Dendritic cell-specific disruption of TGF-β receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity

Journal of Immunology

Volumn 189, Issue 8, 2012, Pages 3878-3893

  Ramalingam, Rajalakshmy ^a   Larmonier, Claire B ^a   Thurston, Robert D ^a   Midura Kiela, Monica T ^a   Zheng, Song Guo ^b   Ghishan, Fayez K ^a   Kiel, Pawel R ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; INDOLEAMINE 2,3 DIOXYGENASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; B LYMPHOCYTE ACTIVATION; CD25- FOXP3+ REGULATORY T LYMPHOCYTE; CELL EXPANSION; CELL SPECIFICITY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; GENE; GENE DELETION; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; KNOCKOUT MOUSE; LYMPHOID ORGAN; MOUSE; MULTIORGAN AUTOIMMUNE INFLAMMATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; SPONTANEOUS MULTIORGAN AUTOIMMUNITY; T LYMPHOCYTE ACTIVATION; TGFBR2 GENE;

ANIMALS; AUTOIMMUNE DISEASES; COLITIS; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; IMMUNE TOLERANCE; IMMUNOPHENOTYPING; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; ORGAN SPECIFICITY; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; T-LYMPHOCYTES, REGULATORY;

EID: 84867290406     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201029     Document Type: Article

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