Constitutive activation of IκB kinase α and NF-κB in prostate cancer cells is inhibited by ibuprofen

Oncogene

Volumn 18, Issue 51, 1999, Pages 7389-7394

  Palayoor, S T ^b   Youmell, M Y ^a   Calderwood, S K ^a   Coleman, C N ^b   Price, B D ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Androgen; Ibuprofen; IKK ; NF B; Prostate; Tumor

Indexed keywords

IBUPROFEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; CHUK PROTEIN, HUMAN; I KAPPA B KINASE; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN SERINE THREONINE KINASE;

ARTICLE; DNA BINDING; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INHIBITION; PRIORITY JOURNAL; TUMOR CELL LINE; CELL CULTURE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; PROSTATE TUMOR;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; I-KAPPA B KINASE; IBUPROFEN; MALE; NF-KAPPA B; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; TUMOR CELLS, CULTURED;

EID: 0033517999     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203160     Document Type: Article

References (31)

1. Apakama I, Robinson M, Walter N, Charlton R, Royds J, Fuller C, Neal D and Hamdy F. (1996). Br. J. Cancer, 8, 1258-1262.
2. Baeuerle PA and Baltimore D. (1996). Cell, 87, 13-20.
3. Basu S, Rosenzweig KE, Youmell MY and Price BD. (1998). Biochem. Biophys. Res. Comm., 247, 79-83.
4. Beg AA and Baltimore D. (1996). Science, 274, 782-784.
5. Cohen L, Henzel WJ and Baeuerle PA. (1998). Nature, 395, 292-296.
6. de Moissac D, Mustapha S, Greenberg AH and Kirshenbaum LA. (1998). J. Biol. Chem., 273, 23946-23951.
7. DeWitt D and Smith WL. (1995). Cell, 83, 345-348.
8. Kopp E and Ghosh S. (1994). Science, 265, 956-959.
9. Krappmann D, Emmerich F, Kordes U, Scharschmidt E, Dorken B and Scheidercit C. (1999). Oncogene, 18, 943 953.
10. Laska EM, Sunshine A, Marrero I, Olson N, Siegel C and McCormick N. (1986). Clin. Pharm. Ther., 40, 1-7.
11. Latchman DS. (1999). J. Cell. Physiol., 179, 126-133.
12. Lee FS, Peters RT, Dang LC and Maniatis T. (1998). Proc. Natl. Acad. Sci. USA, 95, 9319-9324.
13. Ling L, Cao Z and Goeddel DV. (1998). Proc. Natl. Acad. Sci. USA, 95, 3792-3797.
14. Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li JW, Young DB, Barbossa M, Mann M, Manning A and Rao A. (1997). Science, 278, 860-866.
15. Miyamato S and Verma IM. (1995). Adv. Cancer Res., 66, 255-292.
16. Nakajima Y, DelliPizzi AM, Mallouh C and Ferreri R. (1996). Prostate, 29, 296-302.
17. Nakshatri H, Bhat-Nakshatri P, Martin DA, Goulet RJ and Sledge GW. (1997). Mol. Cell Biol., 17, 3629-3639.
18. Palayoor ST, Bump EA, Calderwood SK, Bartol S and Coleman CN. (1998). Clin. Cancer Res., 4, 763-771.
19. Palvimo JJ, Reinikainen P, Ikonen T, Kallio PJ, Moilanen A and Janne OA. (1996). J. Biol. Chem., 271, 24151-24156.
20. Perez P, Lira SA and Bravo R. (1995). Mol. Cell Biol., 15, 3523-3530.
21. Soncin F and Calderwood SK. (1996). Biochem. Biophys. Res. Comm., 229, 479-484.
22. Sun S-C, Ganchi PA, Ballard DW and Greene WC. (1993). Science, 259, 1912-1915.
23. Supakar PC, Jung MH, Song CS, Chatterjee B and Roy A. (1995). J. Biol. Chem., 270, 837-842.
24. Teicher BA, Bump EA, Palayoor S, Northey D and Coleman CN. (1996). Rad. Oncol. Invest., 4, 221-230.
25. Tilley WD, Wilson CM, Marcelli M and McPhaul MJ. (1990). Cancer Res., 50, 5382-5386.
26. Traenckner EB, Pahl HL, Henkel T, Schmidt KN, Wilk S and Baeuerle PA. (1995). EMBO J., 14, 2876-2883.
27. Wang C-Y, Mayo MW and Baldwin AS. (1996). Science, 274, 784-787.
28. Wang C-Y, Mayo MW, Korneluk RG, Goeddel DV and Baldwin AS. (1998). Science, 281, 1680-1683.
29. Wu MX, Ao Z, Prasad KVS, Wu R and Schlossman SF. (1998). Science, 281, 998-1001.
30. Yin MJ, Yamamoto Y and Gaynor RB. (1998). Nature, 396, 77-80.
31. Zandi E, Chen Y and Karin M. (1998). Science, 281, 1360-1363.