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Volumn 32, Issue 10, 2011, Pages 1441-1449

Deletion of cyclooxygenase 2 in mouse mammary epithelial cells delays breast cancer onset through augmentation of type 1 immune responses in tumors

Author keywords

[No Author keywords available]

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; CD45 ANTIGEN; CD86 ANTIGEN; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; CYTOKINE; GENOMIC DNA; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MEDROXYPROGESTERONE ACETATE; MESSENGER RNA; PROSTAGLANDIN E2; ROFECOXIB; TUMOR NECROSIS FACTOR ALPHA;

EID: 80053137426     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr134     Document Type: Article
Times cited : (35)

References (51)
  • 1
    • 64049109107 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung
    • Harris,R.E. (2009) Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung. Inflammopharmacology, 17, 55-67.
    • (2009) Inflammopharmacology , vol.17 , pp. 55-67
    • Harris, R.E.1
  • 2
    • 40349113534 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer
    • Howe,L.R. (2007) Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer. Breast Cancer Res., 9, 210.
    • (2007) Breast Cancer Res , vol.9 , pp. 210
    • Howe, L.R.1
  • 3
    • 3042748128 scopus 로고    scopus 로고
    • The role of COX-2 inhibition in breast cancer treatment and prevention
    • Arun,B. et al. (2004) The role of COX-2 inhibition in breast cancer treatment and prevention. Semin. Oncol., 31, 22-9.
    • (2004) Semin. Oncol. , vol.31 , pp. 22-29
    • Arun, B.1
  • 4
    • 0036792206 scopus 로고    scopus 로고
    • Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neuinduced breast cancer
    • Howe,L.R. et al. (2002) Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neuinduced breast cancer. Cancer Res., 62, 5405-5407.
    • (2002) Cancer Res , vol.62 , pp. 5405-5407
    • Howe, L.R.1
  • 5
    • 0346732943 scopus 로고    scopus 로고
    • The cyclooxygenase-2 inhibitor, celecoxib, prevents the development of mammary tumors in Her-2/neu mice
    • Lanza-Jacoby,S. et al. (2003) The cyclooxygenase-2 inhibitor, celecoxib, prevents the development of mammary tumors in Her-2/neu mice. Cancer Epidemiol. Biomarkers Prev., 12, 1486-1491.
    • (2003) Cancer Epidemiol. Biomarkers Prev. , vol.12 , pp. 1486-1491
    • Lanza-Jacoby, S.1
  • 6
    • 27544512985 scopus 로고    scopus 로고
    • HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice
    • Howe,L. et al. (2005) HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice. Cancer Res., 65, 10113-10119.
    • (2005) Cancer Res , vol.65 , pp. 10113-10119
    • Howe, L.1
  • 7
    • 0035947709 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice
    • Liu,C.H. et al. (2001) Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J. Biol. Chem., 276, 18563-18569.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18563-18569
    • Liu, C.H.1
  • 8
    • 65349152488 scopus 로고    scopus 로고
    • Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement
    • Cuzick,J. et al. (2009) Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement. Lancet Oncol., 10, 501-507.
    • (2009) Lancet Oncol , vol.10 , pp. 501-507
    • Cuzick, J.1
  • 9
    • 33144481709 scopus 로고    scopus 로고
    • Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors
    • Harris,R. et al. (2006) Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors. BMC Cancer, 6, 27.
    • (2006) BMC Cancer , vol.6 , pp. 27
    • Harris, R.1
  • 10
    • 20144365496 scopus 로고    scopus 로고
    • Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
    • Solomon,S. et al. (2005) Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N. Engl. J. Med., 352, 1071-80.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1071-1080
    • Solomon, S.1
  • 11
    • 33748517838 scopus 로고    scopus 로고
    • Effect of celecoxib on cardiovascular events and blood pressure in two trials for the prevention of colorectal adenomas
    • Solomon,S. et al. (2006) Effect of celecoxib on cardiovascular events and blood pressure in two trials for the prevention of colorectal adenomas. Circulation, 114, 1028-1035.
    • (2006) Circulation , vol.114 , pp. 1028-1035
    • Solomon, S.1
  • 12
    • 77951909982 scopus 로고    scopus 로고
    • Emotion recollected in tranquility: lessons learned from the COX-2 saga
    • Grosser,T. et al. (2010) Emotion recollected in tranquility: lessons learned from the COX-2 saga. Annu. Rev. Med., 61, 17-33.
    • (2010) Annu. Rev. Med. , vol.61 , pp. 17-33
    • Grosser, T.1
  • 13
    • 16444385003 scopus 로고    scopus 로고
    • Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade
    • Wang,D. et al. (2005) Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade. Cancer Res., 65, 1822-1829.
    • (2005) Cancer Res , vol.65 , pp. 1822-1829
    • Wang, D.1
  • 14
    • 0041816104 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
    • Buchanan,F.G. et al. (2003) Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. J. Biol. Chem., 278, 35451-35457.
    • (2003) J. Biol. Chem. , vol.278 , pp. 35451-35457
    • Buchanan, F.G.1
  • 15
    • 0031984810 scopus 로고    scopus 로고
    • Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
    • Sheng,H. et al. (1998) Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res., 58, 362-366.
    • (1998) Cancer Res , vol.58 , pp. 362-366
    • Sheng, H.1
  • 16
    • 28544444039 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis
    • Castellone,M. et al. (2005) Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. Science, 310, 1504-1510.
    • (2005) Science , vol.310 , pp. 1504-1510
    • Castellone, M.1
  • 17
    • 0347717578 scopus 로고    scopus 로고
    • Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression
    • Chang,S. et al. (2004) Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression. Proc. Natl Acad. Sci. USA, 101, 591-596.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 591-596
    • Chang, S.1
  • 18
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce,J.A. et al. (2009) Microenvironmental regulation of metastasis. Nat. Rev. Cancer, 9, 239-252.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1
  • 19
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan,D. et al. (2011) Hallmarks of cancer: the next generation. Cell, 144, 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1
  • 20
    • 76349096670 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaBdependent manner
    • Erez,N. et al. (2010) Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaBdependent manner. Cancer Cell, 17, 135-147.
    • (2010) Cancer Cell , vol.17 , pp. 135-147
    • Erez, N.1
  • 21
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard,J. (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer, 4, 71-78.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 71-78
    • Pollard, J.1
  • 22
    • 62549099627 scopus 로고    scopus 로고
    • Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast
    • Hu,M. et al. (2009) Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast. Proc. Natl Acad. Sci. USA, 106, 3372-3377.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 3372-3377
    • Hu, M.1
  • 23
    • 79955771440 scopus 로고    scopus 로고
    • Macrophages induce COX-2 expression in breast cancer cells: role of IL-1{beta} auto-amplification
    • Hou,Z. et al. (2011) Macrophages induce COX-2 expression in breast cancer cells: role of IL-1{beta} auto-amplification. Carcinogenesis.
    • (2011) Carcinogenesis
    • Hou, Z.1
  • 24
    • 33745215097 scopus 로고    scopus 로고
    • E prostanoid 2 (EP2)/EP4-mediated suppression of antigen-specific human T-cell responses by prostaglandin E2
    • Okano,M. et al. (2006) E prostanoid 2 (EP2)/EP4-mediated suppression of antigen-specific human T-cell responses by prostaglandin E2. Immunology, 118, 343-352.
    • (2006) Immunology , vol.118 , pp. 343-352
    • Okano, M.1
  • 25
    • 77954563614 scopus 로고    scopus 로고
    • Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
    • DeNardo,D.G. et al. (2010) Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity. Cancer Metastasis Rev., 29, 309-316.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 309-316
    • DeNardo, D.G.1
  • 26
    • 77649179672 scopus 로고    scopus 로고
    • Eicosanoids and cancer
    • Wang,D. et al. (2010) Eicosanoids and cancer. Nat. Rev. Cancer, 10, 181-193.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 181-193
    • Wang, D.1
  • 27
    • 78649598159 scopus 로고    scopus 로고
    • Pivotal advance: tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE2 catabolism in myeloid cells
    • Eruslanov,E. et al. (2010) Pivotal advance: tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE2 catabolism in myeloid cells. J. Leukoc. Biol., 88, 839-848.
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 839-848
    • Eruslanov, E.1
  • 28
    • 66149138017 scopus 로고    scopus 로고
    • Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function
    • Wang,D. et al. (2009) Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function. Proc. Natl Acad. Sci. USA, 106, 7548-7552.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 7548-7552
    • Wang, D.1
  • 29
    • 19344363962 scopus 로고    scopus 로고
    • COX-2 inhibitors and genetic background reduce mammary tumorigenesis in cyclooxygenase-2 transgenic mice
    • Narko,K. et al. (2005) COX-2 inhibitors and genetic background reduce mammary tumorigenesis in cyclooxygenase-2 transgenic mice. Prostaglandins Other Lipid Mediat., 76, 86-94.
    • (2005) Prostaglandins Other Lipid Mediat , vol.76 , pp. 86-94
    • Narko, K.1
  • 30
    • 11844277698 scopus 로고    scopus 로고
    • Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
    • Sinha,P. et al. (2005) Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J. Immunol., 174, 636-645.
    • (2005) J. Immunol. , vol.174 , pp. 636-645
    • Sinha, P.1
  • 31
    • 38149042901 scopus 로고    scopus 로고
    • Noninvasive assessment of the role of cyclooxygenases in cardiovascular health: a detailed HPLC/MS/MS method
    • Song,W. et al. (2007) Noninvasive assessment of the role of cyclooxygenases in cardiovascular health: a detailed HPLC/MS/MS method. Methods Enzymol., 433, 51-72.
    • (2007) Methods Enzymol , vol.433 , pp. 51-72
    • Song, W.1
  • 32
    • 11144337833 scopus 로고    scopus 로고
    • Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways
    • Bookout,A. et al. (2003) Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways. Nucl. Recept. Signal, 1, e012.
    • (2003) Nucl. Recept. Signal , vol.1
    • Bookout, A.1
  • 33
    • 11144356465 scopus 로고    scopus 로고
    • A delayed chemically induced tumorigenesis in Brca2 mutant mice
    • Yan,D. et al. (2004) A delayed chemically induced tumorigenesis in Brca2 mutant mice. Oncogene, 23, 1896-1901.
    • (2004) Oncogene , vol.23 , pp. 1896-1901
    • Yan, D.1
  • 34
    • 38449102676 scopus 로고    scopus 로고
    • Macrophage activation and polarization
    • Martinez,F.O. et al. (2008) Macrophage activation and polarization. Front. Biosci., 13, 453-461.
    • (2008) Front. Biosci. , vol.13 , pp. 453-461
    • Martinez, F.O.1
  • 35
    • 65549168745 scopus 로고    scopus 로고
    • Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation
    • Nakayama,M. et al. (2009) Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation. Blood, 113, 3821-3830.
    • (2009) Blood , vol.113 , pp. 3821-3830
    • Nakayama, M.1
  • 36
    • 34247895422 scopus 로고    scopus 로고
    • Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
    • Nakae,S. et al. (2007) Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J. Leukoc. Biol., 81, 1258-1268.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1258-1268
    • Nakae, S.1
  • 37
    • 33745238704 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors
    • Grösch,S. et al. (2006) Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. J. Natl. Cancer Inst., 98, 736-747.
    • (2006) J. Natl. Cancer Inst. , vol.98 , pp. 736-747
    • Grösch, S.1
  • 38
    • 0036142958 scopus 로고    scopus 로고
    • Gene transfer of thromboxane A(2) synthase and prostaglandin I(2) synthase antithetically altered tumor angiogenesis and tumor growth
    • Pradono,P. et al. (2002) Gene transfer of thromboxane A(2) synthase and prostaglandin I(2) synthase antithetically altered tumor angiogenesis and tumor growth. Cancer Res., 62, 63-66.
    • (2002) Cancer Res , vol.62 , pp. 63-66
    • Pradono, P.1
  • 39
    • 22244458283 scopus 로고    scopus 로고
    • Suppression of prostate tumor cell growth by stromal cell prostaglandin D synthase-derived products
    • Kim,J. et al. (2005) Suppression of prostate tumor cell growth by stromal cell prostaglandin D synthase-derived products. Cancer Res., 65, 6189-6198.
    • (2005) Cancer Res , vol.65 , pp. 6189-6198
    • Kim, J.1
  • 40
    • 0021893428 scopus 로고
    • Prostaglandin F2 alpha in benign and malignant breast tumours
    • Vergote,I. et al. (1985) Prostaglandin F2 alpha in benign and malignant breast tumours. Br. J. Cancer, 51, 827-836.
    • (1985) Br. J. Cancer , vol.51 , pp. 827-836
    • Vergote, I.1
  • 41
    • 15244360281 scopus 로고    scopus 로고
    • Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer
    • Sivula,A. et al. (2005) Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer. Breast Cancer Res. Treat., 89, 215-220.
    • (2005) Breast Cancer Res. Treat. , vol.89 , pp. 215-220
    • Sivula, A.1
  • 42
    • 67651160649 scopus 로고    scopus 로고
    • CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • DeNardo,D.G. et al. (2009) CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell, 16, 91-102.
    • (2009) Cancer Cell , vol.16 , pp. 91-102
    • DeNardo, D.G.1
  • 43
    • 33845524204 scopus 로고    scopus 로고
    • Role of tumor-associated macrophages in tumor progression and invasion
    • Mantovani,A. et al. (2006) Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev., 25, 315-322.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 315-322
    • Mantovani, A.1
  • 44
    • 0005339099 scopus 로고    scopus 로고
    • Tumor-associated macrophages in breast cancer
    • Leek,R. et al. (2002) Tumor-associated macrophages in breast cancer. J. Mammary Gland Biol. Neoplasia, 7, 177-189.
    • (2002) J. Mammary Gland Biol. Neoplasia , vol.7 , pp. 177-189
    • Leek, R.1
  • 45
    • 0036038593 scopus 로고    scopus 로고
    • Requirement of macrophages and eosinophils and their cytokines/chemokines for mammary gland development
    • Gouon-Evans,V. et al. (2002) Requirement of macrophages and eosinophils and their cytokines/chemokines for mammary gland development. Breast Cancer Res., 4, 155-164.
    • (2002) Breast Cancer Res , vol.4 , pp. 155-164
    • Gouon-Evans, V.1
  • 46
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani,A. et al. (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol., 23, 549-555.
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1
  • 47
    • 50849118106 scopus 로고    scopus 로고
    • Tumor infiltrating macrophages reduce development of peritoneal colorectal carcinoma metastases
    • van der Bij,G. et al. (2008) Tumor infiltrating macrophages reduce development of peritoneal colorectal carcinoma metastases. Cancer Lett.
    • (2008) Cancer Lett
    • van der Bij, G.1
  • 48
    • 40849118333 scopus 로고    scopus 로고
    • High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer
    • Kim,D. et al. (2008) High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer. Br. J. Cancer, 98, 1118-1124.
    • (2008) Br. J. Cancer , vol.98 , pp. 1118-1124
    • Kim, D.1
  • 49
    • 0029950769 scopus 로고    scopus 로고
    • Macrophages can recognize and kill tumor cells bearing the membrane isoform of macrophage colony-stimulating factor
    • Jadus,M. et al. (1996) Macrophages can recognize and kill tumor cells bearing the membrane isoform of macrophage colony-stimulating factor. Blood, 87, 5232-5241.
    • (1996) Blood , vol.87 , pp. 5232-5241
    • Jadus, M.1
  • 50
    • 67349127266 scopus 로고    scopus 로고
    • Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion
    • Yao,C. et al. (2009) Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion. Nat. Med., 15, 633-640.
    • (2009) Nat. Med. , vol.15 , pp. 633-640
    • Yao, C.1
  • 51
    • 63449127321 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling
    • Boniface,K. et al. (2009) Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J. Exp. Med., 206, 535-548.
    • (2009) J. Exp. Med. , vol.206 , pp. 535-548
    • Boniface, K.1


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