메뉴 건너뛰기




Volumn 13, Issue 5, 2013, Pages 542-557

Anti-inflammatory phytochemicals for chemoprevention of colon cancer

Author keywords

Chemoprevention; Colon cancer; Inflammation; Natural compounds; Phytochemicals

Indexed keywords

ANTIINFLAMMATORY AGENT; ARACHIDONATE 5 LIPOXYGENASE; ASTAXANTHIN; BOSWELLIC ACID; CINEOLE; CURCUMIN; CYCLOOXYGENASE 2; CYTOKINE; DIOSGENIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LICOFELONE; LINAZOLAST; LUPEOL; N [3 (AMINOMETHYL) BENZYL] ACETAMIDINE; NONSTEROID ANTIINFLAMMATORY AGENT; OLEANOLIC ACID; PIPERINE; PIRINIXIC ACID; PLANT MEDICINAL PRODUCT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; YS 121;

EID: 84886675158     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/15680096113139990036     Document Type: Review
Times cited : (66)

References (247)
  • 1
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society, Atlanta, Ga: American Cancer Society
    • American Cancer Society. Cancer Facts & Figures 2013, Atlanta, Ga: American Cancer Society.
    • (2013) Cancer Facts & Figures
  • 2
    • 77951433203 scopus 로고    scopus 로고
    • Effectiveness of whole grain consumption in the prevention of colorectal cancer: Meta-analysis of cohort studies
    • Haas, P.; Machado, M. J.; Anton, A. A.; Silva, A. S.; De Francisco, A. Effectiveness of whole grain consumption in the prevention of colorectal cancer: Meta-analysis of cohort studies. Int. J. Food Sci. Nutr. 2009, 21, 1-13.
    • (2009) Int. J. Food Sci. Nutr , vol.21 , pp. 1-13
    • Haas, P.1    Machado, M.J.2    Anton, A.A.3    Silva, A.S.4    de Francisco, A.5
  • 3
    • 79957620044 scopus 로고    scopus 로고
    • Foods and food groups associated with the incidence of colorectal polyps: The Adventist Health Study
    • Tantamango, Y. M.; Knutsen, S. F.; Beeson, W. L.; Fraser, G.; Sabate, J. Foods and food groups associated with the incidence of colorectal polyps: the Adventist Health Study. Nutr. Cancer. 2011, 63 (4), 565-572.
    • (2011) Nutr. Cancer , vol.63 , Issue.4 , pp. 565-572
    • Tantamango, Y.M.1    Knutsen, S.F.2    Beeson, W.L.3    Fraser, G.4    Sabate, J.5
  • 4
    • 31144461664 scopus 로고    scopus 로고
    • Helicobacter infection and gastric neoplasia
    • Peek, Jr. R. M.; Crabtree, J. E. Helicobacter infection and gastric neoplasia. J. Pathol. 2006, 208 (2), 233-248.
    • (2006) J. Pathol , vol.208 , Issue.2 , pp. 233-248
    • Peek, R.M.1    Crabtree, J.E.2
  • 5
    • 6344263598 scopus 로고    scopus 로고
    • Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: Implications for lung inflammation and cancer
    • Martey, C. A.; Pollock, S. J.; Turner, C. K.; O'Reilly, K. M.; Baglole, C. J.; Phipps, R. P.; Sime, P. J. Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer. Am. J. Physiol. Lung Cell Mol. Physiol. 2004, 287 (5), L981-L991.
    • (2004) Am. J. Physiol. Lung Cell Mol. Physiol , vol.287 , Issue.5
    • Martey, C.A.1    Pollock, S.J.2    Turner, C.K.3    O'Reilly, K.M.4    Baglole, C.J.5    Phipps, R.P.6    Sime, P.J.7
  • 6
    • 26044444704 scopus 로고    scopus 로고
    • Role of inflammation in pancreatic carcinogenesis and the implications for future therapy
    • Garcea, G.; Dennison, A. R.; Steward, W. P.; Berry, D. P. Role of inflammation in pancreatic carcinogenesis and the implications for future therapy. Pancreatology 2005, 5 (6), 514-529.
    • (2005) Pancreatology , vol.5 , Issue.6 , pp. 514-529
    • Garcea, G.1    Dennison, A.R.2    Steward, W.P.3    Berry, D.P.4
  • 7
    • 0030931156 scopus 로고    scopus 로고
    • C and hepatocellular carcinoma
    • Di Bisceglie, A. M. Hepatitis C and hepatocellular carcinoma. Hepatology 1997, 26 (3), 34S-38S.
    • (1997) Hepatology , vol.26 , Issue.3
    • Di, B.1    Hepatitis, A.M.2
  • 9
    • 0037011668 scopus 로고    scopus 로고
    • Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis
    • Offersen, B. V.; Knap, M. M.; Marcussen, N.; Horsman, M. R.; Hamilton-Dutoit, S.; Overgaard, J. Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis. Br. J. Cancer 2002, 87 (12), 1422-1430.
    • (2002) Br. J. Cancer , vol.87 , Issue.12 , pp. 1422-1430
    • Offersen, B.V.1    Knap, M.M.2    Marcussen, N.3    Horsman, M.R.4    Hamilton-Dutoit, S.5    Overgaard, J.6
  • 11
    • 0033831517 scopus 로고    scopus 로고
    • Infections as a major preventable cause of human cancer
    • Kuper, H.; Adami, H. O.; Trichopoulos, D. Infections as a major preventable cause of human cancer, J. Intern. Med. 2000, 248, 171-183.
    • (2000) J. Intern. Med , vol.248 , pp. 171-183
    • Kuper, H.1    Adami, H.O.2    Trichopoulos, D.3
  • 12
    • 80053137426 scopus 로고    scopus 로고
    • Deletion of cyclooxygenase 2 in mouse mammary epithelial cells delays breast cancer onset through augmentation of type 1 immune responses in tumors
    • Markosyan, N.; Chen, E. P.; Ndong, V. N.; Yao, Y.; Sterner, C. J.; Chodosh, L. A.; Lawson, J. A.; Fitzgerald, G. A.; Smyth, E. M. Deletion of cyclooxygenase 2 in mouse mammary epithelial cells delays breast cancer onset through augmentation of type 1 immune responses in tumors. Carcinogenesis 2011, 32 (10), 1441-1449.
    • (2011) Carcinogenesis , vol.32 , Issue.10 , pp. 1441-1449
    • Markosyan, N.1    Chen, E.P.2    Ndong, V.N.3    Yao, Y.4    Sterner, C.J.5    Chodosh, L.A.6    Lawson, J.A.7    Fitzgerald, G.A.8    Smyth, E.M.9
  • 13
    • 41149095173 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 plays a critical role in UV-induced skin carcinogenesis
    • Rundhaug, J. E.; Fischer, S. M. Cyclo-oxygenase-2 plays a critical role in UV-induced skin carcinogenesis. Photochem. Photobiol. 2008, 84 (2), 322-329.
    • (2008) Photochem. Photobiol , vol.84 , Issue.2 , pp. 322-329
    • Rundhaug, J.E.1    Fischer, S.M.2
  • 16
    • 34248396797 scopus 로고    scopus 로고
    • Colorectal carcinoma development in inducible nitric oxide synthase-deficient mice with dextran sulfate sodium-induced ulcerative colitis
    • Seril, D. N.; Liao, J.; Yang, G. Y. Colorectal carcinoma development in inducible nitric oxide synthase-deficient mice with dextran sulfate sodium-induced ulcerative colitis. Mol. Carcinog. 2007, 46 (5), 341-353.
    • (2007) Mol. Carcinog , vol.46 , Issue.5 , pp. 341-353
    • Seril, D.N.1    Liao, J.2    Yang, G.Y.3
  • 17
    • 57649219307 scopus 로고    scopus 로고
    • TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB
    • Edelblum, K. L.; Goettel, J. A.; Koyama, T.; McElroy, S. J.; Yan, F.; Polk, D. B. TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB. J. Biol. Chem. 2008, 283 (43), 29485-29494.
    • (2008) J. Biol. Chem , vol.283 , Issue.43 , pp. 29485-29494
    • Edelblum, K.L.1    Goettel, J.A.2    Koyama, T.3    McElroy, S.J.4    Yan, F.5    Polk, D.B.6
  • 22
    • 79952249828 scopus 로고    scopus 로고
    • Nitrative and oxidative DNA damage as potential survival biomarkers for nasopharyngeal carcinoma
    • Huang, Y. J; Zhang, B.B; Ma, N; Murata, M; Tang, A. Z; Huang, G. W. Nitrative and oxidative DNA damage as potential survival biomarkers for nasopharyngeal carcinoma. Med. Oncol. 2011 28 (1), 377-384.
    • (2011) Med. Oncol , vol.28 , Issue.1 , pp. 377-384
    • Huang, Y.J.1    Zhang, B.B.2    Ma, N.3    Murata, M.4    Tang, A.Z.5    Huang, G.W.6
  • 23
    • 0035170217 scopus 로고    scopus 로고
    • Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes
    • Jaiswal, M.; LaRusso, N. F.; Shapiro, R. A.; Billiar, T. R.; Gores, G. J. Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes. Gastroenterology 2001, 120 (1), 190-199.
    • (2001) Gastroenterology , vol.120 , Issue.1 , pp. 190-199
    • Jaiswal, M.1    Larusso, N.F.2    Shapiro, R.A.3    Billiar, T.R.4    Gores, G.J.5
  • 24
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens, L. M.; Werb, Z. Inflammation and cancer. Nature 2002, 420 (6917), 860-867.
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 27
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill, F.; Mantovani, A. Inflammation and cancer: back to Virchow? Lancet 2001, 357 (9255), 539-545.
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 29
    • 37149034658 scopus 로고    scopus 로고
    • Hyperexpression of cyclooxygenase 2 in the lupus immune system and effect of cyclooxygenase 2 inhibitor diet therapy in a murine model of systemic lupus erythematosus
    • Zhang, L.; Bertucci, A. M.; Smith, K. A.; Xu, L.; Datta, S. K. Hyperexpression of cyclooxygenase 2 in the lupus immune system and effect of cyclooxygenase 2 inhibitor diet therapy in a murine model of systemic lupus erythematosus. Arthritis Rheum. 2007, 56, 4132-4141.
    • (2007) Arthritis Rheum , vol.56 , pp. 4132-4141
    • Zhang, L.1    Bertucci, A.M.2    Smith, K.A.3    Xu, L.4    Datta, S.K.5
  • 31
    • 0037126069 scopus 로고    scopus 로고
    • Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis
    • Muller-Decker, K.; Neufang, G.; Berger, I.; Neumann, M.; Marks, F.; Furstenberger, G. Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis. PNAS. 2002, 99 (19), 12483-12488.
    • (2002) PNAS , vol.99 , Issue.19 , pp. 12483-12488
    • Muller-Decker, K.1    Neufang, G.2    Berger, I.3    Neumann, M.4    Marks, F.5    Furstenberger, G.6
  • 32
    • 2342587509 scopus 로고    scopus 로고
    • Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice
    • Oshima, H.; Oshima, M.; Inaba, K.; Taketo, M. M. Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice. EMBO J. 2004, 23 (7), 1669-1678.
    • (2004) EMBO J , vol.23 , Issue.7 , pp. 1669-1678
    • Oshima, H.1    Oshima, M.2    Inaba, K.3    Taketo, M.M.4
  • 35
    • 84876728485 scopus 로고    scopus 로고
    • Prognostic value of COX-2 expression in patients with non-small cell lung cancer: A systematic review and meta-analysis
    • Zhan, P; Qian, Q; Yu, L. K. Prognostic value of COX-2 expression in patients with non-small cell lung cancer: a systematic review and meta-analysis. J. Thorac. Dis. 2013 5 (1), 40-47.
    • (2013) J. Thorac. Dis , vol.5 , Issue.1 , pp. 40-47
    • Zhan, P.1    Qian, Q.2    Yu, L.K.3
  • 36
    • 84875171594 scopus 로고    scopus 로고
    • Prognostic Significance of COX-2 Immunohistochemical Expression in Colorectal Cancer: A Meta-Analysis of the Literature
    • Peng, L; Zhou, Y; Wang, Y; Mou, H; Zhao, Q. Prognostic Significance of COX-2 Immunohistochemical Expression in Colorectal Cancer: A Meta-Analysis of the Literature. PLoS One. 2013, 8 (3), e58891.
    • (2013) PLoS One , vol.8 , Issue.3
    • Peng, L.1    Zhou, Y.2    Wang, Y.3    Mou, H.4    Zhao, Q.5
  • 37
    • 0037086261 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ
    • Half, E.; Tang, X. M.; Gwyn, K.; Sahin, A.; Wathen, K.; Sinicrope, F. A. Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ. Cancer Res. 2002, 62 (6), 1676-1681.
    • (2002) Cancer Res , vol.62 , Issue.6 , pp. 1676-1681
    • Half, E.1    Tang, X.M.2    Gwyn, K.3    Sahin, A.4    Wathen, K.5    Sinicrope, F.A.6
  • 39
    • 0037081197 scopus 로고    scopus 로고
    • Cyclooxygenase-1 is up-regulated in cervical carcinomas: Autocrine/paracrine regulation of cyclooxygenase-2, prostaglandin e receptors, and angiogenic factors by cyclooxygenase-1
    • Sales, K. J.; Katz, A. A.; Howard, B.; Soeters, R. P.; Millar, R. P.; Jabbour, H. N. Cyclooxygenase-1 is up-regulated in cervical carcinomas: autocrine/paracrine regulation of cyclooxygenase-2, prostaglandin e receptors, and angiogenic factors by cyclooxygenase-1. Cancer Res. 2002, 62 (2), 424-432.
    • (2002) Cancer Res , vol.62 , Issue.2 , pp. 424-432
    • Sales, K.J.1    Katz, A.A.2    Howard, B.3    Soeters, R.P.4    Millar, R.P.5    Jabbour, H.N.6
  • 40
    • 0035476888 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 and inducible nitric oxide synthase in human ovarian tumors and tumor-associated macrophages
    • Klimp, A. H.; Hollema, H.; Kempinga, C.; van der Zee, A. G.; de Vries, E. G.; Daemen, T. Expression of cyclooxygenase-2 and inducible nitric oxide synthase in human ovarian tumors and tumor-associated macrophages. Cancer Res. 2001, 61 (19), 7305-7309.
    • (2001) Cancer Res , vol.61 , Issue.19 , pp. 7305-7309
    • Klimp, A.H.1    Hollema, H.2    Kempinga, C.3    van der Zee, A.G.4    de Vries, E.G.5    Daemen, T.6
  • 41
    • 0035866783 scopus 로고    scopus 로고
    • Differential expression of cyclooxygenase-2 and its regulation by tumor necrosis factor-alpha in normal and malignant prostate cells
    • Subbarayan, V.; Sabichi, A. L.; Llansa, N.; Lippman, S. M.; Menter, D. G. Differential expression of cyclooxygenase-2 and its regulation by tumor necrosis factor-alpha in normal and malignant prostate cells. Cancer Res. 2001, 61 (6), 2720-2726.
    • (2001) Cancer Res , vol.61 , Issue.6 , pp. 2720-2726
    • Subbarayan, V.1    Sabichi, A.L.2    Llansa, N.3    Lippman, S.M.4    Menter, D.G.5
  • 45
    • 18444408375 scopus 로고    scopus 로고
    • COX-2: A molecular target for colorectal cancer prevention
    • Brown, J. R.; DuBois, R. N. COX-2: a molecular target for colorectal cancer prevention. J. Clin. Oncol. 2005, 23, 2840-2855.
    • (2005) J. Clin. Oncol , vol.23 , pp. 2840-2855
    • Brown, J.R.1    Dubois, R.N.2
  • 48
    • 0027993458 scopus 로고
    • Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
    • Eberhart, C. E.; Coffey, R. J.; Radhika, A.; Giardiello, F. M.; Ferrenbach, S.; DuBois, R. N. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterol. 1994, 107, 1183-1188.
    • (1994) Gastroenterol , vol.107 , pp. 1183-1188
    • Eberhart, C.E.1    Coffey, R.J.2    Radhika, A.3    Giardiello, F.M.4    Ferrenbach, S.5    Dubois, R.N.6
  • 49
    • 0029913633 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors
    • DuBois, R. N.; Radhika, A.; Reddy, B. S.; Entingh, A. J. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterol. 1996, 110, 1259-1262.
    • (1996) Gastroenterol , vol.110 , pp. 1259-1262
    • Dubois, R.N.1    Radhika, A.2    Reddy, B.S.3    Entingh, A.J.4
  • 50
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii, M.; DuBois, R. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995, 83, 493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    Dubois, R.2
  • 51
    • 0026761738 scopus 로고
    • Aspirin and the potential role of prostaglandins in colon cancer
    • Marnett, L.J. Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res. 1992, 52, 5575-5589.
    • (1992) Cancer Res , vol.52 , pp. 5575-5589
    • Marnett, L.J.1
  • 52
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith, W. L.; DeWitt, D. L; Garavito, R. M. Cyclooxygenases: structural, cellular, and molecular biology. Ann. Rev. Biochem. 2000, 69, 145-182.
    • (2000) Ann. Rev. Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    Dewitt, D.L.2    Garavito, R.M.3
  • 54
    • 0030879456 scopus 로고    scopus 로고
    • Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: Independence from COX-2 protein expression
    • Elder, D. J.; Halton, D. E.; Hague, A.; Paraskeva, C. Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression. Clin. Cancer Res. 1997, 3, 1679-1683.
    • (1997) Clin. Cancer Res , vol.3 , pp. 1679-1683
    • Elder, D.J.1    Halton, D.E.2    Hague, A.3    Paraskeva, C.4
  • 56
    • 0036735391 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells
    • Tang, X.; Sun, Y. J.; Half, E.; Kuo, M. T.; Sinicrope, F. Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells. Cancer Res. 2002, 62 (17), 4903-4908.
    • (2002) Cancer Res , vol.62 , Issue.17 , pp. 4903-4908
    • Tang, X.1    Sun, Y.J.2    Half, E.3    Kuo, M.T.4    Sinicrope, F.5
  • 57
    • 0036829336 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells
    • Sun, Y.; Tang, X. M.; Half, E.; Kuo, M. T.; Sinicrope, F. A. Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells. Cancer Res. 2002, 62 (21), 6323-6328.
    • (2002) Cancer Res , vol.62 , Issue.21 , pp. 6323-6328
    • Sun, Y.1    Tang, X.M.2    Half, E.3    Kuo, M.T.4    Sinicrope, F.A.5
  • 58
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • Tsujii, M.; Kawano, S.; Tsuji, S.; Sawaoka, H.; Hori, M.; DuBois, R. N. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998, 93 (5), 705-716.
    • (1998) Cell , vol.93 , Issue.5 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    Dubois, R.N.6
  • 59
    • 0034667497 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells
    • Souza, R. F.; Shewmake, K.; Beer, D. G.; Cryer, B.; Spechler, S. J. Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. Cancer Res. 2000, 60 (20), 5767-5772.
    • (2000) Cancer Res , vol.60 , Issue.20 , pp. 5767-5772
    • Souza, R.F.1    Shewmake, K.2    Beer, D.G.3    Cryer, B.4    Spechler, S.J.5
  • 60
    • 33750102847 scopus 로고    scopus 로고
    • Therapeutic options for 5-lipoxygenase inhibitors
    • Werz, O.; Steinhilber, D. Therapeutic options for 5-lipoxygenase inhibitors. Pharmacol. Ther. 2006, 112, 701-718.
    • (2006) Pharmacol. Ther , vol.112 , pp. 701-718
    • Werz, O.1    Steinhilber, D.2
  • 61
    • 33749612562 scopus 로고    scopus 로고
    • What are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis?
    • Furstenberger, G.; Krieg, P.; Muller-Decker, K.; Habenicht, A. J. What are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis? Int J Cancer 2006, 119, 2247-2254.
    • (2006) Int J Cancer , vol.119 , pp. 2247-2254
    • Furstenberger, G.1    Krieg, P.2    Muller-Decker, K.3    Habenicht, A.J.4
  • 62
    • 0035164723 scopus 로고    scopus 로고
    • Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis
    • Kelavkar, U. P.; Nixon, J. B.; Cohen, C.; Dillehay, D.; Eling, T. E.; Badr, K. F. Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. Carcinogenesis 2001, 22(11), 1765-1773.
    • (2001) Carcinogenesis , vol.22 , Issue.11 , pp. 1765-1773
    • Kelavkar, U.P.1    Nixon, J.B.2    Cohen, C.3    Dillehay, D.4    Eling, T.E.5    Badr, K.F.6
  • 63
    • 0026702580 scopus 로고
    • Differential expression of arachidonate 5-lipoxygenase transcripts in human brain tumors: Evidence for the expression of a multitranscript family
    • Boado, R. J.; Pardridge, W. M.; Vinters, H. V.; Black, K. L. Differential expression of arachidonate 5-lipoxygenase transcripts in human brain tumors: evidence for the expression of a multitranscript family. PNAS. 1992, 89(19), 9044-9048.
    • (1992) PNAS , vol.89 , Issue.19 , pp. 9044-9048
    • Boado, R.J.1    Pardridge, W.M.2    Vinters, H.V.3    Black, K.L.4
  • 64
    • 0036971423 scopus 로고    scopus 로고
    • 5-Lipoxygenase and leukotrieneB(4) receptor are expressed in humanpancreatic cancersbut not in pancreatic ducts in normal tissue
    • Hennig, R.; Ding, X. Z.; Tong, W.; Schneider, M. B.; Standop, J.; Friess, H.; Büchler, M. W.; Pour, P. M.; Adrian, T. E. 5-Lipoxygenase and leukotrieneB(4) receptor are expressed in humanpancreatic cancersbut not in pancreatic ducts in normal tissue. Am J Pathol. 2002, 161, 421-428.
    • (2002) Am J Pathol , vol.161 , pp. 421-428
    • Hennig, R.1    Ding, X.Z.2    Tong, W.3    Schneider, M.B.4    Standop, J.5    Friess, H.6    Büchler, M.W.7    Pour, P.M.8    Adrian, T.E.9
  • 65
    • 9244221653 scopus 로고    scopus 로고
    • Targetingmultiple signaling pathways as a strategy for managing prostate cancer: Multifocal signal modulation therapy
    • McCarty, M. F. Targetingmultiple signaling pathways as a strategy for managing prostate cancer: multifocal signal modulation therapy. Integr. Cancer Ther. 2004, 3, 349-380.
    • (2004) Integr. Cancer Ther , vol.3 , pp. 349-380
    • McCarty, M.F.1
  • 66
    • 1242295294 scopus 로고    scopus 로고
    • Rapid induction of apoptosis in prostate cancer cells by selenium: Reversal by metabolites of arachidonate 5-lipoxygenase
    • Ghosh, J. Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase. Biochem. Biophys. Res. Commun. 2004, 315, 624-635.
    • (2004) Biochem. Biophys. Res. Commun , vol.315 , pp. 624-635
    • Ghosh, J.1
  • 69
    • 17844390400 scopus 로고    scopus 로고
    • Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke
    • Ye, Y. N.; Wu, W. K.; Shin, V. Y.; Bruce, I. C.; Wong, B. C.; Cho, C. H. Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke. Carcinogenesis 2005, 26 (4), 827-834.
    • (2005) Carcinogenesis , vol.26 , Issue.4 , pp. 827-834
    • Ye, Y.N.1    Wu, W.K.2    Shin, V.Y.3    Bruce, I.C.4    Wong, B.C.5    Cho, C.H.6
  • 70
    • 83055195235 scopus 로고    scopus 로고
    • Chemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: Potential implications for human colon cancer prevention
    • Mohammed, A.; Janakiram, N. B.; Li, Q.; Choi, C. I.; Zhang, Y.; Steele, V. E.; Rao, C. V. Chemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: potential implications for human colon cancer prevention. Cancer Prev. Res. 2011, 4 (12), 2015-2026.
    • (2011) Cancer Prev. Res , vol.4 , Issue.12 , pp. 2015-2026
    • Mohammed, A.1    Janakiram, N.B.2    Li, Q.3    Choi, C.I.4    Zhang, Y.5    Steele, V.E.6    Rao, C.V.7
  • 71
    • 80051489648 scopus 로고    scopus 로고
    • Chemopreventive efficacy and mechanism of licofelone in a mouse lung tumor model via aspiration
    • Sharma, S.; Lee, J.; Zhou, J.; Steele, V. E. Chemopreventive efficacy and mechanism of licofelone in a mouse lung tumor model via aspiration. Cancer Prev Res (Phila). 2011, 4 (8), 1233-1242.
    • (2011) Cancer Prev Res (Phila) , vol.4 , Issue.8 , pp. 1233-1242
    • Sharma, S.1    Lee, J.2    Zhou, J.3    Steele, V.E.4
  • 72
    • 0031705797 scopus 로고    scopus 로고
    • Inhibitors of lipoxygenase: A new class of cancer chemopreventive agents
    • Rioux, N.; Castonguay, A. Inhibitors of lipoxygenase: a new class of cancer chemopreventive agents. Carcinogenesis 1998, 19 (8), 1393-1400.
    • (1998) Carcinogenesis , vol.19 , Issue.8 , pp. 1393-1400
    • Rioux, N.1    Castonguay, A.2
  • 73
    • 0028234629 scopus 로고
    • Inhibition of two-stage skin carcinogenesis as well as complete skin carcinogenesis by oral administration of TMK688, a potent lipoxygenase inhibitor
    • Jiang, H.; Yamamoto, S.; Kato, R. Inhibition of two-stage skin carcinogenesis as well as complete skin carcinogenesis by oral administration of TMK688, a potent lipoxygenase inhibitor. Carcinogenesis 1994, 15 (5), 807-812.
    • (1994) Carcinogenesis , vol.15 , Issue.5 , pp. 807-812
    • Jiang, H.1    Yamamoto, S.2    Kato, R.3
  • 76
    • 84856229128 scopus 로고    scopus 로고
    • Genetic deletion of 5-lipoxygenase increases tumor-infiltrating macrophages in Apc(8468) mice
    • Cheon, E. C; Strouch, M. J.; Krantz, S. B.; Heiferman, M. J.; Bentrem, D. J. Genetic deletion of 5-lipoxygenase increases tumor-infiltrating macrophages in Apc(8468) mice. J. Gastrointest. Surg. 2012, 16 (2), 389-393.
    • (2012) J. Gastrointest. Surg , vol.16 , Issue.2 , pp. 389-393
    • Cheon, E.C.1    Strouch, M.J.2    Krantz, S.B.3    Heiferman, M.J.4    Bentrem, D.J.5
  • 77
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan, C. Nitric oxide and the immune response. Nat. Immunol. 2001, 2 (10), 907-916.
    • (2001) Nat. Immunol , vol.2 , Issue.10 , pp. 907-916
    • Bogdan, C.1
  • 78
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • Nathan, C; Xie, Q. W. Nitric oxide synthases: roles, tolls, and controls. Cell 1994, 78, 915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.W.2
  • 79
    • 0028818035 scopus 로고
    • Nitric oxide synthase: Expression and expressional control of the three isoforms
    • Forstermann, U.; Kleinert, H. Nitric oxide synthase: expression and expressional control of the three isoforms. Naunyn Schmiedebergs Arch. Pharmacol. 1995, 352, 351-364.
    • (1995) Naunyn Schmiedebergs Arch. Pharmacol , vol.352 , pp. 351-364
    • Forstermann, U.1    Kleinert, H.2
  • 80
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan, C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 1992, 6 (12), 3051-3064.
    • (1992) FASEB J , vol.6 , Issue.12 , pp. 3051-3064
    • Nathan, C.1
  • 81
    • 0031901747 scopus 로고    scopus 로고
    • Molecular biology of nitric oxide synthases
    • Geller, D. A.; Billiar, T. R. Molecular biology of nitric oxide synthases. Cancer Metastasis Rev. 1998, 17 (1), 7-23.
    • (1998) Cancer Metastasis Rev , vol.17 , Issue.1 , pp. 7-23
    • Geller, D.A.1    Billiar, T.R.2
  • 83
    • 4043165470 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis
    • Chen, T.; Stoner, G. D. Inducible nitric oxide synthase expression in N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis. Mol. Carcinog. 2004, 40, 232-240.
    • (2004) Mol. Carcinog , vol.40 , pp. 232-240
    • Chen, T.1    Stoner, G.D.2
  • 84
    • 0034829648 scopus 로고    scopus 로고
    • Nitric oxide in gastrointestinal epithelial cell carcinogenesis: Linking inflammation to oncogenesis
    • Jaiswal, M.; LaRusso, N. F.; Gores, G. J. Nitric oxide in gastrointestinal epithelial cell carcinogenesis: linking inflammation to oncogenesis. Am. J. Physiol. Gastrointest. Liver Physiol. 2001, 281, G626-G634.
    • (2001) Am. J. Physiol. Gastrointest. Liver Physiol , vol.281
    • Jaiswal, M.1    Larusso, N.F.2    Gores, G.J.3
  • 87
    • 0028873889 scopus 로고
    • Expression of nitric oxide synthase in human central nervous system tumors
    • Cobbs, C. S.; Brenmen, J. E.; Aldape, K. D.; Bredt, D. S.; Israel, M. A. Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res. 1995, 55, 727-730.
    • (1995) Cancer Res , vol.55 , pp. 727-730
    • Cobbs, C.S.1    Brenmen, J.E.2    Aldape, K.D.3    Bredt, D.S.4    Israel, M.A.5
  • 88
    • 0032528178 scopus 로고    scopus 로고
    • Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas
    • Wilson, K. T.; Fu, S.; Ramanujam, K. S.; Meltzer, S. J. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas. Cancer Res. 1998, 58, 2929-2934.
    • (1998) Cancer Res , vol.58 , pp. 2929-2934
    • Wilson, K.T.1    Fu, S.2    Ramanujam, K.S.3    Meltzer, S.J.4
  • 89
    • 0347753322 scopus 로고    scopus 로고
    • Up-regulation of inducible nitric oxide synthase in Helicobacter pylori-associated gastritis may represent an increased risk factor to develop gastric carcinoma of the intestinal type
    • Rieder, G.; Hofmann, J. A.; Hatz, R. A.; Stolte, M.; Enders, G. A. Up-regulation of inducible nitric oxide synthase in Helicobacter pylori-associated gastritis may represent an increased risk factor to develop gastric carcinoma of the intestinal type. Int. J. Med. Microbiol. 2003, 293, 403-412.
    • (2003) Int. J. Med. Microbiol , vol.293 , pp. 403-412
    • Rieder, G.1    Hofmann, J.A.2    Hatz, R.A.3    Stolte, M.4    Enders, G.A.5
  • 90
    • 0035164414 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (iNOS) expression and its prognostic value in prostate cancer
    • Aaltoma, S. H.; Lipponen, P. K.; Kosma, V. M. Inducible nitric oxide synthase (iNOS) expression and its prognostic value in prostate cancer. Anticancer Res. 2001, 21, 3101-3106.
    • (2001) Anticancer Res , vol.21 , pp. 3101-3106
    • Aaltoma, S.H.1    Lipponen, P.K.2    Kosma, V.M.3
  • 91
    • 0028218474 scopus 로고
    • Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis
    • Ohshima, H.; Bartsch, H. Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mutat. Res. 1994, 305, 253-264.
    • (1994) Mutat. Res , vol.305 , pp. 253-264
    • Ohshima, H.1    Bartsch, H.2
  • 93
    • 0007755935 scopus 로고    scopus 로고
    • Chemoprevention of colon cancer by iNOS specific and non-specific inhibitors: A safer colon cancer chemopreventive strategy
    • Rao, C. V.; Kawamori, T.; Hamid, R.; Simi, B.; Gambrell, B.; Reddy, B. S. Chemoprevention of colon cancer by iNOS specific and non-specific inhibitors: a safer colon cancer chemopreventive strategy. Proc. Am. Assoc. Cancer Res. 1998, 39, 197.
    • (1998) Proc. Am. Assoc. Cancer Res , vol.39 , pp. 197
    • Rao, C.V.1    Kawamori, T.2    Hamid, R.3    Simi, B.4    Gambrell, B.5    Reddy, B.S.6
  • 94
    • 0030901206 scopus 로고    scopus 로고
    • Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane
    • Takahashi, M.; Fukuda, K.; Ohata, T.; Sugimura, T.; Wakabayashi, K. Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane. Cancer Res. 1997, 57, 1233-1237.
    • (1997) Cancer Res , vol.57 , pp. 1233-1237
    • Takahashi, M.1    Fukuda, K.2    Ohata, T.3    Sugimura, T.4    Wakabayashi, K.5
  • 95
    • 15844376480 scopus 로고    scopus 로고
    • b-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate
    • Kohno, H.; Suzuki, R.; Sugie, S.; Tanaka, T. b-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate. Cancer Sci. 2005, 96, 69-76.
    • (2005) Cancer Sci , vol.96 , pp. 69-76
    • Kohno, H.1    Suzuki, R.2    Sugie, S.3    Tanaka, T.4
  • 96
    • 27944442806 scopus 로고    scopus 로고
    • Dextran sodium sulfate strongly promotes colorectal carcinogenesis in ApcMin/+ mice: Inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms
    • Tanaka, T.; Kohno, H.; Suzuki, R.; Hata, K.; Sugie, S.; Niho, N.; Sakano, K.; Takahashi, M.; Wakabayashi, K. Dextran sodium sulfate strongly promotes colorectal carcinogenesis in ApcMin/+ mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms. Int. J. Cancer 2006, 118, 25-34.
    • (2006) Int. J. Cancer , vol.118 , pp. 25-34
    • Tanaka, T.1    Kohno, H.2    Suzuki, R.3    Hata, K.4    Sugie, S.5    Niho, N.6    Sakano, K.7    Takahashi, M.8    Wakabayashi, K.9
  • 98
    • 0033969322 scopus 로고    scopus 로고
    • Inflammatory cytokines induce DNA damage and inhibit DNA repair in colonic carcinoma cells by a nitric oxide-dependent mechanism
    • Jaiswal, M.; LaRusso, N. F.; Burgart, L.; Gores, G. Inflammatory cytokines induce DNA damage and inhibit DNA repair in colonic carcinoma cells by a nitric oxide-dependent mechanism. Cancer Res. 2000, 60, 184-189.
    • (2000) Cancer Res , vol.60 , pp. 184-189
    • Jaiswal, M.1    Larusso, N.F.2    Burgart, L.3    Gores, G.4
  • 99
    • 0031925590 scopus 로고    scopus 로고
    • Role of angiogenesis and microcirculation in tumors
    • Fukumura, D.; Jain, R. Role of angiogenesis and microcirculation in tumors. Cancer Metastasis Rev. 1998, 17, 77-89.
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 77-89
    • Fukumura, D.1    Jain, R.2
  • 100
    • 0030475604 scopus 로고    scopus 로고
    • Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis
    • Landino, L. M.; Crews, B. C.; Timmons, M. D.; Morrow, J. D.; Marnett, L. J. Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis. PNAS. 1996, 93, 15069-15074.
    • (1996) PNAS , vol.93 , pp. 15069-15074
    • Landino, L.M.1    Crews, B.C.2    Timmons, M.D.3    Morrow, J.D.4    Marnett, L.J.5
  • 101
    • 25144490062 scopus 로고    scopus 로고
    • Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands
    • Kohno, H.; Suzuki, R.; Sugie, S.; Tanaka, T. Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands. BMC Cancer 2005, 5, 46.
    • (2005) BMC Cancer , vol.5 , pp. 46
    • Kohno, H.1    Suzuki, R.2    Sugie, S.3    Tanaka, T.4
  • 102
    • 34250886851 scopus 로고    scopus 로고
    • A specific inducible nitric oxide synthase inhibitor, ONO-1714 attenuates inflammation-related large bowel carcinogenesis in male ApcMin/+ mice
    • Kohno, H.; Takahashi, M.; Yasui, Y.; Suzuki, R.; Miyamoto, S.; Kamanaka, Y.; Naka, M.; Maruyama, T.; Wakabayashi, K.; Tanaka, T. A specific inducible nitric oxide synthase inhibitor, ONO-1714 attenuates inflammation-related large bowel carcinogenesis in male ApcMin/+ mice, Int. J. Cancer 2007, 121, 506-513.
    • (2007) Int. J. Cancer , vol.121 , pp. 506-513
    • Kohno, H.1    Takahashi, M.2    Yasui, Y.3    Suzuki, R.4    Miyamoto, S.5    Kamanaka, Y.6    Naka, M.7    Maruyama, T.8    Wakabayashi, K.9    Tanaka, T.10
  • 103
    • 1542399059 scopus 로고    scopus 로고
    • Nitric oxide induces expression of cyclooxygenase-2 in mouse skin through activation of NFkB
    • Chun, K. S.; Cha, H. H.; Shin, J. W.; Na, H. K.; Park, K. K.; Chung, W. Y.; Surh, Y. J. Nitric oxide induces expression of cyclooxygenase-2 in mouse skin through activation of NFkB, Carcinogenesis 2004, 25, 445-454.
    • (2004) Carcinogenesis , vol.25 , pp. 445-454
    • Chun, K.S.1    Cha, H.H.2    Shin, J.W.3    Na, H.K.4    Park, K.K.5    Chung, W.Y.6    Surh, Y.J.7
  • 104
    • 0036144387 scopus 로고    scopus 로고
    • Chemopreventive Properties of a Selective Inducible Nitric Oxide Synthase Inhibitor in Colon Carcinogenesis, Administered Alone or in Combination with Celecoxib, a Selective Cyclooxygenase-2 Inhibitor
    • Rao, C. V.; Indranie, C.; Simi, B.; Manning, P. T.; Connor, J. R.; Reddy, B. S. Chemopreventive Properties of a Selective Inducible Nitric Oxide Synthase Inhibitor in Colon Carcinogenesis, Administered Alone or in Combination with Celecoxib, a Selective Cyclooxygenase-2 Inhibitor. Cancer Res. 2002, 62, 165-170.
    • (2002) Cancer Res , vol.62 , pp. 165-170
    • Rao, C.V.1    Indranie, C.2    Simi, B.3    Manning, P.T.4    Connor, J.R.5    Reddy, B.S.6
  • 105
    • 85007652699 scopus 로고    scopus 로고
    • Chemo-prevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor
    • Rao, C. V.; Kawamori, T.; Hamid, R.; Reddy, B. S. Chemo-prevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor. Carcinogenesis 2000, 21, 617-621.
    • (2000) Carcinogenesis , vol.21 , pp. 617-621
    • Rao, C.V.1    Kawamori, T.2    Hamid, R.3    Reddy, B.S.4
  • 106
    • 0030877443 scopus 로고    scopus 로고
    • Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: Studies with 1400W, a novel inhibitor
    • Thomsen, L. L.; Scott, J. M.; Topley, P.; Knowles, R. G.; Keerie, A. J.; Frend, A. J. Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor. Cancer Res. 1997, 57 (15), 3300-3304.
    • (1997) Cancer Res , vol.57 , Issue.15 , pp. 3300-3304
    • Thomsen, L.L.1    Scott, J.M.2    Topley, P.3    Knowles, R.G.4    Keerie, A.J.5    Frend, A.J.6
  • 107
    • 0036005888 scopus 로고    scopus 로고
    • Tumor necrosis factor or tumor promoting factor?
    • Balkwill, F. Tumor necrosis factor or tumor promoting factor? Cytokine Growth Factor Rev. 2002, 13 (2), 135-141.
    • (2002) Cytokine Growth Factor Rev , vol.13 , Issue.2 , pp. 135-141
    • Balkwill, F.1
  • 108
    • 24344479304 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha confers an invasive, transformed phenotype on mammary epithelial cells
    • Montesano, R.; Soulie, P.; Eble, J. A.; Carrozzino, F. Tumour necrosis factor alpha confers an invasive, transformed phenotype on mammary epithelial cells. J. Cell Sci. 2005, 118 (15), 3487-3500.
    • (2005) J. Cell Sci , vol.118 , Issue.15 , pp. 3487-3500
    • Montesano, R.1    Soulie, P.2    Eble, J.A.3    Carrozzino, F.4
  • 109
    • 0027515621 scopus 로고
    • Inverse regulation of human ERBB2 and epidermal growth factor receptors by tumor necrosis factor alpha
    • Kalthoff, H.; Roeder, C.; Gieseking, J.; Humburg, I.; Schmiegel, W. Inverse regulation of human ERBB2 and epidermal growth factor receptors by tumor necrosis factor alpha. PNAS. 1993, 90 (19), 8972-8976.
    • (1993) PNAS , vol.90 , Issue.19 , pp. 8972-8976
    • Kalthoff, H.1    Roeder, C.2    Gieseking, J.3    Humburg, I.4    Schmiegel, W.5
  • 110
    • 0032577708 scopus 로고    scopus 로고
    • Constitutive activation of NFkappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role oftumor necrosis factor and reactive oxygen intermediates
    • Giri, D. K.; Aggarwal, B. B. Constitutive activation of NFkappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role oftumor necrosis factor and reactive oxygen intermediates. J. Biol. Chem. 1998, 273 (22), 14008-14014.
    • (1998) J. Biol. Chem , vol.273 , Issue.22 , pp. 14008-14014
    • Giri, D.K.1    Aggarwal, B.B.2
  • 111
    • 0032523843 scopus 로고    scopus 로고
    • The role of type I and type II tumor necrosis factor (TNF) receptors in the ability of TNF-alpha to transduce a proliferative signal in the human megakaryoblastic leukemic cell line Mo7e
    • Liu, R. Y.; Fan, C.; Mitchell, S.; Chen, Q.; Wu, J.; Zuckerman, K. S. The role of type I and type II tumor necrosis factor (TNF) receptors in the ability of TNF-alpha to transduce a proliferative signal in the human megakaryoblastic leukemic cell line Mo7e. Cancer Res. 1998, 58 (10), 2217-2223.
    • (1998) Cancer Res , vol.58 , Issue.10 , pp. 2217-2223
    • Liu, R.Y.1    Fan, C.2    Mitchell, S.3    Chen, Q.4    Wu, J.5    Zuckerman, K.S.6
  • 112
    • 0027393655 scopus 로고
    • Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells
    • Schmiegel, W.; Roeder, C.; Schmielau, J.; Rodeck, U.; Kalthoff, H. Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells. PNAS. 1993, 90 (3), 863-867.
    • (1993) PNAS , vol.90 , Issue.3 , pp. 863-867
    • Schmiegel, W.1    Roeder, C.2    Schmielau, J.3    Rodeck, U.4    Kalthoff, H.5
  • 114
  • 116
    • 0023199833 scopus 로고
    • The in vivo effects of interleukin 1. I. Bone marrow cells are induced to cycle after administration of interleukin 1
    • Neta, R.; Sztein, M. B.; Oppenheim, J. J.; Gillis, S.; Douches, S. D. The in vivo effects of interleukin 1. I. Bone marrow cells are induced to cycle after administration of interleukin 1. J. Immunol. 1987, 139, 1861-1866.
    • (1987) J. Immunol , vol.139 , pp. 1861-1866
    • Neta, R.1    Sztein, M.B.2    Oppenheim, J.J.3    Gillis, S.4    Douches, S.D.5
  • 117
    • 0028339564 scopus 로고
    • Autocrine regulation of ICAM-1 expression on bladder cancer cell lines: Evidence for the role of IL-1 alpha
    • Alexandroff, A. B.; Jackson, A. M.; Esuvaranathan, K.; Prescott, S.; James, K. Autocrine regulation of ICAM-1 expression on bladder cancer cell lines: evidence for the role of IL-1 alpha. Immunol. Lett. 1994, 40, 117-124.
    • (1994) Immunol. Lett , vol.40 , pp. 117-124
    • Alexandroff, A.B.1    Jackson, A.M.2    Esuvaranathan, K.3    Prescott, S.4    James, K.5
  • 118
    • 0028150982 scopus 로고
    • Host-tumor interaction in ovarian cancer. Spontaneous release of tumor necrosis factor and interleukin-1 inhibitors by purified cell populations from human ovarian carcinoma in vitro
    • Burger, R. A.; Grosen, E. A.; Ioli, G. R.; Van Eden, M. E.; Brightbill, H. D.; Gatanaga, M.; Disaia, P. J.; Granger, G. A.; Gatanaga, T. Host-tumor interaction in ovarian cancer. Spontaneous release of tumor necrosis factor and interleukin-1 inhibitors by purified cell populations from human ovarian carcinoma in vitro. Gynecol. Oncol. 1994, 55, 294-303.
    • (1994) Gynecol. Oncol , vol.55 , pp. 294-303
    • Burger, R.A.1    Grosen, E.A.2    Ioli, G.R.3    van Eden, M.E.4    Brightbill, H.D.5    Gatanaga, M.6    Disaia, P.J.7    Granger, G.A.8    Gatanaga, T.9
  • 119
    • 0028169370 scopus 로고
    • Expression of interleukin 1 alpha, interleukin 6, and tumor necrosis factor alpha genes in human melanoma clones is associated with that of mutated N-RAS oncogene
    • Castelli, C; Sensi, M.; Lupetti, R.; Mortarini, R.; Panceri, P.; Anichini, A.; Parmiani, G. Expression of interleukin 1 alpha, interleukin 6, and tumor necrosis factor alpha genes in human melanoma clones is associated with that of mutated N-RAS oncogene. Cancer Res. 1994, 54, 4785-4790.
    • (1994) Cancer Res , vol.54 , pp. 4785-4790
    • Castelli, C.1    Sensi, M.2    Lupetti, R.3    Mortarini, R.4    Panceri, P.5    Anichini, A.6    Parmiani, G.7
  • 122
    • 0036694589 scopus 로고    scopus 로고
    • IL-6 in autoimmune disease and chronic inflammatory proliferative disease
    • Ishihara, K.; Hirano, T. IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev. 2002, 13, 357-368.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 357-368
    • Ishihara, K.1    Hirano, T.2
  • 123
    • 33744719480 scopus 로고    scopus 로고
    • Inhibition of IL-1, IL-6, and TNF-alpha in immune-mediated inflammatory diseases
    • Moller, B.; Villiger, P. M. Inhibition of IL-1, IL-6, and TNF-alpha in immune-mediated inflammatory diseases. Springer Semin. Immunopathol. 2006, 27, 391-408.
    • (2006) Springer Semin. Immunopathol , vol.27 , pp. 391-408
    • Moller, B.1    Villiger, P.M.2
  • 124
    • 3342892420 scopus 로고    scopus 로고
    • Inhibition of IL-6 for the treatment of inflammatory diseases
    • Nishimoto, N.; Kishimoto, T. Inhibition of IL-6 for the treatment of inflammatory diseases.Curr. Opin. Pharmacol. 2004, 4, 386-391.
    • (2004) Curr. Opin. Pharmacol , vol.4 , pp. 386-391
    • Nishimoto, N.1    Kishimoto, T.2
  • 125
    • 33746378638 scopus 로고    scopus 로고
    • Signalling and survival pathways in multiple myeloma
    • Bommert, K.; Bargou, R. C; Stuhmer, T. Signalling and survival pathways in multiple myeloma. Eur. J. Cancer 2006, 42, 1574-1580.
    • (2006) Eur. J. Cancer , vol.42 , pp. 1574-1580
    • Bommert, K.1    Bargou, R.C.2    Stuhmer, T.3
  • 127
    • 0032703834 scopus 로고    scopus 로고
    • KSHV-encoded viral IL-6 activates multiple human IL-6 signaling pathways
    • Osborne, J.; Moore, P. S.; Chang, Y. KSHV-encoded viral IL-6 activates multiple human IL-6 signaling pathways. Hum. Immunol. 1999, 60 (10), 921-927.
    • (1999) Hum. Immunol , vol.60 , Issue.10 , pp. 921-927
    • Osborne, J.1    Moore, P.S.2    Chang, Y.3
  • 129
    • 84863172276 scopus 로고    scopus 로고
    • Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis
    • Yamada, H. Y.; Yao, Y.; Wang, X.; Zhang, Y.; Huang, Y.; Dai, W.; Rao, C. V. Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis. Cell Cycle 2012, 11 (3), 479-488.
    • (2012) Cell Cycle , vol.11 , Issue.3 , pp. 479-488
    • Yamada, H.Y.1    Yao, Y.2    Wang, X.3    Zhang, Y.4    Huang, Y.5    Dai, W.6    Rao, C.V.7
  • 131
    • 1942469354 scopus 로고    scopus 로고
    • Identification of an autoregulatory feedback pathway involving interleukin-1 alpha in induction of constitutive NF-kappaB activation in pancreatic cancer cells
    • Niu, J.; Li, Z.; Peng, B.; Chiao, P. J. Identification of an autoregulatory feedback pathway involving interleukin-1 alpha in induction of constitutive NF-kappaB activation in pancreatic cancer cells. J. Biol. Chem. 2004, 279 (16), 16452-16456.
    • (2004) J. Biol. Chem , vol.279 , Issue.16 , pp. 16452-16456
    • Niu, J.1    Li, Z.2    Peng, B.3    Chiao, P.J.4
  • 132
    • 0347334750 scopus 로고    scopus 로고
    • IL-1betamediated up-regulation of HIF-1alpha via an NfkappaB/ COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
    • Jung, Y. J.; Isaacs, J. S.; Lee, S.; Trepel, J.; Neckers, L. IL-1betamediated up-regulation of HIF-1alpha via an NfkappaB/ COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J. 2003, 17 (14), 2115-2117.
    • (2003) FASEB J , vol.17 , Issue.14 , pp. 2115-2117
    • Jung, Y.J.1    Isaacs, J.S.2    Lee, S.3    Trepel, J.4    Neckers, L.5
  • 133
    • 0038079807 scopus 로고    scopus 로고
    • Bellvitge Colorectal Cancer Study Group. Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFkB1, and peroxisome proliferatoractivated receptor gamma with colorectal cancer
    • Landi, S.; Moreno, V.; Gioia-Patricola, L.; Guino, E.; Navarro, M.; de Oca, J.; Capella, G.; Canzian, F. Bellvitge Colorectal Cancer Study Group. Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFkB1, and peroxisome proliferatoractivated receptor gamma with colorectal cancer. Cancer Res. 2003, 63 (13), 3560-3566.
    • (2003) Cancer Res , vol.63 , Issue.13 , pp. 3560-3566
    • Landi, S.1    Moreno, V.2    Gioia-Patricola, L.3    Guino, E.4    Navarro, M.5    de Oca, J.6    Capella, G.7    Canzian, F.8
  • 135
    • 0036310021 scopus 로고    scopus 로고
    • Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma
    • Huang, S.; Mills, L.; Mian, B.; Tellez, C; McCarty, M.; Yang, X. D.; Gudas, J. M.; Bar-Eli, M. Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma. Am. J. Pathol. 2002, 161 (1), 125-134.
    • (2002) Am. J. Pathol , vol.161 , Issue.1 , pp. 125-134
    • Huang, S.1    Mills, L.2    Mian, B.3    Tellez, C.4    McCarty, M.5    Yang, X.D.6    Gudas, J.M.7    Bar-Eli, M.8
  • 136
    • 18044402080 scopus 로고    scopus 로고
    • Leukemia stem cells and constitutive activation of NFkB
    • Griffin, J. D. Leukemia stem cells and constitutive activation of NFkB. Blood 2001, 98, 2291.
    • (2001) Blood , vol.98 , pp. 2291
    • Griffin, J.D.1
  • 137
    • 0033517999 scopus 로고    scopus 로고
    • Constitutive activation of IkB kinase a and NFkB in prostate cancer cells is inhibited by ibuprofen
    • Palayoor, S. T.; Youmell, M. Y.; Calderwood, S. K.; Coleman, C. N.; Price, B. D. Constitutive activation of IkB kinase a and NFkB in prostate cancer cells is inhibited by ibuprofen. Oncogene 1999, 18, 7389-7394.
    • (1999) Oncogene , vol.18 , pp. 7389-7394
    • Palayoor, S.T.1    Youmell, M.Y.2    Calderwood, S.K.3    Coleman, C.N.4    Price, B.D.5
  • 138
    • 0030927167 scopus 로고    scopus 로고
    • Constitutive activation of NFkB during progression of breast cancer to hormone-independent growth
    • Nakshatri, H.; Bhat-Nakshatri, P.; Martin, D. A.; Goulet, R. J. Jr.; Sledge, G. W. Jr. Constitutive activation of NFkB during progression of breast cancer to hormone-independent growth. Mol. Cell. Biol. 1997, 17, 3629-3639.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 3629-3639
    • Nakshatri, H.1    Bhat-Nakshatri, P.2    Martin, D.A.3    Goulet Jr., R.J.4    Sledge Jr., G.W.5
  • 139
    • 0033015706 scopus 로고    scopus 로고
    • Transcriptional up-regulation of matrix metalloproteinase9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor kB elements
    • Farina, A. R.; Tacconelli, A.; Vacca, A.; Maroder, M.; Gulino, A.; Mackay, A. R. Transcriptional up-regulation of matrix metalloproteinase9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor kB elements. Cell Growth Differ. 1999, 10, 353-367.
    • (1999) Cell Growth Differ , vol.10 , pp. 353-367
    • Farina, A.R.1    Tacconelli, A.2    Vacca, A.3    Maroder, M.4    Gulino, A.5    Mackay, A.R.6
  • 140
    • 0032508674 scopus 로고    scopus 로고
    • Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: An absolute requirement for transcription factor NFkB
    • Bond, M.; Fabunmi, R. P.; Baker, A. H.; Newby, A. C. Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: An absolute requirement for transcription factor NFkB. FEBS Lett. 1998, 435, 29-34.
    • (1998) FEBS Lett , vol.435 , pp. 29-34
    • Bond, M.1    Fabunmi, R.P.2    Baker, A.H.3    Newby, A.C.4
  • 141
    • 0025899613 scopus 로고
    • A labile repressor acts through the NFKB-like binding sites of the human urokinase gene
    • Novak, U.; Cocks, B. G.; Hamilton, J. A. A labile repressor acts through the NFKB-like binding sites of the human urokinase gene. Nucleic Acids Res. 1991, 19, 3389-3393.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3389-3393
    • Novak, U.1    Cocks, B.G.2    Hamilton, J.A.3
  • 142
    • 0027992051 scopus 로고
    • 12-Otetradecanoylphorbol-13-acetate- and tumor necrosis factor a-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter
    • Van de Stolpe, A.; Caldenhoven, E.; Stade, B. G.; Koenderman, L.; Raaijmakers, J. A.; Johnson, J. P.; van der Saag, P. T. 12-Otetradecanoylphorbol-13-acetate- and tumor necrosis factor a-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter. J. Biol. Chem. 1994, 269, 6185-6192.
    • (1994) J. Biol. Chem , vol.269 , pp. 6185-6192
    • Van de Stolpe, A.1    Caldenhoven, E.2    Stade, B.G.3    Koenderman, L.4    Raaijmakers, J.A.5    Johnson, J.P.6    van der Saag, P.T.7
  • 146
    • 79956080227 scopus 로고    scopus 로고
    • Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2
    • Nagendraprabhu, P.; Sudhandiran G. Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2. Invest New Drugs. 2011, 29 (2), 207-224.
    • (2011) Invest New Drugs , vol.29 , Issue.2 , pp. 207-224
    • Nagendraprabhu, P.1    Sudhandiran, G.2
  • 147
    • 77954730556 scopus 로고    scopus 로고
    • Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1,2-dimethylhydrazine-induced rat colon carcinogenesis
    • Umesalma, S.; Sudhandiran G. Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Basic Clin. Pharmacol. Toxicol. 2010, 107 (2), 650-655.
    • (2010) Basic Clin. Pharmacol. Toxicol , vol.107 , Issue.2 , pp. 650-655
    • Umesalma, S.1    Sudhandiran, G.2
  • 148
    • 0028872989 scopus 로고
    • Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound
    • Rao, C. V.; Rivenson, A.; Simi, B.; Reddy, B. S. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res. 1995, 55 (2), 259-266.
    • (1995) Cancer Res , vol.55 , Issue.2 , pp. 259-266
    • Rao, C.V.1    Rivenson, A.2    Simi, B.3    Reddy, B.S.4
  • 149
    • 8644238077 scopus 로고    scopus 로고
    • Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells
    • Pradeep, C. R.; Kuttan, G. Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells. Int. Immunopharmacol. 2004, 4, 1795-1803.
    • (2004) Int. Immunopharmacol , vol.4 , pp. 1795-1803
    • Pradeep, C.R.1    Kuttan, G.2
  • 150
    • 4043124898 scopus 로고    scopus 로고
    • Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells
    • Raju, J.; Malisetty, V. S.; Patlolla, J. M. R.; Rao, C. V. Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells. Cancer Epidemiol. Biomarkers Prev. 2004, 13, 1392-1398.
    • (2004) Cancer Epidemiol. Biomarkers Prev , vol.13 , pp. 1392-1398
    • Raju, J.1    Malisetty, V.S.2    Patlolla, J.M.R.3    Rao, C.V.4
  • 151
    • 49549117555 scopus 로고    scopus 로고
    • Chemoprevention of colon carcinogenesis by oleanolic acid and its analog in male F344 rats and modulation of COX-2 and apoptosis in human colon HT-29 cancer cells
    • Janakiram, N. B.; Indranie, C.; Malisetty, S. V.; Jagan, P.; Steele, V. E.; Rao, C. V. Chemoprevention of colon carcinogenesis by oleanolic acid and its analog in male F344 rats and modulation of COX-2 and apoptosis in human colon HT-29 cancer cells. Pharm. Res. 2008, 25 (9), 2151-2157.
    • (2008) Pharm. Res , vol.25 , Issue.9 , pp. 2151-2157
    • Janakiram, N.B.1    Indranie, C.2    Malisetty, S.V.3    Jagan, P.4    Steele, V.E.5    Rao, C.V.6
  • 152
    • 0008910975 scopus 로고
    • A preliminary report on anti inflammatory activity of curcumin
    • Srimal, R. C.; Khanna, N. M.; Dhawan, B. N. A preliminary report on anti inflammatory activity of curcumin. Int. J. Pharm. 1971, 3, 10-13.
    • (1971) Int. J. Pharm , vol.3 , pp. 10-13
    • Srimal, R.C.1    Khanna, N.M.2    Dhawan, B.N.3
  • 153
    • 0020450453 scopus 로고
    • Anti-inflammatory and irritant activities of curcumin analogues in rats
    • Mukhopadhyay, A.; Basu, N.; Ghatak, N. Anti-inflammatory and irritant activities of curcumin analogues in rats. Agents Actions 1982, 12, 508-515.
    • (1982) Agents Actions , vol.12 , pp. 508-515
    • Mukhopadhyay, A.1    Basu, N.2    Ghatak, N.3
  • 154
    • 0022972545 scopus 로고
    • Evaluation of anti-inflammatory property of curcumin in patients with postoperative inflammation
    • Satoskar, R. R.; Shah, S. J.; Shenoy, S. G. Evaluation of anti-inflammatory property of curcumin in patients with postoperative inflammation. Int. J. Clin. Pharmacol. Ther. Toxicol. 1986, 24, 651-654.
    • (1986) Int. J. Clin. Pharmacol. Ther. Toxicol , vol.24 , pp. 651-654
    • Satoskar, R.R.1    Shah, S.J.2    Shenoy, S.G.3
  • 155
    • 13244289773 scopus 로고    scopus 로고
    • Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: Mechanism of free radical scavenging activity
    • Biswas, S. K.; McClure, D.; Jimenez, L. A.; Megson, I. L.; Rahman, I. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: Mechanism of free radical scavenging activity. Antioxid. Redox. Signal. 2005, 7, 32-41.
    • (2005) Antioxid. Redox. Signal , vol.7 , pp. 32-41
    • Biswas, S.K.1    McClure, D.2    Jimenez, L.A.3    Megson, I.L.4    Rahman, I.5
  • 156
    • 0027333082 scopus 로고
    • Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon
    • Rao, C. V.; Simi, B.; Reddy, B. S. Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon. Carcinogenesis 1993, 14 (11), 2219-2225.
    • (1993) Carcinogenesis , vol.14 , Issue.11 , pp. 2219-2225
    • Rao, C.V.1    Simi, B.2    Reddy, B.S.3
  • 157
    • 0033082458 scopus 로고    scopus 로고
    • Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer
    • Kawamori, T.; Lubet, R.; Steele, V. E.; Kelloff, G. J.; Kaskey, R. B.; Rao, C. V.; Reddy, B. S. Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res. 1999, 59(3), 597-601.
    • (1999) Cancer Res , vol.59 , Issue.3 , pp. 597-601
    • Kawamori, T.1    Lubet, R.2    Steele, V.E.3    Kelloff, G.J.4    Kaskey, R.B.5    Rao, C.V.6    Reddy, B.S.7
  • 159
    • 34247232597 scopus 로고    scopus 로고
    • Celecoxib and curcumin additively inhibit the growth of colorectal cancer in a rat model
    • Shpitz, B.; Giladi, N.; Sagiv, E.; Lev-Ari, S.; Liberman, E.; Kazanov, D.; Arber, N. Celecoxib and curcumin additively inhibit the growth of colorectal cancer in a rat model. Digestion 2006, 74 (3-4), 140-144.
    • (2006) Digestion , vol.74 , Issue.3-4 , pp. 140-144
    • Shpitz, B.1    Giladi, N.2    Sagiv, E.3    Lev-Ari, S.4    Liberman, E.5    Kazanov, D.6    Arber, N.7
  • 160
    • 72149121289 scopus 로고    scopus 로고
    • Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis
    • Xu, G.; Ren, G.; Xu, X.; Yuan, H.; Wang, Z.; Kang, L.; Yu, W.; Tian, K. Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis. Food Chem. Toxicol. 2010, 48 (1), 390-395.
    • (2010) Food Chem. Toxicol , vol.48 , Issue.1 , pp. 390-395
    • Xu, G.1    Ren, G.2    Xu, X.3    Yuan, H.4    Wang, Z.5    Kang, L.6    Yu, W.7    Tian, K.8
  • 161
    • 0035085606 scopus 로고    scopus 로고
    • Piperine inhibits gastric emptying and gastro-intestinal tansit in rats and mice
    • Bajad, S.; Bedi, K.L.; Singla, A. K.; Johri, R. K. Piperine inhibits gastric emptying and gastro-intestinal tansit in rats and mice. Planta Med. 2001, 67, 176-179.
    • (2001) Planta Med , vol.67 , pp. 176-179
    • Bajad, S.1    Bedi, K.L.2    Singla, A.K.3    Johri, R.K.4
  • 162
    • 0036250151 scopus 로고    scopus 로고
    • Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: Influence on brush border membrane fluidity, ultrastructure and enzyme kinetics
    • Khajuria, A.; Thusu, N.; Zutshi, U. Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: Influence on brush border membrane fluidity, ultrastructure and enzyme kinetics. Phytomedicine 2002, 9, 224-231.
    • (2002) Phytomedicine , vol.9 , pp. 224-231
    • Khajuria, A.1    Thusu, N.2    Zutshi, U.3
  • 163
    • 0021931513 scopus 로고
    • Biochemical basis of enhanced drug bioavailability of piperine: Evidence that piperine is a potent inhibitor of drug metabolism
    • Atal, C. K.; Dubey, R. K.; Singh, J. Biochemical basis of enhanced drug bioavailability of piperine: evidence that piperine is a potent inhibitor of drug metabolism. J. Pharmacol. Exp. Ther. 1985, 232, 258-262.
    • (1985) J. Pharmacol. Exp. Ther , vol.232 , pp. 258-262
    • Atal, C.K.1    Dubey, R.K.2    Singh, J.3
  • 165
    • 0033847147 scopus 로고    scopus 로고
    • Invitro antioxidant activity of piperine
    • Mittal, R.; Gupta, R. L. Invitro antioxidant activity of piperine. Exp. Clin. Pharmacol. 2000, 22, 271-274.
    • (2000) Exp. Clin. Pharmacol , vol.22 , pp. 271-274
    • Mittal, R.1    Gupta, R.L.2
  • 166
    • 0141564742 scopus 로고    scopus 로고
    • Effect of piperine on the production of nitric oxide and TNF-a In vitro as well as in vivo
    • Pradeep, C. R.; Kuttan, G. Effect of piperine on the production of nitric oxide and TNF-a In vitro as well as in vivo. Immuno-pharmacol. Immunotoxicol. 1999, 25, 337-346.
    • (1999) Immuno-pharmacol. Immunotoxicol , vol.25 , pp. 337-346
    • Pradeep, C.R.1    Kuttan, G.2
  • 167
    • 0036939104 scopus 로고    scopus 로고
    • Effect of piperine on the inhibition of lung metastasis induced B16F-10 melanoma cells in mice
    • Pradeep, C. R.; Kuttan, G. Effect of piperine on the inhibition of lung metastasis induced B16F-10 melanoma cells in mice. Clin. Exp. Metastasis 2002, 19, 703-708.
    • (2002) Clin. Exp. Metastasis , vol.19 , pp. 703-708
    • Pradeep, C.R.1    Kuttan, G.2
  • 168
    • 17244367032 scopus 로고    scopus 로고
    • Chemopreventive effect of piperine on mitochondrial TCA cycle and phase-I and glutathione-metabolizing enzymes in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice
    • Selvendiran, K.; Thirunavukkarasu, C.; Singh, J. P.; Padmavathi, R.; Sakthisekaran, D. Chemopreventive effect of piperine on mitochondrial TCA cycle and phase-I and glutathione-metabolizing enzymes in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. Mol. Cell Biochem. 2005, 271 (1-2), 101-106.
    • (2005) Mol. Cell Biochem , vol.271 , Issue.1-2 , pp. 101-106
    • Selvendiran, K.1    Thirunavukkarasu, C.2    Singh, J.P.3    Padmavathi, R.4    Sakthisekaran, D.5
  • 169
    • 14244265798 scopus 로고    scopus 로고
    • Oral supplementation of piperine leads to altered phase II enzymes and reduced DNA damage and DNA-protein cross links in Benzo(a)pyrene induced experimental lung carcinogenesis
    • Selvendiran, K.; Banu, S. M.; Sakthisekaran, D. Oral supplementation of piperine leads to altered phase II enzymes and reduced DNA damage and DNA-protein cross links in Benzo(a)pyrene induced experimental lung carcinogenesis. Mol. Cell Biochem. 2005, 268 (1-2), 141-147.
    • (2005) Mol. Cell Biochem , vol.268 , Issue.1-2 , pp. 141-147
    • Selvendiran, K.1    Banu, S.M.2    Sakthisekaran, D.3
  • 171
    • 33745822475 scopus 로고    scopus 로고
    • Effect of spices on lipid metabolism in 1,2-dimethylhydrazine-induced rat colon carcinogenesis
    • Nalini, N.; Manju, V.; Menon, V. P. Effect of spices on lipid metabolism in 1,2-dimethylhydrazine-induced rat colon carcinogenesis. J. Med. Food 2006, 9, 237-245.
    • (2006) J. Med. Food , vol.9 , pp. 237-245
    • Nalini, N.1    Manju, V.2    Menon, V.P.3
  • 172
    • 2942529470 scopus 로고    scopus 로고
    • Chemopreventive effect of piperine on modulating lipid peroxidation and membrane bound enzymes in benzo(alpha)pyrene induced lung carcinogenesis
    • Selvendiran, K.; Sakthisekaran, D. Chemopreventive effect of piperine on modulating lipid peroxidation and membrane bound enzymes in benzo(alpha)pyrene induced lung carcinogenesis. Biomed. Pharmacother. 2004, 58, 264-267.
    • (2004) Biomed. Pharmacother , vol.58 , pp. 264-267
    • Selvendiran, K.1    Sakthisekaran, D.2
  • 173
    • 65649094776 scopus 로고    scopus 로고
    • Growth inhibition of human colon cancer cells by plant compounds
    • Duessel, S.; Heuertz, R. M.; Ezekiel, U. R. Growth inhibition of human colon cancer cells by plant compounds. Clin. Lab Sci. 2008, 21 (3), 151-157.
    • (2008) Clin. Lab Sci , vol.21 , Issue.3 , pp. 151-157
    • Duessel, S.1    Heuertz, R.M.2    Ezekiel, U.R.3
  • 174
    • 77956710834 scopus 로고    scopus 로고
    • Inhibitory effects of black pepper (Piper nigrum) extracts and compounds on human tumor cell proliferation, cyclooxygenase enzymes, lipid peroxidation and nuclear transcription factor-kappa-B
    • Liu, Y.; Yadev, V. R.; Aggarwal, B. B.; Nair, M. G. Inhibitory effects of black pepper (Piper nigrum) extracts and compounds on human tumor cell proliferation, cyclooxygenase enzymes, lipid peroxidation and nuclear transcription factor-kappa-B. Nat. Prod. Commun. 2010, 5 (8), 1253-1257.
    • (2010) Nat. Prod. Commun , vol.5 , Issue.8 , pp. 1253-1257
    • Liu, Y.1    Yadev, V.R.2    Aggarwal, B.B.3    Nair, M.G.4
  • 175
    • 80053566053 scopus 로고    scopus 로고
    • Combined effects of curcumin and piperine in ameliorating benzo(a)pyrene induced DNA damage
    • Sehgal, A.; Kumar, M.; Jain, M.; Dhawan D. K. Combined effects of curcumin and piperine in ameliorating benzo(a)pyrene induced DNA damage. Food Chem. Toxicol. 2011, 49 (11), 3002-3006.
    • (2011) Food Chem. Toxicol , vol.49 , Issue.11 , pp. 3002-3006
    • Sehgal, A.1    Kumar, M.2    Jain, M.3    Dhawan, D.K.4
  • 176
    • 0035523777 scopus 로고    scopus 로고
    • Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: A double blind placebo controlled study
    • Gupta, A.; Gupta, R.; Lal, B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J. Assoc. Physicians India 2001, 49, 1057-1061.
    • (2001) J. Assoc. Physicians India , vol.49 , pp. 1057-1061
    • Gupta, A.1    Gupta, R.2    Lal, B.3
  • 177
    • 0035996883 scopus 로고    scopus 로고
    • Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats
    • Pandian, R. S.; Anuradha, C. V.; Viswanathan, P. Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats. J. Ethnopharmacol. 2002, 81 (3), 393-397.
    • (2002) J. Ethnopharmacol , vol.81 , Issue.3 , pp. 393-397
    • Pandian, R.S.1    Anuradha, C.V.2    Viswanathan, P.3
  • 178
    • 0026036209 scopus 로고
    • Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek
    • Sauvaire, Y.; Ribes, G.; Baccou, J. C.; Loubatieères-Mariani, M. M. Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. Lipids 1991, 26 (3), 191-197.
    • (1991) Lipids , vol.26 , Issue.3 , pp. 191-197
    • Sauvaire, Y.1    Ribes, G.2    Baccou, J.C.3    Loubatieères-Mariani, M.M.4
  • 179
    • 0345583507 scopus 로고    scopus 로고
    • New York (NY): Dorling Kindersley Publishing, Inc
    • Chevallier, A. 2000, Encyclopedia of herbal medicine. New York (NY): Dorling Kindersley Publishing, Inc, 271.
    • (2000) Encyclopedia of Herbal Medicine , pp. 271
    • Chevallier, A.1
  • 181
    • 0034740870 scopus 로고    scopus 로고
    • Trigonella foenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes
    • Raju, J.; Gupta, D.; Rao, A. R.; Yadava, P. K.; Baquer, N. Z. Trigonella foenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes. Mol. Cell Biochem. 2001, 224, 45-51.
    • (2001) Mol. Cell Biochem , vol.224 , pp. 45-51
    • Raju, J.1    Gupta, D.2    Rao, A.R.3    Yadava, P.K.4    Baquer, N.Z.5
  • 182
    • 0033929847 scopus 로고    scopus 로고
    • Medicinal foodstuffs. XVII. Fenugreek seed (3): Structures of new furostanol-type steroid saponins, trigoneosides Xa, Xb, XIb, XIIa, XIIb, and XIIIa, from the seeds of Egyptian Trigonella foenum graecum L. Chem. Pharm. Bull
    • Murakami, T.; Kishi, A.; Matsuda, H.; Yoshikawa, M. Medicinal foodstuffs. XVII. Fenugreek seed (3): structures of new furostanol-type steroid saponins, trigoneosides Xa, Xb, XIb, XIIa, XIIb, and XIIIa, from the seeds of Egyptian Trigonella foenum graecum L. Chem. Pharm. Bull (Tokyo), 2000, 48, 994-1000.
    • (2000) Trigonella foenum graecum L. Chem. Pharm. Bull (Tokyo) , vol.48 , pp. 994-1000
    • Murakami, T.1    Kishi, A.2    Matsuda, H.3    Yoshikawa, M.4
  • 183
    • 0031013863 scopus 로고    scopus 로고
    • Medicinal foodstuffs. IV. Fenugreek seed (1): Structures of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, new furostanol saponins from the seeds of Indian Trigonella foenum graecum L
    • Yoshikawa, M.; Murakami, T.; Komatsu, H.; Murakami, N.; Yamahara, J.; Matsuda, H. Medicinal foodstuffs. IV. Fenugreek seed (1): structures of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, new furostanol saponins from the seeds of Indian Trigonella foenum graecum L. Chem. Pharm. Bull (Tokyo) 1997, 45, 81-87.
    • (1997) Chem. Pharm. Bull (Tokyo) , vol.45 , pp. 81-87
    • Yoshikawa, M.1    Murakami, T.2    Komatsu, H.3    Murakami, N.4    Yamahara, J.5    Matsuda, H.6
  • 185
    • 0035850836 scopus 로고    scopus 로고
    • A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells
    • Moalic, S.; Liagre, B.; Corbière, C.; Bianchi, A.; Dauça, M.; Bordji, K.; Beneytout, J. L. A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells. FEBS Lett. 2001, 506(3), 225-230.
    • (2001) FEBS Lett , vol.506 , Issue.3 , pp. 225-230
    • Moalic, S.1    Liagre, B.2    Corbière, C.3    Bianchi, A.4    Dauça, M.5    Bordji, K.6    Beneytout, J.L.7
  • 186
    • 77951908366 scopus 로고    scopus 로고
    • Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells
    • Li, F.; Fernandez, P. P.; Rajendran, P.; Hui, K. M.; Sethi, G. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. Cancer Letters 2010, 292 (2), 197-207.
    • (2010) Cancer Letters , vol.292 , Issue.2 , pp. 197-207
    • Li, F.1    Fernandez, P.P.2    Rajendran, P.3    Hui, K.M.4    Sethi, G.5
  • 187
    • 78651461704 scopus 로고    scopus 로고
    • Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells
    • Lepage, C.; Léger, D.Y.; Bertrand, J.; Martin, F.; Beneytout, J.L.; Liagre B. Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells. Cancer Letters 2011, 301 (2), 193-202
    • (2011) Cancer Letters , vol.301 , Issue.2 , pp. 193-202
    • Lepage, C.1    Léger, D.Y.2    Bertrand, J.3    Martin, F.4    Beneytout, J.L.5    Liagre, B.6
  • 189
    • 79957864125 scopus 로고    scopus 로고
    • Chemoprevention of azoxymethane/ dextran sodium sulfate-induced mouse colon carcinogenesis by freeze-dried yam sanyaku and its constituent diosgenin
    • Miyoshi, N.; Nagasawa, T.; Mabuchi, R.; Yasui, Y.; Wakabayashi, K.; Tanaka, T.; Ohshima, H. Chemoprevention of azoxymethane/ dextran sodium sulfate-induced mouse colon carcinogenesis by freeze-dried yam sanyaku and its constituent diosgenin. Cancer Prev. Res. (Phila). 2011, 4 (6), 924-934.
    • (2011) Cancer Prev. Res. (Phila) , vol.4 , Issue.6 , pp. 924-934
    • Miyoshi, N.1    Nagasawa, T.2    Mabuchi, R.3    Yasui, Y.4    Wakabayashi, K.5    Tanaka, T.6    Ohshima, H.7
  • 190
    • 0036832620 scopus 로고    scopus 로고
    • Resveratrol inhibits proliferationand induces apoptosis in human pancreatic cancer cells
    • Ding, X. Z.; Adrian, T. E. Resveratrol inhibits proliferationand induces apoptosis in human pancreatic cancer cells. Pancreas 2002, 25, e71-e76.
    • (2002) Pancreas , vol.25
    • Ding, X.Z.1    Adrian, T.E.2
  • 192
    • 0037347040 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis in human esophageal carcinoma cells
    • Zhou, H. B.; Yan, Y.; Sun, Y. N.; Zhu, J. R. Resveratrol induces apoptosis in human esophageal carcinoma cells. World J. Gastroenterol. 2003, 9, 408-411.
    • (2003) World J. Gastroenterol , vol.9 , pp. 408-411
    • Zhou, H.B.1    Yan, Y.2    Sun, Y.N.3    Zhu, J.R.4
  • 193
    • 0033602719 scopus 로고    scopus 로고
    • Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines
    • Hsieh, T. C.; Wu, J. M. Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines. Exp. Cell Res. 1999, 249, 109-115.
    • (1999) Exp. Cell Res , vol.249 , pp. 109-115
    • Hsieh, T.C.1    Wu, J.M.2
  • 195
    • 3042606371 scopus 로고    scopus 로고
    • Involvement of p21WAF1/ CIP1, pRB, Bax and NF-kappaB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells
    • Kim, Y. A.; Lee, W. H.; Choi, T. H.; Rhee, S. H.; Park, K. Y.; Choi, Y. H. Involvement of p21WAF1/ CIP1, pRB, Bax and NF-kappaB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells. Int. J. Oncol. 2003, 23, 1143-1149.
    • (2003) Int. J. Oncol , vol.23 , pp. 1143-1149
    • Kim, Y.A.1    Lee, W.H.2    Choi, T.H.3    Rhee, S.H.4    Park, K.Y.5    Choi, Y.H.6
  • 196
    • 0035954245 scopus 로고    scopus 로고
    • Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action
    • Kozuki, Y.; Miura, Y.; Yagasaki, K. Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action. Cancer Lett. 2001, 167, 151-156.
    • (2001) Cancer Lett , vol.167 , pp. 151-156
    • Kozuki, Y.1    Miura, Y.2    Yagasaki, K.3
  • 197
    • 0036962164 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism
    • Shih, A.; Davis, F. B.; Lin, H. Y.; Davis, P. J. Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism. J. Clin. Endocrinol. Metab. 2002, 87, 1223-1232.
    • (2002) J. Clin. Endocrinol. Metab , vol.87 , pp. 1223-1232
    • Shih, A.1    Davis, F.B.2    Lin, H.Y.3    Davis, P.J.4
  • 198
    • 0035881270 scopus 로고    scopus 로고
    • Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adeno-carcinoma (Ishikawa) cells
    • Bhat, K. P.; Pezzuto, J. M. Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adeno-carcinoma (Ishikawa) cells. Cancer Res. 2001, 61, 6137-6144.
    • (2001) Cancer Res , vol.61 , pp. 6137-6144
    • Bhat, K.P.1    Pezzuto, J.M.2
  • 199
    • 0033036639 scopus 로고    scopus 로고
    • Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation
    • ElAttar, T. M.; Virji, A. S. Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation. Anticancer Drugs 1999, 10, 187-193.
    • (1999) Anticancer Drugs , vol.10 , pp. 187-193
    • Elattar, T.M.1    Virji, A.S.2
  • 201
    • 0037378391 scopus 로고    scopus 로고
    • Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells
    • Liang, Y. C.; Tsai, S. H.; Chen, L.; Lin-Shiau, S. Y.; Lin, J. K. Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells. Biochem. Pharmacol. 2003, 65, 1053-1060.
    • (2003) Biochem. Pharmacol , vol.65 , pp. 1053-1060
    • Liang, Y.C.1    Tsai, S.H.2    Chen, L.3    Lin-Shiau, S.Y.4    Lin, J.K.5
  • 203
    • 0034917689 scopus 로고    scopus 로고
    • Resveratrol inhibits the expression of cyclooxygenase-2 in mammary epithelial cells
    • Subbaramaiah, K.; Dannenberg, A. J. Resveratrol inhibits the expression of cyclooxygenase-2 in mammary epithelial cells. Adv. Exp. Med. Biol. 2001, 492, 147-157.
    • (2001) Adv. Exp. Med. Biol , vol.492 , pp. 147-157
    • Subbaramaiah, K.1    Dannenberg, A.J.2
  • 204
    • 0003133991 scopus 로고    scopus 로고
    • Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity
    • MacCarrone, M.; Lorenzon, T.; Guerrieri, P.; Agro, A. F. Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity. Eur. J. Biochem. 1999, 265, 27-34.
    • (1999) Eur. J. Biochem , vol.265 , pp. 27-34
    • Maccarrone, M.1    Lorenzon, T.2    Guerrieri, P.3    Agro, A.F.4
  • 205
    • 0141816807 scopus 로고    scopus 로고
    • Anti-inflammatory effect of the oligomeric stilbene alpha-Viniferin and its mode of the action through inhibition of cyclooxygenase-2 and inducible nitric oxide synthase
    • Chung, E. Y.; Kim, B. H.; Lee, M. K.; Yun, Y. P.; Lee, S. H.; Min, K. R.; Kim, Y. Anti-inflammatory effect of the oligomeric stilbene alpha-Viniferin and its mode of the action through inhibition of cyclooxygenase-2 and inducible nitric oxide synthase. Planta Med. 2003, 69, 710-714.
    • (2003) Planta Med , vol.69 , pp. 710-714
    • Chung, E.Y.1    Kim, B.H.2    Lee, M.K.3    Yun, Y.P.4    Lee, S.H.5    Min, K.R.6    Kim, Y.7
  • 206
    • 0036784966 scopus 로고    scopus 로고
    • Comparative antiproliferative and apoptotic effects of resveratrol, epsilon-viniferin and vine-shots derived polyphenols (vineatrols) on chronic B lymphocytic leukemia cells and normal human lymphocytes
    • Billard, C.; Izard, J. C.; Roman, V.; Kern, C.; Mathiot, C.; Mentz, F.; Kolb, J. P. Comparative antiproliferative and apoptotic effects of resveratrol, epsilon-viniferin and vine-shots derived polyphenols (vineatrols) on chronic B lymphocytic leukemia cells and normal human lymphocytes. Leuk. Lymphoma 2002, 43, 1991-2002.
    • (2002) Leuk. Lymphoma , vol.43 , pp. 1991-2002
    • Billard, C.1    Izard, J.C.2    Roman, V.3    Kern, C.4    Mathiot, C.5    Mentz, F.6    Kolb, J.P.7
  • 207
    • 0035801440 scopus 로고    scopus 로고
    • Anti-inflammatory tetramers of resveratrol from the roots of Vitis amurensis and the conformations of the seven-membered ring in some oligostilbenes
    • Huang, K. S.; Lin, M.; Cheng, G. F. Anti-inflammatory tetramers of resveratrol from the roots of Vitis amurensis and the conformations of the seven-membered ring in some oligostilbenes. Phytochemistry 2001, 58, 357-362.
    • (2001) Phytochemistry , vol.58 , pp. 357-362
    • Huang, K.S.1    Lin, M.2    Cheng, G.F.3
  • 208
    • 0033129760 scopus 로고    scopus 로고
    • Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice
    • Zhong, M.; Cheng, G. F.; Wang, W. J.; Guo, Y.; Zhu, X. Y.; Zhang, J. T. Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice. Phytomedicine 1999, 6, 79-84.
    • (1999) Phytomedicine , vol.6 , pp. 79-84
    • Zhong, M.1    Cheng, G.F.2    Wang, W.J.3    Guo, Y.4    Zhu, X.Y.5    Zhang, J.T.6
  • 209
    • 0033915152 scopus 로고    scopus 로고
    • Resveratrol inhibits the growth of Helicobacter pylori invitro
    • Mahady, G. B.; Pendland, S. L. Resveratrol inhibits the growth of Helicobacter pylori invitro. Am. J. Gastroenterol. 2000, 95, 1849.
    • (2000) Am. J. Gastroenterol , vol.95 , pp. 1849
    • Mahady, G.B.1    Pendland, S.L.2
  • 210
    • 0034900080 scopus 로고    scopus 로고
    • Downregulation of the cyclin D1/Cdk4 complex occurs during resveratrol-induced cell cycle arrest in colon cancer cell lines
    • Wolter, F.; Akoglu, B.; Clausnitzer, A.; Stein, J. Downregulation of the cyclin D1/Cdk4 complex occurs during resveratrol-induced cell cycle arrest in colon cancer cell lines. J. Nutr. 2001, 131, 2197-2203.
    • (2001) J. Nutr , vol.131 , pp. 2197-2203
    • Wolter, F.1    Akoglu, B.2    Clausnitzer, A.3    Stein, J.4
  • 211
    • 0033860505 scopus 로고    scopus 로고
    • Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression
    • Tessitore, L.; Davit, A.; Sarotto, I.; Caderni, G. Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression. Carcinogenesis 2000, 21, 1619-1622.
    • (2000) Carcinogenesis , vol.21 , pp. 1619-1622
    • Tessitore, L.1    Davit, A.2    Sarotto, I.3    Caderni, G.4
  • 212
    • 33745278897 scopus 로고    scopus 로고
    • Modulatory influence of dietary resveratrol during different phases of 1,2-dimethylhydrazine inducedmucosal lipidperoxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis
    • Sengottuvelan, M.; Senthilkumar, R.; Nalini, N. Modulatory influence of dietary resveratrol during different phases of 1,2-dimethylhydrazine inducedmucosal lipidperoxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis. Biochim. Biophys. Acta. 2006, 1760, 1175-1183.
    • (2006) Biochim. Biophys. Acta , vol.1760 , pp. 1175-1183
    • Sengottuvelan, M.1    Senthilkumar, R.2    Nalini, N.3
  • 213
    • 77649184736 scopus 로고    scopus 로고
    • Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines
    • Yan, S. L.; Huang, C. Y.; Wu, S. T.; Yin, M. C. Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines. Toxicol. In vitro 2010, 24 (3), 842-848.
    • (2010) Toxicol. In Vitro , vol.24 , Issue.3 , pp. 842-848
    • Yan, S.L.1    Huang, C.Y.2    Wu, S.T.3    Yin, M.C.4
  • 214
    • 67449138570 scopus 로고    scopus 로고
    • Oleanolic acid isolated from Oldenlandia diffusa exhibits a unique growth inhibitory effect against ras-transformed fibroblasts
    • Wu, P. K.; Chi Shing, Tai, W.; Liang, Z. T.; Zhao, Z. Z.; Hsiao, W. L. Oleanolic acid isolated from Oldenlandia diffusa exhibits a unique growth inhibitory effect against ras-transformed fibroblasts. Life Sci. 2009, 85 (3-4), 113-121.
    • (2009) Life Sci , vol.85 , Issue.3-4 , pp. 113-121
    • Wu, P.K.1    Shing, C.2    Tai, W.3    Liang, Z.T.4    Zhao, Z.Z.5    Hsiao, W.L.6
  • 216
    • 61449166861 scopus 로고    scopus 로고
    • On the interference of boswellic acids with 5-lipoxygenase: Mechanistic studies In vitro and pharmacological relevance
    • Siemoneit, U.; Pergola, C.; Jazzar, B.; Northoff, H.; Skarke, C.; Jauch, J.; Werz, O. On the interference of boswellic acids with 5-lipoxygenase: mechanistic studies In vitro and pharmacological relevance. Eur. J. Pharmacol. 2009, 606 (1-3), 246-254.
    • (2009) Eur. J. Pharmacol , vol.606 , Issue.1-3 , pp. 246-254
    • Siemoneit, U.1    Pergola, C.2    Jazzar, B.3    Northoff, H.4    Skarke, C.5    Jauch, J.6    Werz, O.7
  • 217
    • 0029035973 scopus 로고
    • Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid
    • Safayhi, H.; Sailer, E. R.; Ammon, H. P. Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid. Mol. Pharmacol. 1995, 47 (6), 1212-1216.
    • (1995) Mol. Pharmacol , vol.47 , Issue.6 , pp. 1212-1216
    • Safayhi, H.1    Sailer, E.R.2    Ammon, H.P.3
  • 218
    • 0031672111 scopus 로고    scopus 로고
    • Characterization of an acetyl-11-keto-beta-boswellic acid and arachidonate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling
    • Sailer, E. R.; Schweizer, S.; Boden, S. E.; Ammon, H. P.; Safayhi, H. Characterization of an acetyl-11-keto-beta-boswellic acid and arachidonate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling. Eur. J. Biochem. 1998, 256 (2), 364-368.
    • (1998) Eur. J. Biochem , vol.256 , Issue.2 , pp. 364-368
    • Sailer, E.R.1    Schweizer, S.2    Boden, S.E.3    Ammon, H.P.4    Safayhi, H.5
  • 220
    • 68549111000 scopus 로고    scopus 로고
    • LY294002 enhances boswellic acid-induced apoptosis in colon cancer cells
    • Liu, J. J.; Duan, R. D. LY294002 enhances boswellic acid-induced apoptosis in colon cancer cells. Anticancer Res. 2009, 29, 2987-2991.
    • (2009) Anticancer Res , vol.29 , pp. 2987-2991
    • Liu, J.J.1    Duan, R.D.2
  • 221
    • 0031802980 scopus 로고    scopus 로고
    • Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture
    • Shao, Y.; Ho, C. T.; Chin, C. K.; Badmaev, V.; Ma, W.; Huang, M. T. Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture. Planta Med. 1998, 64, 328-331.
    • (1998) Planta Med , vol.64 , pp. 328-331
    • Shao, Y.1    Ho, C.T.2    Chin, C.K.3    Badmaev, V.4    Ma, W.5    Huang, M.T.6
  • 222
    • 80055116342 scopus 로고    scopus 로고
    • Boswellic acid suppresses growth and metastasis of human pancreatic tumors in an orthotopic nude mouse model through modulation of multiple targets
    • Park, B.; Prasad, S.; Yadav, V.; Sung, B.; Aggarwal, B. B. Boswellic acid suppresses growth and metastasis of human pancreatic tumors in an orthotopic nude mouse model through modulation of multiple targets. PLoS One. 2011, 6 (10), e26943.
    • (2011) PLoS One , vol.6 , Issue.10
    • Park, B.1    Prasad, S.2    Yadav, V.3    Sung, B.4    Aggarwal, B.B.5
  • 223
    • 0036949876 scopus 로고    scopus 로고
    • Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells
    • Liu, J. J.; Nilsson, A.; Oredsson, S.; Badmaev, V.; Zhao, W. Z.; Duan, R. D. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002, 23 (12), 2087-2093.
    • (2002) Carcinogenesis , vol.23 , Issue.12 , pp. 2087-2093
    • Liu, J.J.1    Nilsson, A.2    Oredsson, S.3    Badmaev, V.4    Zhao, W.Z.5    Duan, R.D.6
  • 224
    • 84857505779 scopus 로고    scopus 로고
    • Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers
    • Yadav, V. R.; Prasad, S.; Sung, B.; Gelovani, J. G.; Guha, S.; Krishnan, S.; Aggarwal, B. B. Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers. Int. J. Cancer. 2012, 130 (9), 2176-2184.
    • (2012) Int. J. Cancer , vol.130 , Issue.9 , pp. 2176-2184
    • Yadav, V.R.1    Prasad, S.2    Sung, B.3    Gelovani, J.G.4    Guha, S.5    Krishnan, S.6    Aggarwal, B.B.7
  • 225
    • 0034492409 scopus 로고    scopus 로고
    • Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid
    • Huang, M. T.; Badmaev, V.; Ding, Y.; Liu, Y.; Xie, J. G.; Ho, C. T. Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid. Biofactors 2000, 13 (1-4), 225-230.
    • (2000) Biofactors , vol.13 , Issue.1-4 , pp. 225-230
    • Huang, M.T.1    Badmaev, V.2    Ding, Y.3    Liu, Y.4    Xie, J.G.5    Ho, C.T.6
  • 227
    • 10844262511 scopus 로고    scopus 로고
    • Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-a induction in monocytes by direct interaction with IkB kinases
    • Syrovets, T.; Buchele, B.; Krauss, C; Laumonnier, Y.; Simmet, T. Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-a induction in monocytes by direct interaction with IkB kinases. J. Immunol. 2005, 174 (1), 498-506.
    • (2005) J. Immunol , vol.174 , Issue.1 , pp. 498-506
    • Syrovets, T.1    Buchele, B.2    Krauss, C.3    Laumonnier, Y.4    Simmet, T.5
  • 228
    • 53149141375 scopus 로고    scopus 로고
    • Protective effect of lupeol and lupeol linoleate in hypercholesterolemia associated renal damage
    • Sudhakar, V.; Ashok Kumar, S.; Varalakshmi, P.; Sujatha, V. Protective effect of lupeol and lupeol linoleate in hypercholesterolemia associated renal damage. Mol. Cell Biochem. 2008, 317, 11-20.
    • (2008) Mol. Cell Biochem , vol.317 , pp. 11-20
    • Sudhakar, V.1    Ashok Kumar, S.2    Varalakshmi, P.3    Sujatha, V.4
  • 229
    • 34547936387 scopus 로고    scopus 로고
    • Anti-inflammatory and analgesic activities of the ethanolic extracts from Zanthoxylum riedelianum (Rutaceae) leaves and stem bark
    • Lima, L. M.; Perazzo, F. F.; Tavares Carvalho, J. C; Bastos, J. K. Anti-inflammatory and analgesic activities of the ethanolic extracts from Zanthoxylum riedelianum (Rutaceae) leaves and stem bark. J. Pharm. Pharmacol. 2007, 59, 1151-1158.
    • (2007) J. Pharm. Pharmacol , vol.59 , pp. 1151-1158
    • Lima, L.M.1    Perazzo, F.F.2    Tavares Carvalho, J.C.3    Bastos, J.K.4
  • 231
    • 0342526819 scopus 로고    scopus 로고
    • Antiinflammatory effect of Pimenta racemosa var. ozua and isolation of the triterpene lupeol
    • Fernández, A.; Alvarez, A.; García, M. D.; Sáenz, M. T. Antiinflammatory effect of Pimenta racemosa var. ozua and isolation of the triterpene lupeol. Farmaco. 2001, 56, 335-338.
    • (2001) Farmaco , vol.56 , pp. 335-338
    • Fernández, A.1    Alvarez, A.2    García, M.D.3    Sáenz, M.T.4
  • 232
    • 0028717745 scopus 로고
    • Aloe vera, hydrocortisone and sterol influence on wound tensile strength and anti-inflammation
    • Davis, R. H.; DiDonato, J. J.; Johnson, R. W.; Stewart, C. B. Aloe vera, hydrocortisone and sterol influence on wound tensile strength and anti-inflammation. J. Am. Podiatr. Med. Assoc. 1994, 84 (12), 614-621.
    • (1994) J. Am. Podiatr. Med. Assoc , vol.84 , Issue.12 , pp. 614-621
    • Davis, R.H.1    Didonato, J.J.2    Johnson, R.W.3    Stewart, C.B.4
  • 234
    • 1842588753 scopus 로고    scopus 로고
    • Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrine
    • Gutierrez-Lugo, M. T.; Deschamps, J. D.; Holman, T. R.; Suarez, E.; Timmermann, B. N. Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrine. Planta Med. 2004, 70, 263-265.
    • (2004) Planta Med , vol.70 , pp. 263-265
    • Gutierrez-Lugo, M.T.1    Deschamps, J.D.2    Holman, T.R.3    Suarez, E.4    Timmermann, B.N.5
  • 236
    • 0032907734 scopus 로고    scopus 로고
    • Anticomplement activity of triterpenes from Crataeva nurvala stem bark in adjuvant arthritis in rats
    • Geetha, T.; Varalakshmi, P. Anticomplement activity of triterpenes from Crataeva nurvala stem bark in adjuvant arthritis in rats. Gen. Pharmacol. 1999, 32, 495-497.
    • (1999) Gen. Pharmacol , vol.32 , pp. 495-497
    • Geetha, T.1    Varalakshmi, P.2
  • 238
    • 20444466931 scopus 로고    scopus 로고
    • Expression of estrogen receptor alpha gene in breast cancer cells treated with transcription factor decoy is modulated by bangladeshi natural plant extracts
    • Lambertini, E.; Lampronti, I.; Penolazzi, L.; Khan, M. T. H.; Ather, A.; Giorgi, G.; Gambari, R.; Piva, R. Expression of estrogen receptor alpha gene in breast cancer cells treated with transcription factor decoy is modulated by bangladeshi natural plant extracts. Oncology Res. 2005, 14, 69-79.
    • (2005) Oncology Res , vol.14 , pp. 69-79
    • Lambertini, E.1    Lampronti, I.2    Penolazzi, L.3    Khan, M.T.H.4    Ather, A.5    Giorgi, G.6    Gambari, R.7    Piva, R.8
  • 239
    • 28244433538 scopus 로고    scopus 로고
    • Remodeling of actin cytoskeleton in lupeol-induced B16 2F2 cell differentiation
    • Hata, K.; Hori, K.; Murata, J.; Takahashi, S. Remodeling of actin cytoskeleton in lupeol-induced B16 2F2 cell differentiation. J Biochem. 2005, 138 (4), 467-472.
    • (2005) J Biochem , vol.138 , Issue.4 , pp. 467-472
    • Hata, K.1    Hori, K.2    Murata, J.3    Takahashi, S.4
  • 240
    • 27744500461 scopus 로고    scopus 로고
    • Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway
    • Saleem, M.; Kaur, S.; Kweon, M. H.; Adhami, V. M.; Afaq, F.; Mukhtar, H. Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway. Carcinogenesis 2005, 26 (11), 1956-1964.
    • (2005) Carcinogenesis , vol.26 , Issue.11 , pp. 1956-1964
    • Saleem, M.1    Kaur, S.2    Kweon, M.H.3    Adhami, V.M.4    Afaq, F.5    Mukhtar, H.6
  • 241
    • 33747203295 scopus 로고    scopus 로고
    • Glycosidation of lupane-type triterpenoids as potent In vitro cytotoxic agents
    • Gauthier, C; Legault, J.; Lebrun, M.; Dufour, P.; Pichette, A. Glycosidation of lupane-type triterpenoids as potent In vitro cytotoxic agents. Bioorg. Med. Chem. 2006, 14 (19), 6713-6725.
    • (2006) Bioorg. Med. Chem , vol.14 , Issue.19 , pp. 6713-6725
    • Gauthier, C.1    Legault, J.2    Lebrun, M.3    Dufour, P.4    Pichette, A.5
  • 242
    • 84857288575 scopus 로고
    • Major tropical spices cardamom (Elettaria cardamomum)
    • Allured Publishers, Wheaton
    • Lawrence, B. M. Major tropical spices cardamom (Elettaria cardamomum). In: Essential oils. Allured Publishers, Wheaton, 1979, p104.
    • (1979) Essential Oils
    • Lawrence, B.M.1
  • 243
    • 0028330268 scopus 로고
    • Modulatory effects of essential oils from spices on the formation of DNA adduct by aflatoxin B1 In vitro
    • Hashim, S.; Aboobaker, V. S.; Madhubala, R.; Bhattacharya, R. K.; Rao, A. R. Modulatory effects of essential oils from spices on the formation of DNA adduct by aflatoxin B1 In vitro. Nutr. Cancer 1994, 21 (2), 169-175.
    • (1994) Nutr. Cancer , vol.21 , Issue.2 , pp. 169-175
    • Hashim, S.1    Aboobaker, V.S.2    Madhubala, R.3    Bhattacharya, R.K.4    Rao, A.R.5
  • 244
    • 0034047536 scopus 로고    scopus 로고
    • Antiinflammatory and antinociceptive effect of 1,8-Cineole a terpenoid oxide present in many plant essential oils
    • Santos, F. A.; Rao, V. S. Antiinflammatory and antinociceptive effect of 1,8-Cineole a terpenoid oxide present in many plant essential oils. Phytother. Res. 2000, 14 (4), 240-244.
    • (2000) Phytother. Res , vol.14 , Issue.4 , pp. 240-244
    • Santos, F.A.1    Rao, V.S.2
  • 245
    • 0032541520 scopus 로고    scopus 로고
    • Antiinflammtory effects of euclyptol (1,8-cineole) in bronchial asthma: Inhibition of arachidonic acid metabolism in human blood monocytes ex vivo
    • Juergens, U. R.; Stober, M.; Schmidt-Schilling, L.; Kleuver, T.; Vetter, H. Antiinflammtory effects of euclyptol (1,8-cineole) in bronchial asthma: Inhibition of arachidonic acid metabolism in human blood monocytes ex vivo. Eur. J. Med. Res. 1998, 3 (9), 407-412.
    • (1998) Eur. J. Med. Res , vol.3 , Issue.9 , pp. 407-412
    • Juergens, U.R.1    Stober, M.2    Schmidt-Schilling, L.3    Kleuver, T.4    Vetter, H.5
  • 246
    • 5144232048 scopus 로고    scopus 로고
    • Inhibitory activity of 1,8-Cineole (eucalyptol) on cytokine production in cultured human lymphocytes and monocytes
    • Juergens, U. R.; Engelen, T.; Racke, K.; Stober, M.; Gillissen, A.; Vetter, H. Inhibitory activity of 1,8-Cineole (eucalyptol) on cytokine production in cultured human lymphocytes and monocytes. Pulm. Pharmacol. Ther. 2004, 17 (5), 281-287.
    • (2004) Pulm. Pharmacol. Ther , vol.17 , Issue.5 , pp. 281-287
    • Juergens, U.R.1    Engelen, T.2    Racke, K.3    Stober, M.4    Gillissen, A.5    Vetter, H.6
  • 247
    • 24944458215 scopus 로고    scopus 로고
    • Dietary cardamom inhibits the formation of azoxymethane induced aberrant crypt foci and reduces COX2 and iNOS expression in colon
    • Sengupta, A.; Ghosh, S.; Bhattacharjee, S. Dietary cardamom inhibits the formation of azoxymethane induced aberrant crypt foci and reduces COX2 and iNOS expression in colon. Asian Pac. J. Cancer Prev. 2005, 6, 118-122.
    • (2005) Asian Pac. J. Cancer Prev , vol.6 , pp. 118-122
    • Sengupta, A.1    Ghosh, S.2    Bhattacharjee, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.