Dysfunctional synapse in Alzheimer's disease - A focus on NMDA receptors

Neuropharmacology

Volumn 76, Issue PART A, 2014, Pages 16-26

  Mota, Sandra I ^a   Ferreira, Ildete L ^a,b   Rego, A Cristina ^a,b,c  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Alzheimer's disease; Amyloid beta peptide; GluN2A and GluN2B subunits; NMDA receptors; Synaptic dysfunction; Tripartite synapse

Indexed keywords

AMYLOID BETA PROTEIN; BUNGAROTOXIN RECEPTOR; DIZOCILPINE; DONEPEZIL; GALANTAMINE; MEMANTINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NERAMEXANE;

ALZHEIMER DISEASE; AMNESIA; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CELL SURVIVAL; CONFUSION; DRUG EFFECT; DRUG MECHANISM; DRUG TOLERABILITY; ENDOCYTOSIS; ENZYME ACTIVATION; EPISODIC MEMORY; EXCITOTOXICITY; FALLING; HUMAN; HYPERTENSION; MOLECULAR PATHOLOGY; NERVE CELL PLASTICITY; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; RECEPTOR GENE; RECEPTOR UPREGULATION; REVIEW; RISK ASSESSMENT; SOMNOLENCE; SYNAPTIC TRANSMISSION; SYNAPTOSOME; WEIGHT GAIN; WORKING MEMORY;

ALZHEIMER'S DISEASE; AMYLOID-BETA PEPTIDE; GLUN2A AND GLUN2B SUBUNITS; NMDA RECEPTORS; SYNAPTIC DYSFUNCTION; TRIPARTITE SYNAPSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; MODELS, NEUROLOGICAL; MOLECULAR TARGETED THERAPY; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 84886641553     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.08.013     Document Type: Review

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