TGF-β Signalling Is Required for CD4+ T Cell Homeostasis But Dispensable for Regulatory T Cell Function

PLoS Biology

Volumn 11, Issue 10, 2013, Pages

  Śledzińska, Anna ^a   Hemmers, Saskia ^b,g   Mair, Florian ^a   Gorka, Oliver ^c   Ruland, Jürgen ^c   Fairbairn, Lynsey ^d   Nissler, Anja ^a   Müller, Werner ^e,h   Waisman, Ari ^b,f   Becher, Burkhard ^a   Buch, Thorsten ^a,b,d  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF COLOGNE   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^f UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^g MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^h UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; AUTOINFLAMMATORY DISEASE; CD4+ T LYMPHOCYTE; CELL MATURATION; CELL PROLIFERATION; COLITIS; CONTROLLED STUDY; EFFECTOR CELL; HOMEOSTASIS; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LYMPHOCYTE FUNCTION; LYMPHOCYTE TRANSFER; LYMPHOCYTOPENIA; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; ORGANOGENESIS; PROTEIN EXPRESSION; RECEPTOR SENSITIVITY; REGULATORY T LYMPHOCYTE; THYMUS;

ANIMALS; AUTOIMMUNITY; CELL PROLIFERATION; COLITIS; GENE DELETION; HOMEOSTASIS; INFLAMMATION; INTEGRASES; LYMPHOPENIA; MICE; MICE, INBRED C57BL; NIH 3T3 CELLS; RECEPTORS, ANTIGEN, T-CELL; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TAMOXIFEN; THYMUS GLAND; TRANSFORMING GROWTH FACTOR BETA;

EID: 84886624251     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001674     Document Type: Article

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