Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers

International Journal of Cancer

Volumn 130, Issue 9, 2012, Pages 2176-2184

  Yadav, Vivek R ^a   Prasad, Sahdeo ^a   Sung, Bokyung ^a   Gelovani, Juri G ^a   Guha, Sushovan ^a   Krishnan, Sunil ^a   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

AKBA; colorectal cancer; growth; metastasis; NF kB

Indexed keywords

ACETYL 11 OXO BETA BOSWELLIC ACID; ANTINEOPLASTIC AGENT; BOSWELLIC ACID; CD31 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CYCLIN D1; CYCLOOXYGENASE 2; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INTERCELLULAR ADHESION MOLECULE 1; KI 67 ANTIGEN; PROTEIN BCL 2; PROTEIN BCL XL; SURVIVIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; ASCITES; BODY WEIGHT; CANCER INHIBITION; CANCER INVASION; CANCER MODEL; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; DISTANT METASTASIS; DOSE RESPONSE; DOWN REGULATION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG TISSUE LEVEL; HUMAN; HUMAN CELL; INFLAMMATION; LIVER METASTASIS; LUNG METASTASIS; MALE; METASTASIS INHIBITION; MICROVASCULATURE; MICROVESSEL DENSITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; SPLEEN METASTASIS; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; BOSWELLIA; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; INFLAMMATION; MALE; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; TRITERPENES; TUMOR MARKERS, BIOLOGICAL; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84857505779     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26251     Document Type: Article

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