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Volumn 32, Issue 10, 2007, Pages 1799-1807

Role of cell cycle proteins in CNS injury

Author keywords

Brain injury; Flavopiridol; Proliferation; Review; Spinal cord injury; Stroke

Indexed keywords

FLAVOPIRIDOL; OLOMOUCINE; ROSCOVITINE;

EID: 34548804568     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-007-9312-2     Document Type: Review
Times cited : (86)

References (79)
  • 1
    • 25444457320 scopus 로고    scopus 로고
    • Role of the cell cycle in the pathobiology of central nervous system trauma
    • Cernak I, Stoica B, Byrnes KR et al (2005) Role of the cell cycle in the pathobiology of central nervous system trauma. Cell Cycle 4:1286-1293
    • (2005) Cell Cycle , vol.4 , pp. 1286-1293
    • Cernak, I.1    Stoica, B.2    Byrnes, K.R.3
  • 2
    • 0037379603 scopus 로고    scopus 로고
    • Gene profiling in spinal cord injury shows role of cell cycle in neuronal death
    • Di Giovanni S, Knoblach SM, Brandoli C et al (2003) Gene profiling in spinal cord injury shows role of cell cycle in neuronal death. Ann Neurol 53:454-468
    • (2003) Ann Neurol , vol.53 , pp. 454-468
    • Di Giovanni, S.1    Knoblach, S.M.2    Brandoli, C.3
  • 3
    • 1642433100 scopus 로고    scopus 로고
    • Cell cycle molecules and vertebrate neuron death: E2F at the hub
    • Greene LA, Biswas SC, Liu DX (2004) Cell cycle molecules and vertebrate neuron death: E2F at the hub. Cell Death Differ 11:49-60
    • (2004) Cell Death Differ , vol.11 , pp. 49-60
    • Greene, L.A.1    Biswas, S.C.2    Liu, D.X.3
  • 4
    • 0032736977 scopus 로고    scopus 로고
    • DNA fragmentation precedes aberrant expression of cell cycle-related protein in rat brain after MCA occlusion
    • Hayashi T, Sakurai M, Abe K et al (1999) DNA fragmentation precedes aberrant expression of cell cycle-related protein in rat brain after MCA occlusion. Neurol Res 21:695-698
    • (1999) Neurol Res , vol.21 , pp. 695-698
    • Hayashi, T.1    Sakurai, M.2    Abe, K.3
  • 5
    • 0038400000 scopus 로고    scopus 로고
    • Cell cycle protein expression in proliferating microglia and astrocytes following transient global cerebral ischemia in the rat
    • Kato H, Takahashi A, Itoyama Y (2003) Cell cycle protein expression in proliferating microglia and astrocytes following transient global cerebral ischemia in the rat. Brain Res Bull 60:215-221
    • (2003) Brain Res Bull , vol.60 , pp. 215-221
    • Kato, H.1    Takahashi, A.2    Itoyama, Y.3
  • 6
    • 0033528230 scopus 로고    scopus 로고
    • Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain
    • Kaya SS, Mahmood A, Li Y et al (1999) Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain. Brain Res 818:23-33
    • (1999) Brain Res , vol.818 , pp. 23-33
    • Kaya, S.S.1    Mahmood, A.2    Li, Y.3
  • 7
    • 0033570320 scopus 로고    scopus 로고
    • Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis
    • Padmanabhan J, Park DS, Greene LA et al (1999) Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. J Neurosci 19:8747-8756
    • (1999) J Neurosci , vol.19 , pp. 8747-8756
    • Padmanabhan, J.1    Park, D.S.2    Greene, L.A.3
  • 8
    • 3142779071 scopus 로고    scopus 로고
    • Activation of cell cycle regulatory proteins in the apoptosis of terminally differentiated oligodendrocytes
    • Strazza M, Luddi A, Brogi A et al (2004) Activation of cell cycle regulatory proteins in the apoptosis of terminally differentiated oligodendrocytes. Neurochem Res 29:923-931
    • (2004) Neurochem Res , vol.29 , pp. 923-931
    • Strazza, M.1    Luddi, A.2    Brogi, A.3
  • 9
    • 0029922376 scopus 로고    scopus 로고
    • Cyclin D1 messenger RNA is induced in microglia rather than neurons following transient forebrain ischaemia
    • Wiessner C, Brink I, Lorenz P et al (1996) Cyclin D1 messenger RNA is induced in microglia rather than neurons following transient forebrain ischaemia. Neuroscience 72:947-958
    • (1996) Neuroscience , vol.72 , pp. 947-958
    • Wiessner, C.1    Brink, I.2    Lorenz, P.3
  • 10
    • 20444427615 scopus 로고    scopus 로고
    • Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury
    • Di Giovanni S, Movsesyan V, Ahmed F et al (2005) Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury. Proc Natl Acad Sci USA 102:8333-8338
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8333-8338
    • Di Giovanni, S.1    Movsesyan, V.2    Ahmed, F.3
  • 11
    • 1642538995 scopus 로고    scopus 로고
    • Inhibition of cell cycle pathway by flavopiridol promotes survival of cerebellar granule cells after an excitotoxic treatment
    • Verdaguer E, Jimenez A, Canudas AM et al (2004) Inhibition of cell cycle pathway by flavopiridol promotes survival of cerebellar granule cells after an excitotoxic treatment. J Pharmacol Exp Ther 308:609-616
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 609-616
    • Verdaguer, E.1    Jimenez, A.2    Canudas, A.M.3
  • 12
    • 0036167643 scopus 로고    scopus 로고
    • Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat
    • Wang F, Corbett D, Osuga H et al (2002) Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat. J Cereb Blood Flow Metab 22:171-182
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 171-182
    • Wang, F.1    Corbett, D.2    Osuga, H.3
  • 13
    • 1342333775 scopus 로고    scopus 로고
    • Cell cycle activation linked to neuronal cell death initiated by DNA damage
    • Kruman II, Wersto RP, Cardozo-Pelaez F et al (2004) Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron 41:549-561
    • (2004) Neuron , vol.41 , pp. 549-561
    • Kruman, I.I.1    Wersto, R.P.2    Cardozo-Pelaez, F.3
  • 14
    • 3042835140 scopus 로고    scopus 로고
    • Roles of cyclin-dependent kinase 4 and p53 in neuronal cell death induced by doxorubicin on cerebellar granule neurons in mouse
    • Otsuka Y, Tanaka T, Uchida D et al (2004) Roles of cyclin-dependent kinase 4 and p53 in neuronal cell death induced by doxorubicin on cerebellar granule neurons in mouse. Neurosci Lett 365:180-185
    • (2004) Neurosci Lett , vol.365 , pp. 180-185
    • Otsuka, Y.1    Tanaka, T.2    Uchida, D.3
  • 15
    • 0033636761 scopus 로고    scopus 로고
    • Cell cycle regulators in neuronal death evoked by excitotoxic stress: Implications for neurodegeneration and its treatment
    • Park DS, Obeidat A, Giovanni A et al (2000) Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment. Neurobiol Aging 21:771-781
    • (2000) Neurobiol Aging , vol.21 , pp. 771-781
    • Park, D.S.1    Obeidat, A.2    Giovanni, A.3
  • 16
    • 2542428253 scopus 로고    scopus 로고
    • Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats
    • Wen Y, Yang S, Liu R et al (2004) Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats. J Biol Chem 279:22684-22692
    • (2004) J Biol Chem , vol.279 , pp. 22684-22692
    • Wen, Y.1    Yang, S.2    Liu, R.3
  • 18
    • 0027174606 scopus 로고
    • RB and Cdc2 expression in brain: Correlations with 3H-thymidine incorporation and neurogenesis
    • Okano HJ, Pfaff DW, Gibbs RB (1993) RB and Cdc2 expression in brain: correlations with 3H-thymidine incorporation and neurogenesis. J Neurosci 13:2930-2938
    • (1993) J Neurosci , vol.13 , pp. 2930-2938
    • Okano, H.J.1    Pfaff, D.W.2    Gibbs, R.B.3
  • 19
    • 12244303616 scopus 로고    scopus 로고
    • Cycling at the interface between neurodevelopment and neurodegeneration
    • Nguyen MD, Mushynski WE, Julien JP (2002) Cycling at the interface between neurodevelopment and neurodegeneration. Cell Death Differ 9:1294-1306
    • (2002) Cell Death Differ , vol.9 , pp. 1294-1306
    • Nguyen, M.D.1    Mushynski, W.E.2    Julien, J.P.3
  • 20
    • 0036469268 scopus 로고    scopus 로고
    • N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons
    • Wartiovaara K, Barnabe-Heider F, Miller FD et al (2002) N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons. J Neurosci 22:815-824
    • (2002) J Neurosci , vol.22 , pp. 815-824
    • Wartiovaara, K.1    Barnabe-Heider, F.2    Miller, F.D.3
  • 21
    • 0141640830 scopus 로고    scopus 로고
    • Progression through the G1-phase of the on-going cell cycle
    • Boonstra J (2003) Progression through the G1-phase of the on-going cell cycle. J Cell Biochem 90:244-252
    • (2003) J Cell Biochem , vol.90 , pp. 244-252
    • Boonstra, J.1
  • 22
    • 0027336491 scopus 로고
    • Mammalian G1 cyclins
    • Sherr CJ (1993) Mammalian G1 cyclins. Cell 73:1059-1065
    • (1993) Cell , vol.73 , pp. 1059-1065
    • Sherr, C.J.1
  • 23
    • 0035998262 scopus 로고    scopus 로고
    • Control of DNA replication licensing in a cell cycle
    • Nishitani H, Lygerou Z (2002) Control of DNA replication licensing in a cell cycle. Genes Cells 7:523-534
    • (2002) Genes Cells , vol.7 , pp. 523-534
    • Nishitani, H.1    Lygerou, Z.2
  • 24
    • 0036163745 scopus 로고    scopus 로고
    • Regulation of cyclin-Cdk activity in mammalian cells
    • Obaya AJ, Sedivy JM (2002) Regulation of cyclin-Cdk activity in mammalian cells. Cell Mol Life Sci 59:126-142
    • (2002) Cell Mol Life Sci , vol.59 , pp. 126-142
    • Obaya, A.J.1    Sedivy, J.M.2
  • 26
    • 0037304898 scopus 로고    scopus 로고
    • New roles for p21 and p27 cell-cycle inhibitors: A function for each cell compartment?
    • Coqueret O (2003) New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol 13:65-70
    • (2003) Trends Cell Biol , vol.13 , pp. 65-70
    • Coqueret, O.1
  • 27
    • 0029330474 scopus 로고
    • Mammalian G1 cyclins and cell cycle progression
    • Sherr CJ (1995) Mammalian G1 cyclins and cell cycle progression. Proc Assoc Am Physicians 107:181-186
    • (1995) Proc Assoc Am Physicians , vol.107 , pp. 181-186
    • Sherr, C.J.1
  • 28
    • 12644284504 scopus 로고    scopus 로고
    • The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2
    • Kitagawa M, Higashi H, Jung HK et al (1996) The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2. Embo J 15:7060-7069
    • (1996) Embo J , vol.15 , pp. 7060-7069
    • Kitagawa, M.1    Higashi, H.2    Jung, H.K.3
  • 29
    • 0035829650 scopus 로고    scopus 로고
    • Regulation of neuronal survival and death by E2F-dependent gene repression and derepression
    • Liu DX, Greene LA (2001) Regulation of neuronal survival and death by E2F-dependent gene repression and derepression. Neuron 32:425-438
    • (2001) Neuron , vol.32 , pp. 425-438
    • Liu, D.X.1    Greene, L.A.2
  • 30
    • 0037023755 scopus 로고    scopus 로고
    • Signaling networks that link cell proliferation and cell fate
    • Sears RC, Nevins JR (2002) Signaling networks that link cell proliferation and cell fate. J Biol Chem 277:11617-11620
    • (2002) J Biol Chem , vol.277 , pp. 11617-11620
    • Sears, R.C.1    Nevins, J.R.2
  • 31
    • 0034730122 scopus 로고    scopus 로고
    • Cyclin-dependent kinases as a therapeutic target for stroke
    • Osuga H, Osuga S, Wang F et al (2000) Cyclin-dependent kinases as a therapeutic target for stroke. Proc Natl Acad Sci USA 97:10254-10259
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10254-10259
    • Osuga, H.1    Osuga, S.2    Wang, F.3
  • 32
    • 0027522370 scopus 로고
    • Temporal regulation of cyclin A-p107 and p33cdk2 complexes binding to a human thymidine kinase promoter element important for G1-S phase transcriptional regulation
    • Li LJ, Naeve GS, Lee AS (1993) Temporal regulation of cyclin A-p107 and p33cdk2 complexes binding to a human thymidine kinase promoter element important for G1-S phase transcriptional regulation. Proc Natl Acad Sci USA 90:3554-3558
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3554-3558
    • Li, L.J.1    Naeve, G.S.2    Lee, A.S.3
  • 33
    • 0030061451 scopus 로고    scopus 로고
    • Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity
    • Guadagno TM, Newport JW (1996) Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity. Cell 84:73-82
    • (1996) Cell , vol.84 , pp. 73-82
    • Guadagno, T.M.1    Newport, J.W.2
  • 34
    • 0344668551 scopus 로고    scopus 로고
    • Securin and B-cyclin/CDK are the only essential targets of the APC
    • Thornton BR, Toczyski DP (2003) Securin and B-cyclin/CDK are the only essential targets of the APC. Nat Cell Biol 5:1090-1094
    • (2003) Nat Cell Biol , vol.5 , pp. 1090-1094
    • Thornton, B.R.1    Toczyski, D.P.2
  • 35
    • 18144434267 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling: Cell cycle arrest versus apoptosis
    • Pietenpol JA, Stewart ZA (2002) Cell cycle checkpoint signaling: cell cycle arrest versus apoptosis. Toxicology 181-182:475-481
    • (2002) Toxicology , vol.181-182 , pp. 475-481
    • Pietenpol, J.A.1    Stewart, Z.A.2
  • 36
    • 0033634990 scopus 로고    scopus 로고
    • Cell cycle regulatory failure in neurones: Causes and consequences
    • Nagy Z (2000) Cell cycle regulatory failure in neurones: causes and consequences. Neurobiol Aging 21:761-769
    • (2000) Neurobiol Aging , vol.21 , pp. 761-769
    • Nagy, Z.1
  • 37
    • 33750920705 scopus 로고    scopus 로고
    • Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
    • DeGregori J, Johnson DG (2006) Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr Mol Med 6:739-748
    • (2006) Curr Mol Med , vol.6 , pp. 739-748
    • Degregori, J.1    Johnson, D.G.2
  • 38
    • 5444227823 scopus 로고    scopus 로고
    • B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage
    • Liu DX, Biswas SC, Greene LA (2004) B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage. J Neurosci 24:8720-8725
    • (2004) J Neurosci , vol.24 , pp. 8720-8725
    • Liu, D.X.1    Biswas, S.C.2    Greene, L.A.3
  • 39
    • 85006277004 scopus 로고    scopus 로고
    • Direct coupling of the cell cycle and cell death machinery by E2F
    • Nahle Z, Polakoff J, Davuluri RV et al (2002) Direct coupling of the cell cycle and cell death machinery by E2F. Nat Cell Biol 4:859-864
    • (2002) Nat Cell Biol , vol.4 , pp. 859-864
    • Nahle, Z.1    Polakoff, J.2    Davuluri, R.V.3
  • 40
    • 0037444453 scopus 로고    scopus 로고
    • Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1
    • Nguyen MD, Boudreau M, Kriz J et al (2003) Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. J Neurosci 23:2131-2140
    • (2003) J Neurosci , vol.23 , pp. 2131-2140
    • Nguyen, M.D.1    Boudreau, M.2    Kriz, J.3
  • 41
    • 0029981438 scopus 로고    scopus 로고
    • The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons
    • Lee MH, Nikolic M, Baptista CA et al (1996) The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons. Proc Natl Acad Sci USA 93:3259-3263
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3259-3263
    • Lee, M.H.1    Nikolic, M.2    Baptista, C.A.3
  • 42
    • 33750461663 scopus 로고    scopus 로고
    • P27 small interfering RNA induces cell death through elevating cell cycle activity in cultured cortical neurons: A proof-of-concept study
    • Akashiba H, Matsuki N, Nishiyama N (2006) p27 small interfering RNA induces cell death through elevating cell cycle activity in cultured cortical neurons: a proof-of-concept study. Cell Mol Life Sci 63:2397-2404
    • (2006) Cell Mol Life Sci , vol.63 , pp. 2397-2404
    • Akashiba, H.1    Matsuki, N.2    Nishiyama, N.3
  • 43
    • 2442703950 scopus 로고    scopus 로고
    • Flavopiridol inhibits the growth of GL261 gliomas in vivo: Implications for malignant glioma therapy
    • Newcomb EW, Tamasdan C, Entzminger Y et al (2004) Flavopiridol inhibits the growth of GL261 gliomas in vivo: implications for malignant glioma therapy. Cell Cycle 3:230-234
    • (2004) Cell Cycle , vol.3 , pp. 230-234
    • Newcomb, E.W.1    Tamasdan, C.2    Entzminger, Y.3
  • 44
    • 0347917093 scopus 로고    scopus 로고
    • Cell-cycle targeted therapies
    • Swanton C (2004) Cell-cycle targeted therapies. Lancet Oncol 5:27-36
    • (2004) Lancet Oncol , vol.5 , pp. 27-36
    • Swanton, C.1
  • 45
    • 2342591929 scopus 로고    scopus 로고
    • Small molecule inhibitors targeting cyclin-dependent kinases as anticancer agents
    • Dai Y, Grant S (2004) Small molecule inhibitors targeting cyclin-dependent kinases as anticancer agents. Curr Oncol Rep 6:123-130
    • (2004) Curr Oncol Rep , vol.6 , pp. 123-130
    • Dai, Y.1    Grant, S.2
  • 46
    • 0037665145 scopus 로고    scopus 로고
    • Roscovitine and other purines as kinase inhibitors. from starfish oocytes to clinical trials
    • Meijer L, Raymond E (2003) Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials. Acc Chem Res 36:417-425
    • (2003) Acc Chem Res , vol.36 , pp. 417-425
    • Meijer, L.1    Raymond, E.2
  • 47
    • 0029092168 scopus 로고
    • Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases
    • Abraham RT, Acquarone M, Andersen A et al (1995) Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases. Biol Cell 83:105-120
    • (1995) Biol Cell , vol.83 , pp. 105-120
    • Abraham, R.T.1    Acquarone, M.2    Andersen, A.3
  • 48
    • 0030031514 scopus 로고    scopus 로고
    • Cyclin D1 is an essential mediator of apoptotic neuronal cell death
    • Kranenburg O, van der Eb AJ, Zantema A (1996) Cyclin D1 is an essential mediator of apoptotic neuronal cell death. Embo J 15:46-54
    • (1996) Embo J , vol.15 , pp. 46-54
    • Kranenburg, O.1    Van Der Eb, A.J.2    Zantema, A.3
  • 49
    • 0032905937 scopus 로고    scopus 로고
    • Transient hypoxia may lead to neuronal proliferation in the developing mammalian brain: From apoptosis to cell cycle completion
    • Bossenmeyer-Pourie C, Chihab R, Schroeder H et al (1999) Transient hypoxia may lead to neuronal proliferation in the developing mammalian brain: from apoptosis to cell cycle completion. Neuroscience 91:221-231
    • (1999) Neuroscience , vol.91 , pp. 221-231
    • Bossenmeyer-Pourie, C.1    Chihab, R.2    Schroeder, H.3
  • 50
    • 0034192510 scopus 로고    scopus 로고
    • Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage
    • Park DS, Morris EJ, Bremner R et al (2000) Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage. J Neurosci 20:3104-3114
    • (2000) J Neurosci , vol.20 , pp. 3104-3114
    • Park, D.S.1    Morris, E.J.2    Bremner, R.3
  • 51
    • 0043073209 scopus 로고    scopus 로고
    • Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis
    • Jorda EG, Verdaguer E, Canudas AM et al (2003) Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis. Neuropharmacology 45:672-683
    • (2003) Neuropharmacology , vol.45 , pp. 672-683
    • Jorda, E.G.1    Verdaguer, E.2    Canudas, A.M.3
  • 52
    • 25444460165 scopus 로고    scopus 로고
    • Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo
    • Rashidian J, Iyirhiaro G, Aleyasin H et al (2005) Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo. Proc Natl Acad Sci USA 102:14080-14085
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14080-14085
    • Rashidian, J.1    Iyirhiaro, G.2    Aleyasin, H.3
  • 53
    • 1542381057 scopus 로고    scopus 로고
    • Cell cycle regulation of neuronal apoptosis in development and disease
    • Becker EB, Bonni A (2004) Cell cycle regulation of neuronal apoptosis in development and disease. Prog Neurobiol 72:1-25
    • (2004) Prog Neurobiol , vol.72 , pp. 1-25
    • Becker, E.B.1    Bonni, A.2
  • 54
    • 1942520401 scopus 로고    scopus 로고
    • Astrocyte apoptosis: Implications for neuroprotection
    • Takuma K, Baba A, Matsuda T (2004) Astrocyte apoptosis: implications for neuroprotection. Prog Neurobiol 72:111-127
    • (2004) Prog Neurobiol , vol.72 , pp. 111-127
    • Takuma, K.1    Baba, A.2    Matsuda, T.3
  • 55
    • 33847749886 scopus 로고    scopus 로고
    • Inhibiting cell cycle progression reduces reactive astrogliosis initiated by scratch injury in vitro and by cerebral ischemia in vivo
    • Zhu Z, Zhang Q, Yu Z et al (2007) Inhibiting cell cycle progression reduces reactive astrogliosis initiated by scratch injury in vitro and by cerebral ischemia in vivo. Glia 55:546-558
    • (2007) Glia , vol.55 , pp. 546-558
    • Zhu, Z.1    Zhang, Q.2    Yu, Z.3
  • 56
    • 0344118173 scopus 로고    scopus 로고
    • Microglial cell cycle-associated proteins control microglial proliferation in vivo and in vitro and are regulated by GM-CSF and density-dependent inhibition
    • Koguchi K, Nakatsuji Y, Okuno T et al (2003) Microglial cell cycle-associated proteins control microglial proliferation in vivo and in vitro and are regulated by GM-CSF and density-dependent inhibition. J Neurosci Res 74:898-905
    • (2003) J Neurosci Res , vol.74 , pp. 898-905
    • Koguchi, K.1    Nakatsuji, Y.2    Okuno, T.3
  • 57
    • 33748607463 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of kainate-induced inward currents in microglia
    • Yamada J, Sawada M, Nakanishi H (2006) Cell cycle-dependent regulation of kainate-induced inward currents in microglia. Biochem Biophys Res Commun 349:913-919
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 913-919
    • Yamada, J.1    Sawada, M.2    Nakanishi, H.3
  • 58
    • 0035498803 scopus 로고    scopus 로고
    • Density dependent modulation of cell cycle protein expression in astrocytes
    • Nakatsuji Y, Miller RH (2001) Density dependent modulation of cell cycle protein expression in astrocytes. J Neurosci Res 66:487-496
    • (2001) J Neurosci Res , vol.66 , pp. 487-496
    • Nakatsuji, Y.1    Miller, R.H.2
  • 59
    • 0036231413 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity
    • Mirjany M, Ho L, Pasinetti GM (2002) Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity. J Pharmacol Exp Ther 301:494-500
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 494-500
    • Mirjany, M.1    Ho, L.2    Pasinetti, G.M.3
  • 60
    • 0035882278 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo
    • Ino H, Chiba T (2001) Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo. J Neurosci 21:6086-6094
    • (2001) J Neurosci , vol.21 , pp. 6086-6094
    • Ino, H.1    Chiba, T.2
  • 61
    • 0035805106 scopus 로고    scopus 로고
    • Characterization of cyclin D1 expression in a rat global model of cerebral ischemia
    • Small DL, Monette R, Fournier MC et al (2001) Characterization of cyclin D1 expression in a rat global model of cerebral ischemia. Brain Res 900:26-37
    • (2001) Brain Res , vol.900 , pp. 26-37
    • Small, D.L.1    Monette, R.2    Fournier, M.C.3
  • 62
    • 0031960759 scopus 로고    scopus 로고
    • Cell cycle-related gene expression in the adult rat brain: Selective induction of cyclin G1 and p21WAF1/CIP1 in neurons following focal cerebral ischemia
    • van Lookeren Campagne M, Gill R (1998) Cell cycle-related gene expression in the adult rat brain: selective induction of cyclin G1 and p21WAF1/CIP1 in neurons following focal cerebral ischemia. Neuroscience 84:1097-1112
    • (1998) Neuroscience , vol.84 , pp. 1097-1112
    • Van Lookeren Campagne, M.1    Gill, R.2
  • 63
    • 23444442242 scopus 로고    scopus 로고
    • Neuroprotective effects of novel small peptides in vitro and after brain injury
    • Faden AI, Movsesyan VA, Knoblach SM et al (2005) Neuroprotective effects of novel small peptides in vitro and after brain injury. Neuropharmacology 49:410-424
    • (2005) Neuropharmacology , vol.49 , pp. 410-424
    • Faden, A.I.1    Movsesyan, V.A.2    Knoblach, S.M.3
  • 64
    • 33646723866 scopus 로고    scopus 로고
    • Proteomic analysis of injured spinal cord tissue proteins using 2-DE and MALDI-TOF MS
    • Kang SK, So HH, Moon YS et al (2006) Proteomic analysis of injured spinal cord tissue proteins using 2-DE and MALDI-TOF MS. Proteomics 6:2797-2812
    • (2006) Proteomics , vol.6 , pp. 2797-2812
    • Kang, S.K.1    So, H.H.2    Moon, Y.S.3
  • 65
    • 4744366168 scopus 로고    scopus 로고
    • Patterns of gene expression reveal a temporally orchestrated wound healing response in the injured spinal cord
    • Velardo MJ, Burger C, Williams PR et al (2004) Patterns of gene expression reveal a temporally orchestrated wound healing response in the injured spinal cord. J Neurosci 24:8562-8576
    • (2004) J Neurosci , vol.24 , pp. 8562-8576
    • Velardo, M.J.1    Burger, C.2    Williams, P.R.3
  • 66
    • 0037103863 scopus 로고    scopus 로고
    • Altered expression of novel genes in the cerebral cortex following experimental brain injury
    • Kobori N, Clifton GL, Dash P (2002) Altered expression of novel genes in the cerebral cortex following experimental brain injury. Brain Res Mol Brain Res 104:148-158
    • (2002) Brain Res Mol Brain Res , vol.104 , pp. 148-158
    • Kobori, N.1    Clifton, G.L.2    Dash, P.3
  • 67
    • 0034647609 scopus 로고    scopus 로고
    • P53-independent transient p21(WAF1/CIP1) mRNA induction in the rat brain following experimental traumatic injury
    • Katano H, Masago A, Taki H et al (2000) p53-independent transient p21(WAF1/CIP1) mRNA induction in the rat brain following experimental traumatic injury. Neuroreport 11:2073-2078
    • (2000) Neuroreport , vol.11 , pp. 2073-2078
    • Katano, H.1    Masago, A.2    Taki, H.3
  • 68
    • 3042552705 scopus 로고    scopus 로고
    • Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats
    • Tanaka H, Yamashita T, Yachi K et al (2004) Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats. Neuroscience 127:155-164
    • (2004) Neuroscience , vol.127 , pp. 155-164
    • Tanaka, H.1    Yamashita, T.2    Yachi, K.3
  • 69
    • 0028255722 scopus 로고
    • Heterogeneity among astrocytes in reactive gliosis
    • Hoke A, Silver J (1994) Heterogeneity among astrocytes in reactive gliosis. Perspect Dev Neurobiol 2:269-274
    • (1994) Perspect Dev Neurobiol , vol.2 , pp. 269-274
    • Hoke, A.1    Silver, J.2
  • 70
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes: Cellular and molecular cues to biological function
    • Ridet JL, Malhotra SK, Privat A et al (1997) Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 20:570-577
    • (1997) Trends Neurosci , vol.20 , pp. 570-577
    • Ridet, J.L.1    Malhotra, S.K.2    Privat, A.3
  • 71
    • 0030560753 scopus 로고    scopus 로고
    • Regeneration of cut adult axons fails even in the presence of continuous aligned glial pathways
    • Davies SJ, Field PM, Raisman G (1996) Regeneration of cut adult axons fails even in the presence of continuous aligned glial pathways. Exp Neurol 142:203-216
    • (1996) Exp Neurol , vol.142 , pp. 203-216
    • Davies, S.J.1    Field, P.M.2    Raisman, G.3
  • 72
    • 1542317072 scopus 로고    scopus 로고
    • Reactive astrocytes protect tissue and preserve function after spinal cord injury
    • Faulkner JR, Herrmann JE, Woo MJ et al (2004) Reactive astrocytes protect tissue and preserve function after spinal cord injury. J Neurosci 24:2143-2155
    • (2004) J Neurosci , vol.24 , pp. 2143-2155
    • Faulkner, J.R.1    Herrmann, J.E.2    Woo, M.J.3
  • 74
    • 33749462602 scopus 로고    scopus 로고
    • Suppression of astroglial scar formation and enhanced axonal regeneration associated with functional recovery in a spinal cord injury rat model by the cell cycle inhibitor olomoucine
    • Tian DS, Yu ZY, Xie MJ et al (2006) Suppression of astroglial scar formation and enhanced axonal regeneration associated with functional recovery in a spinal cord injury rat model by the cell cycle inhibitor olomoucine. J Neurosci Res 84:1053-1063
    • (2006) J Neurosci Res , vol.84 , pp. 1053-1063
    • Tian, D.S.1    Yu, Z.Y.2    Xie, M.J.3
  • 75
    • 4544308191 scopus 로고    scopus 로고
    • A neuroprotective role of glial cell line-derived neurotrophic factor following moderate spinal cord contusion injury
    • Iannotti C, Ping Zhang Y, Shields CB et al (2004) A neuroprotective role of glial cell line-derived neurotrophic factor following moderate spinal cord contusion injury. Exp Neurol 189:317-332
    • (2004) Exp Neurol , vol.189 , pp. 317-332
    • Iannotti, C.1    Ping Zhang, Y.2    Shields, C.B.3
  • 76
    • 34247476375 scopus 로고    scopus 로고
    • Nestin-CreER mice reveal DNA synthesis by nonapoptotic neurons following cerebral ischemia-hypoxia
    • Burns KA, Ayoub AE, Breunig JJ et al (2007) Nestin-CreER mice reveal DNA synthesis by nonapoptotic neurons following cerebral ischemia-hypoxia. Cereb Cortex
    • (2007) Cereb Cortex
    • Burns, K.A.1    Ayoub, A.E.2    Breunig, J.J.3
  • 77
    • 9344264624 scopus 로고    scopus 로고
    • Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain
    • Kuan CY, Schloemer AJ, Lu A et al (2004) Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain. J Neurosci 24:10763-10772
    • (2004) J Neurosci , vol.24 , pp. 10763-10772
    • Kuan, C.Y.1    Schloemer, A.J.2    Lu, A.3
  • 78
    • 0033962198 scopus 로고    scopus 로고
    • Cyclin D1 and Cdk4 protein induction in motor neurons after transient spinal cord ischemia in rabbits
    • Sakurai M, Hayashi T, Abe K et al (2000) Cyclin D1 and Cdk4 protein induction in motor neurons after transient spinal cord ischemia in rabbits. Stroke 31:200-207
    • (2000) Stroke , vol.31 , pp. 200-207
    • Sakurai, M.1    Hayashi, T.2    Abe, K.3
  • 79
    • 27144478006 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation
    • Cicero S, Herrup K (2005) Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci 25:9658-9668
    • (2005) J Neurosci , vol.25 , pp. 9658-9668
    • Cicero, S.1    Herrup, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.