-
2
-
-
67650844275
-
Epidemiology of Alzheimer's disease: Occurrence, determinants, and strategies toward intervention
-
Qiu C, Kivipelto M, von Strauss E. Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention. Dialogues Clin Neurosci 2009;11:111-28.
-
(2009)
Dialogues Clin Neurosci
, vol.11
, pp. 111-128
-
-
Qiu, C.1
Kivipelto, M.2
Von Strauss, E.3
-
3
-
-
84865176138
-
Locus-specific mutation databases for neurodegenerative brain diseases
-
Cruts M, Theuns J, Van Broeckhoven C. Locus-specific mutation databases for neurodegenerative brain diseases. Hum Mutat 2012;33:1340-4.
-
(2012)
Hum Mutat
, vol.33
, pp. 1340-1344
-
-
Cruts, M.1
Theuns, J.2
Van Broeckhoven, C.3
-
4
-
-
77957927865
-
The genetics of Alzheimer disease: Back to the future
-
Bertram L, Lill CM, Tanzi RE. The genetics of Alzheimer disease: back to the future. Neuron 2010;68:270-81.
-
(2010)
Neuron
, vol.68
, pp. 270-281
-
-
Bertram, L.1
Lill, C.M.2
Tanzi, R.E.3
-
5
-
-
0027327267
-
Association of apolipoprotein e allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-72.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
-
6
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 1993;90:1977-81.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
-
7
-
-
79953212557
-
A rare variant in MYH6 is associated with high risk of sick sinus syndrome
-
Holm H, Gudbjartsson DF, Sulem P, et al. A rare variant in MYH6 is associated with high risk of sick sinus syndrome. Nat Genet 2011;43:316-20.
-
(2011)
Nat Genet
, vol.43
, pp. 316-320
-
-
Holm, H.1
Gudbjartsson, D.F.2
Sulem, P.3
-
8
-
-
80055001747
-
Identification of low-frequency variants associated with gout and serum uric acid levels
-
Sulem P, Gudbjartsson DF, Walters GB, et al. Identification of low-frequency variants associated with gout and serum uric acid levels. Nat Genet 2011;43:1127-30.
-
(2011)
Nat Genet
, vol.43
, pp. 1127-1130
-
-
Sulem, P.1
Gudbjartsson, D.F.2
Walters, G.B.3
-
9
-
-
80055009292
-
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
-
Stacey SN, Sulem P, Jonasdottir A, et al. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet 2011;43:1098-103.
-
(2011)
Nat Genet
, vol.43
, pp. 1098-1103
-
-
Stacey, S.N.1
Sulem, P.2
Jonasdottir, A.3
-
10
-
-
80054973810
-
Mutations in BRIP1 confer high risk of ovarian cancer
-
Rafnar T, Gudbjartsson DF, Sulem P, et al. Mutations in BRIP1 confer high risk of ovarian cancer. Nat Genet 2011;43:1104-7.
-
(2011)
Nat Genet
, vol.43
, pp. 1104-1107
-
-
Rafnar, T.1
Gudbjartsson, D.F.2
Sulem, P.3
-
11
-
-
84864471159
-
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
-
Jonsson T, Atwal JK, Steinberg S, et al. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 2012;488:96-9.
-
Nature
, vol.2012
, Issue.488
, pp. 96-99
-
-
Jonsson, T.1
Atwal, J.K.2
Steinberg, S.3
-
12
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-44.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
13
-
-
0025072924
-
Designing the national resident assessment instrument for nursing homes
-
Morris JN, Hawes C, Fries BE, et al. Designing the national resident assessment instrument for nursing homes. Gerontologist 1990;30:293-307.
-
(1990)
Gerontologist
, vol.30
, pp. 293-307
-
-
Morris, J.N.1
Hawes, C.2
Fries, B.E.3
-
14
-
-
0030840999
-
Comprehensive clinical assessment in community setting: Applicability of the MDSHC
-
Morris JN, Fries BE, Steel K, et al. Comprehensive clinical assessment in community setting: applicability of the MDSHC. J Am Geriatr Soc 1997;45:1017-24.
-
(1997)
J Am Geriatr Soc
, vol.45
, pp. 1017-1024
-
-
Morris, J.N.1
Fries, B.E.2
Steel, K.3
-
17
-
-
77955426959
-
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
-
Athanasiu L, Mattingsdal M, Kahler AK, et al. Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort. J Psychiatr Res 2010;44:748-53.
-
(2010)
J Psychiatr Res
, vol.44
, pp. 748-753
-
-
Athanasiu, L.1
Mattingsdal, M.2
Kahler, A.K.3
-
19
-
-
80054717387
-
The Rotterdam Study: 2012 Objectives and design update
-
Hofman A, van Duijn CM, Franco OH, et al. The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol 2011;26:657-86.
-
(2011)
Eur J Epidemiol
, vol.26
, pp. 657-686
-
-
Hofman, A.1
Van Duijn, C.M.2
Franco, O.H.3
-
21
-
-
0019993831
-
Immunoglobulins and complement factors in senile plaques: An immunoperoxidase study
-
Eikelenboom P, Stam FC. Immunoglobulins and complement factors in senile plaques: an immunoperoxidase study. Acta Neuropathol 1982;57:239-42.
-
(1982)
Acta Neuropathol
, vol.57
, pp. 239-242
-
-
Eikelenboom, P.1
Stam, F.C.2
-
22
-
-
0021262101
-
Immuno-electron-microscopic localization of complements in amyloid fibrils of senile plaques
-
Ishii T, Haga S. Immuno-electron-microscopic localization of complements in amyloid fibrils of senile plaques. Acta Neuropathol 1984;63:296-300.
-
(1984)
Acta Neuropathol
, vol.63
, pp. 296-300
-
-
Ishii, T.1
Haga, S.2
-
24
-
-
0001360461
-
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
-
Griffin WS, Stanley LC, Ling C, et al. Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc Natl Acad Sci U S A 1989;86:7611-5.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 7611-7615
-
-
Griffin, W.S.1
Stanley, L.C.2
Ling, C.3
-
25
-
-
0024157709
-
Expression of immune system-associated antigens by cells of the human central nervous system: Relationship to the pathology of Alzheimer's disease
-
Rogers J, Luber-Narod J, Styren SD, Civin WH. Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease. Neurobiol Aging 1988;9:339-49.
-
(1988)
Neurobiol Aging
, vol.9
, pp. 339-349
-
-
Rogers, J.1
Luber-Narod, J.2
Styren, S.D.3
Civin, W.H.4
-
26
-
-
0022504686
-
Role of microglia in plaque formation in senile dementia of the Alzheimer type: An immunohistochemical study
-
Rozemuller JM, Eikelenboom P, Stam FC. Role of microglia in plaque formation in senile dementia of the Alzheimer type: an immunohistochemical study. Virchows Arch B Cell Pathol Incl Mol Pathol 1986;51:247-54.
-
(1986)
Virchows Arch B Cell Pathol Incl Mol Pathol
, vol.51
, pp. 247-254
-
-
Rozemuller, J.M.1
Eikelenboom, P.2
Stam, F.C.3
-
27
-
-
76549104226
-
Neuroinflammation - An early event in both the history and pathogenesis of Alzheimer's disease
-
Eikelenboom P, van Exel E, Hoozemans JJ, Veerhuis R, Rozemuller AJ, van Gool WA. Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer's disease. Neurodegener Dis 2010;7:38-41.
-
(2010)
Neurodegener Dis
, vol.7
, pp. 38-41
-
-
Eikelenboom, P.1
Van Exel, E.2
Hoozemans, J.J.3
Veerhuis, R.4
Rozemuller, A.J.5
Van Gool, W.A.6
-
28
-
-
33644511402
-
Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: Statistical reliability and functional correlation
-
Blalock EM, Chen KC, Stromberg AJ, et al. Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: statistical reliability and functional correlation. Ageing Res Rev 2005;4:481-512.
-
(2005)
Ageing Res Rev
, vol.4
, pp. 481-512
-
-
Blalock, E.M.1
Chen, K.C.2
Stromberg, A.J.3
-
29
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
Lambert JC, Heath S, Even G, et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 2009;41:1094-9.
-
(2009)
Nat Genet
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
-
30
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
Hollingworth P, Harold D, Sims R, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet 2011;43:429-35.
-
(2011)
Nat Genet
, vol.43
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
-
31
-
-
55049142500
-
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE
-
Bertram L, Lange C, Mullin K, et al. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet 2008;83:623-32.
-
(2008)
Am J Hum Genet
, vol.83
, pp. 623-632
-
-
Bertram, L.1
Lange, C.2
Mullin, K.3
-
32
-
-
0034657890
-
Cutting edge: Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes
-
Bouchon A, Dietrich J, Colonna M. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol 2000;164:4991-5.
-
(2000)
J Immunol
, vol.164
, pp. 4991-4995
-
-
Bouchon, A.1
Dietrich, J.2
Colonna, M.3
-
33
-
-
0037805700
-
TREMs in the immune system and beyond
-
Colonna M. TREMs in the immune system and beyond. Nat Rev Immunol 2003;3:445-53.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 445-453
-
-
Colonna, M.1
-
34
-
-
0035887503
-
DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells
-
Bouchon A, Hernández-Munain C, Cella M, Colonna MA. DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells. J Exp Med 2001;194:1111-22.
-
(2001)
J Exp Med
, vol.194
, pp. 1111-1122
-
-
Bouchon, A.1
Hernández-Munain, C.2
Cella, M.3
Colonna, M.A.4
-
35
-
-
67449119394
-
The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor
-
Stefano L, Racchetti G, Bianco F, et al. The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor. J Neurochem 2009;110:284-94.
-
(2009)
J Neurochem
, vol.110
, pp. 284-294
-
-
Stefano, L.1
Racchetti, G.2
Bianco, F.3
-
36
-
-
84855221945
-
TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
-
Ito H, Hamerman JA. TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells. Eur J Immunol 2012;42:176-85.
-
(2012)
Eur J Immunol
, vol.42
, pp. 176-185
-
-
Ito, H.1
Hamerman, J.A.2
-
37
-
-
9644307970
-
Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia
-
Sessa G, Podini P, Mariani M, et al. Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia. Eur J Neurosci 2004;20:2617-28.
-
(2004)
Eur J Neurosci
, vol.20
, pp. 2617-2628
-
-
Sessa, G.1
Podini, P.2
Mariani, M.3
-
38
-
-
33748743268
-
CNS immune privilege: Hiding in plain sight
-
Carson MJ, Doose JM, Melchior B, Schmid CD, Ploix CC. CNS immune privilege: hiding in plain sight. Immunol Rev 2006;213:48-65.
-
(2006)
Immunol Rev
, vol.213
, pp. 48-65
-
-
Carson, M.J.1
Doose, J.M.2
Melchior, B.3
Schmid, C.D.4
Ploix, C.C.5
-
39
-
-
77956238665
-
Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: Implications for vaccine-based therapies for Alzheimer's disease
-
Melchior B, Garcia AE, Hsiung BK, et al. Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease. ASN Neuro 2010;2(3):e00037.
-
(2010)
ASN Neuro
, vol.2
, Issue.3
-
-
Melchior, B.1
Garcia, A.E.2
Hsiung, B.K.3
-
40
-
-
14244268775
-
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
-
Takahashi K, Rochford CD, Neumann H. Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. J Exp Med 2005;201:647-57.
-
(2005)
J Exp Med
, vol.201
, pp. 647-657
-
-
Takahashi, K.1
Rochford, C.D.2
Neumann, H.3
-
41
-
-
33746875981
-
Cutting edge: Inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12
-
Hamerman JA, Jarjoura JR, Humphrey MB, Nakamura MC, Seaman WE, Lanier LL. Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12. J Immunol 2006;177:2051-5.
-
(2006)
J Immunol
, vol.177
, pp. 2051-2055
-
-
Hamerman, J.A.1
Jarjoura, J.R.2
Humphrey, M.B.3
Nakamura, M.C.4
Seaman, W.E.5
Lanier, L.L.6
-
42
-
-
0015443132
-
Neuropsychiatric and genetic aspects of a new hereditary disease characterized by progressive dementia and lipomembranous polycystic osteodysplasia
-
Hakola HP. Neuropsychiatric and genetic aspects of a new hereditary disease characterized by progressive dementia and lipomembranous polycystic osteodysplasia. Acta Psychiatr Scand Suppl 1972;232:1-173.
-
(1972)
Acta Psychiatr Scand Suppl
, vol.232
, pp. 1-173
-
-
Hakola, H.P.1
-
43
-
-
33846050935
-
Nasu-Hakola disease (PLOSL): Report of five cases and review of the literature
-
Madry H, Prudlo J, Grgic A, Freyschmidt J. Nasu-Hakola disease (PLOSL): report of five cases and review of the literature. Clin Orthop Relat Res 2007;454:262-9.
-
(2007)
Clin Orthop Relat Res
, vol.454
, pp. 262-269
-
-
Madry, H.1
Prudlo, J.2
Grgic, A.3
Freyschmidt, J.4
-
44
-
-
0015736566
-
A lipid metabolic disease - "membranous lipodystrophy" - an autopsy case demonstrating numerous peculiar membranestructures composed of compound lipid in bone and bone marrow and various adipose tissues
-
Nasu T, Tsukahara Y, Terayama K. A lipid metabolic disease - "membranous lipodystrophy" - an autopsy case demonstrating numerous peculiar membranestructures composed of compound lipid in bone and bone marrow and various adipose tissues. Acta Pathol Jpn 1973;23:539-58.
-
(1973)
Acta Pathol Jpn
, vol.23
, pp. 539-558
-
-
Nasu, T.1
Tsukahara, Y.2
Terayama, K.3
-
45
-
-
0033945864
-
Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts
-
Paloneva J, Kestilä M, Wu J, et al. Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts. Nat Genet 2000;25:357-61.
-
(2000)
Nat Genet
, vol.25
, pp. 357-361
-
-
Paloneva, J.1
Kestilä, M.2
Wu, J.3
-
46
-
-
18544390923
-
Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype
-
Erratum, Am J Hum Genet 2003;72:225
-
Paloneva J, Manninen T, Christman G, et al. Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype. Am J Hum Genet 2002;71:656-62. [Erratum, Am J Hum Genet 2003;72:225.]
-
(2002)
Am J Hum Genet
, vol.71
, pp. 656-662
-
-
Paloneva, J.1
Manninen, T.2
Christman, G.3
-
47
-
-
73549110158
-
Mutations in TREM2 lead to pure early-onset dementia without bone cysts
-
Chouery E, Delague V, Bergougnoux A, Koussa S, Serre JL, Mégarbané A. Mutations in TREM2 lead to pure early-onset dementia without bone cysts. Hum Mutat 2008;29(9):E194-E204.
-
(2008)
Hum Mutat
, vol.29
, Issue.9
-
-
Chouery, E.1
Delague, V.2
Bergougnoux, A.3
Koussa, S.4
Serre, J.L.5
Mégarbané, A.6
-
48
-
-
84872094776
-
Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement
-
October 8 (Epub ahead of print)
-
Guerreiro RJ, Lohmann E, Brás JM, et al. Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement. Arch Neurol 2012 October 8 (Epub ahead of print).
-
(2012)
Arch Neurol
-
-
Guerreiro, R.J.1
Lohmann, E.2
Brás, J.M.3
-
49
-
-
20444378116
-
Neuropsychological tests and functional nuclear neuroimaging provide evidence of subclinical impairment in Nasu-Hakola disease heterozygotes
-
Montalbetti L, Ratti MT, Greco B, Aprile C, Moglia A, Soragna D. Neuropsychological tests and functional nuclear neuroimaging provide evidence of subclinical impairment in Nasu-Hakola disease heterozygotes. Funct Neurol 2005;20:71-5.
-
(2005)
Funct Neurol
, vol.20
, pp. 71-75
-
-
Montalbetti, L.1
Ratti, M.T.2
Greco, B.3
Aprile, C.4
Moglia, A.5
Soragna, D.6
|