메뉴 건너뛰기




Volumn 104, Issue 2, 2009, Pages 211-220

Immunopathology in ocular toxoplasmosis: Facts and clues

Author keywords

Acquired toxoplasmosis; Chemokines; Congenitally contracted toxoplasmosis; Cytokines; Experimental autoimmune uveitis; Ocular toxoplasmosis

Indexed keywords


EID: 65549146491     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762009000200014     Document Type: Article
Times cited : (48)

References (91)
  • 1
    • 33847667225 scopus 로고    scopus 로고
    • The role of T helper 17 (T(H)-17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
    • Afzali B, Lombardi G, Lechler RI, Lord GM 2007. The role of T helper 17 (T(H)-17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 148: 32-46.
    • (2007) Clin Exp Immunol , vol.148 , pp. 32-46
    • Afzali, B.1    Lombardi, G.2    Lechler, R.I.3    Lord, G.M.4
  • 5
    • 0034988745 scopus 로고    scopus 로고
    • Effects of cytokines and prolactin on the replication of Toxoplasma gondii in murine microglia
    • Benedetto N, Folgore A, Romano Carratelli C, Galdiero F 2001. Effects of cytokines and prolactin on the replication of Toxoplasma gondii in murine microglia. Eur Cytokine Netw 12: 348-358.
    • (2001) Eur Cytokine Netw , vol.12 , pp. 348-358
    • Benedetto, N.1    Folgore, A.2    Romano Carratelli, C.3    Galdiero, F.4
  • 6
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector T(H)-17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK 2006. Reciprocal developmental pathways for the generation of pathogenic effector T(H)-17 and regulatory T cells. Nature 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 7
    • 34248572345 scopus 로고    scopus 로고
    • T(H)-17 cells in the circle of immunity and autoimmunity
    • Bettelli E, Oukka M, Kuchroo VK 2007 T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol 8: 345-350.
    • (2007) Nat Immunol , vol.8 , pp. 345-350
    • Bettelli, E.1    Oukka, M.2    Kuchroo, V.K.3
  • 8
    • 52049119781 scopus 로고    scopus 로고
    • Serum and aqueous humour cytokine response and histopathological alterations during ocular Toxoplasma gondii infection in C57BL/6 mice
    • Calabrese KS, Tedesco RC, Zaverucha do Valle T, Barbosa HS 2008. Serum and aqueous humour cytokine response and histopathological alterations during ocular Toxoplasma gondii infection in C57BL/6 mice. Micron 39: 1335-1341.
    • (2008) Micron , vol.39 , pp. 1335-1341
    • Calabrese, K.S.1    Tedesco, R.C.2    Zaverucha do Valle, T.3    Barbosa, H.S.4
  • 9
    • 33748745741 scopus 로고    scopus 로고
    • Ocular immunity: Price of privilege
    • Caspi RR 2006. Ocular immunity: price of privilege. Immunol Res 213: 23-35.
    • (2006) Immunol Res , vol.213 , pp. 23-35
    • Caspi, R.R.1
  • 11
    • 0017643717 scopus 로고
    • Immunosuppression and eye disease. First vail lecture
    • Cogan DG 1977. Immunosuppression and eye disease. First vail lecture. Am J Ophthalmol 83: 777-788.
    • (1977) Am J Ophthalmol , vol.83 , pp. 777-788
    • Cogan, D.G.1
  • 13
    • 0043172378 scopus 로고    scopus 로고
    • IL-23 and IL-27: New members of the growing family of il-12-related cytokines with important implications for therapeutics
    • Cordoba-Rodriguez R, Frucht DM 2003. IL-23 and IL-27: new members of the growing family of IL-12-related cytokines with important implications for therapeutics. Expert Opin Biol Ther 3: 715-723.
    • (2003) Expert Opin Biol Ther , vol.3 , pp. 715-723
    • Cordoba-Rodriguez, R.1    Frucht, D.M.2
  • 14
    • 0037621613 scopus 로고    scopus 로고
    • Mice with neonatally induced inactivation of the vascular cell adhesion molecule-1 fail to control the parasite in Toxoplasma encephalitis
    • Deckert M, Lütjen S, Leuker CE, Kwok LY, Strack A, Müller W, Wagner N, Schlüter D 2003. Mice with neonatally induced inactivation of the vascular cell adhesion molecule-1 fail to control the parasite in Toxoplasma encephalitis. Eur J Immunol 33: 1418-1428.
    • (2003) Eur J Immunol , vol.33 , pp. 1418-1428
    • Deckert, M.1    Lütjen, S.2    Leuker, C.E.3    Kwok, L.Y.4    Strack, A.5    Müller, W.6    Wagner, N.7    Schlüter, D.8
  • 16
    • 33645318217 scopus 로고    scopus 로고
    • Diversification of T-helper-cell lineages: Finding the family root of il-17-producing (T(H)-17) cells
    • Dong C 2006. Diversification of T-helper-cell lineages: finding the family root of IL-17-producing (T(H)-17) cells. Nat Rev Immunol 6: 329-333.
    • (2006) Nat Rev Immunol , vol.6 , pp. 329-333
    • Dong, C.1
  • 18
    • 33645708607 scopus 로고    scopus 로고
    • Systemic T cell response to Toxoplasma gondii antigen in patients with ocular toxoplasmosis
    • Fatoohi F, Cozon GJ, Wallon M, Kodjikian L, Peyron F 2006. Systemic T cell response to Toxoplasma gondii antigen in patients with ocular toxoplasmosis. Jpn J Ophthalmol 50: 103-110.
    • (2006) Jpn J Ophthalmol , vol.50 , pp. 103-110
    • Fatoohi, F.1    Cozon, G.J.2    Wallon, M.3    Kodjikian, L.4    Peyron, F.5
  • 19
    • 0035651008 scopus 로고    scopus 로고
    • Characterization of Toxoplasma gondii-specific T cells recovered from vitreous fluid of patients with ocular toxoplasmosis
    • Feron EJ, Klaren VN, Wierenga EA, Verjans GM, Kijlstra A 2001. Characterization of Toxoplasma gondii-specific T cells recovered from vitreous fluid of patients with ocular toxoplasmosis. Invest Ophthalmol Vis Sci 42: 3228-3232.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 3228-3232
    • Feron, E.J.1    Klaren, V.N.2    Wierenga, E.A.3    Verjans, G.M.4    Kijlstra, A.5
  • 21
    • 0024546494 scopus 로고
    • Naturally occurring antibodies to bovine and human retinal S antigen: A comparison between uveitis patients and healthy volunteers
    • Forrester JV, Stott DI, Hercus KM 1989. Naturally occurring antibodies to bovine and human retinal S antigen: a comparison between uvei- tis patients and healthy volunteers. Br J Ophthalmol 73: 155-159.
    • (1989) Br J Ophthalmol , vol.73 , pp. 155-159
    • Forrester, J.V.1    Stott, D.I.2    Hercus, K.M.3
  • 23
    • 33947134461 scopus 로고    scopus 로고
    • Cytokine regulation of immunopathology in toxoplasmosis
    • Gaddi PJ, Yap GS 2007. Cytokine regulation of immunopathology in toxoplasmosis. Immunol Cell Biol 85: 155-159.
    • (2007) Immunol Cell Biol , vol.85 , pp. 155-159
    • Gaddi, P.J.1    Yap, G.S.2
  • 24
    • 0023726442 scopus 로고
    • Production of specific retinal S antigen antibodies in patients with retinal detachment
    • García H, Dante C, Calderon G, Antonio P 1988. Production of specific retinal S antigen antibodies in patients with retinal detachment. Graefes Arch Clin Exp Ophthalmol 226: 428-430.
    • (1988) Graefes Arch Clin Exp Ophthalmol , vol.226 , pp. 428-430
    • García, H.1    Dante, C.2    Calderon, G.3    Antonio, P.4
  • 25
    • 0028235657 scopus 로고
    • Toxoplasma gondii: Acquired ocular toxoplasmosis in the murine model, protective role of TNF-alpha and IFN-gamma
    • Gazzinelli RT, Brézin A, Li Q, Nussenblatt RB, Chan CC 1994. Toxoplasma gondii: acquired ocular toxoplasmosis in the murine model, protective role of TNF-alpha and IFN-gamma. Exp Parasitol 78: 217-229.
    • (1994) Exp Parasitol , vol.78 , pp. 217-229
    • Gazzinelli, R.T.1    Brézin, A.2    Li, Q.3    Nussenblatt, R.B.4    Chan, C.C.5
  • 28
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4(+) effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT 2005. Interleukin 17-producing CD4(+) effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6: 1123-1132.
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 33
    • 21844444831 scopus 로고    scopus 로고
    • New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
    • Hunter CA 2005. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat Rev Immunol 5: 521-531.
    • (2005) Nat Rev Immunol , vol.5 , pp. 521-531
    • Hunter, C.A.1
  • 35
    • 39749173780 scopus 로고    scopus 로고
    • The blood-brain barrier induces differentiation of migrating monocytes into T(H)-17-polarizing dendritic cells
    • Ifergan I, Kébir H, Bernard M, Wosik K, Dodelet-Devillers A, Cayrol R, Arbour N, Prat A 2008. The blood-brain barrier induces differentiation of migrating monocytes into T(H)-17-polarizing dendritic cells. Brain 131: 785-799.
    • (2008) Brain , vol.131 , pp. 785-799
    • Ifergan, I.1    Kébir, H.2    Bernard, M.3    Wosik, K.4    Dodelet-Devillers, A.5    Cayrol, R.6    Arbour, N.7    Prat, A.8
  • 36
    • 33646417072 scopus 로고    scopus 로고
    • The IL-23/IL-17 axis in inflammation
    • Iwakura Y, Ishigame H 2006. The IL-23/IL-17 axis in inflammation. J Clin Invest 116: 1218-1222.
    • (2006) J Clin Invest , vol.116 , pp. 1218-1222
    • Iwakura, Y.1    Ishigame, H.2
  • 38
    • 53149143166 scopus 로고    scopus 로고
    • Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis
    • Ke Y, Jiang G, Sun D, Kaplan HJ, Shao H 2008. Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis. Invest Ophthalmol Vis Sci 49: 3999-4007.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 3999-4007
    • Ke, Y.1    Jiang, G.2    Sun, D.3    Kaplan, H.J.4    Shao, H.5
  • 40
    • 11144286392 scopus 로고    scopus 로고
    • Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection
    • Kelly MN, Kolls JK, Happel K, Schwartzman JD, Schwarzenberger P, Combe C, Moretto M, Khan IA 2005. Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun 73: 617-621.
    • (2005) Infect Immun , vol.73 , pp. 617-621
    • Kelly, M.N.1    Kolls, J.K.2    Happel, K.3    Schwartzman, J.D.4    Schwarzenberger, P.5    Combe, C.6    Moretto, M.7    Khan, I.A.8
  • 41
    • 0025118151 scopus 로고
    • Humoral and cellular immune reactions against retinal antigens in clinical disease
    • Kijlstra A, Hoekzema R, vd Lelij A, Doekes G, Rothova A 1990. Humoral and cellular immune reactions against retinal antigens in clinical disease. Curr Eye Res 9 (Suppl.): 85-89.
    • (1990) Curr Eye Res , vol.9 , Issue.SUPPL. , pp. 85-89
    • Kijlstra, A.1    Hoekzema, R.2    vd Lelij, A.3    Doekes, G.4    Rothova, A.5
  • 42
    • 0035575971 scopus 로고    scopus 로고
    • Evidence for a compartmentalized B cell response as characterized by IgG epitope specificity in human ocular toxoplasmosis
    • Klaren VN, Peek R 2001. Evidence for a compartmentalized B cell response as characterized by IgG epitope specificity in human ocular toxoplasmosis. J Immunol 167: 6263-6269.
    • (2001) J Immunol , vol.167 , pp. 6263-6269
    • Klaren, V.N.1    Peek, R.2
  • 43
    • 0025992505 scopus 로고
    • Humoral immune response to retinal S-antigen in patients with uveitis
    • Klass M, Böhnke M, Damms T, Knospe V 1991. Humoral immune response to retinal S-antigen in patients with uveitis. Fortschr Ophthalmol 88: 450-454.
    • (1991) Fortschr Ophthalmol , vol.88 , pp. 450-454
    • Klass, M.1    Böhnke, M.2    Damms, T.3    Knospe, V.4
  • 44
    • 13844264119 scopus 로고    scopus 로고
    • The effect of Toxoplasma gondii infection on expression of chemokines by rat retinal vascular endothelial cells
    • Knight BC, Brunton CL, Modi NC, Wallace GR, Stanford MR 2005. The effect of Toxoplasma gondii infection on expression of chemokines by rat retinal vascular endothelial cells. J Neuroimmunol 160: 41-47.
    • (2005) J Neuroimmunol , vol.160 , pp. 41-47
    • Knight, B.C.1    Brunton, C.L.2    Modi, N.C.3    Wallace, G.R.4    Stanford, M.R.5
  • 46
    • 34548651152 scopus 로고    scopus 로고
    • Cutting edge: Opposite effects of IL-1 and IL-2 on the regulation of IL-17+T cell pool IL-1 subverts IL-2-mediated suppression
    • Kryczek I, Wei S, Vatan L, Escara-Wilke J, Szeliga W, Keller ET, Zou W 2007. Cutting edge: opposite effects of IL-1 and IL-2 on the regulation of IL-17+T cell pool IL-1 subverts IL-2-mediated suppression. J Immunol 179: 1423-1426.
    • (2007) J Immunol , vol.179 , pp. 1423-1426
    • Kryczek, I.1    Wei, S.2    Vatan, L.3    Escara-Wilke, J.4    Szeliga, W.5    Keller, E.T.6    Zou, W.7
  • 49
    • 23344452972 scopus 로고    scopus 로고
    • Experimental ocular toxoplasmosis in genetically susceptible and resistant mice
    • Lu F, Huang S, Hu MS, Kasper LH 2005. Experimental ocular toxoplasmosis in genetically susceptible and resistant mice. Infect Immun 73: 5160-5165.
    • (2005) Infect Immun , vol.73 , pp. 5160-5165
    • Lu, F.1    Huang, S.2    Hu, M.S.3    Kasper, L.H.4
  • 50
    • 0344420100 scopus 로고    scopus 로고
    • Interleukin-10 and pathogenesis of murine ocular toxoplasmosis
    • Lu F, Huang S, Kasper LH 2003. Interleukin-10 and pathogenesis of murine ocular toxoplasmosis. Infect Immun 71: 7159-7163.
    • (2003) Infect Immun , vol.71 , pp. 7159-7163
    • Lu, F.1    Huang, S.2    Kasper, L.H.3
  • 51
    • 4544328679 scopus 로고    scopus 로고
    • CD4(+) T cells in the pathogenesis of murine ocular toxoplasmosis
    • Lu F, Huang S, Kasper LH 2004. CD4(+) T cells in the pathogenesis of murine ocular toxoplasmosis. Infect Immun 72: 4966-4972.
    • (2004) Infect Immun , vol.72 , pp. 4966-4972
    • Lu, F.1    Huang, S.2    Kasper, L.H.3
  • 52
    • 42449154999 scopus 로고    scopus 로고
    • New perspectives on effector mechanism in uveitis
    • Luger D, Caspi RR 2008. New perspectives on effector mechanism in uveitis. Semin Immunopathol 30: 135-143.
    • (2008) Semin Immunopathol , vol.30 , pp. 135-143
    • Luger, D.1    Caspi, R.R.2
  • 53
    • 0035077592 scopus 로고    scopus 로고
    • Immunological studies of chronic ocular toxoplasmosis: Up-regulation of major histocompatibility complex class I and transforming growth factor beta and a protective role for interleukin-6
    • Lyons RE, Anthony JP, Ferguson DJ, Byrne N, Alexander J, Roberts F, Roberts CW 2001. Immunological studies of chronic ocular toxoplasmosis: up-regulation of major histocompatibility complex class I and transforming growth factor beta and a protective role for interleukin-6. Infect Immun 69: 2589-2595.
    • (2001) Infect Immun , vol.69 , pp. 2589-2595
    • Lyons, R.E.1    Anthony, J.P.2    Ferguson, D.J.3    Byrne, N.4    Alexander, J.5    Roberts, F.6    Roberts, C.W.7
  • 56
    • 33751103431 scopus 로고    scopus 로고
    • Cytokine production of CD8+immune T cells but not of CD4(+) T cells from Toxoplasma gondii-infected mice is polarized to a type 1 response following stimulation with tachyzoite-infected macrophages
    • Miller R, Wen X, Dunford B, Wang X, Suzuki Y 2006. Cytokine production of CD8+immune T cells but not of CD4(+) T cells from Toxoplasma gondii-infected mice is polarized to a type 1 response following stimulation with tachyzoite-infected macrophages. J Interferon Cytokine Res 26: 787-792.
    • (2006) J Interferon Cytokine Res , vol.26 , pp. 787-792
    • Miller, R.1    Wen, X.2    Dunford, B.3    Wang, X.4    Suzuki, Y.5
  • 59
    • 0032869354 scopus 로고    scopus 로고
    • The importance of specific IgG and IgE autoantibodies to retinal S antigen, total serum IgE, and sCD23 levels in autoimmune and infectious uveitis
    • Muiño JC, Juárez CP, Luna JD, Castro CC, Wolff EG, Ferrero M, Romero-Piffiguer MD 1999. The importance of specific IgG and IgE autoantibodies to retinal S antigen, total serum IgE, and sCD23 levels in autoimmune and infectious uveitis. J Clin Immunol 19: 215-222.
    • (1999) J Clin Immunol , vol.19 , pp. 215-222
    • Muiño, J.C.1    Juárez, C.P.2    Luna, J.D.3    Castro, C.C.4    Wolff, E.G.5    Ferrero, M.6    Romero-Piffiguer, M.D.7
  • 61
    • 0033964730 scopus 로고    scopus 로고
    • Toxoplasma gondii infection induces gene expression and secretion of interleukin 1 (IL-1), IL- 6, granulocyte-macrophage colony-stimulating factor, and inter-cellular adhesion molecule 1 by human retinal pigment epithelial cells
    • Nagineni CN, Detrick B, Hooks JJ 2000. Toxoplasma gondii infection induces gene expression and secretion of interleukin 1 (IL-1), IL- 6, granulocyte-macrophage colony-stimulating factor, and inter-cellular adhesion molecule 1 by human retinal pigment epithelial cells. Infect Immun 68: 407-410
    • (2000) Infect Immun , vol.68 , pp. 407-410
    • Nagineni, C.N.1    Detrick, B.2    Hooks, J.J.3
  • 62
    • 0036091906 scopus 로고    scopus 로고
    • Transforming growth factor-beta expression in human retinal pigment epithelial cells is enhanced by Toxoplasma gondii: A possible role in the immunopathogenesis of retinochoroiditis
    • Nagineni CN, Detrick B, Hooks JJ 2002. Transforming growth factor-beta expression in human retinal pigment epithelial cells is enhanced by Toxoplasma gondii: a possible role in the immunopathogenesis of retinochoroiditis. Clin Exp Immunol 128: 372-378.
    • (2002) Clin Exp Immunol , vol.128 , pp. 372-378
    • Nagineni, C.N.1    Detrick, B.2    Hooks, J.J.3
  • 63
    • 0029797005 scopus 로고    scopus 로고
    • Mechanisms of interferon-induced inhibition of Toxoplasma gondii replication in human retinal pigment epithelial cells
    • Nagineni CN, Pardhasaradhi K, Martins MC, Detrick B, Hooks JJ 1996. Mechanisms of interferon-induced inhibition of Toxoplasma gondii replication in human retinal pigment epithelial cells. Infect Immun 64: 4188-4196.
    • (1996) Infect Immun , vol.64 , pp. 4188-4196
    • Nagineni, C.N.1    Pardhasaradhi, K.2    Martins, M.C.3    Detrick, B.4    Hooks, J.J.5
  • 64
    • 34447567140 scopus 로고    scopus 로고
    • IL-27 controls the development of inducible regulatory T cells and T(H)-17 cells via differential effects on STAT1
    • Neufert C, Becker C, Wirtz S, Fantini MC, Weigmann B, Galle PR, Neurath MF 2007. IL-27 controls the development of inducible regulatory T cells and T(H)-17 cells via differential effects on STAT1. Eur J Immunol 37: 1809-1816.
    • (2007) Eur J Immunol , vol.37 , pp. 1809-1816
    • Neufert, C.1    Becker, C.2    Wirtz, S.3    Fantini, M.C.4    Weigmann, B.5    Galle, P.R.6    Neurath, M.F.7
  • 66
    • 0024349003 scopus 로고
    • Lymphocyte proliferative responses of patients with ocular toxoplasmosis to parasite and retinal antigens
    • Nussenblatt RB, Mittal KK, Fuhrman S, Sharma SD, Palestine AG 1989. Lymphocyte proliferative responses of patients with ocular toxoplasmosis to parasite and retinal antigens. Am J Ophthalmol 107: 632-641.
    • (1989) Am J Ophthalmol , vol.107 , pp. 632-641
    • Nussenblatt, R.B.1    Mittal, K.K.2    Fuhrman, S.3    Sharma, S.D.4    Palestine, A.G.5
  • 67
    • 0021030697 scopus 로고
    • XL Edward Jackson memorial lecture
    • Factors related to the initiation and recurrence of uveitis
    • O'Connor GR. Factors related to the initiation and recurrence of uveitis 1983. XL Edward Jackson memorial lecture. Am J Ophthalmol 96: 577-599.
    • (1983) Am J Ophthalmol , vol.96 , pp. 577-599
    • O'Connor, G.R.1
  • 68
    • 0015140816 scopus 로고
    • Effects of an interferon inducer, poly I:C, on acute ocular infection produced by intracameral inoculation of toxoplasma gondii
    • Oh JO, O'Connor GR 1971. Effects of an interferon inducer, poly I:C, on acute ocular infection produced by intracameral inoculation of Toxoplasma gondii. Infect Immun 4: 407-410.
    • (1971) Infect Immun , vol.4 , pp. 407-410
    • Oh, J.O.1    O'Connor, G.R.2
  • 69
  • 72
    • 0032605382 scopus 로고    scopus 로고
    • Acquired and congenital ocular toxoplasmosis experimentally induced in Calomys callosus (Rodentia, Cricetidae)
    • Pereira Mde F, Silva DA, Ferro EA, Mineo JR 1999. Acquired and congenital ocular toxoplasmosis experimentally induced in Calomys callosus (Rodentia, Cricetidae). Mem Inst Oswaldo Cruz 94: 103-114.
    • (1999) Mem Inst Oswaldo Cruz , vol.94 , pp. 103-114
    • Pereira mde, F.1    Silva, D.A.2    Ferro, E.A.3    Mineo, J.R.4
  • 74
    • 0033079817 scopus 로고    scopus 로고
    • Pathogenesis of toxoplasmic retinochoroiditis
    • Roberts F, McLeod R 1999. Pathogenesis of toxoplasmic retinochoroiditis. Parasitol Today 15: 51-57.
    • (1999) Parasitol Today , vol.15 , pp. 51-57
    • Roberts, F.1    McLeod, R.2
  • 81
    • 3042580051 scopus 로고    scopus 로고
    • Immune responses to retinal self-antigens in CD25(+)CD4(+) regulatory T-cell-depleted mice
    • Takeuchi M, Keino H, Kezuka T, Usui M, Taguchi O 2004. Immune responses to retinal self-antigens in CD25(+)CD4(+) regulatory T-cell-depleted mice. Invest Ophthalmol Vis Sci 45: 1879-1886.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1879-1886
    • Takeuchi, M.1    Keino, H.2    Kezuka, T.3    Usui, M.4    Taguchi, O.5
  • 84
    • 42249115211 scopus 로고    scopus 로고
    • Interleukin-27 suppresses experimental autoimmune encephalomyelitis during bone marrow stromal cell treatment
    • Wang J, Wang G, Sun B, Li H, Mu L, Wang Q, Li G, Shi L, Jin L, Kostulas N 2008. Interleukin-27 suppresses experimental autoimmune encephalomyelitis during bone marrow stromal cell treatment. J Autoimmun 30: 222-229.
    • (2008) J Autoimmun , vol.30 , pp. 222-229
    • Wang, J.1    Wang, G.2    Sun, B.3    Li, H.4    Mu, L.5    Wang, Q.6    Li, G.7    Shi, L.8    Jin, L.9    Kostulas, N.10
  • 85
    • 34547201936 scopus 로고    scopus 로고
    • Microglia produce IFN-gamma independently from T cells during acute toxoplasmosis in the brain
    • Wang X, Suzuki Y 2007. Microglia produce IFN-gamma independently from T cells during acute toxoplasmosis in the brain. J Interferon Cytokine Res 27: 599-605.
    • (2007) J Interferon Cytokine Res , vol.27 , pp. 599-605
    • Wang, X.1    Suzuki, Y.2
  • 88
    • 0019180625 scopus 로고
    • Cellular hypersensitivity to toxoplasmal and retinal antigens in patients with toxoplasma retinochoroiditis
    • Wyler DJ, Blackman HJ, Lunde MN 1980. Cellular hypersensitivity to toxoplasmal and retinal antigens in patients with toxoplasma retinochoroiditis. Am J Trop Med Hyg 29: 1181-1186.
    • (1980) Am J Trop Med Hyg , vol.29 , pp. 1181-1186
    • Wyler, D.J.1    Blackman, H.J.2    Lunde, M.N.3
  • 89
    • 33845388684 scopus 로고    scopus 로고
    • Genetic background influences Th cell differentiation by controlling the capacity for IL-2-induced IL-4 production by naïve CD4(+) T cells
    • Yagi J, Arimura Y, Takatori H, Nakajima H, Iwamoto I, Uchiyama T 2006. Genetic background influences Th cell differentiation by controlling the capacity for IL-2-induced IL-4 production by naïve CD4(+) T cells. Int Immunol 18: 1681-1690.
    • (2006) Int Immunol , vol.18 , pp. 1681-1690
    • Yagi, J.1    Arimura, Y.2    Takatori, H.3    Nakajima, H.4    Iwamoto, I.5    Uchiyama, T.6
  • 90
    • 0032762620 scopus 로고    scopus 로고
    • Cell-mediated immunity to Toxoplasma gondii: Initiation, regulation and effector function
    • Yap GS, Sher A 1999. Cell-mediated immunity to Toxoplasma gondii: initiation, regulation and effector function. Immunobiology 201: 240-247.
    • (1999) Immunobiology , vol.201 , pp. 240-247
    • Yap, G.S.1    Sher, A.2
  • 91
    • 44849130724 scopus 로고    scopus 로고
    • Involvement of Foxp3-expressing CD4(+) CD25+regulatory T cells in the development of tolerance induced by transforming growth factor-beta2-treated antigen-presenting cells
    • Zhang H, Yang P, Zhou H, Meng Q, Huang X 2008. Involvement of Foxp3-expressing CD4(+) CD25+regulatory T cells in the development of tolerance induced by transforming growth factor-beta2-treated antigen-presenting cells. Immunology 124: 304-314.
    • (2008) Immunology , vol.124 , pp. 304-314
    • Zhang, H.1    Yang, P.2    Zhou, H.3    Meng, Q.4    Huang, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.