Bioactive Peptides and Proteins from Fish Muscle and Collagen

Bioactive Proteins and Peptides as Functional Foods and Nutraceuticals

Volumn , Issue , 2010, Pages 203-223

  Howell, Nazlin K ^a   Kasase, Chitundu ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

ACE inhibition mechanism; ACE inhibitory peptides derived from fish proteins; ACE inhibitory peptides isolated from fish proteins; Bioactive peptides and proteins from fish muscle and collagen; Common synthetic antioxidants in food systems, with phenolic group(s); Enzymatic hydrolysates from walleye pollack; Fish gelatin; Fish myofibrillar proteins displaying excellent gelation and emulsifying properties; in vitro ACE inhibition by peptides from fish proteins

Indexed keywords

EID: 84886534978     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780813811048.ch14     Document Type: Chapter

References (151)

1. Abbey LD, Johnson P-NT, Howell NK. 2008. Characterisation of the gelatin of the flying guardard (Dactylopterus volitans) and its interaction with starch. African J Food Science 2: 131-135.
2. Alghazeer R, Howell NK. 2008. Formation of 4-hydroxynonenal (4-HNE) in frozen mackerel (Scomber scombrus) in the presence and absence of green tea. J Sci Food Agric 88 (7): 1128-1134.
3. Amarowicz R, Shahidi F. 1997. Antioxidant activity of peptide fractions of capelin protein hydrolysates. Food Chem 58: 355-359.
4. Aoki H, Ahsan MN, Watabe S. 2003. Molecular cloning and functional characterization of crustapain: A distinct cysteine proteinase with unique substrate specificity from northern shrimp Pandalus borealis. J Biochem 133 (6): 799-810.
5. Ariyoshi Y. 1993. Angiotensin-converting enzyme inhibitors derived from food proteins. Trends Food Sci Technol 4: 139-144.
6. Arnesen JA, Gildberg A. 2002. Preparation and characterisation of gelatin from the skin of harp seal (phoca groendlandica). Bioresource Technol 82: 191-194.
7. Aruoma OI, Halliwell B, Hoey BM, Butler J. 1988. The antioxidant action of taurine, hypotaurine and their metabolic precursors . J Biochem 256 (25): 1-255.
8. Aruoma OI, Laughton MI, Halliwell B. 1989. Camosine, homocamosine and serine, could they act as antioxidants in vivo? J Biochem 264: 863-869.
9. Astawan M, Wahyuni M, Yasuhara T, Yamada K, Tadokoro T, Maekawa A. 1995. Effects of angiotensin I-converting enzyme inhibitory substances derived from Indonesian dried-salted fish on blood pressure of rats. Biosci Biotechnol Biochem 59 (3): 425-429.
10. Badii F, Howell NK. 2006. Fish gelatin: Structure, gelling properties and interaction with egg albumen proteins. Food Hydrocolloids 20 (5): 630-640.
11. Balian G, Bowes JH. 1977. The structure and properties of collagen . In: AG Ward, A Courts, eds., The Science and Technology of Gelatin, 1-27. London: Academic Press.
12. Beldent VA, Michaud L, Wei MT, Chauvet PC. 1993. Proteolytic release of human angiotensin converting enzyme: Localization of the cleavage site. J Biol Chem 268: 26428-26434.
13. Bella J, Eaton M, Brodsky B, Berman HM. 1994. Crystal-structure and molecular-structure of a collagen-like peptide at 1.9-angstrom resolution. Science 266: 75-81.
14. Beutner S, Bloedorn B, Frixel S, Hernández Blanco I, Hoffmann T, Martin HD, Mayer B, Noack P, Ruck C, Schmidt M, Schülke I, Sell S, Ernst H, Haremza S, Seybold G, Sies H, Stahl W, Walsh R. 2001. Quantitative assessment of antioxidant properties of natural colorants and phytochemicals: Carotenoids, flavonoids, phenols and indigoids. The role of β-carotene in antioxidant functions. J Agric Food Chem 81: 559-568.
15. Bishov SJ, Henick AS. 1975. Antioxidant effect of protein hydrolyzates in freeze-dried model system. Synergistic action with a series of phenolic antioxidants. J Food Sci 40: 345-348.
16. Bougatef A, Hajji M, Balti R, Lassoued I, Triki-Ellouz Y, Nasri M. 2009. Antioxidant and free radical-scavenging activities of smooth hound (Mustelus mustelus) muscle protein hydrolysates obtained by gastrointestinal proteases. Food Chem 114: 1198-1205.
17. Byun HG, Kim SK. 2001. Purification and characterization of angiotensin I converting enzyme (ACE) inhibitory peptides from Alaska pollack (Theragra chalcogramma) skin. Proc Biochem 36: 1155-1162.
18. Byun HG. 2002. Structure and activity of angiotensin I converting enzyme inhibitory peptides derived from Alaskan pollack skin. J Biochem Mol Biol 35: 239-243.
19. Caldwell PRB, Seegal BC, Hsu KC, Das M, Soffer RL. 1976. Angiotensin-converting enzyme: Vascular endothelial localization . Science 191: 1050-1051.
20. Carlsen CU, Rasmussen KT, Kjeldsen KK, Westergaard P, Skibsted LH. 2003. Pro-and antioxidative activity of protein fractions from pork (Longissimus dorsi). Eur Food Res Technol 217: 195-200.
21. Chen HM, Muramoto K, Yamauchi F. 1995. Structural analysis of antioxidative peptides from soybean conglycinin. J Agric Food Chem 43: 574-578.
22. Chen HM, Muramoto K, Yamauchi F, Nokihara K. 1996. Antioxidant activity of designed peptides based on the antioxidative peptide derived from digests of a soybean peptide. J Agric Food Chem 44: 2619-2623.
23. Chen KM, Decker EM. 1994. Endogenous skeletal muscle antioxidants . Crit Rev Food Sci Nutr 34: 403-426.
24. Cheow CS, Norizah MS, Kyaw ZY, Howell NK. 2007. Preparation and characterisation of gelatins from the skins of sin croaker (Johnius dussumieri) and shortfin scad (Decapterus macrosoma). Food Chem 101: 386-391.
25. Cheung HS, Wang FL, Ondetti MA, Sabo EF, Cushman DW. 1980. Binding of peptide substrates and inhibitors of angiotensin-converting enzyme: Importance of the COOH-terminal dipeptide sequence. Biological Chem 255: 401-405.
26. Choi SS, Regenstein JM. 2000. Physico-chemical and sensory characteristics of fish gelatin. J Food Sci 65: 194-199.
27. Chuang WL, Pan BS, Tsai JS. 2000. Inhibition of lipoxygenase and blood thinning effects of mackerel protein hydrolysate. J Food Biochem 24: 333-343.
28. Clare DA, Swaisgood HE. 2000. Bioactive milk peptides: A prospectus. J Dairy Sci 83 (6): 1187-1195.
29. Collins A. 2005. Antioxidant intervention as a route to cancer prevention. Eur J Cancer 41: 1923-1930.
30. Davalos A, Miguel M, Bartolome B, López-Fandiño R. 2004. Antioxidant activity of peptides derived from egg white proteins by enzymatic hydrolysis. J Food Prot 67: 1939-1944.
31. De Mejia E, De Lumen BO. 2006. Soybean bioactive peptides: A new horizon in preventing chronic diseases. Sexuality Reprod Menop 4 (20): 91-95.
32. Dendorfer A, Wolfrum S, Wellhoner P, Korsman K, Dominiak P. 1997. Intravascular and interstitial degradation of bradykinin in isolated perfused rat heart. Brit J Pharmac 122: 1179-1187.
33. Eastoe JE, Leach AA. 1977. The chemical constitution of gelatin. In: AG Ward, A Courts, eds., The Science and Technology of Gelatin, 73-107. London: Academic Press.
34. Enari H, Takahashi Y, Kawarasaki M, Tada M, Tatsuta K. 2008. Identification of angiotensin I-converting enzyme inhibitory peptides derived from salmon muscle and their antihypertensive effect. Fisheries Sci 74: 911-920.
35. Fahmi A, Morimura S, Guob HC, Shigematsu T, Kida K, Uemurac Y. 2004. Production of angiotensin I converting enzyme inhibitory peptides from sea bream scales. Proc Biochem 39: 1195-1200.
36. Ferreira SH, Bartet DC, Greene LJ. 1970. Isolation of bradykinin-potentiating peptides from bothrops jararaca venom. Biochem 9: 2583-2593.
37. Flory PJ, Weaver ES. 1960. Helix, coil transition in dilute aqueous collagen solution, J Amer Chem Soc 82: 4518-4525.
38. Frankel EN. 1999. Food antioxidants and phytochemicals: Present and future perspectives. Fett/Lipid 101 (12): 450.
39. Frankel EN. 1998. Lipid Oxidation. Dundee, UK: Oily Press. Friedman M. 1996. Nutritional value of proteins from different food sources. A review. J Agric Food Chem 44: 6-29.
40. Fujita H, Yokoyama K, Yoshikawa M. 2000. Classification and antihypertensive activity of angiotensin-I-converting enzyme inhibitory activity derived from food proteins. J Food Sci 65: 564-569.
41. Fujita H, Yoshikawa M. 1999. LKPNM: A prodrug-type ACE inhibitory peptide derived from fish protein. Immunopharmacol 44: 123-127.
42. Gilsenan PM, Ross-Murphy SB. 2000. Rheological characterisation of gelatins from mammalian and marine sources. Food Hydrocolloid 14: 191-195.
43. Giménez B, Alemán A, Montero P, Gómez-Guillén MC. 2009. Antioxidant and functional properties of gelatin hydrolysates obtained from skin of sole and squid. Food Chem 114: 976-983.
44. Gobbetti M, Minervini F, Rizzello CG. 2004. Angiotensin I-converting-enzyme-inhibitory and antimicrobial bioactive peptides. Intl J Dairy Technol 57 (2/3): 173-188.
45. Gordon MH. 1990. The mechanisms of antioxidant action in vitro. In: BJF Hudson, ed., Food Antioxidants, 1-18. New York: Elsevier Applied Science.
46. Hall C. 2001. Sources of natural antioxidants: Oilseeds, nuts, cereals, legumes, animal products and microbial sources. In: J Pokorny, N Yanishlieva, M Gordon, eds., Antioxidants in Food: Practical Applications, 159-209. Cambridge, England: Woodhead Publishing Limited.
47. Halliwell B. 2000. Lipid peroxidation, antioxidants and cardiovascular disease: How should we move forward? Cardiovascular Res 47: 410-418.
48. Halliwell B, Whiteman M. 2004. Measuring reactive species and oxidative damage in vivo and in cell culture: How should you do it and what do the results mean? Brit J Pharmaco 142: 231-255.
49. Hinterwaldner R. 1977. Technology of gelatine manufacture. In: AG Ward, A Courts, eds., The Science and Technology of Gelatin, 315-364. London: Academic Press.
50. Hopia AI, Huang SW, Frankel EN. 1996. Effect of α-tocopherol and trolox on the decomposition of methyl linoleate hydroperoxides . Lipids 31: 357-365.
51. Howell NK, Saeed S. 1999. The effect of antioxidants on the production of lipid oxidation products and transfer of free radicals in oxidised lipid-protein systems. In: TK Basu, NJ Temple, ML Garg, eds., Antioxidants in Human Health and Disease, 43-54. Oxford: CAB International.
52. Hultin HO. 1994. Oxidation of lipids in seafoods. In: F Shahidi, JR Botta, eds., Seafoods: Chemistry, Processing Technology and Quality, 49. London: Blackie Academic & Professional. Inagami T. 1992. The renin-angiotensin system. Essays Biochem 28: 147-164.
53. Intarasirisawat R, Benjakul S, Visessanguan W, Prodpran T, Tanaka M, Howell NK. 2007. Autolysis study of bigeye snapper (Priacanthus macracanthus) skin and its effect on gelatine. Food Hydrocolloids 21: 537-544.
54. Itou K, Akahane Y. 2004. Antihypertensive effect of heshiko, a fermented mackerel product, on spontaneously hypertensive rats. Fish Sci 70: 1121-1129.
55. Iwami K, Hattori M, Ibuki F. 1987. Prominent antioxidant effect of wheat gliadine on linoleate peroxidation in powder model systems at high water activity. J Agric Food Chem 35: 628-631.
56. Jao CL, Ko WC. 2002. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging by protein hydrolysates from tuna cooking juice. Fish Sci 68: 430-435.
57. Je JY, Park PJ, Kim SK. 2005. Antioxidant activity of peptide isolated from Alaska pollack (Theragra chalcogramma) frame protein hydrolysate. Food Res Intl 38: 45-50.
58. Je JY, Pyo J, Park PJ, Kwon JY, Kim SK. 2004. A novel angiotensin I converting enzyme inhibitory peptide from Alaska pollack (Theragra chalcogramma) frame protein hydrolysate. J Agric Food Chem 52: 7842-7845.
59. Je JY, Qian ZJ, Byun HG, Kim SK. 2007. Purification and characterization of an antioxidant peptide obtained from tuna backbone protein by enzymatic hydrolysis. Proc Biochem 42: 840-846.
60. Johnston-Bank FA. 1983. From tannery to table: An account of gelatin production. J Soc Leather Technol Chem 68: 141-145.
61. Jun SY, Park PJ, Jung WK, Kim SK. 2004. Purification and characterization of an antioxidative peptide from enzymatic hydrolysate of yellowfin sole (Limanda aspera) frame protein. Eur Food Res Techol 219: 20-26.
62. Jung MY, Kim SK, Kim SY. 1995. Riboflavin-sensitized photooxidation of ascorbic acid: Kinetics and amino acid effects. Food Chem 53: 397-403.
63. Jung WK, Mendis E, Je JY, Park PJ, Son BW, Kim HC, Choi YK, Kim SK. 2006. Angiotensin I-converting enzyme inhibitory peptide from yellowfin sole (Limanda aspera) frame protein and its antihypertensive effect in spontaneously hypertensive rats. J Food Chem 94: 26-32.
64. Jung WK, Qian ZJ, Lee SH, Choi SY, Sung NJ, Byun HG, Kim SK. 2007. Free radical scavenging activity of a novel antioxidative peptide isolated from in vitro gastrointestinal digests of Mytilus coruscus. J Med Food 10: 197-202.
65. Kanner J. 1979. S-Nitrosocysteine (RSNO) an effective antioxidant in cured meat. J Amer Oil Chem Soc 56: 74-76.
66. Kawasaki T, Seki E, Osajima K, Yoshida M, Asada K, Matsui T, Osajima Y. 2000. Antihypertensive effect of Valyl-Tyrosine, a short chain peptide derived from sardine muscle hydrolyzate, on mild hypertensive subjects. J Hypertens 14: 519-523.
67. Kawashima K, Itoh H, Miyoshi M, Chibata I. 1979. Antioxidant properties of branched-chain amino acid derivatives. Chem Pharmacol Bull 27: 1912-1916.
68. Kelleher K. 2005. Discards in the world's marine fisheries-An update. FAO Fisheries Technical Paper 470. Rome: Fishing Technology Service, FAO Fisheries Department.
69. Kim SK, Kim YY, Byun KS, Nam DSJ, Shahidi F. 2001. Isolation and characterization of antioxidative peptides from gelatin hydrolysate of Alaska pollack skin. J Agric Food Chem 49: 1984-1989.
70. Klompong V, Benjakul S, Kantachote D, Shahidi F. 2007. Antioxidative activity and functional properties of protein hydrolysate of yellow stripe trevally (Selaroides leptolepis) as influenced by the degree of hydrolysis and enzyme type. Food Chem 102: 1317-1327.
71. Kohama Y, Matsumoto S, Oka H, Teramoto T, Okabe M, Mimura T. 1988. Isolation of angiotensin-converting enzyme inhibitor from tuna muscle. Biochem Biophys Res Commn 155: 332-337.
72. Kokkonen JO, Lindstedt KA, Kuoppala A, Kovanen PT. 2000. Kinin-degrading pathways in the human heart. T Cardiovascular Med 10: 42-45.
73. Kong B, Xiong YL. 2006. Antioxidant activity of zein hydrolysates in a liposome system and the possible mode of action. J Agric Food Chem 54: 6059-6068.
74. Korhonen H, Pihlanto A. 2003. Food-derived bioactive peptides -opportunities for designing future foods. Cur Pharm Design 9: 1297-1308.
75. Kristjánsson MM, Guthmundsdóttir S, Fox JW, Bjarnason JB. 1995. Characterization of a collagenolytic serine proteinase from the Atlantic cod (gadus morhua). Comp Biochem Physiol B Biochem Mol Biol 110 (4): 701-707.
76. Laakso S. 1984. Inhibition of lipid peroxidation by casein. Evidence of molecular encapsulation of 4,4-pentadiene fatty acids. Biochim et Biophys Acta 792: 11-15.
77. Laurence DR, Bennett PN, Brown MJ. 1997. Clinical Pharmacology, 8th ed. New York: Churchill Livingstone. Lawrie RA. 1991. Meat Science, 5th ed. Oxford: Pergamon Press.
78. Lin L, Li BF. 2006. Radical scavenging properties of protein hydrolysates from Jumbo flying squid (Dosidicus eschrichitii Steenstrup) skin gelatin. J Sci Food Agric 86: 2290-2295.
79. Mäkinen EM, Hopia AI. 2000. Effects of α-tocopherol and ascorbyl palmitate on the isomerization and decomposition of methyl linoleate hydroperoxides. Lipids 35: 1215-1223.
80. Marcuse R. 1960. Antioxidant effect of amino acids. Nature 186: 886-887.
81. Matsufuji H, Matsui T, Ohshige S, Kawasaki T, Osajima K, Osajima Y. 1995. Antihypertensive effects of angiotensin fragments in SHR. Biosci Biotech Biochem 59: 1398-1401.
82. Matsufuji H, Matsui T, Seki E, Osajima K, Nakashima M, Osajima Y. 1994. Angiotensin I-converting enzyme inhibitory peptides in an alkaline protease hydrolyzate derived from sardine muscle. Biosci Biotechnol Biochem 58: 2244-2245.
83. Matsui T, Matsufuji H, Seki E, Osajima K, Nakashima M, Osajima Y. 1993. Inhibition of angiotensin I-converting enzyme by Bacillus licheniformis alkaline protease hydrolyzates derived from sardine muscle. Biosci Biotechnol Biochem 57: 922-925.
84. Matsumura N, Fujii M, Takeda Y, Sugita K, Shimizu T. 1993. Angiotensin-I-converting enzyme inhibitory peptides derived from bonito bowels autolysate. Biosci Biotechnol Biochem 57: 695-697.
85. Meisel H. 1997. Biochemical properties of bioactive peptides derived from milk proteins: Potential nutraceuticals for food and pharmaceutical applications. Livestock Prod Sci 50: 125-138.
86. Meisel H. 1993. Casokinins as bioactive peptides in the primary structure of casein. In: KD Schwenke, R Mothes, eds., Food Proteins-Structure Functionality, 67-75. New York: Weinheim VCH.
87. Meisel H, Walsh DJ, Murray B, FitzGerald RJ. 2006. ACE inhibitory peptides. In: Y Mine, F Shahidi, eds., Nutraceutical Proteins and Peptides in Health and Disease, 269-318. Boca Raton, FL: Taylor & Francis Group.
88. Mendis E, Rajapakse N, Kim SK. 2005. Antioxidant properties of a radical-scavenging peptide purified from enzymatically prepared fish skin gelatin hydrolysate. J Agric Food Chem 53: 581-587.
89. Merzametov MM, Gadzhieva LI. 1976. Certain amino acids as antioxidants in butter fat. Zzv Ucheb Zaved Pischew Technol 115: 21-27.
90. Mine Y, Shahidi F. 2006. ACE inhibitory peptides. In: Y Mine, F Shahidi, eds., Nutraceutical Proteins and Peptides in Health and Disease, 269-318. Boca Raton, FL: Taylor & Francis Group.
91. Montero P, Borderias J. 1989. Distribution and hardness of muscle connective tissue in hake (Merluccius merluccius L.) and trout (Salmo irideus Gibb). Z Lebensm Unters Forsch 189: 530-533.
92. Montero P, Gomez-Guillen MC. 2000. Extracting conditions for Megrim (Lepidorhombus boscii) skin collagen affect functional properties of the resulting gelatin. Food Chem Toxicol 65: 434-438.
93. Moskaug JO. 2001. Biological activity of flavonoids. Lipidforum Nytt/News 61: 13.
94. Mozaffarian D, Katan MB, Ascherio A, Stampfer MJ, Willett WC. 2006. Trans fatty acids and cardiovascular disease. New J Eur Med 354 (15): 1601-1613.
95. Nagai T, Nagashima T, Abe A, Suzuki N. 2006. Antioxidative activities and angiotensin I-converting enzyme inhibition of extracts prepared from chum salmon (Oncorhynchus keta) cartilage and skin. Intl J Food Properties 9 (4): 813-822.
96. Nagai T, Suzuki N, Tanoue Y, Kai N, Nagashima T. 2007. Physical properties of kamaboko derived from walleye pollack (Theragra chalcogramma) surimi and functional properties of its enzymatic hydrolysates. J Food Agric Env 5: 76-81.
97. Nakajima K, Yoshie YS, Ogushi M. 2009. Comparison of ACE inhibitory and DPPH radical scavenging activities of fish muscle hydrolysates. Food Chem 114: 844-851.
98. Natesh R, Schwager SLU, Sturrock ED, Acharya R. 2003. Crystal structure of the human angiotensin-converting enzyme-lisinopril complex. Nature 421: 551-554.
99. Ng KKF, Vane JR. 1968. Fate of angiotensin I in the circulation. Nature 218: 144-150.
100. Nomura A, Noda N, Maruyama S. 2002. Purification of angiotensin I-converting enzyme inhibitors in pelagic thresher Alopias pelagicus muscle hydrolysate and viscera extracts. Fisheries Sci 68: 954-956.
101. Norziah MH, Al-Hassan A, Khairulnizam AB, Mordi MN, Norita M. 2009. Characterization of fish gelatin from surimi processing wastes: Thermal analysis and effect of transglutaminase on gel properties. Food Hydrocol 23 (6): 1610-1616.
102. Okamoto A, Hanagata H, Matsumuto E, Kawamura Y, Koizumi Y, Yanagida F. 1995. Angiotensin I converting enzyme inhibitory activities of various fermented foods. Biosci Biotech Biochem 59 (6): 1147-1149.
103. Ondetti MA, Cushman DW. 1982. Enzymes of the renin-angiotensin system and their inhibitors. Annu Rev Biochem 51: 283-308.
104. Ondetti MA, Rubin B, Cushman DW. 1977. Design of specific inhibitors of angiotensin-converting enzyme: New class of orally active antihypertensive agents. Science 196: 441-444.
105. Ondetti MA, Williams NJ, Sabo EF, PluBc'ec J, Weaver ER, Kocy O. 1971. Angiotensin-converting enzyme inhibitors from the venom of Buthrups jararaca. Isolation, elucidation of structure, and synthesis. Biochem Nature 19: 22.
106. Ono S, Hosokawa M, Miyashita K, Takahashi K. 2006. Inhibition properties of dipeptides from salmon muscle hydrolysate on angiotensin I-converting enzyme. Intl J Food Sci Technol 41: 383-386.
107. Ono S. 2003. Isolation of peptides with angiotensin I-converting enzyme inhibitory effect derived from hydrolysate of upstream chum salmon muscle. J Food Sci 68 (5): 1611-1614.
108. Philips MI. 1987. Functions of angiotensin in the central nervous system. Annu Rev Physiol 49: 413-435.
109. Piez KA, Sherman MR. 1970. Characterization of product formed renaturation of alphal-CB2, a small peptide from collagen. Biochem 9: 4129-4134.
110. Pihlanto A. 2006. Antioxidative peptides derived from milk proteins . Intl Dairy J 16: 1306-1314.
111. Porter NA, Caldwell SEI, Kills KA. 1995. Mechanism of free radical oxidation of unsaturated lipids. Lipids 30: 277-290.
112. Privalov PL. 1982. Stability of proteins-proteins which do not present a single cooperative system. Adv Protein Chem 35: 1-104.
113. Privalov PL, Serdyuk IN, Tiktopulo EI. 1971. Thermal conformational transformations of tropocollagen 2. Viscometric and light-scattering studies. Biopolymers 10: 1777.
114. Privalov PL, Tiktopulo EI. 1970. Thermal conformational transformation of tropocollagen 1. Calorimetric study. Biopolymers 9: 127.
115. Rajapakse N, Mendis E, Byun HG, Kim SK. 2005. Purification and in vitro antioxidative effects of giant squid muscle peptides on free radical-mediated oxidative systems. J Nutr Biochem 16: 562-569.
116. Ren J, Zhao M, Shi J, Wang J, Jiang Y, Cui C, Kakuda Y, Xue SJ. 2008. Purification and identification of antioxidant peptides from grass carp muscle hydrolysates by consecutive chromatography and electrospray ionization-mass spectrometry. Food Chem 108: 727-736.
117. Revankar GD. 1974. Proline as an antioxidant in fish oil. J Food Sci Technol 11: 1-11.
118. Rhee KS, Ziprin YA, Rhee KC. 1979. Water-soluble antioxidant activity of oilseed protein derivatives in model lipid peroxidation systems of meat. J Food Sci 44: 1132-1135.
119. Riison T, Sims RJ, Fioriti JA. 1980. Effect of amino acids on the autoxidaton of safflower oil in emulsions. J Amer Oil Chem Soc 57: 354-359.
120. Rother J. 1995. Edible gelatin types, use and application in the food industry. Food Technol Eur 32-42.
121. Saeed S, Gillies D, Wagner G, Howell NK. 2006. ESR and NMR spectroscopy studies on protein oxidation and formation of dityrosine in emulsions containing oxidised methyl linoleate. Food Chem Toxicol 44 (8): 1385-1392.
122. Saiga A, Tanabe S, Nishimura T. 2003. Antioxidant activity of peptides obtained from porcine myofibrillar proteins by protease treatment. J Agric Food Chem 51: 3661-3667.
123. Saito M, Sato K, Kunisaki N, Kimura S. 2000. Characterization of a rainbow trout matrix metalloproteinase capable of degrading type I collagen. Eur J Biochem 267: 6943-6950.
124. Sakanaka S, Tachibana Y, Ishihara N, Juneja LR. 2004. Antioxidant activity of egg-yolk protein hydrolysates in a linoleic acid oxidation system. Food Chem 86: 99-103.
125. Sarabia AI, Gomez-Guillen MC, Montero P. 2000. The effect of added salts on the viscoelastic properties of fish skin gelatin. Food Chem 70: 71-76.
126. Sathivel S, Bechtel PJ, Babbitt J, Smiley S, Crapo C, Reppond KD. 2003. Biochemical and functional properties of herring (Clupea harengus) byproduct hydrolysates. J Food Sci 68: 2196-2200.
127. Sato K, Yoshinaka R, Sato M. 1989. Hydroxyproline content in the acid-soluble collagen from muscle of several fishes. Bull Jpn Soc Sci Fish 55: 1467.
128. Shahidi F. 1994. Seafood processing by-products. In: F Shahidi, JR Botta, eds., Seafoods: Chemistry, Processing Technology and Quality, 320-334. London: Blackie Academic and Professional.
129. Shahidi F, Amarowicz R. 1996. Antioxidant activity of protein hydrolyzates from aquatic species. J Amer Oil Chem Soc 73: 1197-1199.
130. Sikorski ZE, Kotakowska A, Burt JR. 1990. Postharvest biochemical and microbial changes. In: ZE Sikorski, ed., Seafood: Resources, Nutritional Composition, and Preservation, 191-213. Boca Raton, FL: CRC Press.
131. Sims RJ, Fioriti JA. 1977. Methional as an antioxidant for vegetable oils. J Amer Oil Chem Soc 54: 4-7.
132. Sovik SL, Rustard T. 2006. Effect of season and fishing ground on the activity of cathepsin B and collagenase in by-products from cod species. LWT-Food Sci Technol 39: 43-53.
133. Suetsuna K, Osajima K. 1986. The inhibitory activities against angiotensin I converting enzyme of basic peptides originating from sardine and hair tail meat. Nippon Suisan Gakkaishi 52: 1981-1984.
134. Suetsuna K, Ukeda H, Ochi H. 2000. Isolation and characterization of free radical scavenging activities peptides derived from casein. J Nutritional Biochem 11: 128-131.
135. te Nijenhuis K. 1997. Gelatin. Adv Polymer Sci 160-193.
136. Thakur S, Vadolas D, Germann HP, Heidemann E. 1986. Influence of different tripeptides on the stability of the collagen triple helix 2. An experimental approach with appropriate variations of trimer model oligotripeptide. Biopolymers 25: 1081-1086.
137. Thiansilakul Y, Benjakul S, Shahidi F. 2007. Antioxidative activity of protein hydrolysate from round scad muscle using alcalase and Flavourzyme. J Food Biochem 31: 266-287.
138. Venugopal MG, Ramshaw JAM, Braswell E, Zhu D, Brodsky B. 1994. Electrostatic interactions in collagen-like triple-helical peptides. Biochem 33: 7948.
139. Vercruysse L, Smagghe G, Herregods G, Van Camp J. 2005. ACE inhibitory activity in enzymatic hydrolysates of insect protein. J Agric Food Chem 53: 5207-5211.
140. Vermeirssen V. 2003. Release and activity of ACE inhibitory peptides from pea and whey protein: Fermentation in vitro digestion and transport. PhD dissertation, Ghent University, Belgium.
141. Vermeirssen V, Van Camp J, Verstraete W. 2004. Bioavailability of angiotensin I converting enzyme inhibitory peptides. British J Nutr 92: 357-366.
142. Wainewright FW. 1977. Physical tests for gelatin and gelatin products. In: AG Ward, A Courts, eds., The Science and Technology of Gelatin, 507-534. London: Academic Press.
143. Wako Y, Ishikawa S, Muramoto K. 1996. Angiotensin I-converting enzyme inhibitors in autolysates of squid liver and mantle muscle. Biosci Biotechnol Biochem 60 (8): 1353-1355.
144. Wang JY, Fujimoto K, Miyazawa T, Endo Y. 1991. Antioxidative mechanism of maize zein in powder model systems against methyl linoleate: Effect of water activity and coexistence of antioxidants. J Agric Food Chem 39: 351-355.
145. Wei L, Clauser E, Alhenc-Gelas F, Corvol P. 1992. The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors. J Biol Chem 267: 13398-13405.
146. Willcox JK, Ash SL, Catignani G. 2004. Antioxidants and prevention of chronic disease. Crit Rev Food Sci Nutr 44: 275-295.
147. Wu HC, Chen HM, Shiau CY. 2003. Free amino acids and peptides as related to antioxidant properties in protein hydrolysates of mackerel (Scomber austriasicus). Food Res Intl 36: 949-957.
148. Yanishlieva-Maslarova NV. 2001. Sources of natural antioxidants: Vegetables, fruits, herbs, spices and teas. In J Pokorny, N Yanishlieva, M Gordon, eds., Antioxidants in Food, chap. 10. Boca Raton, FL: CRC Press.
149. Yokoyama K, Chiba H, Yoshikawa M. 1992. Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci Biotechnol Biochem 56: 1541-1545.
150. Yoshikawa M, Fujita H, Matoba N, Takenaka Y, Yamamoto T, Yamauchi R, Tsuruki H, Tahahata K. 2000. Bioactive peptides derived from food proteins preventing lifestyle related diseases . Biofactors 12: 143-146.
151. Yoshinaka R, Sato K, Anbe H, Sato M, Shimizu Y. 1988. Distribution of collagen in body muscle of fishes with different swimming modes. Comp Biochem Physiol 89B: 147-151.