Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region

Nature Biotechnology

Volumn 25, Issue 11, 2007, Pages 1315-1321

  Ishikawa, Fumihiko ^a,b   Yoshida, Shuro ^a,b   Saito, Yoriko ^a,d   Hijikata, Atsushi ^a   Kitamura, Hiroshi ^a   Tanaka, Satoshi ^e   Nakamura, Ryu ^f   Tanaka, Toru ^f   Tomiyama, Hiroko ^e   Saito, Noriyuki ^b   Fukata, Mitsuhiro ^b   Miyamoto, Toshihiro ^c   Lyons, Bonnie ^g   Ohshima, Koichi ^h   Uchida, Naoyuki ⁱ   Taniguchi, Shuichi ⁱ   Ohara, Osamu ^a,j   Akashi, Koichi ^c,k   Harada, Mine ^b   Shultz, Leonard D ^g  

^a RIKEN Center for Integrative Medical Sciences   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY HOSPITAL   (Japan)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e Nippon Becton Dickinson   (Japan)

^f Carl Zeiss Co Ltd   (Japan)

^g JACKSON LABORATORY   (United States)

^h KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ TORANOMON HOSPITAL   (Japan)

^j KAZUSA DNA RESEARCH INSTITUTE   (Japan)

^k HARVARD MEDICAL SCHOOL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CHEMOTHERAPY; CLONING; CYTOTOXICITY; DISEASES; TRANSPLANTATION (SURGICAL);

ACUTE MYELOGENOUS LEUKEMIA (AML); NEWBORN NONOBESE DIABETIC (NOD); SEVERE COMBINED IMMUNODEFICIENT (SCID); XENOTRANSPLANTATION;

CELL DEATH;

CYTARABINE; CYTOKINE;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW; CELL CYCLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; GENE EXPRESSION; HEMATOPOIESIS; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; XENOTRANSPLANTATION;

ANIMALS; APOPTOSIS; BONE MARROW; CELL DIVISION; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION PROFILING; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, MUTANT STRAINS; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; OSTEOBLASTS;

MUS;

EID: 35948984135     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1350     Document Type: Article

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