-
3
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding HP, Zhang Y, Ron D: Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 1999, 397:271-274
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
4
-
-
0023852783
-
The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins
-
Kozutsumi Y, Segal M, Normington K, Gething MJ, Sambrook J: The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 1988, 332:462-464
-
(1988)
Nature
, vol.332
, pp. 462-464
-
-
Kozutsumi, Y.1
Segal, M.2
Normington, K.3
Gething, M.J.4
Sambrook, J.5
-
5
-
-
24344489466
-
The unfolded protein response is activated in Alzheimer's disease
-
Hoozemans JJ, Veerhuis R, Van Haastert ES, Rozemuller JM, Baas F, Eikelenboom P, Scheper W: The unfolded protein response is activated in Alzheimer's disease. Acta Neuropathol (Berl) 2005,110:165-172
-
(2005)
Acta Neuropathol (Berl)
, vol.110
, pp. 165-172
-
-
Hoozemans, J.J.1
Veerhuis, R.2
Van Haastert, E.S.3
Rozemuller, J.M.4
Baas, F.5
Eikelenboom, P.6
Scheper, W.7
-
6
-
-
35848951621
-
Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner
-
Chafekar SM, Hoozemans JJ, Zwart R, Baas F, Scheper W: Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner. Antioxid Redox Signal 2007, 9:2245-2254
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2245-2254
-
-
Chafekar, S.M.1
Hoozemans, J.J.2
Zwart, R.3
Baas, F.4
Scheper, W.5
-
7
-
-
53649085618
-
Increased Abeta1-42 production sensitizes neuroblastoma cells for ER stress toxicity
-
Chafekar SM, Zwart R, Veerhuis R, Vanderstichele H, Baas F, Scheper W: Increased Abeta1-42 production sensitizes neuroblastoma cells for ER stress toxicity. Curr Alzheimer Res 2008, 5:469-474
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 469-474
-
-
Chafekar, S.M.1
Zwart, R.2
Veerhuis, R.3
Vanderstichele, H.4
Baas, F.5
Scheper, W.6
-
8
-
-
14044261099
-
Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3
-
Kim AJ, Shi Y, Austin RC, Werstuck GH: Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. J Cell Sci 2005, 118:89-99
-
(2005)
J Cell Sci
, vol.118
, pp. 89-99
-
-
Kim, A.J.1
Shi, Y.2
Austin, R.C.3
Werstuck, G.H.4
-
9
-
-
0037160134
-
Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation
-
Song L, De Sarno P, Jope RS: Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation. J Biol Chem 2002, 277:44701-44708
-
(2002)
J Biol Chem
, vol.277
, pp. 44701-44708
-
-
Song, L.1
De Sarno, P.2
Jope, R.S.3
-
10
-
-
0442276554
-
The glamour and gloom of glycogen synthase kinase-3
-
Jope RS, Johnson GV: The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci 2004, 29:95-102
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 95-102
-
-
Jope, R.S.1
Johnson, G.V.2
-
11
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H, Braak E: Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl) 1991, 82:239-259
-
(1991)
Acta Neuropathol (Berl)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
12
-
-
0019967975
-
The Global Deterioration Scale for assessment of primary degenerative dementia
-
Reisberg B, Ferris SH, de Leon MJ, Crook T: The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry 1982, 139:1136-1139
-
(1982)
Am J Psychiatry
, vol.139
, pp. 1136-1139
-
-
Reisberg, B.1
Ferris, S.H.2
de Leon, M.J.3
Crook, T.4
-
13
-
-
0025264054
-
Distinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain
-
Yamaguchi H, Haga C, Hirai S, Nakazato Y, Kosaka K: Distinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain. Acta Neuropathol (Berl) 1990,79:569-572
-
(1990)
Acta Neuropathol (Berl)
, vol.79
, pp. 569-572
-
-
Yamaguchi, H.1
Haga, C.2
Hirai, S.3
Nakazato, Y.4
Kosaka, K.5
-
14
-
-
33749150163
-
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
-
Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K: Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol2006, 112:389-404
-
Acta Neuropathol2006
, vol.112
, pp. 389-404
-
-
Braak, H.1
Alafuzoff, I.2
Arzberger, T.3
Kretzschmar, H.4
Del Tredici, K.5
-
15
-
-
33846577831
-
Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain
-
Sokka AL, Putkonen N, Mudo G, Pryazhnikov E, Reijonen S, Khiroug L, Belluardo N, Lindholm D, Korhonen L: Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain. J Neurosci 2007, 27:901-908
-
(2007)
J Neurosci
, vol.27
, pp. 901-908
-
-
Sokka, A.L.1
Putkonen, N.2
Mudo, G.3
Pryazhnikov, E.4
Reijonen, S.5
Khiroug, L.6
Belluardo, N.7
Lindholm, D.8
Korhonen, L.9
-
16
-
-
45549103421
-
AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response
-
Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W: AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J Biol Chem 2008, 283:11905-11912
-
(2008)
J Biol Chem
, vol.283
, pp. 11905-11912
-
-
Luo, D.1
He, Y.2
Zhang, H.3
Yu, L.4
Chen, H.5
Xu, Z.6
Tang, S.7
Urano, F.8
Min, W.9
-
17
-
-
33846605587
-
Activation of the unfolded protein response in Parkinson's disease
-
Hoozemans JJ, Van Haastert ES, Eikelenboom P, de Vos RA, Rozemuller JM, Scheper W: Activation of the unfolded protein response in Parkinson's disease. Biochem Biophys Res Commun 2007, 354:707-711
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 707-711
-
-
Hoozemans, J.J.1
Van Haastert, E.S.2
Eikelenboom, P.3
de Vos, R.A.4
Rozemuller, J.M.5
Scheper, W.6
-
18
-
-
24644488688
-
The unfolded protein response in vanishing white matter disease
-
van der Voorn JP, van Kollenburg B, Bertrand G, Van Haren K, Scheper GC, Powers JM, van der Knaap MS: The unfolded protein response in vanishing white matter disease. J Neuropathol Exp Neurol 2005, 64:770-775
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 770-775
-
-
van der Voorn, J.P.1
van Kollenburg, B.2
Bertrand, G.3
Van Haren, K.4
Scheper, G.C.5
Powers, J.M.6
van der Knaap, M.S.7
-
19
-
-
0030000867
-
Comparison of the neurofi- brillary pathology in Alzheimer's disease and familial presenile dementia with tangles
-
Spillantini MG, Crowther RA, Goedert M: Comparison of the neurofi- brillary pathology in Alzheimer's disease and familial presenile dementia with tangles. Acta Neuropathol 1996, 92:42-48
-
(1996)
Acta Neuropathol
, vol.92
, pp. 42-48
-
-
Spillantini, M.G.1
Crowther, R.A.2
Goedert, M.3
-
20
-
-
14244260720
-
Required techniques and useful molecular markers in the neuropathologic diagnosis of neurodegenerative diseases
-
Dickson DW: Required techniques and useful molecular markers in the neuropathologic diagnosis of neurodegenerative diseases. Acta Neuropathol 2005, 109:14-24
-
(2005)
Acta Neuropathol
, vol.109
, pp. 14-24
-
-
Dickson, D.W.1
-
21
-
-
0035919837
-
Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies
-
Kuusisto E, Salminen A, Alafuzoff I: Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies. Neuroreport 2001, 12:2085-2090
-
(2001)
Neuroreport
, vol.12
, pp. 2085-2090
-
-
Kuusisto, E.1
Salminen, A.2
Alafuzoff, I.3
-
22
-
-
0036284021
-
Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: Possible role in tangle formation
-
Kuusisto E, Salminen A, Alafuzoff I: Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation. Neuropathol Appl Neurobiol 2002, 28:228-237
-
(2002)
Neuropathol Appl Neurobiol
, vol.28
, pp. 228-237
-
-
Kuusisto, E.1
Salminen, A.2
Alafuzoff, I.3
-
23
-
-
0036942638
-
The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease
-
Leroy K, Boutajangout A, Authelet M, Woodgett JR, Anderton BH, Brion JP: The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease. Acta Neuropathol (Berl) 2002, 103:91-99
-
(2002)
Acta Neuropathol (Berl)
, vol.103
, pp. 91-99
-
-
Leroy, K.1
Boutajangout, A.2
Authelet, M.3
Woodgett, J.R.4
Anderton, B.H.5
Brion, J.P.6
-
24
-
-
33749143839
-
Multispectral imaging in biology and medicine: Slices of life
-
Levenson RM, Mansfield JR: Multispectral imaging in biology and medicine: slices of life. Cytometry A 2006, 69:748-758
-
(2006)
Cytometry A
, vol.69
, pp. 748-758
-
-
Levenson, R.M.1
Mansfield, J.R.2
-
25
-
-
0026051511
-
Reexam- ination of granulovacuolar degeneration
-
Okamoto K, Hirai S, Iizuka T, Yanagisawa T, Watanabe M: Reexam- ination of granulovacuolar degeneration. Acta Neuropathol (Berl) 1991, 82:340-345
-
(1991)
Acta Neuropathol (Berl)
, vol.82
, pp. 340-345
-
-
Okamoto, K.1
Hirai, S.2
Iizuka, T.3
Yanagisawa, T.4
Watanabe, M.5
-
26
-
-
0037077040
-
Toxic proteins in neurodegenera- tive disease
-
Taylor JP, Hardy J, Fischbeck KH: Toxic proteins in neurodegenera- tive disease. Science 2002, 296:1991-1995
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
27
-
-
0001521232
-
Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains
-
Perry G, Friedman R, Shaw G, Chau V: Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc Natl Acad Sci USA 1987, 84:3033-3036
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 3033-3036
-
-
Perry, G.1
Friedman, R.2
Shaw, G.3
Chau, V.4
-
28
-
-
0017645498
-
Granulovacuolar degeneration in the ageing brain and in dementia
-
Ball MJ, Lo P: Granulovacuolar degeneration in the ageing brain and in dementia. J Neuropathol Exp Neurol 1977, 36:474-487
-
(1977)
J Neuropathol Exp Neurol
, vol.36
, pp. 474-487
-
-
Ball, M.J.1
Lo, P.2
-
29
-
-
0026454255
-
Granulovacuolar degeneration in the hippocampal cortex of aging and demented patients-a quantitative study
-
Xu M, Shibayama H, Kobayashi H, Yamada K, Ishihara R, Zhao P, Takeuchi T, Yoshida K, Inagaki T, Nokura K: Granulovacuolar degeneration in the hippocampal cortex of aging and demented patients-a quantitative study. Acta Neuropathol (Berl) 1992, 85:1-9
-
(1992)
Acta Neuropathol (Berl)
, vol.85
, pp. 1-9
-
-
Xu, M.1
Shibayama, H.2
Kobayashi, H.3
Yamada, K.4
Ishihara, R.5
Zhao, P.6
Takeuchi, T.7
Yoshida, K.8
Inagaki, T.9
Nokura, K.10
-
30
-
-
33749579383
-
ER stress triggers autoph- agy
-
Yorimitsu T, Nair U, Yang Z, Klionsky DJ: ER stress triggers autoph- agy. J Biol Chem 2006, 281:30299-30304
-
(2006)
J Biol Chem
, vol.281
, pp. 30299-30304
-
-
Yorimitsu, T.1
Nair, U.2
Yang, Z.3
Klionsky, D.J.4
-
31
-
-
49949105827
-
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
-
Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS: The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell Death Differ 2008, 15:1460-1471
-
(2008)
Cell Death Differ
, vol.15
, pp. 1460-1471
-
-
Li, J.1
Ni, M.2
Lee, B.3
Barron, E.4
Hinton, D.R.5
Lee, A.S.6
-
32
-
-
33845480131
-
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
-
Bernales S, McDonald KL, Walter P: Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol 2006, 4:e423
-
(2006)
PLoS Biol
, vol.4
-
-
Bernales, S.1
McDonald, K.L.2
Walter, P.3
-
33
-
-
34248581851
-
ER-phagy: Selective autophagy of the endoplasmic reticulum
-
Bernales S, Schuck S, Walter P: ER-phagy: selective autophagy of the endoplasmic reticulum. Autophagy 2007, 3:285-287
-
(2007)
Autophagy
, vol.3
, pp. 285-287
-
-
Bernales, S.1
Schuck, S.2
Walter, P.3
-
34
-
-
0023793690
-
Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases
-
Manetto V, Perry G, Tabaton M, Mulvihill P, Fried VA, Smith HT, Gambetti P, Autilio-Gambetti L: Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases. Proc Natl Acad Sci USA 1988, 85:4501-4505
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 4501-4505
-
-
Manetto, V.1
Perry, G.2
Tabaton, M.3
Mulvihill, P.4
Fried, V.A.5
Smith, H.T.6
Gambetti, P.7
Autilio-Gambetti, L.8
-
35
-
-
0023917701
-
Alz-50, ubiquitin and tau immunoreactivity of neurofibrillary tangles, Pick bodies and Lewy bodies
-
Love S, Saitoh T, Quijada S, Cole GM, Terry RD: Alz-50, ubiquitin and tau immunoreactivity of neurofibrillary tangles, Pick bodies and Lewy bodies. J Neuropathol Exp Neurol 1988, 47:393-405
-
(1988)
J Neuropathol Exp Neurol
, vol.47
, pp. 393-405
-
-
Love, S.1
Saitoh, T.2
Quijada, S.3
Cole, G.M.4
Terry, R.D.5
-
36
-
-
0035153961
-
Perisomatic granules (non-plaque dystrophic dendrites) of hippocampal CA1 neurons in Alzheimer's disease and Pick's disease: A lesion distinct from granu- lovacuolar degeneration
-
Probst A, Herzig MC, Mistl C, Ipsen S, Tolnay M: Perisomatic granules (non-plaque dystrophic dendrites) of hippocampal CA1 neurons in Alzheimer's disease and Pick's disease: a lesion distinct from granu- lovacuolar degeneration. Acta Neuropathol 2001, 102:636-644
-
(2001)
Acta Neuropathol
, vol.102
, pp. 636-644
-
-
Probst, A.1
Herzig, M.C.2
Mistl, C.3
Ipsen, S.4
Tolnay, M.5
-
37
-
-
0029894586
-
Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain
-
Joung I, Strominger JL, Shin J: Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain. Proc Natl Acad Sci USA 1996, 93:5991-5995
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5991-5995
-
-
Joung, I.1
Strominger, J.L.2
Shin, J.3
-
38
-
-
0030911597
-
Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein
-
Puls A, Schmidt S, Grawe F, Stabel S: Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein. Proc Natl Acad Sci USA 1997, 94:6191-6196
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6191-6196
-
-
Puls, A.1
Schmidt, S.2
Grawe, F.3
Stabel, S.4
-
40
-
-
0035896518
-
The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor
-
Wooten MW, Seibenhener ML, Mamidipudi V, Diaz-Meco MT, Barker PA, Moscat J: The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor. J Biol Chem 2001, 276:7709-7712
-
(2001)
J Biol Chem
, vol.276
, pp. 7709-7712
-
-
Wooten, M.W.1
Seibenhener, M.L.2
Mamidipudi, V.3
Diaz-Meco, M.T.4
Barker, P.A.5
Moscat, J.6
-
41
-
-
20044367108
-
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
-
Andorfer C, Acker CM, Kress Y, Hof PR, Duff K, Davies P: Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J Neurosci 2005, 25:5446-5454
-
(2005)
J Neurosci
, vol.25
, pp. 5446-5454
-
-
Andorfer, C.1
Acker, C.M.2
Kress, Y.3
Hof, P.R.4
Duff, K.5
Davies, P.6
-
42
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
Santacruz K, Lewis J, Spires T, Paulson J, Kotilinek L, Ingelsson M, Guimaraes A, DeTure M, Ramsden M, McGowan E, Forster C, Yue M, Orne J, Janus C, Mariash A, Kuskowski M, Hyman B, Hutton M, Ashe KH: Tau suppression in a neurodegenerative mouse model improves memory function. Science 2005, 309:476-481
-
(2005)
Science
, vol.309
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McGowan, E.10
Forster, C.11
Yue, M.12
Orne, J.13
Janus, C.14
Mariash, A.15
Kuskowski, M.16
Hyman, B.17
Hutton, M.18
Ashe, K.H.19
-
43
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
Yoshiyama Y, Higuchi M, Zhang B, Huang SM, Iwata N, Saido TC, Maeda J, Suhara T, Trojanowski JQ, Lee VM: Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 2007, 53:337-351
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.M.4
Iwata, N.5
Saido, T.C.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.10
-
44
-
-
49149083015
-
Evidence that non-fibrillar tau causes pathology linked to neurodegeneration and behavioral impairments
-
Brunden KR, Trojanowski JQ, Lee VM: Evidence that non-fibrillar tau causes pathology linked to neurodegeneration and behavioral impairments. J Alzheimers Dis 2008, 14:393-399
-
(2008)
J Alzheimers Dis
, vol.14
, pp. 393-399
-
-
Brunden, K.R.1
Trojanowski, J.Q.2
Lee, V.M.3
-
45
-
-
0025736490
-
Expression of heat shock proteins in Alzheimer's disease
-
Hamos JE, Oblas B, Pulaski-Salo D, Welch WJ, Bole DG, Drachman DA: Expression of heat shock proteins in Alzheimer's disease. Neurology 1991, 41:345-350
-
(1991)
Neurology
, vol.41
, pp. 345-350
-
-
Hamos, J.E.1
Oblas, B.2
Pulaski-Salo, D.3
Welch, W.J.4
Bole, D.G.5
Drachman, D.A.6
-
46
-
-
33744985455
-
Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo
-
Unterberger U, Hoftberger R, Gelpi E, Flicker H, Budka H, Voigtlander T: Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo. J Neuropathol Exp Neurol 2006, 65:348-357
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 348-357
-
-
Unterberger, U.1
Hoftberger, R.2
Gelpi, E.3
Flicker, H.4
Budka, H.5
Voigtlander, T.6
-
47
-
-
0030769092
-
Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
-
Cook DG, Forman MS, Sung JC, Leight S, Kolson DL, Iwatsubo T, Lee VM, Doms RW: Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells. Nat Med 1997, 3:1021-1023
-
(1997)
Nat Med
, vol.3
, pp. 1021-1023
-
-
Cook, D.G.1
Forman, M.S.2
Sung, J.C.3
Leight, S.4
Kolson, D.L.5
Iwatsubo, T.6
Lee, V.M.7
Doms, R.W.8
-
48
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides
-
Hartmann T, Bieger SC, Bruhl B, Tienari PJ, Ida N, Allsop D, Roberts GW, Masters CL, Dotti CG, Unsicker K, Beyreuther K: Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med 1997, 3:1016-1020
-
(1997)
Nat Med
, vol.3
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
Bruhl, B.3
Tienari, P.J.4
Ida, N.5
Allsop, D.6
Roberts, G.W.7
Masters, C.L.8
Dotti, C.G.9
Unsicker, K.10
Beyreuther, K.11
-
49
-
-
50949097728
-
Oligomer-specific Abeta toxicity in cell models is mediated by selective uptake
-
Chafekar SM, Baas F, Scheper W: Oligomer-specific Abeta toxicity in cell models is mediated by selective uptake. Biochim Biophys Acta 2008, 1782:523-531
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 523-531
-
-
Chafekar, S.M.1
Baas, F.2
Scheper, W.3
-
50
-
-
0348010382
-
Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neuro- toxicity
-
Suen KC, Yu MS, So KF, Chang RC, Hugon J: Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neuro- toxicity. J Biol Chem 2003, 278:49819-49827
-
(2003)
J Biol Chem
, vol.278
, pp. 49819-49827
-
-
Suen, K.C.1
Yu, M.S.2
So, K.F.3
Chang, R.C.4
Hugon, J.5
-
51
-
-
33746533924
-
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, Labaer J, Rochet JC, Bonini NM, Lindquist S: Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science 2006, 313:324-328
-
(2006)
Science
, vol.313
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
Haynes, C.M.4
Hill, K.J.5
Bhullar, B.6
Liu, K.7
Xu, K.8
Strathearn, K.E.9
Liu, F.10
Cao, S.11
Caldwell, K.A.12
Caldwell, G.A.13
Marsischky, G.14
Kolodner, R.D.15
Labaer, J.16
Rochet, J.C.17
Bonini, N.M.18
Lindquist, S.19
-
52
-
-
0037128935
-
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
-
Stamer K, Vogel R, Thies E, Mandelkow E, Mandelkow EM: Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol 2002, 156:1051-1063
-
(2002)
J Cell Biol
, vol.156
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.M.5
-
53
-
-
0034131044
-
Impaired proteasome function in Alzheimer's disease
-
Keller JN, Hanni KB, Markesbery WR: Impaired proteasome function in Alzheimer's disease. J Neurochem 2000, 75:436-439
-
(2000)
J Neurochem
, vol.75
, pp. 436-439
-
-
Keller, J.N.1
Hanni, K.B.2
Markesbery, W.R.3
-
54
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study
-
Nixon RA, Wegiel J, Kumar A, Yu WH, Peterhoff C, Cataldo A, Cuervo AM: Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J Neuropathol Exp Neurol 2005, 64:113-122
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
Yu, W.H.4
Peterhoff, C.5
Cataldo, A.6
Cuervo, A.M.7
-
55
-
-
45749114895
-
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice
-
Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T: The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest 2008, 118:2190-2199
-
(2008)
J Clin Invest
, vol.118
, pp. 2190-2199
-
-
Pickford, F.1
Masliah, E.2
Britschgi, M.3
Lucin, K.4
Narasimhan, R.5
Jaeger, P.A.6
Small, S.7
Spencer, B.8
Rockenstein, E.9
Levine, B.10
Wyss-Coray, T.11
-
56
-
-
28844475400
-
HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
-
Iwata A, Riley BE, Johnston JA, Kopito RR: HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. J Biol Chem 2005, 280:40282-40292
-
(2005)
J Biol Chem
, vol.280
, pp. 40282-40292
-
-
Iwata, A.1
Riley, B.E.2
Johnston, J.A.3
Kopito, R.R.4
-
57
-
-
24944482408
-
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation
-
Iwata A, Christianson JC, Bucci M, Ellerby LM, Nukina N, Forno LS, Kopito RR: Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation. Proc Natl Acad Sci USA 2005, 102:13135-13140
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13135-13140
-
-
Iwata, A.1
Christianson, J.C.2
Bucci, M.3
Ellerby, L.M.4
Nukina, N.5
Forno, L.S.6
Kopito, R.R.7
-
58
-
-
34548299555
-
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
-
Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM: Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007, 171:513-524
-
(2007)
Am J Pathol
, vol.171
, pp. 513-524
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Yoshimori, T.4
Stolz, D.B.5
Ron, D.6
Yin, X.M.7
-
59
-
-
33947497050
-
Differential effects of endoplasmic reticulum stress- induced autophagy on cell survival
-
Ding WX, Ni HM, Gao W, Hou YF, Melan MA, Chen X, Stolz DB, Shao ZM, Yin XM: Differential effects of endoplasmic reticulum stress- induced autophagy on cell survival. J Biol Chem 2007, 282: 4702-4710
-
(2007)
J Biol Chem
, vol.282
, pp. 4702-4710
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Hou, Y.F.4
Melan, M.A.5
Chen, X.6
Stolz, D.B.7
Shao, Z.M.8
Yin, X.M.9
|