Oral supplementation of piperine leads to altered phase II enzymes and reduced DNA damage and DNA-protein cross links in Benzo(a)pyrene induced experimental lung carcinogenesis

Molecular and Cellular Biochemistry

Volumn 268, Issue 1-2, 2005, Pages 141-147

  Selvendiran, Karuppaiyah ^a   Banu, Syed Mumtaz ^a   Sakthisekaran, Dhanapal ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Comet; DNA damage; Lung cancer; Phase II enzymes; Piperine

Indexed keywords

BENZO[A]PYRENE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; PIPERINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA CROSS LINKING; DNA DAMAGE; DNA PROTEIN COMPLEX; DRUG MECHANISM; ENZYME ACTIVITY; GEL ELECTROPHORESIS; LUNG CANCER; MALE; MOUSE; NONHUMAN; PROTEIN CROSS LINKING; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ADMINISTRATION, ORAL; ALKALOIDS; ANIMALS; BENZO(A)PYRENE; BENZODIOXOLES; DNA; DNA DAMAGE; DOWN-REGULATION; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; LUNG NEOPLASMS; MALE; MICE; NAD(P)H DEHYDROGENASE (QUINONE); PIPERIDINES; POLYUNSATURATED ALKAMIDES;

EID: 14244265798     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11010-005-3702-z     Document Type: Article

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