-
1
-
-
0035949487
-
Presenilin, Notch, and the genesis and treatment of Alzheimer's disease
-
Selkoe DJ (2001) Presenilin, Notch, and the genesis and treatment of Alzheimer's disease. Proc Natl Acad Sci USA 98: 11039-11041.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11039-11041
-
-
Selkoe, D.J.1
-
2
-
-
44949185340
-
A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics
-
Rosenmann H, Grigoriadis N, Eldar-Levy H, Avital A, Rozenstein L, et al. (2008) A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics. Exp Neurol 212: 71-84.
-
(2008)
Exp Neurol
, vol.212
, pp. 71-84
-
-
Rosenmann, H.1
Grigoriadis, N.2
Eldar-Levy, H.3
Avital, A.4
Rozenstein, L.5
-
3
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, et al. (2008) Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med.
-
(2008)
Nat Med
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
-
4
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, et al. (2000) Inflammation and Alzheimer's disease. Neurobiol Aging 21: 383-421.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
Bradt, B.4
Bauer, J.5
-
5
-
-
0005966256
-
T-cell responses to myelin antigens in multiple sclerosis; relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycoprotein
-
de Rosbo NK, Ben-Nun A (1998) T-cell responses to myelin antigens in multiple sclerosis; relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycoprotein. J Autoimmun 11: 287-299.
-
(1998)
J Autoimmun
, vol.11
, pp. 287-299
-
-
de Rosbo, N.K.1
Ben-Nun, A.2
-
6
-
-
0034724441
-
Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor
-
Waldner H, Whitters MJ, Sobel RA, Collins M, Kuchroo VK (2000) Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. Proc Natl Acad Sci USA 97: 3412-3417.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3412-3417
-
-
Waldner, H.1
Whitters, M.J.2
Sobel, R.A.3
Collins, M.4
Kuchroo, V.K.5
-
7
-
-
16244380177
-
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
-
Greter M, Heppner FL, Lemos MP, Odermatt BM, Goebels N, et al. (2005) Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat Med 11: 328-334.
-
(2005)
Nat Med
, vol.11
, pp. 328-334
-
-
Greter, M.1
Heppner, F.L.2
Lemos, M.P.3
Odermatt, B.M.4
Goebels, N.5
-
8
-
-
33644836341
-
Mechanisms of immunopathology in murine models of central nervous system demyelinating disease
-
Ercolini AM, Miller SD (2006) Mechanisms of immunopathology in murine models of central nervous system demyelinating disease. J Immunol 176: 3293-3298.
-
(2006)
J Immunol
, vol.176
, pp. 3293-3298
-
-
Ercolini, A.M.1
Miller, S.D.2
-
9
-
-
67349207476
-
Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis
-
Krishnamoorthy G, Saxena A, Mars LT, Domingues HS, Mentele R, et al. (2009) Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. Nat Med 15: 626-632.
-
(2009)
Nat Med
, vol.15
, pp. 626-632
-
-
Krishnamoorthy, G.1
Saxena, A.2
Mars, L.T.3
Domingues, H.S.4
Mentele, R.5
-
10
-
-
24644435506
-
Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease
-
Frenkel D, Maron R, Burt DS, Weiner HL (2005) Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease. J Clin Invest 115: 2423-2433.
-
(2005)
J Clin Invest
, vol.115
, pp. 2423-2433
-
-
Frenkel, D.1
Maron, R.2
Burt, D.S.3
Weiner, H.L.4
-
11
-
-
33746827434
-
Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1
-
Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, et al. (2006) Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1. Proc Natl Acad Sci USA 103: 11784-11789.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11784-11789
-
-
Butovsky, O.1
Koronyo-Hamaoui, M.2
Kunis, G.3
Ophir, E.4
Landa, G.5
-
12
-
-
0034279106
-
Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion
-
Hauben E, Butovsky O, Nevo U, Yoles E, Moalem G, et al. (2000) Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion. J Neurosci 20: 6421-6430.
-
(2000)
J Neurosci
, vol.20
, pp. 6421-6430
-
-
Hauben, E.1
Butovsky, O.2
Nevo, U.3
Yoles, E.4
Moalem, G.5
-
13
-
-
0033049143
-
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
-
Moalem G, Leibowitz-Amit R, Yoles E, Mor F, Cohen IR, et al. (1999) Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nat Med 5: 49-55.
-
(1999)
Nat Med
, vol.5
, pp. 49-55
-
-
Moalem, G.1
Leibowitz-Amit, R.2
Yoles, E.3
Mor, F.4
Cohen, I.R.5
-
14
-
-
41149088328
-
T cells in amyotrophic lateral sclerosis
-
Holmoy T (2008) T cells in amyotrophic lateral sclerosis. Eur J Neurol 15: 360-366.
-
(2008)
Eur J Neurol
, vol.15
, pp. 360-366
-
-
Holmoy, T.1
-
15
-
-
0346366987
-
Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells
-
Frenkel D, Huang Z, Maron R, Koldzic DN, Hancock WW, et al. (2003) Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells. J Immunol 171: 6549-6555.
-
(2003)
J Immunol
, vol.171
, pp. 6549-6555
-
-
Frenkel, D.1
Huang, Z.2
Maron, R.3
Koldzic, D.N.4
Hancock, W.W.5
-
16
-
-
33645517069
-
Abeta-induced meningoencephalitis is IFN-{gamma}-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease
-
Monsonego A, Imitola J, Petrovic S, Zota V, Nemirovsky A, et al. (2006) Abeta-induced meningoencephalitis is IFN-{gamma}-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 103: 5048-5053.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5048-5053
-
-
Monsonego, A.1
Imitola, J.2
Petrovic, S.3
Zota, V.4
Nemirovsky, A.5
-
17
-
-
20444371569
-
Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke
-
Frenkel D, Huang Z, Maron R, Koldzic DN, Moskowitz MA, et al. (2005) Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke. J Neurol Sci 233: 125-132.
-
(2005)
J Neurol Sci
, vol.233
, pp. 125-132
-
-
Frenkel, D.1
Huang, Z.2
Maron, R.3
Koldzic, D.N.4
Moskowitz, M.A.5
-
18
-
-
24744435759
-
Neurogenesis and neuroprotection induced by peripheral immunomodulatory treatment of experimental autoimmune encephalomyelitis
-
Aharoni R, Arnon R, Eilam R (2005) Neurogenesis and neuroprotection induced by peripheral immunomodulatory treatment of experimental autoimmune encephalomyelitis. J Neurosci 25: 8217-8228.
-
(2005)
J Neurosci
, vol.25
, pp. 8217-8228
-
-
Aharoni, R.1
Arnon, R.2
Eilam, R.3
-
19
-
-
33646791175
-
The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis
-
Hohlfeld R, Kerschensteiner M, Stadelmann C, Lassmann H, Wekerle H (2006) The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis. Neurol Sci 27 Suppl 1: S1-7.
-
(2006)
Neurol Sci 27
, vol.27
, Issue.SUPPL. 1
-
-
Hohlfeld, R.1
Kerschensteiner, M.2
Stadelmann, C.3
Lassmann, H.4
Wekerle, H.5
-
20
-
-
14844309321
-
Protective autoimmunity: Interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators
-
Shaked I, Tchoresh D, Gersner R, Meiri G, Mordechai S, et al. (2005) Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators. J Neurochem 92: 997-1009.
-
(2005)
J Neurochem
, vol.92
, pp. 997-1009
-
-
Shaked, I.1
Tchoresh, D.2
Gersner, R.3
Meiri, G.4
Mordechai, S.5
-
21
-
-
31544460682
-
Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood
-
Ziv Y, Ron N, Butovsky O, Landa G, Sudai E, et al. (2006) Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood. Nat Neurosci 9: 268-275.
-
(2006)
Nat Neurosci
, vol.9
, pp. 268-275
-
-
Ziv, Y.1
Ron, N.2
Butovsky, O.3
Landa, G.4
Sudai, E.5
-
22
-
-
48749086244
-
IFN-{gamma} enhances neurogenesis in wild-type mice and in a mouse model of Alzheimer's disease
-
Baron R, Nemirovsky A, Harpaz I, Cohen H, Owens T, et al. (2008) IFN-{gamma} enhances neurogenesis in wild-type mice and in a mouse model of Alzheimer's disease. Faseb J.
-
(2008)
Faseb J
-
-
Baron, R.1
Nemirovsky, A.2
Harpaz, I.3
Cohen, H.4
Owens, T.5
-
23
-
-
64249134817
-
CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis
-
Wolf SA, Steiner B, Akpinarli A, Kammertoens T, Nassenstein C, et al. (2009) CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis. J Immunol 182: 3979-3984.
-
(2009)
J Immunol
, vol.182
, pp. 3979-3984
-
-
Wolf, S.A.1
Steiner, B.2
Akpinarli, A.3
Kammertoens, T.4
Nassenstein, C.5
-
24
-
-
73649129558
-
Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice
-
Mastrangelo MA, Sudol KL, Narrow WC, Bowers WJ (2009) Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice. Am J Pathol 175: 2076-2088.
-
(2009)
Am J Pathol
, vol.175
, pp. 2076-2088
-
-
Mastrangelo, M.A.1
Sudol, K.L.2
Narrow, W.C.3
Bowers, W.J.4
-
25
-
-
0041886776
-
Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease
-
Monsonego A, Zota V, Karni A, Krieger JI, Bar-Or A, et al. (2003) Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease. J Clin Invest 112: 415-422.
-
(2003)
J Clin Invest
, vol.112
, pp. 415-422
-
-
Monsonego, A.1
Zota, V.2
Karni, A.3
Krieger, J.I.4
Bar-Or, A.5
-
26
-
-
70349249522
-
HLA-DR alleles in amyloid beta-peptide autoimmunity: A highly immunogenic role for the DRB1*1501 allele
-
Zota V, Nemirovsky A, Baron R, Fisher Y, Selkoe DJ, et al. (2009) HLA-DR alleles in amyloid beta-peptide autoimmunity: a highly immunogenic role for the DRB1*1501 allele. J Immunol 183: 3522-3530.
-
(2009)
J Immunol
, vol.183
, pp. 3522-3530
-
-
Zota, V.1
Nemirovsky, A.2
Baron, R.3
Fisher, Y.4
Selkoe, D.J.5
-
27
-
-
0035152836
-
Immune function of microglia
-
Aloisi F (2001) Immune function of microglia. Glia 36: 165-179.
-
(2001)
Glia
, vol.36
, pp. 165-179
-
-
Aloisi, F.1
-
28
-
-
0034162486
-
IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines
-
Tran EH, Prince EN, Owens T (2000) IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines. J Immunol 164: 2759-2768.
-
(2000)
J Immunol
, vol.164
, pp. 2759-2768
-
-
Tran, E.H.1
Prince, E.N.2
Owens, T.3
-
29
-
-
84879796333
-
-
Frank MG, Barrientos RM, Biedenkapp JC, Rudy JW, Watkins LR, et al. (2005) mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging. Neurobiol Aging.
-
(2005)
MRNA Up-regulation of MHC II and Pivotal Pro-inflammatory Genes In Normal Brain Aging. Neurobiol Aging
-
-
Frank, M.G.1
Barrientos, R.M.2
Biedenkapp, J.C.3
Rudy, J.W.4
Watkins, L.R.5
-
30
-
-
20444364844
-
Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective
-
Butovsky O, Talpalar AE, Ben-Yaakov K, Schwartz M (2005) Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective. Mol Cell Neurosci 29: 381-393.
-
(2005)
Mol Cell Neurosci
, vol.29
, pp. 381-393
-
-
Butovsky, O.1
Talpalar, A.E.2
Ben-Yaakov, K.3
Schwartz, M.4
-
31
-
-
31544477648
-
Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells
-
Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, et al. (2005) Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol Cell Neurosci.
-
(2005)
Mol Cell Neurosci
-
-
Butovsky, O.1
Ziv, Y.2
Schwartz, A.3
Landa, G.4
Talpalar, A.E.5
-
32
-
-
23444449846
-
Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation
-
Kwidzinski E, Bunse J, Aktas O, Richter D, Mutlu L, et al. (2005) Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation. Faseb J 19: 1347-1349.
-
(2005)
Faseb J
, vol.19
, pp. 1347-1349
-
-
Kwidzinski, E.1
Bunse, J.2
Aktas, O.3
Richter, D.4
Mutlu, L.5
-
33
-
-
33744934491
-
Interferon-gamma is up-regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity
-
Lee J, Kim SJ, Son TG, Chan SL, Mattson MP (2006) Interferon-gamma is up-regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity. J Neurosci Res 83: 1552-1557.
-
(2006)
J Neurosci Res
, vol.83
, pp. 1552-1557
-
-
Lee, J.1
Kim, S.J.2
Son, T.G.3
Chan, S.L.4
Mattson, M.P.5
-
34
-
-
33746095375
-
Elevated interferon gamma expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis
-
Wheeler RD, Zehntner SP, Kelly LM, Bourbonniere L, Owens T (2006) Elevated interferon gamma expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis. Immunology 118: 527-538.
-
(2006)
Immunology
, vol.118
, pp. 527-538
-
-
Wheeler, R.D.1
Zehntner, S.P.2
Kelly, L.M.3
Bourbonniere, L.4
Owens, T.5
-
35
-
-
0032419459
-
Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE
-
Renno T, Taupin V, Bourbonniere L, Verge G, Tran E, et al. (1998) Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE. Mol Cell Neurosci 12: 376-389.
-
(1998)
Mol Cell Neurosci
, vol.12
, pp. 376-389
-
-
Renno, T.1
Taupin, V.2
Bourbonniere, L.3
Verge, G.4
Tran, E.5
-
36
-
-
0034213718
-
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
-
Mucke L, Masliah E, Yu GQ, Mallory M, Rockenstein EM, et al. (2000) High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J Neurosci 20: 4050-4058.
-
(2000)
J Neurosci
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
-
37
-
-
33748988258
-
Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
-
Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, et al. (2006) Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep 7: 940-946.
-
(2006)
EMBO Rep
, vol.7
, pp. 940-946
-
-
Radde, R.1
Bolmont, T.2
Kaeser, S.A.3
Coomaraswamy, J.4
Lindau, D.5
-
38
-
-
58149129243
-
Consequence of A{beta} immunization on the vasculature of human Alzheimer's disease brain
-
Boche D, Zotova E, Weller RO, Love S, Neal JW, et al. (2008) Consequence of A{beta} immunization on the vasculature of human Alzheimer's disease brain. Brain.
-
(2008)
Brain
-
-
Boche, D.1
Zotova, E.2
Weller, R.O.3
Love, S.4
Neal, J.W.5
-
39
-
-
47149112621
-
Long-term effects of Abeta42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebo-controlled phase I trial
-
Holmes C, Boche D, Wilkinson D, Yadegarfar G, Hopkins V, et al. (2008) Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet 372: 216-223.
-
(2008)
Lancet
, vol.372
, pp. 216-223
-
-
Holmes, C.1
Boche, D.2
Wilkinson, D.3
Yadegarfar, G.4
Hopkins, V.5
-
40
-
-
14244268775
-
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
-
Takahashi K, Rochford CD, Neumann H (2005) Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. J Exp Med 201: 647-657.
-
(2005)
J Exp Med
, vol.201
, pp. 647-657
-
-
Takahashi, K.1
Rochford, C.D.2
Neumann, H.3
-
41
-
-
73549091923
-
Signal regulatory protein-beta1: A microglial modulator of phagocytosis in Alzheimer's disease
-
Gaikwad S, Larionov S, Wang Y, Dannenberg H, Matozaki T, et al. (2009) Signal regulatory protein-beta1: a microglial modulator of phagocytosis in Alzheimer's disease. Am J Pathol 175: 2528-2539.
-
(2009)
Am J Pathol
, vol.175
, pp. 2528-2539
-
-
Gaikwad, S.1
Larionov, S.2
Wang, Y.3
Dannenberg, H.4
Matozaki, T.5
-
42
-
-
33745631754
-
Antigen presentation in autoimmunity and CNS inflammation: How T lymphocytes recognize the brain
-
Becher B, Bechmann I, Greter M (2006) Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain. J Mol Med 84: 532-543.
-
(2006)
J Mol Med
, vol.84
, pp. 532-543
-
-
Becher, B.1
Bechmann, I.2
Greter, M.3
-
43
-
-
0035071610
-
Turnover of rat brain perivascular cells
-
Bechmann I, Kwidzinski E, Kovac AD, Simburger E, Horvath T, et al. (2001) Turnover of rat brain perivascular cells. Exp Neurol 168: 242-249.
-
(2001)
Exp Neurol
, vol.168
, pp. 242-249
-
-
Bechmann, I.1
Kwidzinski, E.2
Kovac, A.D.3
Simburger, E.4
Horvath, T.5
-
44
-
-
0035152834
-
Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system
-
Williams K, Alvarez X, Lackner AA (2001) Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system. Glia 36: 156-164.
-
(2001)
Glia
, vol.36
, pp. 156-164
-
-
Williams, K.1
Alvarez, X.2
Lackner, A.A.3
-
45
-
-
4344648449
-
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis
-
Herzig MC, Winkler DT, Burgermeister P, Pfeifer M, Kohler E, et al. (2004) Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis. Nat Neurosci 7: 954-960.
-
(2004)
Nat Neurosci
, vol.7
, pp. 954-960
-
-
Herzig, M.C.1
Winkler, D.T.2
Burgermeister, P.3
Pfeifer, M.4
Kohler, E.5
-
46
-
-
0034744296
-
TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice
-
Wyss-Coray T, Lin C, Yan F, Yu GQ, Rohde M, et al. (2001) TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nat Med 7: 612-618.
-
(2001)
Nat Med
, vol.7
, pp. 612-618
-
-
Wyss-Coray, T.1
Lin, C.2
Yan, F.3
Yu, G.Q.4
Rohde, M.5
-
47
-
-
33750953844
-
Increased T cell recruitment to the CNS after amyloid beta 1-42 immunization in Alzheimer's mice overproducing transforming growth factor-beta 1
-
Buckwalter MS, Coleman BS, Buttini M, Barbour R, Schenk D, et al. (2006) Increased T cell recruitment to the CNS after amyloid beta 1-42 immunization in Alzheimer's mice overproducing transforming growth factor-beta 1. J Neurosci 26: 11437-11441.
-
(2006)
J Neurosci
, vol.26
, pp. 11437-11441
-
-
Buckwalter, M.S.1
Coleman, B.S.2
Buttini, M.3
Barbour, R.4
Schenk, D.5
-
48
-
-
0034982596
-
Immunological update on multiple sclerosis
-
Hohlfeld R, Wekerle H (2001) Immunological update on multiple sclerosis. Curr Opin Neurol 14: 299-304.
-
(2001)
Curr Opin Neurol
, vol.14
, pp. 299-304
-
-
Hohlfeld, R.1
Wekerle, H.2
-
49
-
-
34548434392
-
Chronic interleukin-1beta expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood brain barrier permeability without overt neurodegeneration
-
Shaftel SS, Carlson TJ, Olschowka JA, Kyrkanides S, Matousek SB, et al. (2007) Chronic interleukin-1beta expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood brain barrier permeability without overt neurodegeneration. J Neurosci 27: 9301-9309.
-
(2007)
J Neurosci
, vol.27
, pp. 9301-9309
-
-
Shaftel, S.S.1
Carlson, T.J.2
Olschowka, J.A.3
Kyrkanides, S.4
Matousek, S.B.5
-
50
-
-
0035400122
-
Neuronal survival after CNS insult is determined by a genetically encoded autoimmune response
-
Kipnis J, Yoles E, Schori H, Hauben E, Shaked I, et al. (2001) Neuronal survival after CNS insult is determined by a genetically encoded autoimmune response. J Neurosci 21: 4564-4571.
-
(2001)
J Neurosci
, vol.21
, pp. 4564-4571
-
-
Kipnis, J.1
Yoles, E.2
Schori, H.3
Hauben, E.4
Shaked, I.5
-
51
-
-
0034633632
-
Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administration
-
Frenkel D, Katz O, Solomon B (2000) Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administration. Proc Natl Acad Sci USA 97: 11455-11459.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11455-11459
-
-
Frenkel, D.1
Katz, O.2
Solomon, B.3
-
52
-
-
0034700471
-
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus C, Pearson J, McLaurin J, Mathews PM, Jiang Y, et al. (2000) A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 408: 979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
-
53
-
-
33646938005
-
Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response
-
Maier M, Seabrook TJ, Lazo ND, Jiang L, Das P, et al. (2006) Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response. J Neurosci 26: 4717-4728.
-
(2006)
J Neurosci
, vol.26
, pp. 4717-4728
-
-
Maier, M.1
Seabrook, T.J.2
Lazo, N.D.3
Jiang, L.4
Das, P.5
-
54
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, et al. (2000) A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408: 982-985.
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
-
55
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse [see comments]
-
Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, et al. (1999) Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse [see comments]. Nature 400: 173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
-
56
-
-
0033801852
-
Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease
-
Weiner HL, Lemere CA, Maron R, Spooner ET, Grenfell TJ, et al. (2000) Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease. Ann Neurol 48: 567-579.
-
(2000)
Ann Neurol
, vol.48
, pp. 567-579
-
-
Weiner, H.L.1
Lemere, C.A.2
Maron, R.3
Spooner, E.T.4
Grenfell, T.J.5
-
57
-
-
33847223756
-
Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis
-
Balabanov R, Strand K, Goswami R, McMahon E, Begolka W, et al. (2007) Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis. J Neurosci 27: 2013-2024.
-
(2007)
J Neurosci
, vol.27
, pp. 2013-2024
-
-
Balabanov, R.1
Strand, K.2
Goswami, R.3
McMahon, E.4
Begolka, W.5
-
58
-
-
0033759283
-
Interferon-gamma protects against cuprizone-induced demyelination
-
Gao X, Gillig TA, Ye P, D'Ercole AJ, Matsushima GK, et al. (2000) Interferon-gamma protects against cuprizone-induced demyelination. Mol Cell Neurosci 16: 338-349.
-
(2000)
Mol Cell Neurosci
, vol.16
, pp. 338-349
-
-
Gao, X.1
Gillig, T.A.2
Ye, P.3
D'ercole, A.J.4
Matsushima, G.K.5
-
59
-
-
10744230547
-
Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
-
Orgogozo JM, Gilman S, Dartigues JF, Laurent B, Puel M, et al. (2003) Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology 61: 46-54.
-
(2003)
Neurology
, vol.61
, pp. 46-54
-
-
Orgogozo, J.M.1
Gilman, S.2
Dartigues, J.F.3
Laurent, B.4
Puel, M.5
-
60
-
-
40449089827
-
Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
-
Stromnes IM, Cerretti LM, Liggitt D, Harris RA, Goverman JM (2008) Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat Med 14: 337-342.
-
(2008)
Nat Med
, vol.14
, pp. 337-342
-
-
Stromnes, I.M.1
Cerretti, L.M.2
Liggitt, D.3
Harris, R.A.4
Goverman, J.M.5
-
61
-
-
0037112201
-
Cerebral hemorrhage after passive anti-Abeta immunotherapy
-
Pfeifer M, Boncristiano S, Bondolfi L, Stalder A, Deller T, et al. (2002) Cerebral hemorrhage after passive anti-Abeta immunotherapy. Science 298: 1379.
-
(2002)
Science
, vol.298
, pp. 1379
-
-
Pfeifer, M.1
Boncristiano, S.2
Bondolfi, L.3
Stalder, A.4
Deller, T.5
-
62
-
-
33745509314
-
Vessel ultrastructure in APP23 transgenic mice after passive anti-Abeta immunotherapy and subsequent intracerebral hemorrhage
-
Burbach GJ, Vlachos A, Ghebremedhin E, Turco DD, Coomaraswamy J, et al. (2006) Vessel ultrastructure in APP23 transgenic mice after passive anti-Abeta immunotherapy and subsequent intracerebral hemorrhage. Neurobiol Aging.
-
(2006)
Neurobiol Aging
-
-
Burbach, G.J.1
Vlachos, A.2
Ghebremedhin, E.3
Turco, D.D.4
Coomaraswamy, J.5
-
63
-
-
19944431509
-
Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta
-
Racke MM, Boone LI, Hepburn DL, Parsadainian M, Bryan MT, et al. (2005) Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta. J Neurosci 25: 629-636.
-
(2005)
J Neurosci
, vol.25
, pp. 629-636
-
-
Racke, M.M.1
Boone, L.I.2
Hepburn, D.L.3
Parsadainian, M.4
Bryan, M.T.5
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