-
1
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj, M., Wicha, M. S., Benito-Hernandez, A., Morrison, S. J., and Clarke, M. F. (2003). Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. U.S.A. 100, 3983-3988.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
2
-
-
76249128304
-
Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity
-
Aymeric, L., Apetoh, L., Ghiringhelli, F., Tesniere, A., Martins, I., Kroemer, G., Smyth, M. J., and Zitvogel, L. (2010). Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity. Cancer Res. 70, 855-858.
-
(2010)
Cancer Res.
, vol.70
, pp. 855-858
-
-
Aymeric, L.1
Apetoh, L.2
Ghiringhelli, F.3
Tesniere, A.4
Martins, I.5
Kroemer, G.6
Smyth, M.J.7
Zitvogel, L.8
-
3
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao, S., Wu, Q., McLendon, R. E., Hao, Y., Shi, Q., Hjelmeland, A. B., Dewhirst, M. W., Bigner, D. D., and Rich, J. N. (2006a). Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
4
-
-
33748051406
-
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
-
Bao, S., Wu, Q., Sathornsumetee, S., Hao, Y., Li, Z., Hjelmeland, A. B., Shi, Q., McLendon, R. E., Bigner, D. D., and Rich, J. N. (2006b). Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res. 66, 7843-7848.
-
(2006)
Cancer Res.
, vol.66
, pp. 7843-7848
-
-
Bao, S.1
Wu, Q.2
Sathornsumetee, S.3
Hao, Y.4
Li, Z.5
Hjelmeland, A.B.6
Shi, Q.7
McLendon, R.E.8
Bigner, D.D.9
Rich, J.N.10
-
5
-
-
34247595838
-
Modeling the initiation and progression of human acute leukemia in mice
-
Barabe, F., Kennedy, J. A., Hope, K. J., and Dick, J. E. (2007). Modeling the initiation and progression of human acute leukemia in mice. Science 316, 600-604.
-
(2007)
Science
, vol.316
, pp. 600-604
-
-
Barabe, F.1
Kennedy, J.A.2
Hope, K.J.3
Dick, J.E.4
-
6
-
-
34548580317
-
Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells
-
Beckers, A., Organe, S., Timmermans, L., Scheys, K., Peeters, A., Brusselmans, K., Verhoeven, G., and Swinnen, J. V. (2007). Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells. Cancer Res. 67, 8180-8187.
-
(2007)
Cancer Res.
, vol.67
, pp. 8180-8187
-
-
Beckers, A.1
Organe, S.2
Timmermans, L.3
Scheys, K.4
Peeters, A.5
Brusselmans, K.6
Verhoeven, G.7
Swinnen, J.V.8
-
7
-
-
33846002728
-
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
Bonnet, S., Archer, S. L., Allalunis-Turner, J., Haromy, A., Beaulieu, C., Thompson, R., Lee, C. T., Lopaschuk, G. D., Puttagunta, L., Harry, G., Hashimoto, K., Porter, C. J., Andrade, M. A., Thebaud, B., and Michelakis, E. D. (2007). A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell 11, 37-51.
-
(2007)
Cancer Cell
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Allalunis-Turner, J.3
Haromy, A.4
Beaulieu, C.5
Thompson, R.6
Lee, C.T.7
Lopaschuk, G.D.8
Puttagunta, L.9
Harry, G.10
Hashimoto, K.11
Porter, C.J.12
Andrade, M.A.13
Thebaud, B.14
Michelakis, E.D.15
-
8
-
-
33748175037
-
Concurrent chemoradiotherapy for locally advanced, nonmetastatic, squamous carcinoma of the head and neck: consensus, controversy, and conundrum
-
Brizel, D. M., and Esclamado, R. (2006). Concurrent chemoradiotherapy for locally advanced, nonmetastatic, squamous carcinoma of the head and neck: consensus, controversy, and conundrum. J. Clin. Oncol. 24, 2612-2617.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 2612-2617
-
-
Brizel, D.M.1
Esclamado, R.2
-
9
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese, C., Poppleton, H., Kocak, M., Hogg, T. L., Fuller, C., Hamner, B., Oh, E. Y., Gaber, M. W., Finklestein, D., Allen, M., Frank, A., Bayazitov, I. T., Zakharenko, S. S., Gajjar, A., Davidoff, A., and Gilbertson, R. J. (2007). A perivascular niche for brain tumor stem cells. Cancer Cell 11, 69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
Oh, E.Y.7
Gaber, M.W.8
Finklestein, D.9
Allen, M.10
Frank, A.11
Bayazitov, I.T.12
Zakharenko, S.S.13
Gajjar, A.14
Davidoff, A.15
Gilbertson, R.J.16
-
10
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., Rassenti, L., Kipps, T., Negrini, M., Bullrich, F., and Croce, C. M. (2002). Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 99, 15524-15529.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
Noch, E.6
Aldler, H.7
Rattan, S.8
Keating, M.9
Rai, K.10
Rassenti, L.11
Kipps, T.12
Negrini, M.13
Bullrich, F.14
Croce, C.M.15
-
11
-
-
0033614962
-
Essential role for oncogenic Ras in tumour maintenance
-
Chin, L., Tam, A., Pomerantz, J., Wong, M., Holash, J., Bardeesy, N., Shen, Q., O'Hagan, R., Pantginis, J., Zhou, H., Horner, J. W. II, Cordon-Cardo, C., Yancopoulos, G. D., and DePinho, R. A. (1999). Essential role for oncogenic Ras in tumour maintenance. Nature 400, 468-472.
-
(1999)
Nature
, vol.400
, pp. 468-472
-
-
Chin, L.1
Tam, A.2
Pomerantz, J.3
Wong, M.4
Holash, J.5
Bardeesy, N.6
Shen, Q.7
O'Hagan, R.8
Pantginis, J.9
Zhou, H.10
Horner II, J.W.11
Cordon-Cardo, C.12
Yancopoulos, G.D.13
DePinho, R.A.14
-
12
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho, Y. S., Challa, S., Moquin, D., Genga, R., Ray, T. D., Guildford, M., and Chan, F. K. (2009). Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137, 1112-1123.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.7
-
13
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino, A., Calin, G. A., Fabbri, M., Iorio, M. V., Ferracin, M., Shimizu, M., Wojcik, S. E., Aqeilan, R. I., Zupo, S., Dono, M., Rassenti, L., Alder, H., Volinia, S., Liu, C. G., Kipps, T. J., Negrini, M., and Croce, C. M. (2005). miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. U.S.A. 102, 13944-13949.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
Iorio, M.V.4
Ferracin, M.5
Shimizu, M.6
Wojcik, S.E.7
Aqeilan, R.I.8
Zupo, S.9
Dono, M.10
Rassenti, L.11
Alder, H.12
Volinia, S.13
Liu, C.G.14
Kipps, T.J.15
Negrini, M.16
Croce, C.M.17
-
14
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
Croce, C. M. (2009). Causes and consequences of microRNA dysregulation in cancer. Nat. Rev. Genet. 10, 704-714.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 704-714
-
-
Croce, C.M.1
-
15
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev, A., Hitomi, J., Germscheid, M., Ch'en, I. L., Korkina, O., Teng, X., Abbott, D., Cuny, G. D., Yuan, C., Wagner, G., Hedrick, S. M., Gerber, S. A., Lugovskoy, A., and Yuan, J. (2008). Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat. Chem. Biol. 4, 313-321.
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
Hedrick, S.M.11
Gerber, S.A.12
Lugovskoy, A.13
Yuan, J.14
-
16
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev, A., Huang, Z., Boyce, M., Li, Y., Jagtap, P., Mizushima, N., Cuny, G. D., Mitchison, T. J., Moskowitz, M. A., and Yuan, J. (2005). Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat. Chem. Biol. 1, 112-119.
-
(2005)
Nat. Chem. Biol.
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
Cuny, G.D.7
Mitchison, T.J.8
Moskowitz, M.A.9
Yuan, J.10
-
17
-
-
0033180211
-
Reversible tumorigenesis by MYC in hematopoietic lineages
-
Felsher, D. W., and Bishop, J. M. (1999). Reversible tumorigenesis by MYC in hematopoietic lineages. Mol. Cell 4, 199-207.
-
(1999)
Mol. Cell
, vol.4
, pp. 199-207
-
-
Felsher, D.W.1
Bishop, J.M.2
-
18
-
-
34250753161
-
Cell death modalities: classification and pathophysiological implications
-
Galluzzi, L., Maiuri, M. C., Vitale, I., Zischka, H., Castedo, M., Zitvogel, L., and Kroemer, G. (2007). Cell death modalities: classification and pathophysiological implications. Cell Death Differ. 14, 1237-1243.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1237-1243
-
-
Galluzzi, L.1
Maiuri, M.C.2
Vitale, I.3
Zischka, H.4
Castedo, M.5
Zitvogel, L.6
Kroemer, G.7
-
19
-
-
67650588646
-
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
-
Garzon, R., Liu, S., Fabbri, M., Liu, Z., Heaphy, C. E., Callegari, E., Schwind, S., Pang, J., Yu, J., Muthusamy, N., Havelange, V., Volinia, S., Blum, W., Rush, L. J., Perrotti, D., Andreeff, M., Bloomfield, C. D., Byrd, J. C., Chan, K., Wu, L. C., Croce, C. M., and Marcucci, G. (2009). MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 113, 6411-6418.
-
(2009)
Blood
, vol.113
, pp. 6411-6418
-
-
Garzon, R.1
Liu, S.2
Fabbri, M.3
Liu, Z.4
Heaphy, C.E.5
Callegari, E.6
Schwind, S.7
Pang, J.8
Yu, J.9
Muthusamy, N.10
Havelange, V.11
Volinia, S.12
Blum, W.13
Rush, L.J.14
Perrotti, D.15
Andreeff, M.16
Bloomfield, C.D.17
Byrd, J.C.18
Chan, K.19
Wu, L.C.20
Croce, C.M.21
Marcucci, G.22
more..
-
20
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
Ghiringhelli, F., Apetoh, L., Tesniere, A., Aymeric, L., Ma, Y., Ortiz, C., Vermaelen, K., Panaretakis, T., Mignot, G., Ullrich, E., Perfettini, J. L., Schlemmer, F., Tasdemir, E., Uhl, M., Génin, P., Civas, A., Ryffel, B., Kanellopoulos, J., Tschopp, J., André, F., Lidereau, R., McLaughlin, N. M., Haynes, N. M., Smyth, M. J., Kroemer, G., and Zitvogel, L. (2009). Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat. Med. 15, 1170-1178.
-
(2009)
Nat. Med.
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
Aymeric, L.4
Ma, Y.5
Ortiz, C.6
Vermaelen, K.7
Panaretakis, T.8
Mignot, G.9
Ullrich, E.10
Perfettini, J.L.11
Schlemmer, F.12
Tasdemir, E.13
Uhl, M.14
Génin, P.15
Civas, A.16
Ryffel, B.17
Kanellopoulos, J.18
Tschopp, J.19
André, F.20
Lidereau, R.21
McLaughlin, N.M.22
Haynes, N.M.23
Smyth, M.J.24
Kroemer, G.25
Zitvogel, L.26
more..
-
21
-
-
33846018602
-
Cell death by necrosis: towards a molecular definition
-
Golstein, P., and Kroemer, G. (2007). Cell death by necrosis: towards a molecular definition. Trends Biochem. Sci. 32, 37-43.
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 37-43
-
-
Golstein, P.1
Kroemer, G.2
-
22
-
-
28544446058
-
Mitochondrial tumour suppressors: a genetic and biochemical update
-
Gottlieb, E., and Tomlinson, I. P. (2005). Mitochondrial tumour suppressors: a genetic and biochemical update. Nat. Rev. Cancer 5, 857-866.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 857-866
-
-
Gottlieb, E.1
Tomlinson, I.P.2
-
23
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman, C., Stephens, P., Smith, R., Dalgliesh, G. L., Hunter, C., Bignell, G., Davies, H., Teague, J., Butler, A., Stevens, C., Edkins, S., O'Meara, S., Vastrik, I., Schmidt, E. E., Avis, T., Barthorpe, S., Bhamra, G., Buck, G., Choudhury, B., Clements, J., Cole, J., Dicks, E., Forbes, S., Gray, K., Halliday, K., Harrison, R., Hills, K., Hinton, J., Jenkinson, A., Jones, D., Menzies, A., Mironenko, T., Perry, J., Raine, K., Richardson, D., Shepherd, R., Small, A., Tofts, C., Varian, J., Webb, T., West, S., Widaa, S., Yates, A., Cahill, D. P., Louis, D. N., Goldstraw, P., Nicholson, A. G., Brasseur, F., Looijenga, L., Weber, B. L., Chiew, Y. E., DeFazio, A., Greaves, M. F., Green, A. R., Campbell, P., Birney, E., Easton, D. F., Chenevix-Trench, G., Tan, M. H., Khoo, S. K., Teh, B. T., Yuen, S. T., Leung, S. Y., Wooster, R., Futreal, P. A., and Stratton, M. R. (2007). Patterns of somatic mutation in human cancer genomes. Nature 446, 153-158.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
Bignell, G.6
Davies, H.7
Teague, J.8
Butler, A.9
Stevens, C.10
Edkins, S.11
O'Meara, S.12
Vastrik, I.13
Schmidt, E.E.14
Avis, T.15
Barthorpe, S.16
Bhamra, G.17
Buck, G.18
Choudhury, B.19
Clements, J.20
Cole, J.21
Dicks, E.22
Forbes, S.23
Gray, K.24
Halliday, K.25
Harrison, R.26
Hills, K.27
Hinton, J.28
Jenkinson, A.29
Jones, D.30
Menzies, A.31
Mironenko, T.32
Perry, J.33
Raine, K.34
Richardson, D.35
Shepherd, R.36
Small, A.37
Tofts, C.38
Varian, J.39
Webb, T.40
West, S.41
Widaa, S.42
Yates, A.43
Cahill, D.P.44
Louis, D.N.45
Goldstraw, P.46
Nicholson, A.G.47
Brasseur, F.48
Looijenga, L.49
Weber, B.L.50
Chiew, Y.E.51
DeFazio, A.52
Greaves, M.F.53
Green, A.R.54
Campbell, P.55
Birney, E.56
Easton, D.F.57
Chenevix-Trench, G.58
Tan, M.H.59
Khoo, S.K.60
Teh, B.T.61
Yuen, S.T.62
Leung, S.Y.63
Wooster, R.64
Futreal, P.A.65
Stratton, M.R.66
more..
-
24
-
-
16844363378
-
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
-
Guzman, M. L., Rossi, R. M., Karnischky, L., Li, X., Peterson, D. R., Howard, D. S., and Jordan, C. T. (2005). The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 105, 4163-4169.
-
(2005)
Blood
, vol.105
, pp. 4163-4169
-
-
Guzman, M.L.1
Rossi, R.M.2
Karnischky, L.3
Li, X.4
Peterson, D.R.5
Howard, D.S.6
Jordan, C.T.7
-
25
-
-
0036561908
-
Modelling the molecular circuitry of cancer
-
Hahn, W. C., and Weinberg, R. A. (2002). Modelling the molecular circuitry of cancer. Nat. Rev. Cancer 2, 331-341.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 331-341
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
26
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., and Weinberg, R. A. (2000). The hallmarks of cancer. Cell 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
27
-
-
26644441651
-
ATP citrate lyase inhibition can suppress tumor cell growth
-
Hatzivassiliou, G., Zhao, F., Bauer, D. E., Andreadis, C., Shaw, A. N., Dhanak, D., Hingorani, S. R., Tuveson, D. A., and Thompson, C. B. (2005). ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell 8, 311-321.
-
(2005)
Cancer Cell
, vol.8
, pp. 311-321
-
-
Hatzivassiliou, G.1
Zhao, F.2
Bauer, D.E.3
Andreadis, C.4
Shaw, A.N.5
Dhanak, D.6
Hingorani, S.R.7
Tuveson, D.A.8
Thompson, C.B.9
-
28
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He, S., Wang, L., Miao, L., Wang, T., Du, F., Zhao, L., and Wang, X. (2009). Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 137, 1100-1111.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
Wang, X.7
-
29
-
-
0020688933
-
Tumor heterogeneity: biological implications and therapeutic consequences
-
Heppner, G. H., and Miller, B. E. (1983). Tumor heterogeneity: biological implications and therapeutic consequences. Cancer Metastasis Rev. 2, 5-23.
-
(1983)
Cancer Metastasis Rev.
, vol.2
, pp. 5-23
-
-
Heppner, G.H.1
Miller, B.E.2
-
30
-
-
0000537744
-
Studies of the dissemination and quantitative transplantation of a lymphocytic leukaemia of CBA mice
-
Hewitt, H. B. (1958). Studies of the dissemination and quantitative transplantation of a lymphocytic leukaemia of CBA mice. Br. J. Cancer 12, 378-401.
-
(1958)
Br. J. Cancer
, vol.12
, pp. 378-401
-
-
Hewitt, H.B.1
-
31
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi, J., Christofferson, D. E., Ng, A., Yao, J., Degterev, A., Xavier, R. J., and Yuan, J. (2008). Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 135, 1311-1323.
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
Yuan, J.7
-
32
-
-
0033987718
-
Reversibility of acute B-cell leukaemia induced by BCR-ABL1
-
Huettner, C. S., Zhang, P., Van Etten, R. A., and Tenen, D. G. (2000). Reversibility of acute B-cell leukaemia induced by BCR-ABL1. Nat. Genet. 24, 57-60.
-
(2000)
Nat. Genet.
, vol.24
, pp. 57-60
-
-
Huettner, C.S.1
Zhang, P.2
Van Etten, R.A.3
Tenen, D.G.4
-
33
-
-
35948984135
-
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
-
Ishikawa, F., Yoshida, S., Saito, Y., Hijikata, A., Kitamura, H., Tanaka, S., Nakamura, R., Tanaka, T., Tomiyama, H., Saito, N., Fukata, M., Miyamoto, T., Lyons, B., Ohshima, K., Uchida, N., Taniguchi, S., Ohara, O., Akashi, K., Harada, M., and Shultz, L. D. (2007). Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region. Nat. Biotechnol. 25, 1315-1321.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 1315-1321
-
-
Ishikawa, F.1
Yoshida, S.2
Saito, Y.3
Hijikata, A.4
Kitamura, H.5
Tanaka, S.6
Nakamura, R.7
Tanaka, T.8
Tomiyama, H.9
Saito, N.10
Fukata, M.11
Miyamoto, T.12
Lyons, B.13
Ohshima, K.14
Uchida, N.15
Taniguchi, S.16
Ohara, O.17
Akashi, K.18
Harada, M.19
Shultz, L.D.20
more..
-
34
-
-
0037025201
-
Sustained loss of a neoplastic phenotype by brief inactivation of MYC
-
Jain, M., Arvanitis, C., Chu, K., Dewey, W., Leonhardt, E., Trinh, M., Sundberg, C. D., Bishop, J. M., and Felsher, D. W. (2002). Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science 297, 102-104.
-
(2002)
Science
, vol.297
, pp. 102-104
-
-
Jain, M.1
Arvanitis, C.2
Chu, K.3
Dewey, W.4
Leonhardt, E.5
Trinh, M.6
Sundberg, C.D.7
Bishop, J.M.8
Felsher, D.W.9
-
35
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
Jin, L., Hope, K. J., Zhai, Q., Smadja-Joffe, F., and Dick, J. E. (2006). Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat. Med. 12, 1167-1174.
-
(2006)
Nat. Med.
, vol.12
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
36
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson, S. M., Grosshans, H., Shingara, J., Byrom, M., Jarvis, R., Cheng, A., Labourier, E., Reinert, K. L., Brown, D., and Slack, F. J. (2005). RAS is regulated by the let-7 microRNA family. Cell 120, 635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
Labourier, E.7
Reinert, K.L.8
Brown, D.9
Slack, F.J.10
-
37
-
-
36849010167
-
Adaptive immunity maintains occult cancer in an equilibrium state
-
Koebel, C. M., Vermi, W., Swann, J. B., Zerafa, N., Rodig, S. J., Old, L. J., Smyth, M. J., and Schreiber, R. D. (2007). Adaptive immunity maintains occult cancer in an equilibrium state. Nature 450, 903-907.
-
(2007)
Nature
, vol.450
, pp. 903-907
-
-
Koebel, C.M.1
Vermi, W.2
Swann, J.B.3
Zerafa, N.4
Rodig, S.J.5
Old, L.J.6
Smyth, M.J.7
Schreiber, R.D.8
-
38
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota, J., Chivukula, R. R., O'Donnell, K. A., Wentzel, E. A., Montgomery, C. L., Hwang, H. W., Chang, T. C., Vivekanandan, P., Torbenson, M., Clark, K. R., Mendell, J. R., and Mendell, J. T. (2009). Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137, 1005-1017.
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
Wentzel, E.A.4
Montgomery, C.L.5
Hwang, H.W.6
Chang, T.C.7
Vivekanandan, P.8
Torbenson, M.9
Clark, K.R.10
Mendell, J.R.11
Mendell, J.T.12
-
39
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer, G., Galluzzi, L., and Brenner, C. (2007). Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87, 99-163.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
40
-
-
57649149333
-
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
-
Nomenclature Committee on Cell Death 2009.
-
Kroemer, G., Galluzzi, L., Vandenabeele, P., Abrams, J., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., El-Deiry, W. S., Golstein, P., Green, D. R., Hengartner, M., Knight, R. A., Kumar, S., Lipton, S. A., Malorni, W., Nuñez, G., Peter, M. E, Tschopp, J., Yuan, J., Piacentini, M., Zhivotovsky, B., Melino, G.; Nomenclature Committee on Cell Death 2009. (2009). Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ. 16, 3-11.
-
(2009)
Cell Death Differ.
, vol.16
, pp. 3-11
-
-
Kroemer, G.1
Galluzzi, L.2
Vandenabeele, P.3
Abrams, J.4
Alnemri, E.S.5
Baehrecke, E.H.6
Blagosklonny, M.V.7
El-Deiry, W.S.8
Golstein, P.9
Green, D.R.10
Hengartner, M.11
Knight, R.A.12
Kumar, S.13
Lipton, S.A.14
Malorni, W.15
Nuñez, G.16
Peter M.E Tschopp, J.17
Yuan, J.18
Piacentini, M.19
Zhivotovsky, B.20
Melino, G.21
more..
-
41
-
-
44449147036
-
Tumor cell metabolism: cancer's Achilles' heel
-
Kroemer, G., and Pouyssegur, J. (2008). Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 13, 472-482.
-
(2008)
Cancer Cell
, vol.13
, pp. 472-482
-
-
Kroemer, G.1
Pouyssegur, J.2
-
42
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot, T., Sirard, C., Vormoor, J., Murdoch, B., Hoang, T., Caceres-Cortes, J., Minden, M., Paterson, B., Caligiuri, M. A., and Dick, J. E. (1994). A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367, 645-648.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
43
-
-
0023697978
-
Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis
-
Laster, S. M., Wood, J. G., and Gooding, L. R. (1988). Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J. Immunol. 141, 2629-2634.
-
(1988)
J. Immunol.
, vol.141
, pp. 2629-2634
-
-
Laster, S.M.1
Wood, J.G.2
Gooding, L.R.3
-
44
-
-
78049496814
-
mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion
-
Lee, J. Y., Nakada, D., Yilmaz, O. H., Tothova, Z., Joseph, N. M., Lim, M. S., Gilliland, D. G., and Morrison, S. J. (2010). mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion. Cell Stem Cell 7, 593-605.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 593-605
-
-
Lee, J.Y.1
Nakada, D.2
Yilmaz, O.H.3
Tothova, Z.4
Joseph, N.M.5
Lim, M.S.6
Gilliland, D.G.7
Morrison, S.J.8
-
45
-
-
36849056027
-
The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore
-
Lim, S. Y., Davidson, S. M., Mocanu, M. M., Yellon, D. M., and Smith, C. C. (2007). The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore. Cardiovasc. Drugs Ther. 21, 467-469.
-
(2007)
Cardiovasc. Drugs Ther.
, vol.21
, pp. 467-469
-
-
Lim, S.Y.1
Davidson, S.M.2
Mocanu, M.M.3
Yellon, D.M.4
Smith, C.C.5
-
46
-
-
61449182121
-
Principles of cancer therapy: oncogene and non-oncogene addiction
-
Luo, J., Solimini, N. L., and Elledge, S. J. (2009). Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 136, 823-837.
-
(2009)
Cell
, vol.136
, pp. 823-837
-
-
Luo, J.1
Solimini, N.L.2
Elledge, S.J.3
-
47
-
-
34247553146
-
Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells
-
MacKenzie, E. D., Selak, M. A., Tennant, D. A., Payne, L. J., Crosby, S., Frederiksen, C. M., Watson, D. G., and Gottlieb, E. (2007). Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells. Mol. Cell. Biol. 27, 3282-3289.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3282-3289
-
-
MacKenzie, E.D.1
Selak, M.A.2
Tennant, D.A.3
Payne, L.J.4
Crosby, S.5
Frederiksen, C.M.6
Watson, D.G.7
Gottlieb, E.8
-
48
-
-
78049514583
-
Surface-exposed calreticulin in the interaction between dying cells and phagocytes
-
Martins, I., Kepp, O., Galluzzi, L., Senovilla, L., Schlemmer, F., Adjemian, S., Menger, L., Michaud, M., Zitvogel, L., and Kroemer, G. (2010). Surface-exposed calreticulin in the interaction between dying cells and phagocytes. Ann. N. Y. Acad. Sci. 1209, 77-82.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1209
, pp. 77-82
-
-
Martins, I.1
Kepp, O.2
Galluzzi, L.3
Senovilla, L.4
Schlemmer, F.5
Adjemian, S.6
Menger, L.7
Michaud, M.8
Zitvogel, L.9
Kroemer, G.10
-
49
-
-
41949102707
-
miRiad roles for the miR-17-92 cluster in development and disease
-
Mendell, J. T. (2008). miRiad roles for the miR-17-92 cluster in development and disease. Cell 133, 217-222.
-
(2008)
Cell
, vol.133
, pp. 217-222
-
-
Mendell, J.T.1
-
50
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
Meng, F., Henson, R., Wehbe-Janek, H., Ghoshal, K., Jacob, S. T., and Patel, T. (2007). MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133, 647-658.
-
(2007)
Gastroenterology
, vol.133
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
51
-
-
69349087479
-
Anti-and pro-tumor functions of autophagy
-
Morselli, E., Galluzzi, L., Kepp, O., Vicencio, J. M., Criollo, A., Maiuri, M. C., and Kroemer, G. (2009). Anti-and pro-tumor functions of autophagy. Biochim. Biophys. Acta 1793, 1524-1532.
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 1524-1532
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
Vicencio, J.M.4
Criollo, A.5
Maiuri, M.C.6
Kroemer, G.7
-
52
-
-
78650911946
-
Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI
-
Northington, F. J., Chavez-Valdez, R., Graham, E. M., Razdan, S., Gauda, E. B., and Martin, L. J. (2011). Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI. J. Cereb. Blood Flow Metab. 31, 178-189.
-
(2011)
J. Cereb. Blood Flow Metab.
, vol.31
, pp. 178-189
-
-
Northington, F.J.1
Chavez-Valdez, R.2
Graham, E.M.3
Razdan, S.4
Gauda, E.B.5
Martin, L.J.6
-
53
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell, P. C. (1976). The clonal evolution of tumor cell populations. Science 194, 23-28.
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
54
-
-
33846057130
-
Calreticulin exposure dictates the immunogenicity of cancer cell death
-
Obeid, M., Tesniere, A., Ghiringhelli, F., Fimia, G. M., Apetoh, L., Perfettini, J. L., Castedo, M., Mignot, G., Panaretakis, T., Casares, N., Métivier, D., Larochette, N., van Endert, P., Ciccosanti, F., Piacentini, M., Zitvogel, L., and Kroemer, G. (2007). Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat. Med. 13, 54-61.
-
(2007)
Nat. Med.
, vol.13
, pp. 54-61
-
-
Obeid, M.1
Tesniere, A.2
Ghiringhelli, F.3
Fimia, G.M.4
Apetoh, L.5
Perfettini, J.L.6
Castedo, M.7
Mignot, G.8
Panaretakis, T.9
Casares, N.10
Métivier, D.11
Larochette, N.12
van Endert, P.13
Ciccosanti, F.14
Piacentini, M.15
Zitvogel, L.16
Kroemer, G.17
-
55
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell, K. A., Wentzel, E. A., Zeller, K. I., Dang, C. V., and Mendell, J. T. (2005). c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435, 839-843.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
56
-
-
49949115791
-
The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death
-
Panaretakis, T., Joza, N., Modjtahedi, N., Tesniere, A., Vitale, I., Durchschlag, M., Fimia, G. M., Kepp, O., Piacentini, M., Froehlich, K. U., van Endert, P., Zitvogel, L., Madeo, F., and Kroemer, G. (2008). The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death. Cell Death Differ. 15, 1499-1509.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 1499-1509
-
-
Panaretakis, T.1
Joza, N.2
Modjtahedi, N.3
Tesniere, A.4
Vitale, I.5
Durchschlag, M.6
Fimia, G.M.7
Kepp, O.8
Piacentini, M.9
Froehlich, K.U.10
van Endert, P.11
Zitvogel, L.12
Madeo, F.13
Kroemer, G.14
-
57
-
-
0033001621
-
Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion
-
Pelengaris, S., Littlewood, T., Khan, M., Elia, G., and Evan, G. (1999). Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Mol. Cell 3, 565-577.
-
(1999)
Mol. Cell
, vol.3
, pp. 565-577
-
-
Pelengaris, S.1
Littlewood, T.2
Khan, M.3
Elia, G.4
Evan, G.5
-
58
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
-
Piccirillo, S. G., Reynolds, B. A., Zanetti, N., Lamorte, G., Binda, E., Broggi, G., Brem, H., Olivi, A., Dimeco, F., and Vescovi, A. L. (2006). Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature 444, 761-765.
-
(2006)
Nature
, vol.444
, pp. 761-765
-
-
Piccirillo, S.G.1
Reynolds, B.A.2
Zanetti, N.3
Lamorte, G.4
Binda, E.5
Broggi, G.6
Brem, H.7
Olivi, A.8
Dimeco, F.9
Vescovi, A.L.10
-
59
-
-
26444570010
-
Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations
-
Pollard, P. J., Briere, J. J., Alam, N. A., Barwell, J., Barclay, E., Wortham, N. C., Hunt, T., Mitchell, M., Olpin, S., Moat, S. J., Hargreaves, I. P., Heales, S. J., Chung, Y. L., Griffiths, J. R., Dalgleish, A., McGrath, J. A., Gleeson, M. J., Hodgson, S. V., Poulsom, R., Rustin, P., and Tomlinson, I. P. (2005). Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum. Mol. Genet. 14, 2231-2239.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 2231-2239
-
-
Pollard, P.J.1
Briere, J.J.2
Alam, N.A.3
Barwell, J.4
Barclay, E.5
Wortham, N.C.6
Hunt, T.7
Mitchell, M.8
Olpin, S.9
Moat, S.J.10
Hargreaves, I.P.11
Heales, S.J.12
Chung, Y.L.13
Griffiths, J.R.14
Dalgleish, A.15
McGrath, J.A.16
Gleeson, M.J.17
Hodgson, S.V.18
Poulsom, R.19
Rustin, P.20
Tomlinson, I.P.21
more..
-
60
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur, J., Dayan, F., and Mazure, N. M. (2006). Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441, 437-443.
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
61
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya, T., Morrison, S. J., Clarke, M. F., and Weissman, I. L. (2001). Stem cells, cancer, and cancer stem cells. Nature 414, 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
62
-
-
77952918274
-
Genetic variation in microRNA networks: the implications for cancer research
-
Ryan, B. M., Robles, A. I., and Harris, C. C. (2010). Genetic variation in microRNA networks: the implications for cancer research. Nat. Rev. Cancer 10, 389-402.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 389-402
-
-
Ryan, B.M.1
Robles, A.I.2
Harris, C.C.3
-
63
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
Saito, Y., Liang, G., Egger, G., Friedman, J. M., Chuang, J. C., Coetzee, G. A., and Jones, P. A. (2006). Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9, 435-443.
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
Jones, P.A.7
-
64
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
-
Selak, M. A., Armour, S. M., MacKenzie, E. D., Boulahbel, H., Watson, D. G., Mansfield, K. D., Pan, Y., Simon, M. C., Thompson, C. B., and Gottlieb, E. (2005). Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 7, 77-85.
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
65
-
-
0027905014
-
Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
-
Shirasawa, S., Furuse, M., Yokoyama, N., and Sasazuki, T. (1993). Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science 260, 85-88.
-
(1993)
Science
, vol.260
, pp. 85-88
-
-
Shirasawa, S.1
Furuse, M.2
Yokoyama, N.3
Sasazuki, T.4
-
66
-
-
35449002129
-
Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging
-
Simons, A. L., Fath, M. A., Mattson, D. M., Smith, B. J., Walsh, S. A., Graham, M. M., Hichwa, R. D., Buatti, J. M., Dornfeld, K., and Spitz, D. R. (2007). Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging. Int. J. Radiat. Oncol. Biol. Phys. 69, 1222-1230.
-
(2007)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.69
, pp. 1222-1230
-
-
Simons, A.L.1
Fath, M.A.2
Mattson, D.M.3
Smith, B.J.4
Walsh, S.A.5
Graham, M.M.6
Hichwa, R.D.7
Buatti, J.M.8
Dornfeld, K.9
Spitz, D.R.10
-
67
-
-
33646755569
-
Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity
-
Smyth, M. J., Dunn, G. P., and Schreiber, R. D. (2006). Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv. Immunol. 90, 1-50.
-
(2006)
Adv. Immunol.
, vol.90
, pp. 1-50
-
-
Smyth, M.J.1
Dunn, G.P.2
Schreiber, R.D.3
-
68
-
-
34548785473
-
Non-oncogene addiction and the stress phenotype of cancer cells
-
Solimini, N. L., Luo, J., and Elledge, S. J. (2007). Non-oncogene addiction and the stress phenotype of cancer cells. Cell 130, 986-988.
-
(2007)
Cell
, vol.130
, pp. 986-988
-
-
Solimini, N.L.1
Luo, J.2
Elledge, S.J.3
-
69
-
-
78650718758
-
Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
-
doi: 10.1073/pnas.1009179107
-
Trichonas, G., Murakami, Y., Thanos, A., Morizane, Y., Kayama, M., Debouck, C. M., Hisatomi, T., Miller, J. W., and Vavvas, D. G. (2011). Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.1009179107
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
-
-
Trichonas, G.1
Murakami, Y.2
Thanos, A.3
Morizane, Y.4
Kayama, M.5
Debouck, C.M.6
Hisatomi, T.7
Miller, J.W.8
Vavvas, D.G.9
-
70
-
-
77954593965
-
Virus inhibition of RIP3-dependent necrosis
-
Upton, J. W., Kaiser, W. J., and Mocarski, E. S. (2010). Virus inhibition of RIP3-dependent necrosis. Cell Host Microbe 7, 302-313.
-
(2010)
Cell Host Microbe
, vol.7
, pp. 302-313
-
-
Upton, J.W.1
Kaiser, W.J.2
Mocarski, E.S.3
-
71
-
-
77957105977
-
Molecular mechanisms of necroptosis: an ordered cellular explosion
-
Vandenabeele, P., Galluzzi, L., Vanden Berghe, T., and Kroemer, G. (2010). Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat. Rev. Mol. Cell Biol. 11, 700-714.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 700-714
-
-
Vandenabeele, P.1
Galluzzi, L.2
Vanden Berghe, T.3
Kroemer, G.4
-
72
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
Ventura, A., Kirsch, D. G., McLaughlin, M. E., Tuveson, D. A., Grimm, J., Lintault, L., Newman, J., Reczek, E. E., Weissleder, R., and Jacks, T. (2007). Restoration of p53 function leads to tumour regression in vivo. Nature 445, 661-665.
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
Tuveson, D.A.4
Grimm, J.5
Lintault, L.6
Newman, J.7
Reczek, E.E.8
Weissleder, R.9
Jacks, T.10
-
73
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen, D., Beyaert, R., Denecker, G., Goossens, V., Van Loo, G., Declercq, W., Grooten, J., Fiers, W., and Vandenabeele, P. (1998a). Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J. Exp. Med. 187, 1477-1485.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
Goossens, V.4
Van Loo, G.5
Declercq, W.6
Grooten, J.7
Fiers, W.8
Vandenabeele, P.9
-
74
-
-
0032494143
-
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways
-
Vercammen, D., Brouckaert, G., Denecker, G., Van de Craen, M., Declercq, W., Fiers, W., and Vandenabeele, P. (1998b). Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways. J. Exp. Med. 188, 919-930.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 919-930
-
-
Vercammen, D.1
Brouckaert, G.2
Denecker, G.3
Van de Craen, M.4
Declercq, W.5
Fiers, W.6
Vandenabeele, P.7
-
75
-
-
52549087785
-
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
-
Visvader, J. E., and Lindeman, G. J. (2008). Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 8, 755-768.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
76
-
-
33846913723
-
Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5
-
Wang, K., Li, J., Degterev, A., Hsu, E., Yuan, J., and Yuan, C. (2007). Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5. Bioorg. Med. Chem. Lett. 17, 1455-1465.
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 1455-1465
-
-
Wang, K.1
Li, J.2
Degterev, A.3
Hsu, E.4
Yuan, J.5
Yuan, C.6
-
77
-
-
77956619262
-
Synergistic protective effects of humanin and necrostatin-1 on hypoxia and ischemia/reperfusion injury
-
Xu, X., Chua, K. W., Chua, C. C., Liu, C. F., Hamdy, R. C., and Chua, B. H. (2010). Synergistic protective effects of humanin and necrostatin-1 on hypoxia and ischemia/reperfusion injury. Brain Res. 1355, 189-194.
-
(2010)
Brain Res.
, vol.1355
, pp. 189-194
-
-
Xu, X.1
Chua, K.W.2
Chua, C.C.3
Liu, C.F.4
Hamdy, R.C.5
Chua, B.H.6
-
78
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue, W., Zender, L., Miething, C., Dickins, R. A., Hernando, E., Krizhanovsky, V., Cordon-Cardo, C., and Lowe, S. W. (2007). Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445, 656-660.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
79
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz, O. H., Valdez, R., Theisen, B. K., Guo, W., Ferguson, D. O., Wu, H., and Morrison, S. J. (2006). Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441, 475-482.
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
Morrison, S.J.7
-
80
-
-
50249132439
-
Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice
-
You, Z., Savitz, S. I., Yang, J., Degterev, A., Yuan, J., Cuny, G. D., Moskowitz, M. A., and Whalen, M. J. (2008). Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice. J. Cereb. Blood Flow Metab. 28, 1564-1573.
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, pp. 1564-1573
-
-
You, Z.1
Savitz, S.I.2
Yang, J.3
Degterev, A.4
Yuan, J.5
Cuny, G.D.6
Moskowitz, M.A.7
Whalen, M.J.8
-
81
-
-
0141884305
-
Diversity in the mechanisms of neuronal cell death
-
Yuan, J., Lipinski, M., and Degterev, A. (2003). Diversity in the mechanisms of neuronal cell death. Neuron 40, 401-413.
-
(2003)
Neuron
, vol.40
, pp. 401-413
-
-
Yuan, J.1
Lipinski, M.2
Degterev, A.3
-
82
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang, D. W., Shao, J., Lin, J., Zhang, N., Lu, B. J., Lin, S. C., Dong, M. Q., and Han, J. (2009). RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325, 332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
Dong, M.Q.7
Han, J.8
-
83
-
-
77950366886
-
Decoding cell death signals in inflammation and immunity
-
Zitvogel, L., Kepp, O., and Kroemer, G. (2010). Decoding cell death signals in inflammation and immunity. Cell 140, 798-804.
-
(2010)
Cell
, vol.140
, pp. 798-804
-
-
Zitvogel, L.1
Kepp, O.2
Kroemer, G.3
-
84
-
-
33748987908
-
Cancer despite immunosurveillance: immunoselection and immunosubversion
-
Zitvogel, L., Tesniere, A., and Kroemer, G. (2006). Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat. Rev. Immunol. 6, 715-727.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 715-727
-
-
Zitvogel, L.1
Tesniere, A.2
Kroemer, G.3
|