enhances proliferation of rat CD4+ T cell and modulates suppressive activity mediated by CD4+ CD25+ T cell
    • Chiffoleau E., et al. TLR9 ligand enhances proliferation of rat CD4+ T cell and modulates suppressive activity mediated by CD4+ CD25+ T cell. Int. Immunol. 19 (2007) 193-201
    • (2007) Int. Immunol. , vol.19 , pp. 193-201
    • Chiffoleau, E.1
  • 79
    • 4644327023 scopus 로고    scopus 로고
    • Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells
    • Moseman E.A., et al. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. J. Immunol. 173 (2004) 4433-4442
    • (2004) J. Immunol. , vol.173 , pp. 4433-4442
    • Moseman, E.A.1
  • 80
    • 19944430901 scopus 로고    scopus 로고
    • Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
    • Coban C., et al. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J. Exp. Med. 201 (2005) 19-25
    • (2005) J. Exp. Med. , vol.201 , pp. 19-25
    • Coban, C.1
  • 81
    • 33846911691 scopus 로고    scopus 로고
    • Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
    • Parroche P., et al. Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 1919-1924
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 1919-1924
    • Parroche, P.1
  • 82
    • 11144358459 scopus 로고    scopus 로고
    • Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway
    • Pichyangkul S., et al. Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway. J. Immunol. 172 (2004) 4926-4933
    • (2004) J. Immunol. , vol.172 , pp. 4926-4933
    • Pichyangkul, S.1
  • 83
    • 37149055076 scopus 로고    scopus 로고
    • Expression of toll-like receptors on antigen-presenting cells in patients with falciparum malaria
    • Loharungsikul S., et al. Expression of toll-like receptors on antigen-presenting cells in patients with falciparum malaria. Acta Tropica 105 (2008) 10-15
    • (2008) Acta Tropica , vol.105 , pp. 10-15
    • Loharungsikul, S.1
  • 84
    • 34250658895 scopus 로고    scopus 로고
    • Role of TGF-beta and PGE2 in T cell responses during Plasmodium yoelii infection
    • Ocana-Morgner C., et al. Role of TGF-beta and PGE2 in T cell responses during Plasmodium yoelii infection. Eur. J. Immunol. 37 (2007) 1562-1574
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1562-1574
    • Ocana-Morgner, C.1
  • 85
    • 8444245925 scopus 로고    scopus 로고
    • Toll-dependent control mechanisms of CD4 T cell activation
    • Pasare C., and Medzhitov R. Toll-dependent control mechanisms of CD4 T cell activation. Immunity 21 (2004) 733-741
    • (2004) Immunity , vol.21 , pp. 733-741
    • Pasare, C.1    Medzhitov, R.2


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