The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology

PLoS Pathogens

Volumn 8, Issue 2, 2012, Pages

  Hafalla, Julius Clemence R ^a   Claser, Carla ^b   Couper, Kevin N ^a   Grau, Georges Emile ^c   Renia, Laurent ^b   de Souza, J Brian ^a,d   Riley, Eleanor M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b AGENCY FOR SCIENCE   (Singapore)

^c UNIVERSITY OF SYDNEY   (Australia)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; PROGRAMMED DEATH 1 LIGAND 1; CD274 PROTEIN, MOUSE; DIFFERENTIATION ANTIGEN; PD 1 ANTIGEN, MOUSE; PD-1 ANTIGEN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; BRAIN MALARIA; C57BL 6 MOUSE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; HOMEOSTASIS; HOST RESISTANCE; IMMUNE RESPONSE; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; PLASMODIUM BERGHEI INFECTION; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; ERYTHROCYTE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALARIA; METABOLISM; MICROBIOLOGY; PARASITOLOGY; PATHOGENICITY; PATHOLOGY; PLASMODIUM BERGHEI;

MUS; PLASMODIUM BERGHEI;

ANIMALS; ANTIGENS, CD274; ANTIGENS, DIFFERENTIATION; CD8-POSITIVE T-LYMPHOCYTES; CTLA-4 ANTIGEN; ERYTHROCYTES; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MALARIA, CEREBRAL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PLASMODIUM BERGHEI;

EID: 84860898062     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002504     Document Type: Article

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