Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 11, Issue 1, 2007, Pages 97-116

  Jacob, C P ^a   Koutsilieri, E ^a   Bartl, J ^a   Neuen Jacob, E ^b   Arzberger, T ^a   Zander, N ^a   Ravid, R ^c   Roggendorf, W ^a   Riederer, P ^a   Grunblatt E ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c NETHERLANDS BRAIN BANK   (Netherlands)

Author keywords

Alzheimer's disease; Array; Gene expression; Glutamate; Kainate; Quantitative PCR

Indexed keywords

AMPA RECEPTOR; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMATE RECEPTOR; GLUTAMATE TRANSPORTER; KAINIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 33847725506     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2007-11113     Document Type: Article

References (43)

1. G. Amadoro, M.T. Ciotti, M. Costanzi, V. Cestari, P. Calissano and N. Canu, NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation, Proc Natl Acad Sci USA 103(8) (2006), 2892-2897.
2. J. Attems and K.A. Jellinger, Hippocampal sclerosis in Alzheimer disease and other dementias, Neurology 66(5) (2006), 775.
3. M. Benoit, P.M. Koulibaly, O. Migneco, J. Darcourt, D.J. Pringuey and P.H. Robert, Brain perfusion in Alzheimer's disease with and without apathy: a SPECT study with statistical parametric mapping analysis, Psychiatry Res 114(2) (2002), 103-111.
4. B.J. Blanchard, A. Chen, L.M. Rozeboom, K.A. Stafford, P. Weigele and V.M. Ingram, Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule, Proc Natl Acad Sci USA 101(40) (2004), 14326-14332.
5. A. Boldyrev, E. Bulygina and A. Makhro, Glutamate receptors modulate oxidative stress in neuronal cells. A mini-review, Neurotox Res 6(7-8) (2004), 581-587.
6. H. Braak, E. Braak, J. Bohl and W. Lang, Alzheimer's disease: amyloid plaques in the cerebellum, J Neurol Sci 93(2-3) (1989), 277-287.
7. H. Braak, E. Braak, D. Yilmazer, R.A. de Vos, E.N. Jansen and J. Bohl, Pattern of brain destruction in Parkinson's and Alzheimer's diseases, J Neural Transm 103(4) (1996), 455-490.
8. H. Braak and E. Braak, Frequency of stages of Alzheimer-related lesions in different age categories, Neurobiol Aging 18(4) (1997), 351-357.
9. J.M. Claverie, Computational methods for the identification of differential and coordinated gene expression, Hum Mol Genet 8(10) (1999), 1821-1832.
10. F. Esclaire, M. Lesort, C. Blanchard and J. Hugon, Glutamate toxicity enhances tau gene expression in neuronal cultures, J Neurosci Res 49(3) (1997), 309-318.
11. A.M. Floden, S. Li and C.K. Combs, Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors, J Neurosci 25(10) (2005), 2566-2575.
12. E. Grünblatt, S. Hoyer and P. Riederer, Gene expression profile in streptozotocin rat model for sporadic Alzheimer's disease, J Neural Transm 111(3) (2004), 367-386.
13. E. Grünblatt, S. Mandel, J. Jacob-Hirsch, S. Zeligson, N. Amariglo, G. Rechavi, J. Li, R. Ravid, W. Roggendorf, P. Riederer and M.B. Youdim, Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes, J Neural Transm 111(12)(2004) 1543-73.
14. E. Grünblatt, R. Schlößer, P. Fischer, M.O. Fischer, J. Li, E. Koutsilieri, I. Wichart, N. Sterba, D. Rujescu, H.J. Moller, W. Adamcyk, B. Dittrich, F. Muller, K. Oberegger, G. Gatterer, K.J. Jellinger, N. Mostafaie, S. Jungwirth, K. Huber, K.H. Tragl, W. Danielczyk and P. Riederer, Oxidative stress related markers in the "VITA" and the centenarian projects, Neurobiol Aging 26(4) (2005), 429-438.
15. M.R. Hynd, H.L. Scott and P.R. Dodd, Differential expression of N-methyl-D-aspartate receptor NR2 isoforms in Alzheimer's disease, J Neurochem 90(4) (2004), 913-919.
16. E. Koutsilieri, C. Scheller, E. Grünblatt, K. Nara, J. Li and P. Riederer, Free radicals in Parkinson's disease, J Neurol 249(Suppl 2) (2002), II1-5.
17. C.K. Lee, R. Weindruch and T.A. Prolla, Gene-expression profile of the ageing brain in mice, Nat Genet 25(3) (2000), 294-297.
18. M.L. Lee, F.C. Kuo, G.A. Whitmore and J. Sklar, Importance of replication in microarray gene expression studies: statistical methods and evidence from repetitive cDNA hybridizations, Proc Natl Acad Sci USA 97(18) (2000), 9834-9839.
19. S. Lesne, C. Ali, C. Gabriel, N. Croci, E.T. MacKenzie, C.G. Glabe, M. Plotkine, C. Marchand-Verrecchia, D.Vivien and A. Buisson, NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production, J Neurosci 25(41) (2005), 9367-9377.
20. J. Li, M. Pankratz and J.A. Johnson, Differential gene expression patterns revealed by oligonucleotide versus long cDNA arrays, Toxicol Sci 69(2) (2002), 383-390.
21. R.J. Lipshutz, S.P. Fodor, T.R. Gingeras and D.J. Lockhart, High density synthetic oligonucleotide arrays, Nat Genet 21(1 Suppl) (1999), 20-24.
22. S.A. Lipton, Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond, Nat Rev Drug Discov 5(2) (2006), 160-170.
23. M. Liu, A. Sun, E.J. Shin, X. Liu, S.G. Kim, C.R. Runyons, W. Markesbery, H.C. Kim and G. Bing, Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin, Eur J Neurosci 23(8) (2006), 2027-2034.
24. W.J. Lukiw and N.G. Bazan, Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex, J Neurosci Res 50(6) (1997), 937-945.
25. W.J. Lukiw and N.G. Bazan, Strong nuclear factor-kappaB-DNA binding parallels cyclooxygenase-2 gene transcription in aging and in sporadic Alzheimer's disease superior temporal lobe neocortex, J Neurosci Res 53(5) (1998), 583-592.
26. G. Lynch, Memory enhancement: the search for mechanism-based drugs, Nat Neurosci 5 Suppl (2002), 1035-1038.
27. S. Marenco and D.R. Weinberger, Therapeutic potential of positive AMPA receptor modulators in the treatment of neuropsychiatric disorders, CNS Drugs 20 (2006), 173-185.
28. E. Masliah, M. Alford, M. Mallory, E. Rockenstein, D. Moechars and F. Van Leuven, Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice, Exp Neurol 163(2) (2000), 381-387.
29. D. Moechars, K. Lorent, B. De Strooper, I. Dewachter and F. Van Leuven, Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice, Embo J 15(6) (1996), 1265-1274.
30. P.K. Molsa, E. Sako, L. Paljarvi, J.O. Rinne and U.K. Rinne, Alzheimer's disease: neuropathological correlates of cognitive and motor disorders, Acta Neurol Scand 75(6) (1987), 376-384.
31. L.G. Puskas, A. Zvara, L. Hackler, Jr. and P. Van Hummelen, RNA amplification results in reproducible microarray data with slight ratio bias, Biotechniques 32(6) (2002), 1330-1334, 1336, 1338, 1340.
32. D. Rajagopalan, A comparison of statistical methods for analysis of high density oligonucleotide array data, Bioinformatics 19(12) (2003), 1469-1476.
33. P. Riederer and S. Hoyer, From benefit to damage. Glutamate and advanced glycation end products in Alzheimer brain, J Neural Transm 23 (2006), (Epub ahead of print).
34. S.W. Scheff and D.A. Price, Alzheimer's disease-related alterations in synaptic density: neocortex and hippocampus, J Alzheimers Dis 9(3 Suppl) (2006), 101-115.
35. H. Schulz, B. Weber and C. Wiedmann, Quantitative Real-Time PCR - Eine Frage der Normalisierung, BIO Spektrum 1(2004), 99-101.
36. J. Svaren, T. Ehrig, S.A. Abdulkadir, M.U. Ehrengruber, M.A. Watson and J. Milbrandt, EGR1 target genes in prostate carcinoma cells identified by microarray analysis, J Biol Chem 275(49) (2000), 38524-38531.
37. L.A. Ugozzoli, D. Chinn and K. Hamby, Fluorescent multicolor multiplex homogeneous assay for the simultaneous analysis of the two most common hemochromatosis mutations, Anal Biochem 307(1) (2002), 47-53.
38. I.I.Vandenbroucke, J. Vandesompele, A.D. Paepe and L. Messiaen, Quantification of splice variants using real-time PCR, Nucleic Acids Res 29(13) (2001), E68-8.
39. J. Vandesompele, A. De Paepe and F. Speleman, Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR, Anal Biochem 303(1) (2002), 95-98.
40. J. Vandesompele, K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe and F. Speleman, Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes, Genome Biol 3(7) (2002), RESEARCH0034.
41. G. Verdile, A. Gnjec, J. Miklossy, J. Fonte, G. Veurink, K. Bates, B. Kakulas, P.D. Mehta, E.A. Milward, N. Tan, R. Lareu, D. Lim, A. Dharmarajan and R.N. Martins, Protein markers for Alzheimer disease in the frontal cortex and cerebellum, Neurology 63(8) (2004), 1385-1392.
42. Q. Wang, S. Yu, A. Simonyi, G.Y. Sun and A.Y. Sun, Kainic Acid-mediated excitotoxicity as a model for neurodegeneration, Mol Neurobiol 31(1-3) (2005), 3-16.
43. C. Zoia, T. Cogliati, E. Tagliabue, G. Cavaletti, G. Sala, G. Galimberti, I. Rivolta, V. Rossi, L. Frattola and C. Ferrarese, Glutamate transporters in platelets: EAAT1 decrease in aging and in Alzheimer's disease, Neurobiol Aging 25(2) (2004), 149-157.