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Volumn 197, Issue 9, 2003, Pages 1073-1081

Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis

Author keywords

Autoimmunity of CNS; Disease model; Experimental autoimmune encephalomyelitis; MOG; Multiple sclerosis

Indexed keywords

AUTOANTIGEN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; T LYMPHOCYTE RECEPTOR;

EID: 0038523790     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021603     Document Type: Article
Times cited : (680)

References (36)
  • 1
    • 0000742780 scopus 로고    scopus 로고
    • Pathology of multiple sclerosis
    • A. Compston, G. Ebers, H. Lassmann, I. McDonald, B. Matthews, and H. Wekerle, editors. Churchill Livingstone, Hong Kong
    • Lassmann, H. 1998. Pathology of multiple sclerosis. In McAlpine's Multiple Sclerosis. A. Compston, G. Ebers, H. Lassmann, I. McDonald, B. Matthews, and H. Wekerle, editors. Churchill Livingstone, Hong Kong. 323-358.
    • (1998) McAlpine's Multiple Sclerosis , pp. 323-358
    • Lassmann, H.1
  • 2
    • 0032859137 scopus 로고    scopus 로고
    • Long-term follow-up of isolated optic neuritis: The risk of developing multiple sclerosis, its outcome, and the prognostic role of paraclinical tests
    • Ghezzi, A., V. Martinelli, V. Torri, M. Zaffaroni, M. Rodegher, G. Comi, A. Zibetti, and N. Canal. 1999. Long-term follow-up of isolated optic neuritis: the risk of developing multiple sclerosis, its outcome, and the prognostic role of paraclinical tests. J. Neurol. 246:770-775.
    • (1999) J. Neurol. , vol.246 , pp. 770-775
    • Ghezzi, A.1    Martinelli, V.2    Torri, V.3    Zaffaroni, M.4    Rodegher, M.5    Comi, G.6    Zibetti, A.7    Canal, N.8
  • 3
    • 0034967936 scopus 로고    scopus 로고
    • Optic neuritis and multiple sclerosis
    • Soderstrom, M. 2001. Optic neuritis and multiple sclerosis. Acta Ophthalmol. Scand. 79:223-227.
    • (2001) Acta Ophthalmol. Scand. , vol.79 , pp. 223-227
    • Soderstrom, M.1
  • 4
    • 0022974996 scopus 로고
    • T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis
    • Zamvil, S.S., D.J. Mitchell, A.C. Moore, K. Kitamura, L. Steinman, and J.B. Rothbard. 1986. T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis. Nature. 324:258-260.
    • (1986) Nature , vol.324 , pp. 258-260
    • Zamvil, S.S.1    Mitchell, D.J.2    Moore, A.C.3    Kitamura, K.4    Steinman, L.5    Rothbard, J.B.6
  • 5
    • 0024504033 scopus 로고
    • Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice
    • Tuohy, V.K., Z. Lu, R.A. Sobel, R.A. Laursen, and M.B. Lees. 1989. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J. Immunol. 142: 1523-1527.
    • (1989) J. Immunol. , vol.142 , pp. 1523-1527
    • Tuohy, V.K.1    Lu, Z.2    Sobel, R.A.3    Laursen, R.A.4    Lees, M.B.5
  • 6
    • 0026777041 scopus 로고
    • Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice
    • Greer, J.M., V.K. Kuchroo, R.A. Sobel, and M.B. Lees. 1992. Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice. J. Immunol. 149:783-788.
    • (1992) J. Immunol. , vol.149 , pp. 783-788
    • Greer, J.M.1    Kuchroo, V.K.2    Sobel, R.A.3    Lees, M.B.4
  • 7
    • 0030029655 scopus 로고    scopus 로고
    • Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein
    • Greer, J.M., R.A. Sobel, A. Sette, S. Southwood, M.B. Lees, and V.K. Kuchroo. 1996. Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein. J. Immunol. 156:371-379.
    • (1996) J. Immunol. , vol.156 , pp. 371-379
    • Greer, J.M.1    Sobel, R.A.2    Sette, A.3    Southwood, S.4    Lees, M.B.5    Kuchroo, V.K.6
  • 8
    • 0029038922 scopus 로고
    • A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: Fine specificity and T cell receptor V beta expression of encephalitogenic T cells
    • Mendel, I., N. Kerlero de Rosbo, and A. Ben-Nun. 1995. A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells. Eur. J. Immunol. 25:1951-1959.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1951-1959
    • Mendel, I.1    Kerlero de Rosbo, N.2    Ben-Nun, A.3
  • 9
    • 0027193351 scopus 로고
    • T cells specific for the myelin oligodendrocyte glycoprotein mediate an unusual autoimmune inflammatory response in the central nervous system
    • Linington, C., T. Berger, L. Perry, S. Weerth, D. Hinze-Selch, Y. Zhang, H.C. Lu, H. Lassmann, and H. Wekerle. 1993. T cells specific for the myelin oligodendrocyte glycoprotein mediate an unusual autoimmune inflammatory response in the central nervous system. Eur. J. Immunol. 23: 1364-1372.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1364-1372
    • Linington, C.1    Berger, T.2    Perry, L.3    Weerth, S.4    Hinze-Selch, D.5    Zhang, Y.6    Lu, H.C.7    Lassmann, H.8    Wekerle, H.9
  • 10
    • 0028006884 scopus 로고
    • Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice
    • Amor, S., N. Groome, C. Linington, M.M. Morris, K. Dornmair, M.V. Gardinier, J.M. Matthieu, and D. Baker. 1994. Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice. J. Immunol. 153:4349-4356.
    • (1994) J. Immunol. , vol.153 , pp. 4349-4356
    • Amor, S.1    Groome, N.2    Linington, C.3    Morris, M.M.4    Dornmair, K.5    Gardinier, M.V.6    Matthieu, J.M.7    Baker, D.8
  • 11
    • 0028965522 scopus 로고
    • Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)-derived peptide: Preliminary analysis of MOG T cell epitopes
    • Kerlero de Rosbo, N., I. Mendel, and A. Ben-Nun. 1995. Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)-derived peptide: preliminary analysis of MOG T cell epitopes. Eur. J. Immunol. 25:985-993.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 985-993
    • Kerlero de Rosbo, N.1    Mendel, I.2    Ben-Nun, A.3
  • 12
    • 0030561151 scopus 로고    scopus 로고
    • Allergic encephalomyelitis in common marmosets: Pathogenesis of a multiple sclerosis-like lesion
    • Genain, C.P., and S.L. Hauser. 1996. Allergic encephalomyelitis in common marmosets: pathogenesis of a multiple sclerosis-like lesion. Methods. 10:420-434.
    • (1996) Methods , vol.10 , pp. 420-434
    • Genain, C.P.1    Hauser, S.L.2
  • 13
    • 0028828168 scopus 로고
    • The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat
    • Adelmann, M., J. Wood, I. Benzel, P. Fiori, H. Lassmann, J.M. Matthieu, M.V. Gardinier, K. Dornmair, and C. Linington. 1995. The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat. J. Neuroimmunol. 63:17-27.
    • (1995) J. Neuroimmunol. , vol.63 , pp. 17-27
    • Adelmann, M.1    Wood, J.2    Benzel, I.3    Fiori, P.4    Lassmann, H.5    Matthieu, J.M.6    Gardinier, M.V.7    Dornmair, K.8    Linington, C.9
  • 14
    • 0027144752 scopus 로고
    • Reactivity to myelin antigens in multiple sclerosis. Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein
    • Kerlero de Rosbo, N., R. Milo, M.B. Lees, D. Burger, C.C. Bernard, and A. Ben-Nun. 1993. Reactivity to myelin antigens in multiple sclerosis. Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein. J. Clin. Invest. 92:2602-2608.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2602-2608
    • Kerlero de Rosbo, N.1    Milo, R.2    Lees, M.B.3    Burger, D.4    Bernard, C.C.5    Ben-Nun, A.6
  • 16
    • 0030961807 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis: The antigen specificity of T lymphocytes determines the topography of lesions in the central and peripheral nervous system
    • Berger, T., S. Weerth, K. Kojima, C. Linington, H. Wekerle, and H. Lassmann. 1997. Experimental autoimmune encephalomyelitis: the antigen specificity of T lymphocytes determines the topography of lesions in the central and peripheral nervous system. Lab. Invest. 76:355-364.
    • (1997) Lab. Invest. , vol.76 , pp. 355-364
    • Berger, T.1    Weerth, S.2    Kojima, K.3    Linington, C.4    Wekerle, H.5    Lassmann, H.6
  • 17
    • 0018883441 scopus 로고
    • Optic neuritis and chronic relapsing experimental allergic encephalomyelitis: Relationship to clinical course and comparison with multiple sclerosis
    • Raine, C.S., U. Traugott, R.B. Nussenblatt, and S.H. Stone. 1980. Optic neuritis and chronic relapsing experimental allergic encephalomyelitis: relationship to clinical course and comparison with multiple sclerosis. Lab. Invest. 42:327-335.
    • (1980) Lab. Invest. , vol.42 , pp. 327-335
    • Raine, C.S.1    Traugott, U.2    Nussenblatt, R.B.3    Stone, S.H.4
  • 18
    • 0019479134 scopus 로고
    • Experimental allergic encephalomyelitis. I. Optic nerve and central nervous system manifestations
    • Hayreh, S.S., R.M. Massanari, T. Yamada, and S.M. Hayreh. 1981. Experimental allergic encephalomyelitis. I. Optic nerve and central nervous system manifestations. Invest. Ophthalmol. Vis. Sci. 21:256-269.
    • (1981) Invest. Ophthalmol. Vis. Sci. , vol.21 , pp. 256-269
    • Hayreh, S.S.1    Massanari, R.M.2    Yamada, T.3    Hayreh, S.M.4
  • 19
    • 0019441080 scopus 로고
    • Experimental allergic encephalomyelitis. II. Retinal and other ocular manifestations
    • Hayreh, S.S. 1981. Experimental allergic encephalomyelitis. II. Retinal and other ocular manifestations. Invest. Ophthalmol. Vis. Sci. 21:270-281.
    • (1981) Invest. Ophthalmol. Vis. Sci. , vol.21 , pp. 270-281
    • Hayreh, S.S.1
  • 20
    • 0031941202 scopus 로고    scopus 로고
    • Optic neuritis in chronic relapsing experimental allergic encephalomyelitis in Biozzi ABH mice: Demyelination and fast axonal transport changes in disease
    • O'Neill, J.K., D. Baker, M.M. Morris, S.E. Gschmeissner, H.G. Jenkins, A.M. Butt, S.L. Kirvell, and S. Amor. 1998. Optic neuritis in chronic relapsing experimental allergic encephalomyelitis in Biozzi ABH mice: demyelination and fast axonal transport changes in disease. J. Neuroimmunol. 82:210-218.
    • (1998) J. Neuroimmunol. , vol.82 , pp. 210-218
    • O'Neill, J.K.1    Baker, D.2    Morris, M.M.3    Gschmeissner, S.E.4    Jenkins, H.G.5    Butt, A.M.6    Kirvell, S.L.7    Amor, S.8
  • 21
    • 0031859926 scopus 로고    scopus 로고
    • Microvascular and cellular responses in the optic nerve of rats with acute experimental allergic encephalomyelitis (EAE)
    • Hu, P., J. Pollard, N. Hunt, J. Taylor, and T. Chan-Ling. 1998. Microvascular and cellular responses in the optic nerve of rats with acute experimental allergic encephalomyelitis (EAE). Brain Pathol. 8:475-486.
    • (1998) Brain Pathol. , vol.8 , pp. 475-486
    • Hu, P.1    Pollard, J.2    Hunt, N.3    Taylor, J.4    Chan-Ling, T.5
  • 22
    • 0028102655 scopus 로고
    • High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
    • Lafaille, J.J., K. Nagashima, M. Katsuki, and S. Tonegawa. 1994. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell. 78:399-408.
    • (1994) Cell. , vol.78 , pp. 399-408
    • Lafaille, J.J.1    Nagashima, K.2    Katsuki, M.3    Tonegawa, S.4
  • 23
    • 0027468174 scopus 로고
    • Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity
    • Goverman, J., A. Woods, L. Larson, L.P. Weiner, L. Hood, and D.M. Zaller. 1993. Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell. 72:551-560.
    • (1993) Cell. , vol.72 , pp. 551-560
    • Goverman, J.1    Woods, A.2    Larson, L.3    Weiner, L.P.4    Hood, L.5    Zaller, D.M.6
  • 24
    • 0034724441 scopus 로고    scopus 로고
    • Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor
    • Waldner, H., M.J. Whitters, R.A. Sobel, M. Collins, and V.K. Kuchroo. 2000. Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. Proc. Natl. Acad. Sci. USA. 97:3412-3417.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3412-3417
    • Waldner, H.1    Whitters, M.J.2    Sobel, R.A.3    Collins, M.4    Kuchroo, V.K.5
  • 26
    • 0028946480 scopus 로고
    • Cassette vectors directing expression of T cell receptor genes in transgenic mice
    • Kouskoff, V., K. Signorelli, C. Benoist, and D. Mathis. 1995. Cassette vectors directing expression of T cell receptor genes in transgenic mice. J. Immunol. Methods. 180:273-280.
    • (1995) J. Immunol. Methods , vol.180 , pp. 273-280
    • Kouskoff, V.1    Signorelli, K.2    Benoist, C.3    Mathis, D.4
  • 27
    • 0021177812 scopus 로고
    • A novel myelin-associated glycoprotein defined by a mouse monoclonal antibody
    • Linington, C., M. Webb, and P.L. Woodhams. 1984. A novel myelin-associated glycoprotein defined by a mouse monoclonal antibody. J. Neuroimmunol. 6:387-396.
    • (1984) J. Neuroimmunol. , vol.6 , pp. 387-396
    • Linington, C.1    Webb, M.2    Woodhams, P.L.3
  • 28
    • 0025261029 scopus 로고
    • The immune response to myelin proteolipid protein in the Lewis rat: Identification of the immunodominant B cell epitope
    • Gunn, C.A., M.K. Richards, and C. Linington. 1990. The immune response to myelin proteolipid protein in the Lewis rat: identification of the immunodominant B cell epitope. J. Neuroimmunol. 27:155-162.
    • (1990) J. Neuroimmunol. , vol.27 , pp. 155-162
    • Gunn, C.A.1    Richards, M.K.2    Linington, C.3
  • 29
    • 0032532313 scopus 로고    scopus 로고
    • Expression of autoimmune disease-related antigens by cells of the immune system
    • Mor, F., G.L. Boccaccio, and T. Unger. 1998. Expression of autoimmune disease-related antigens by cells of the immune system. J. Neurosci. Res. 54:254-262.
    • (1998) J. Neurosci. Res. , vol.54 , pp. 254-262
    • Mor, F.1    Boccaccio, G.L.2    Unger, T.3
  • 30
    • 0035171545 scopus 로고    scopus 로고
    • Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
    • Derbinski, J., A. Schulte, B. Kyewski, and L. Klein. 2001. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol. 2:1032-1039.
    • (2001) Nat. Immunol. , vol.2 , pp. 1032-1039
    • Derbinski, J.1    Schulte, A.2    Kyewski, B.3    Klein, L.4
  • 31
    • 0035877212 scopus 로고    scopus 로고
    • MHC class II-regulated central nervous system autoaggression and T cell responses in peripheral lymphoid tissues are dissociated in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis
    • Weissert, R., K.L. de Graaf, M.K. Storch, S. Barth, C. Linington, H. Lassmann, and T. Olsson. 2001. MHC class II-regulated central nervous system autoaggression and T cell responses in peripheral lymphoid tissues are dissociated in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. J. Immunol. 166:7588-7599.
    • (2001) J. Immunol. , vol.166 , pp. 7588-7599
    • Weissert, R.1    De Graaf, K.L.2    Storch, M.K.3    Barth, S.4    Linington, C.5    Lassmann, H.6    Olsson, T.7
  • 32
    • 0345628025 scopus 로고    scopus 로고
    • Optic neuritis: Prognosis for multiple sclerosis from MRI, CSF, and HLA findings
    • Soderstrom, M., J. Ya-Ping, J. Hillert, and H. Link. 1998. Optic neuritis: prognosis for multiple sclerosis from MRI, CSF, and HLA findings. Neurology. 50:708-714.
    • (1998) Neurology , vol.50 , pp. 708-714
    • Soderstrom, M.1    Ya-Ping, J.2    Hillert, J.3    Link, H.4
  • 34
    • 0034255884 scopus 로고    scopus 로고
    • Genetic and epigenetic influence on EAE phenotypes induced with different encephalitogenic peptides
    • Sobel, R.A. 2000. Genetic and epigenetic influence on EAE phenotypes induced with different encephalitogenic peptides. J. Neuroimmunol. 108:45-52.
    • (2000) J. Neuroimmunol. , vol.108 , pp. 45-52
    • Sobel, R.A.1
  • 35
    • 0033920968 scopus 로고    scopus 로고
    • A neuropathological analysis of experimental autoimmune encephalomyelitis with predominant brain stem and cerebellar involvement and differences between active and passive induction
    • Muller, D.M., M.P. Pender, and J.M. Greer. 2000. A neuropathological analysis of experimental autoimmune encephalomyelitis with predominant brain stem and cerebellar involvement and differences between active and passive induction. Acta Neuropathol. (Berl.). 100:174-182.
    • (2000) Acta Neuropathol. (Berl.) , vol.100 , pp. 174-182
    • Muller, D.M.1    Pender, M.P.2    Greer, J.M.3
  • 36
    • 0036481263 scopus 로고    scopus 로고
    • Epitope spreading in immune-mediated diseases: Implications for immunotherapy
    • Vanderlugt, C.L., and S.D. Miller. 2002. Epitope spreading in immune-mediated diseases: implications for immunotherapy. Nat. Rev. Immunol. 2:85-95.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 85-95
    • Vanderlugt, C.L.1    Miller, S.D.2


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