메뉴 건너뛰기




Volumn 28, Issue 9, 2005, Pages 1073-1078

Mutant presenilin 2 increases acetylcholinesterase activity in neuronal cells

Author keywords

Acetylcholine esterase; Alzheimer's disease; Neuronal cell; Presenilin 2

Indexed keywords


EID: 26444585965     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02977404     Document Type: Article
Times cited : (4)

References (29)
  • 1
    • 0032080309 scopus 로고    scopus 로고
    • Stable complexes involving acetylcholinesterase and amyloid beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils
    • Alvarez, A., Alarcon, R., Opazo, C., Campos, E. O., Munoz, F.J., Calderon, F.H., Dajas, F., Gentry, M. K., Doctor, B. P., De Mello, F. G., and Inestrosa, N. C., Stable complexes involving acetylcholinesterase and amyloid beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils. J. Neurosci., 18, 3213-3223 (1999).
    • (1999) J. Neurosci. , vol.18 , pp. 3213-3223
    • Alvarez, A.1    Alarcon, R.2    Opazo, C.3    Campos, E.O.4    Munoz, F.J.5    Calderon, F.H.6    Dajas, F.7    Gentry, M.K.8    Doctor, B.P.9    De Mello, F.G.10    Inestrosa, N.C.11
  • 2
    • 0037133649 scopus 로고    scopus 로고
    • Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons
    • Alves da Costa, C., Paitel, E., Mattson, M. P., Amson, R., Telerman, A., Ancolio, K., and Checler, F., Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons. Proc. Natl. Acad. Sci. U.S.A., 99, 4043-4048 (2002).
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 4043-4048
    • Alves Da Costa, C.1    Paitel, E.2    Mattson, M.P.3    Amson, R.4    Telerman, A.5    Ancolio, K.6    Checler, F.7
  • 3
    • 0035659414 scopus 로고    scopus 로고
    • Pro apoptotic effect of presenilin 2 (PS2) overexpression is associated with down regulation of Bcl2 in cultured neurons
    • Araki, W., Yuasa, K., Takeda, S., Takeda, K., Shirotani, K., Takahashi, K., and Tabira, T., Pro apoptotic effect of presenilin 2 (PS2) overexpression is associated with down regulation of Bcl2 in cultured neurons. J. Neurochem., 79, 1161-1168 (2001).
    • (2001) J. Neurochem. , vol.79 , pp. 1161-1168
    • Araki, W.1    Yuasa, K.2    Takeda, S.3    Takeda, K.4    Shirotani, K.5    Takahashi, K.6    Tabira, T.7
  • 4
    • 0030580281 scopus 로고    scopus 로고
    • Alzheimer's associated presenilin2 confers increased sensitivity to apoptosis in PC12 cells
    • Deng, G., Pike, C. J., and Cotman, C. W., Alzheimer's associated presenilin2 confers increased sensitivity to apoptosis in PC12 cells. FEBS Lett., 397, 50-54 (1996).
    • (1996) FEBS Lett. , vol.397 , pp. 50-54
    • Deng, G.1    Pike, C.J.2    Cotman, C.W.3
  • 6
    • 1442348421 scopus 로고    scopus 로고
    • Alpha7-nicotinic acetylcholine receptors mediate an Abeta (1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones
    • Fodero, L. R., Mok, S. S., Losic, D., Martin, L. L., Aguilar, M. I., Barrow, C. J., Livett, B. G., and Small, D. H., Alpha7-nicotinic acetylcholine receptors mediate an Abeta (1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones. J. Neurochem., 88,1186-1193 (2004).
    • (2004) J. Neurochem. , vol.88 , pp. 1186-1193
    • Fodero, L.R.1    Mok, S.S.2    Losic, D.3    Martin, L.L.4    Aguilar, M.I.5    Barrow, C.J.6    Livett, B.G.7    Small, D.H.8
  • 7
    • 0037817311 scopus 로고    scopus 로고
    • Amyloid-beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation
    • Hu, W., Gray, N. W., and Brimijoin, S., Amyloid-beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation. J. Neurochem., 86, 470-478 (2003).
    • (2003) J. Neurochem. , vol.86 , pp. 470-478
    • Hu, W.1    Gray, N.W.2    Brimijoin, S.3
  • 9
    • 0029863697 scopus 로고    scopus 로고
    • Acetylcholinesterase accelerates assembly of amyloid beta peptides into Alzheimer's fibrils: Possible role of the periferal site of the enzyme
    • Inestrosa, N. C., Alvarez, A., Perez, C. A., Moreno, R. D., Vicente, M., Linker, C., Casaneuva, O. I., Soto, C., and Garrido, J., Acetylcholinesterase accelerates assembly of amyloid beta peptides into Alzheimer's fibrils: Possible role of the periferal site of the enzyme. Neuron, 16, 881-891 (1996).
    • (1996) Neuron , vol.16 , pp. 881-891
    • Inestrosa, N.C.1    Alvarez, A.2    Perez, C.A.3    Moreno, R.D.4    Vicente, M.5    Linker, C.6    Casaneuva, O.I.7    Soto, C.8    Garrido, J.9
  • 10
    • 0032984214 scopus 로고    scopus 로고
    • Presenilin overexpression arrests cells in the G1 phase of cell cycle. Arrest potentiated by the Alzheimer's disease PS2 (N141I) mutant
    • Janicki, S. M. and Monterio, M. J., Presenilin overexpression arrests cells in the G1 phase of cell cycle. Arrest potentiated by the Alzheimer's disease PS2 (N141I) mutant. Am. J. Pathol.,155, 135-144 (1999).
    • (1999) Am. J. Pathol. , vol.155 , pp. 135-144
    • Janicki, S.M.1    Monterio, M.J.2
  • 11
    • 0030771534 scopus 로고    scopus 로고
    • Increase apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin 2 mutation (N141I)
    • Janicki, S. and Montaeiro, M. J., Increase apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin 2 mutation (N141I). J. Cell Biol., 139, 485-495 (1997).
    • (1997) J. Cell Biol. , vol.139 , pp. 485-495
    • Janicki, S.1    Montaeiro, M.J.2
  • 13
    • 85039367292 scopus 로고    scopus 로고
    • PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release
    • in press
    • Lee, S. Y., Hwang D. Y., Kim, Y. K., Lee, J. W., Shin, I. C., Oh, K. W., Lee, M. K., Lim, J. S., Yoon, D. Y., Hwang, S. J., and Hong, J. T., PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release. FASEB J., in press (2005).
    • (2005) FASEB J.
    • Lee, S.Y.1    Hwang, D.Y.2    Kim, Y.K.3    Lee, J.W.4    Shin, I.C.5    Oh, K.W.6    Lee, M.K.7    Lim, J.S.8    Yoon, D.Y.9    Hwang, S.J.10    Hong, J.T.11
  • 14
    • 0036237097 scopus 로고    scopus 로고
    • Increase expression of intranuclear AChE involved in apoptosis of SK-N-SH cells
    • Lei, Y., Heng, Y. H., and Xue, J. Z., Increase expression of intranuclear AChE involved in apoptosis of SK-N-SH cells. Neurosci. Res., 42, 261-268 (2002).
    • (2002) Neurosci. Res. , vol.42 , pp. 261-268
    • Lei, Y.1    Heng, Y.H.2    Xue, J.Z.3
  • 15
    • 0033993523 scopus 로고    scopus 로고
    • Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression
    • Li, Y., Liu, L., Kang, J., Sheng, J. G., Barger, S. W., Mrak, R. E., and Griffin, W. S., Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression. J. Neurosci., 20,149-155 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 149-155
    • Li, Y.1    Liu, L.2    Kang, J.3    Sheng, J.G.4    Barger, S.W.5    Mrak, R.E.6    Griffin, W.S.7
  • 16
    • 0037219182 scopus 로고    scopus 로고
    • Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide
    • Melo, J. B., Agostinho, P., and Oliveira, C. R., Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide. Neurosci. Res., 45,117-127 (2003).
    • (2003) Neurosci. Res. , vol.45 , pp. 117-127
    • Melo, J.B.1    Agostinho, P.2    Oliveira, C.R.3
  • 18
    • 20044367140 scopus 로고    scopus 로고
    • Decrease in NF-kappaB, AP-1 and SP-1 activities in neuronal cells expressing presenilin 2
    • Nguyen, H. N., Lee, S. Y., Hwang, D. Y., Kim, Y. K., Yuk, D. Y., Lee, J. S., and Hong, J. T., Decrease in NF-kappaB, AP-1 and SP-1 activities in neuronal cells expressing presenilin 2. Neuroreport, 16, 731-735 (2005).
    • (2005) Neuroreport , vol.16 , pp. 731-735
    • Nguyen, H.N.1    Lee, S.Y.2    Hwang, D.Y.3    Kim, Y.K.4    Yuk, D.Y.5    Lee, J.S.6    Hong, J.T.7
  • 19
    • 0038618612 scopus 로고    scopus 로고
    • Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex
    • Rees, T., Hammond, P. I., Soreq, H., Younkin, S., and Brimijoin, S., Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex. Neurobiol. Aging, 24, 777-787 (2003).
    • (2003) Neurobiol. Aging , vol.24 , pp. 777-787
    • Rees, T.1    Hammond, P.I.2    Soreq, H.3    Younkin, S.4    Brimijoin, S.5
  • 20
    • 0038240721 scopus 로고    scopus 로고
    • Causative and susceptibility genes for Alzheimer's disease: A review
    • Rocchi, A., Pellegrini, S., Siciliano, G., and Murri, L., Causative and susceptibility genes for Alzheimer's disease: A review. Brain Res. Bull., 61, 1-24 (2003).
    • (2003) Brain Res. Bull. , vol.61 , pp. 1-24
    • Rocchi, A.1    Pellegrini, S.2    Siciliano, G.3    Murri, L.4
  • 21
    • 0037424301 scopus 로고    scopus 로고
    • Acetylcholinesterase is increased in mouse neuronal and astrocyte cultures after treatment with beta-amyloid peptides
    • Saez-Valero, J., Fodero, L. R., White, A. R., Barrow, C. J., Small, D. H., Acetylcholinesterase is increased in mouse neuronal and astrocyte cultures after treatment with beta-amyloid peptides. Brain Res., 965, 283-286 (2003).
    • (2003) Brain Res. , vol.965 , pp. 283-286
    • Saez-Valero, J.1    Fodero, L.R.2    White, A.R.3    Barrow, C.J.4    Small, D.H.5
  • 22
    • 1842375103 scopus 로고    scopus 로고
    • The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells
    • Sberna, G., Saez-Valero, J., Beyreuther, K., Masters, C. L., and Small, D. H., The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells. J. Neurochem., 69, 1177-1184 (1997).
    • (1997) J. Neurochem. , vol.69 , pp. 1177-1184
    • Sberna, G.1    Saez-Valero, J.2    Beyreuther, K.3    Masters, C.L.4    Small, D.H.5
  • 23
    • 3242782586 scopus 로고    scopus 로고
    • Brain cholinesterase: The molecular and cellular basis of Alzheimer's disease
    • Shen, Z. X., Brain cholinesterase: The molecular and cellular basis of Alzheimer's disease. Med. Hypotheses, 63, 308-321 (2004).
    • (2004) Med. Hypotheses , vol.63 , pp. 308-321
    • Shen, Z.X.1
  • 24
    • 4644333076 scopus 로고    scopus 로고
    • Protective role of Bcl-2 on beta-amyloid-induced cell death of differentiated PC12 cells: Reduction of NF-kappaB and p38 MAP kinase activation
    • Song, Y. S., Park, H. J., Kim, S. Y., Lee, S. H., Yoo, H. S., Lee, H. S., Lee, M. K., Oh, K. W., Kang, S. K., Lee, S. E., and Hong, J. T., Protective role of Bcl-2 on beta-amyloid-induced cell death of differentiated PC12 cells: Reduction of NF-kappaB and p38 MAP kinase activation. Neurosci. Res., 49, 69-80 (2004).
    • (2004) Neurosci. Res. , vol.49 , pp. 69-80
    • Song, Y.S.1    Park, H.J.2    Kim, S.Y.3    Lee, S.H.4    Yoo, H.S.5    Lee, H.S.6    Lee, M.K.7    Oh, K.W.8    Kang, S.K.9    Lee, S.E.10    Hong, J.T.11
  • 25
    • 85039385035 scopus 로고    scopus 로고
    • A unifying model for functional difference and redundancy of presenilin-1 and -2 in cell apoptosis and differentiation
    • 34257
    • Tamotsu, H. G., Atsushi, T., Yoshihisa, W., Naoyuki, I., Takashi, M., and Takeshi, T., A unifying model for functional difference and redundancy of presenilin-1 and -2 in cell apoptosis and differentiation. Gene, 34257, 1-9 (2003).
    • (2003) Gene , pp. 1-9
    • Tamotsu, H.G.1    Atsushi, T.2    Yoshihisa, W.3    Naoyuki, I.4    Takashi, M.5    Takeshi, T.6
  • 26
    • 0029671219 scopus 로고    scopus 로고
    • Interfering with apoptosis: Ca-binding protein ALG-2 and Alzheimer's disease gene ALG-3
    • Vito, P., Lacana, E., and D'Adamio, L., Interfering with apoptosis: Ca-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science, 271, 521-525 (1996).
    • (1996) Science , vol.271 , pp. 521-525
    • Vito, P.1    Lacana, E.2    D'Adamio, L.3
  • 27
    • 0029856850 scopus 로고    scopus 로고
    • Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3
    • Vito, P., Wolozin, B., Ganjei, J. K., Iwasaki, K., Lacana, E., and D'Adamio, L., Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. J. Biol. Chem., 271, 31025-31028 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 31025-31028
    • Vito, P.1    Wolozin, B.2    Ganjei, J.K.3    Iwasaki, K.4    Lacana, E.5    D'Adamio, L.6
  • 28
    • 0036237097 scopus 로고    scopus 로고
    • Increased expression of intranuclear AChE involved in apoptosis of SK-N-SH cells
    • Yang, L., He, H. Y., Zhang, X. J., Increased expression of intranuclear AChE involved in apoptosis of SK-N-SH cells. Neurosci. Res., 42, 261-268 (2002).
    • (2002) Neurosci. Res. , vol.42 , pp. 261-268
    • Yang, L.1    He, H.Y.2    Zhang, X.J.3
  • 29
    • 0041817715 scopus 로고    scopus 로고
    • Apoptosis induced by beta-amyloid 25-35 in acetylcholinesterase- overexpressing neuroblastoma cells
    • Zhang, H. Y., Brimijoin, S., and Tang, X. C., Apoptosis induced by beta-amyloid 25-35 in acetylcholinesterase-overexpressing neuroblastoma cells. Acta Pharmacol. Sin., 24, 853-858 (2003).
    • (2003) Acta Pharmacol. Sin. , vol.24 , pp. 853-858
    • Zhang, H.Y.1    Brimijoin, S.2    Tang, X.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.