Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production

Human Genetics

Volumn 124, Issue 5, 2008, Pages 515-524

  Ouma, Collins ^a   Davenport, Gregory C ^b   Were, Tom ^a,c   Otieno, Michael F ^c   Hittner, James B ^d   Vulule, John M ^a   Martinson, Jeremy ^b   Ong'echa, John M ^a,e   Ferrell, Robert E ^b   Perkins, Douglas J ^a,e  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c KENYATTA UNIVERSITY   (Kenya)

^d School of Business   (United States)

^e UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12; TUMOR NECROSIS FACTOR ALPHA;

AFRICA; ANEMIA; ARTICLE; BACTERIAL TRANSMISSION; CHILDHOOD DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; IMMUNOPATHOGENESIS; INFANT; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALARIA; MALE; MORBIDITY; MORTALITY; PEDIATRICS; PHENOTYPE; PLASMODIUM FALCIPARUM; PRESCHOOL CHILD; PRIORITY JOURNAL; PROMOTER REGION; SEVERE MALARIAL ANEMIA;

ANEMIA; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HAPLOTYPES; HUMANS; INFANT; INFLAMMATION MEDIATORS; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-6; KENYA; LINKAGE DISEQUILIBRIUM; MALARIA; MALARIA, FALCIPARUM; MALE; PARASITEMIA; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

PLASMODIUM FALCIPARUM;

EID: 57049122803     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-008-0578-5     Document Type: Article

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