Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain

Journal of Neuroscience

Volumn 24, Issue 47, 2004, Pages 10763-10772

  Kuan, Chia Yi ^a,e   Schloemer, Aryn J ^a   Lu, Aigang ^b,f   Burns, Kevin A ^a   Weng, Wei Lan ^a   Williams, Michael T ^a   Strauss, Kenneth I ^b   Vorhees, Charles V ^a   Flavell, Richard A ^c   Davis, Roger I ^d   Sharp, Frank R ^b,f   Rakic, Pasko ^c  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^e CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; BrdU; Cell cycle; Hypoxia; Ischemia; Neurogenesis

Indexed keywords

BROXURIDINE; CELL MARKER; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; KAINIC ACID; KI 67 ANTIGEN; PROTEIN P16; PROTEIN P16INK4; PROTEIN P27; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA SYNTHESIS; HYPOXIA; IMMUNOCOMPETENT CELL; ISCHEMIA; MOUSE; NERVE CELL NECROSIS; NERVOUS SYSTEM DEVELOPMENT; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ADRENALECTOMY; AGE FACTORS; ANIMALS; APOPTOSIS; BRAIN; BRAIN INJURIES; BROMODEOXYURIDINE; DNA; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; HYPOXIA-ISCHEMIA, BRAIN; IN SITU NICK-END LABELING; KAINIC ACID; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; S PHASE;

EID: 9344264624     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3883-04.2004     Document Type: Article

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