Early impairment of long-term depression in the perirhinal cortex of a mouse model of Alzheimer's disease

Rejuvenation Research

Volumn 15, Issue 2, 2012, Pages 231-234

  Tamagnini, Francesco ^a   Burattini, Costanza ^a   Casoli, Tiziana ^b   Balietti, Marta ^b   Fattoretti, Patrizia ^b   Aicardi, Giorgio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b INRCA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LONG TERM DEPRESSION; MEMORY DISORDER; MOUSE; NONHUMAN; PERIRHINAL CORTEX; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; VISUAL MEMORY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN MAPPING; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ELECTROPHYSIOLOGY; LONG-TERM SYNAPTIC DEPRESSION; MEMORY; MICE; MICE, TRANSGENIC; NEURONAL PLASTICITY; SYNAPTIC TRANSMISSION; TIME FACTORS;

ANIMALIA; MUS;

EID: 84860274804     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2011.1311     Document Type: Article

References (20)

1. Wimo A, Prince M. Alzheimer's Disease International - World Alzheimer Report 2010 - The Global Economic Impact of Dementia. Available at www.alz.co.uk/research/ world-report/. Accessed January 19, 2012
2. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 2002;297:353-356
3. Walsh DM, Selkoe DJ. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 2004;44: 181-193
4. Blennow K, de Leon MJ, Zetterberg H. Alzheimer's disease. Lancet 2006;368:387-403
5. Ash KH, Zahs KR. Probing the biology of Alzheimer's disease in mice. Neuron 2010;66:631-645
6. Mullan M, Crawford F, Axelman K, Houlden H, Lilius L, Winblad B, Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nat Genet 1992;1:345-347
7. Mustafiz T, Portelius E, Gustavsson MK, HölttäM, Zetterberg H, Blennow K, Nordberg A, Unger Lithner C. Characterization of the brain b-amyloid isoform pattern at different ages of Tg2576 mice. Neurodegener Dis 2011;8:352-363
8. Jacobsen JS, Wu CC, Redwine JM, Comery TA, Arias R, Bowlby M, Martone R, Morrison JH, Pangalos MN, Reinhart PH, Bloom FE. Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 2006;103:5161-5166
9. Taglialatela G, Hogan D, Zhang WR, Dineley KT. Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition. Behav Brain Res 2009;200:95-99
10. Brown MW, Aggleton JP. Recognition memory: What are the roles of the perirhinal cortex and hippocampus? Nat Rev Neurosci 2001;2:51-61
11. Warburton EC, Koder T, Cho K, Massey PV, Duguid G, Barker GR, Aggleton JP, Bashir ZI, Brown MW. Cholinergic neurotransmission is essential for perirhinal cortical plasticity and recognition memory. Neuron 2003;38:987-996
12. Massey PV, Phythian D, Narduzzo K, Warburton EC, Brown MW, Bashir ZI. Learning-specific changes in longterm depression in adult perirhinal cortex. J Neurosci 2008; 28:7548-7554
13. Wolk DA, Signoff ED, Dekosky ST. Recollection and familiarity in amnestic mild cognitive impairment: A global decline in recognition memory. Neuropsychologia 2008;46: 1965-1978
14. Aicardi G, Argilli E, Cappello S, Santi S, Riccio M, Thoenen H, Canossa M. Induction of long-term potentiation and depression is reflected by corresponding changes in secretion of endogenous brain-derived neurotrophic factor. Proc Natl Acad Sci USA 2004;101:15788-15792
15. Palop JJ, Mucke L. Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks. Nat Neurosci 2010;13:812-818
16. Kim JH, Anwyl R, Suh YH, Djamgoz MB, Rowan MJ. Use-dependent effects of amyloidogenic fragments of (beta)- amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo. J Neurosci 2001;21:1327-1333
17. Hsieh H, Boehm J, Sato C, Iwatsubo T, Tomita T, Sisodia S, Malinow R. AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 2006; 52:831-843
18. Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ. Amyloidbeta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 2008;14:837-842
19. Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Soluble oligomers of amyloid beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 2009;62:788-801
20. Hsia AY, Masliah E, McConlogue L, Yu GQ, Tatsuno G, Hu K, Kholodenko D, Malenka RC, Nicoll RA, Mucke L. Plaqueindependent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci USA 1999;96: 3228-3233