Memantine treatment decreases levels of secreted Alzheimer's amyloid precursor protein (APP) and amyloid beta (Aβ) peptide in the human neuroblastoma cells

Neuroscience Letters

Volumn 470, Issue 1, 2010, Pages 1-5

  Ray, Balmiki ^a   Banerjee, Pradeep K ^b   Greig, Nigel H ^c   Lahiri, Debomoy K ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FOREST RESEARCH INSTITUTE   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Alzheimer's drug; Amyloid; beta Peptide; Dementia; Neuronal cells; Protein processing; sAPP; Secretase; Tissue culture

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; ISOPROTEIN; MEMANTINE; SECRETASE;

ALZHEIMER DISEASE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG BINDING SITE; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MEMANTINE; NEUROBLASTOMA; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; PROTEIN ISOFORMS; RECEPTORS, CELL SURFACE; TIME FACTORS;

EID: 74149089703     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.11.016     Document Type: Article

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