Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events

Neurobiology of Disease

Volumn 62, Issue , 2014, Pages 273-285

  Bhaskar, Kiran ^a   Maphis, Nicole ^a   Xu, Guixiang ^b   Varvel, Nicholas H ^c   Kokiko Cochran, Olga N ^b   Weick, Jason P ^a   Staugaitis, Susan M ^b   Cardona, Astrid ^e   Ransohoff, Richard M ^b   Herrup, Karl ^d   Lamb, Bruce T ^b  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d RUTGERS UNIVERSITY   (United States)

^e UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

Adoptive transfer; Alzheimer's disease; C Jun Kinase (JNK); Microglia; Neuroinflammation; Neuronal cell cycle; Tumor necrosis factor (TNF )

Indexed keywords

AMYLOID BETA PROTEIN; CD11B ANTIGEN; CYCLIN D1; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE TRANSFER; ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL ACTIVATION; CELL CYCLE; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; MICROGLIA; MITOSIS; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEURONAL CELL CYCLE EVENT; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

AD; ADOPTIVE TRANSFER; ALZHEIMER'S DISEASE; AΒF; AΒO; BRDU; BROMODEOXYURIDINE; C-JUN KINASE; C-JUN KINASE (JNK); CCE; CELL CYCLE EVENTS; CM; CONDITIONED MEDIA; COX2; CYCLOOXYGENASE-2; FIBRILLAR AMYLOID-BETA PEPTIDE; GFP; GREEN FLUORESCENT PROTEIN; IDV; IKKΑ/Β; IL-1Β; IL-6; INFΓ; INTEGRATED DENSITY VALUE; INTERFERON-Γ; INTERLEUKIN-1Β; INTERLEUKIN-6; IΚB KINASE Α/Β; JNK; LIPOPOLYSACCHARIDE; LPS; MAP2; MICROGLIA; MICROTUBULE ASSOCIATED PROTEIN-2; NEUROINFLAMMATION; NEURONAL CELL CYCLE; NITRIC OXIDE SYNTHASE; NON-STEROIDAL ANTI-INFLAMMATORY DRUG; NOS; NSAID; OLIGOMERIC AMYLOID-BETA PEPTIDE; P38 MAPK; P38 MITOGEN ACTIVATED PROTEIN KINASE; PARAFORMALDEHYDE; PAS; PBS; PCNA; PFA; PHOSPHATE BUFFERED SALINE; PHOSPHATIDYLINOSITOL 3-KINASE; PI3K; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN-A-SEPHAROSE; REGION OF INTEREST; ROI; ROOM TEMPERATURE; RT; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3; STAT3; TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE DUTP NICK END LABELING; TNF RECEPTOR; TNFR; TNFΑ; TUMOR NECROSIS FACTOR-Α; TUMOR NECROSIS FACTOR-Α (TNFΑ); TUNEL;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL CYCLE; CELLS, CULTURED; FRONTAL LOBE; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; NEURONS; TEMPORAL LOBE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84887174745     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.10.007     Document Type: Article

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