Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway

Carcinogenesis

Volumn 26, Issue 11, 2005, Pages 1956-1964

  Saleem, Mohammad ^a   Kaur, Satwinderjeet ^a   Kweon, Mee Hyang ^a   Adhami, Vaqar Mustafa ^a   Afaq, Farrukh ^a   Mukhtar, Hasan ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUPEOL; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; RAS PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER INHIBITION; CANCER RESISTANCE; CELL GROWTH; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; ONCOGENE RAS; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BLOTTING, WESTERN; ENZYME ACTIVATION; FLOW CYTOMETRY; FRUIT; HUMANS; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; ORNITHINE DECARBOXYLASE; PANCREATIC NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN KINASE C-ALPHA; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RAS PROTEINS; SIGNAL TRANSDUCTION; TRITERPENES; TUMOR CELLS, CULTURED; VEGETABLES;

EID: 27744500461     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi157     Document Type: Article

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