메뉴 건너뛰기




Volumn 206, Issue 2, 2013, Pages 279-288

Interplay between apoptosis and autophagy, a challenging puzzle: New perspectives on antitumor chemotherapies

Author keywords

Anticancer therapies; Autophagy; Cell death; Drug resistance; Metastasis

Indexed keywords

2 DEOXY 5 AZACYTIDINE; ALKALOID; ARSENIC TRIOXIDE; BAFILOMYCIN A1; CATHA EDULIS EXTRACT; CHLOROQUINE; CISPLATIN; DAPORINAD; DEXAMETHASONE; DNA METHYLTRANSFERASE INHIBITOR; DOCETAXEL; DOXORUBICIN; ERLOTINIB; EUPALININ A; EVEROLIMUS; FLUOROURACIL; HYDROXYCHLOROQUINE; IMATINIB; LETROZOLE; OBATOCLAX; PHOTOSENSITIZING AGENT; PHYTOALEXIN; PLATONIN; RAPAMYCIN; TAMOXIFEN; TRASTUZUMAB; TRIFLUOPERAZINE; TRITERPENOID; UNCLASSIFIED DRUG; UNINDEXED DRUG; VOACAMINE;

EID: 84885990962     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.09.018     Document Type: Review
Times cited : (46)

References (122)
  • 3
    • 34547186029 scopus 로고    scopus 로고
    • Apoptosis regulation by autophagy gene 5
    • DOI 10.1016/j.critrevonc.2007.06.005, PII S104084280700114X
    • S. Yousefi, and H.-U. Simon Apoptosis regulation by autophagy gene 5 Crit. Rev. Oncol./Hemato. 63 2007 241 244 (Pubitemid 47126867)
    • (2007) Critical Reviews in Oncology/Hematology , vol.63 , Issue.3 , pp. 241-244
    • Yousefi, S.1    Simon, H.-U.2
  • 4
    • 0037005262 scopus 로고    scopus 로고
    • Autophagosome formation in mammalian cells
    • DOI 10.1247/csf.27.421
    • N. Mizushima, Y. Ohsumi, and T. Yoshimori Autophagosome formation in mammalian cells Cell Struct. Funct. 27 2002 421 429 (Pubitemid 36267711)
    • (2002) Cell Structure and Function , vol.27 , Issue.6 , pp. 421-429
    • Mizushima, N.1    Ohsumi, Y.2    Yoshimori, T.3
  • 5
    • 84555195856 scopus 로고    scopus 로고
    • Autophagy mitochondria and oxidative stress cross-talk and redox signalling
    • J. Lee, S. Giordano, and J. Zhang Autophagy mitochondria and oxidative stress cross-talk and redox signalling Biochem. J. 441 2012 523 540
    • (2012) Biochem. J. , vol.441 , pp. 523-540
    • Lee, J.1    Giordano, S.2    Zhang, J.3
  • 6
    • 84861671713 scopus 로고    scopus 로고
    • Lysosomal pathways to cell death and their therapeutic applications
    • M.H. Česen, K. Pegan, A. Spes, and B. Turk Lysosomal pathways to cell death and their therapeutic applications Exp. Cell Res. 318 2012 1245 1251
    • (2012) Exp. Cell Res. , vol.318 , pp. 1245-1251
    • Česen, M.H.1    Pegan, K.2    Spes, A.3    Turk, B.4
  • 7
    • 84863523132 scopus 로고    scopus 로고
    • Differential induction of autophagy in caspase-3/7 down-regulating and Bcl-2 overexpressing recombinant CHO cells subjected to sodium butyrate treatment
    • J.S. Lee, Y.J. Kim, C.L. Kim, and G.M. Lee Differential induction of autophagy in caspase-3/7 down-regulating and Bcl-2 overexpressing recombinant CHO cells subjected to sodium butyrate treatment J. Biotechnol. 161 2012 34 41
    • (2012) J. Biotechnol. , vol.161 , pp. 34-41
    • Lee, J.S.1    Kim, Y.J.2    Kim, C.L.3    Lee, G.M.4
  • 8
    • 33847048316 scopus 로고    scopus 로고
    • Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
    • DOI 10.2353/ajpath.2007.060524
    • J.H. Zhu, C. Horbinski, F. Guo, S. Watkins, Y. Uchiyama, and C.T. Chu Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death The Am. J. Pathol. 170 2007 75 86 (Pubitemid 47339191)
    • (2007) American Journal of Pathology , vol.170 , Issue.1 , pp. 75-86
    • Zhu, J.-H.1    Horbinski, C.2    Guo, F.3    Watkins, S.4    Uchiyama, Y.5    Chu, C.T.6
  • 9
    • 78651298893 scopus 로고    scopus 로고
    • The Autophagy Database: An all-inclusive information resource on autophagy that provides nourishment for research
    • K. Homma, K. Suzuki, and H. Sugawara The Autophagy Database: an all-inclusive information resource on autophagy that provides nourishment for research Nucleic Acids Res. 39 2011 D986 D990
    • (2011) Nucleic Acids Res. , vol.39
    • Homma, K.1    Suzuki, K.2    Sugawara, H.3
  • 10
    • 77951911179 scopus 로고    scopus 로고
    • Regulation of autophagy in mammals and its interplay with apoptosis
    • G.M. Fimia, and M. Piacentini Regulation of autophagy in mammals and its interplay with apoptosis Cell Mol. Life Sci. 67 2010 1581 1588
    • (2010) Cell Mol. Life Sci. , vol.67 , pp. 1581-1588
    • Fimia, G.M.1    Piacentini, M.2
  • 11
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • DOI 10.1016/j.cell.2006.01.016, PII S0092867406001085
    • S. Wullschleger, R. Loewith, and M.N. Hall TOR signaling in growth and metabolism Cell 10 2006 471 484 (Pubitemid 43199434)
    • (2006) Cell , vol.124 , Issue.3 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 13
    • 36448968532 scopus 로고    scopus 로고
    • FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells
    • DOI 10.1016/j.cmet.2007.11.004, PII S1550413107003397
    • J. Zhao, J.J. Brault, A. Schild, P. Cao, M. Sandri, S. Schiaffino, S.H. Lecker, and A.L. Goldberg FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells Cell Metab. 6 2007 472 483 (Pubitemid 350163056)
    • (2007) Cell Metabolism , vol.6 , Issue.6 , pp. 472-483
    • Zhao, J.1    Brault, J.J.2    Schild, A.3    Cao, P.4    Sandri, M.5    Schiaffino, S.6    Lecker, S.H.7    Goldberg, A.L.8
  • 14
    • 66449114033 scopus 로고    scopus 로고
    • P62 at the crossroads of autophagy, apoptosis, and cancer
    • J. Moscat, and M.T. Diaz-Meco p62 at the crossroads of autophagy, apoptosis, and cancer Cell 137 2009 1001 1004
    • (2009) Cell , vol.137 , pp. 1001-1004
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 16
    • 22344444616 scopus 로고    scopus 로고
    • Does autophagy contribute to cell death?
    • J. Debnath, E.H. Baehrecke, and G. Kroemer Does autophagy contribute to cell death? Autophagy 1 2005 66 74
    • (2005) Autophagy , vol.1 , pp. 66-74
    • Debnath, J.1    Baehrecke, E.H.2    Kroemer, G.3
  • 17
    • 77951768486 scopus 로고    scopus 로고
    • Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
    • Y. Sancak, L. Bar-Peled, R. Zoncu, A.L. Markhard, S. Nada, and D.M. Sabatini Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids Cell 141 2010 290 303
    • (2010) Cell , vol.141 , pp. 290-303
    • Sancak, Y.1    Bar-Peled, L.2    Zoncu, R.3    Markhard, A.L.4    Nada, S.5    Sabatini, D.M.6
  • 19
    • 80555143078 scopus 로고    scopus 로고
    • MTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
    • R. Zoncu, L. Bar-Peled, A. Efeyan, S. Wang, Y. Sancak, and D.M. Sabatini MTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase Science 334 2011 678 683
    • (2011) Science , vol.334 , pp. 678-683
    • Zoncu, R.1    Bar-Peled, L.2    Efeyan, A.3    Wang, S.4    Sancak, Y.5    Sabatini, D.M.6
  • 25
    • 79955755460 scopus 로고    scopus 로고
    • Conversation between apoptosis and autophagy: "is it your turn or mine?
    • V. Giansanti, A. Torriglia, and A.I. Scovassi Conversation between apoptosis and autophagy: "Is it your turn or mine? Apoptosis 16 2011 321 333
    • (2011) Apoptosis , vol.16 , pp. 321-333
    • Giansanti, V.1    Torriglia, A.2    Scovassi, A.I.3
  • 26
    • 84859161154 scopus 로고    scopus 로고
    • Microautophagy lesses-known self-eating
    • W.W. Li, J. Li, and J.K. Bao Microautophagy lesses-known self-eating Cell Mol Life Sci. 69 2012 1125 1136
    • (2012) Cell Mol Life Sci. , vol.69 , pp. 1125-1136
    • Li, W.W.1    Li, J.2    Bao, J.K.3
  • 27
    • 0344142468 scopus 로고    scopus 로고
    • Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
    • DOI 10.1006/geno.1999.5851
    • V.M. Aita, X.H. Liang, V.V. Murty, D.L. Pincus, W. Yu, E. Cayanis, S. Kalachikov, T.C. Gilliam, and B. Levine Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21 Genomics 59 1999 59 65 (Pubitemid 29339873)
    • (1999) Genomics , vol.59 , Issue.1 , pp. 59-65
    • Aita, V.M.1    Liang, X.H.2    Murty, V.V.V.S.3    Pincus, D.L.4    Yu, W.5    Cayanis, E.6    Kalachikov, S.7    Gilliam, T.C.8    Levine, B.9
  • 29
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1
    • X.H. Liang, S. Jackson, M. Seaman, K. Brown, B. Kempkes, H. Hibshoosh, and B. Levine Induction of autophagy and inhibition of tumorigenesis by beclin 1 Nature 402 1999 672 676 (Pubitemid 129516338)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3    Brown, K.4    Kempkes, B.5    Hibshoosh, H.6    Levine, B.7
  • 30
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • DOI 10.1038/nrc1692, PII N1692
    • Y. Kondo, T. Kanzawa, R. Sawaya, and S. Kondo The role of autophagy in cancer development and response to therapy Nat. Rev. Cancer 5 2005 726 734 (Pubitemid 41486365)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.9 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4
  • 31
    • 34547132328 scopus 로고    scopus 로고
    • Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
    • DOI 10.1074/jbc.M701194200
    • G. Mariño, N. Salvador-Montoliu, A. Fueyo, E. Knecht, N. Mizushima, and C. López-Otín Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3 J. Biol. Chem. 282 2007 18573 18583 (Pubitemid 47100226)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.25 , pp. 18573-18583
    • Marino, G.1    Salvador-Montoliu, N.2    Fueyo, A.3    Knecht, E.4    Mizushima, N.5    Lopez-Otin, C.6
  • 34
    • 33745751085 scopus 로고    scopus 로고
    • Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
    • C. Liang, P. Feng, B. Ku, I. Dotan, D. Canaani, B.H. Oh, and J.U. Jung Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG Nat. Cell Biol. 8 2006 688 699
    • (2006) Nat. Cell Biol. , vol.8 , pp. 688-699
    • Liang, C.1    Feng, P.2    Ku, B.3    Dotan, I.4    Canaani, D.5    Oh, B.H.6    Jung, J.U.7
  • 36
    • 41249084239 scopus 로고    scopus 로고
    • The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis
    • DOI 10.1016/j.ccr.2008.02.001, PII S1535610808000421
    • A. Duran, J.F. Linares, A.S. Galvez, K. Wikenheiser, J.M. Flores, M.T. Diaz-Meco, and J. Moscat The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis Cancer Cell 13 2008 343 354 (Pubitemid 351446193)
    • (2008) Cancer Cell , vol.13 , Issue.4 , pp. 343-354
    • Duran, A.1    Linares, J.F.2    Galvez, A.S.3    Wikenheiser, K.4    Flores, J.M.5    Diaz-Meco, M.T.6    Moscat, J.7
  • 37
    • 84859562694 scopus 로고    scopus 로고
    • Targeting autophagy addiction in cancer
    • J.D. Mancias, and A.C. Kimmelman Targeting autophagy addiction in cancer Oncotarget. 2 2011 1302 1306
    • (2011) Oncotarget. , vol.2 , pp. 1302-1306
    • Mancias, J.D.1    Kimmelman, A.C.2
  • 38
    • 78649634631 scopus 로고    scopus 로고
    • Targeting apoptotic and autophagic pathways for cancer therapeutics
    • J.J. Liu, M. Lin, J.Y. Yu, B. Liu, and J.K. Bao Targeting apoptotic and autophagic pathways for cancer therapeutics Cancer Lett. 300 2011 105 114
    • (2011) Cancer Lett. , vol.300 , pp. 105-114
    • Liu, J.J.1    Lin, M.2    Yu, J.Y.3    Liu, B.4    Bao, J.K.5
  • 39
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • J.F. Kerr, A.H. Wyllie, and A.R. Currie Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics Br. J. Cancer 26 1972 239 257
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 40
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • G. Kroemer, G. Mariño, and B. Levine Autophagy and the integrated stress response Mol. Cell 40 2010 280 293
    • (2010) Mol. Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Mariño, G.2    Levine, B.3
  • 41
    • 34147193472 scopus 로고    scopus 로고
    • Cell biology: Autophagy and cancer
    • DOI 10.1038/446745a, PII 446745A
    • B. Levine Cell biology: autophagy and cancer Nature 446 2007 745 747 (Pubitemid 46582063)
    • (2007) Nature , vol.446 , Issue.7137 , pp. 745-747
    • Levine, B.1
  • 42
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumor suppressor mechanism
    • DOI 10.1038/sj.onc.1207521
    • D. Gozuacik, and A. Kimchi Autophagy as a cell death and tumor suppressor mechanism Oncogene 23 2004 2891 2906 (Pubitemid 38638851)
    • (2004) Oncogene , vol.23 , Issue.16 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 43
    • 0038743077 scopus 로고    scopus 로고
    • Induction of autophagic cell death in malignant glioma cells by arsenic trioxide
    • T. Kanzawa, Y. Kondo, H. Ito, S. Kondo, and I. Germano Induction of autophagic cell death in malignant glioma cells by arsenic trioxide Cancer Res. 63 2003 2103 2108 (Pubitemid 36538613)
    • (2003) Cancer Research , vol.63 , Issue.9 , pp. 2103-2108
    • Kanzawa, T.1    Kondo, Y.2    Ito, H.3    Kondo, S.4    Germano, I.5
  • 44
    • 27644514227 scopus 로고    scopus 로고
    • Another way to die: Autophagic programmed cell death
    • DOI 10.1038/sj.cdd.4401777, PII 4401777
    • Y. Tsujimoto, and S. Shimizu Another way to die: autophagic programmed cell death Cell Death Differ. 12 2005 1528 1534 (Pubitemid 41553989)
    • (2005) Cell Death and Differentiation , vol.12 , Issue.SUPPL. 2 , pp. 1528-1534
    • Tsujimoto, Y.1    Shimizu, S.2
  • 45
    • 33746359639 scopus 로고    scopus 로고
    • The death-associated protein kinases: Structure, function, and beyond
    • DOI 10.1146/annurev.biochem.75.103004.142615
    • S. Bialik, and A. Kimchi The death-associated protein kinases: structure, function, and beyond Annu. Rev. Biochem. 75 2006 189 210 (Pubitemid 44118031)
    • (2006) Annual Review of Biochemistry , vol.75 , pp. 189-210
    • Bialik, S.1    Kimchi, A.2
  • 46
    • 61849102389 scopus 로고    scopus 로고
    • DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy
    • E. Zalckvar, H. Berissi, L. Mizrachy, Y. Idelchuk, I. Koren, M. Eisenstein, H. Sabanay, R. Pinkas-Kramarski, and A. Kimchi DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy EMBO Rep. 10 2009 285 292
    • (2009) EMBO Rep. , vol.10 , pp. 285-292
    • Zalckvar, E.1    Berissi, H.2    Mizrachy, L.3    Idelchuk, Y.4    Koren, I.5    Eisenstein, M.6    Sabanay, H.7    Pinkas-Kramarski, R.8    Kimchi, A.9
  • 47
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • R. Kang, H.J. Zeh, M.T. Lotze, and D. Tang The Beclin 1 network regulates autophagy and apoptosis Cell Death Differ. 18 2011 571 580
    • (2011) Cell Death Differ. , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 48
    • 84859766593 scopus 로고    scopus 로고
    • Novel insights into the interplay between apoptosis and autophagy
    • H. Rikiishi Novel insights into the interplay between apoptosis and autophagy Int. J. Cell Biol. 2 2012 317645
    • (2012) Int. J. Cell Biol. , vol.2 , pp. 317645
    • Rikiishi, H.1
  • 49
  • 50
    • 78651282673 scopus 로고    scopus 로고
    • P62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
    • E. Itakura, and N. Mizushima p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding J. Cell Biol. 192 2011 17 27
    • (2011) J. Cell Biol. , vol.192 , pp. 17-27
    • Itakura, E.1    Mizushima, N.2
  • 51
    • 84862257733 scopus 로고    scopus 로고
    • The crosstalk between autophagy and apoptosis: Where does this lead?
    • C. Gordy, and Y.W. He The crosstalk between autophagy and apoptosis: where does this lead? Protein Cell 3 2012 17 27
    • (2012) Protein Cell , vol.3 , pp. 17-27
    • Gordy, C.1    He, Y.W.2
  • 52
    • 84872076250 scopus 로고    scopus 로고
    • A cellular stress-directed bistable switch controls the crosstalk between autophagy and apoptosis
    • O. Kapuy, P.K. Vinod, J. Mandl, and G. Bánhegyi A cellular stress-directed bistable switch controls the crosstalk between autophagy and apoptosis Mol. Biosyst. 9 2013 296 306
    • (2013) Mol. Biosyst. , vol.9 , pp. 296-306
    • Kapuy, O.1    Vinod, P.K.2    Mandl, J.3    Bánhegyi, G.4
  • 53
    • 62449287501 scopus 로고    scopus 로고
    • The paradox of autophagy and its implication in cancer etiology and therapy
    • A. Eisenberg-Lerner, and A. Kimchi The paradox of autophagy and its implication in cancer etiology and therapy Apoptosis 14 2009 376 391
    • (2009) Apoptosis , vol.14 , pp. 376-391
    • Eisenberg-Lerner, A.1    Kimchi, A.2
  • 54
    • 37849026130 scopus 로고    scopus 로고
    • The daily job of night killers: Alternative roles of the BCL-2 family in organelle physiology
    • C. Hetz, and L. Glimcher The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology Trends Cell Biol. 18 2008 38 44
    • (2008) Trends Cell Biol. , vol.18 , pp. 38-44
    • Hetz, C.1    Glimcher, L.2
  • 55
    • 77953858790 scopus 로고    scopus 로고
    • TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin 1 to control TLR4-induced autophagy
    • C.S. Shi, and J.H. Kehrl TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin 1 to control TLR4-induced autophagy Sci. Signal 3 2010 ra42
    • (2010) Sci. Signal , vol.3 , pp. 42
    • Shi, C.S.1    Kehrl, J.H.2
  • 57
    • 84874238503 scopus 로고    scopus 로고
    • Cisplatin-induced apoptosis inhibits autophagy, which acts as a pro-survival mechanism in human melanoma cells
    • B. Del Bello, M. Toscano, D. Moretti, and E. Maellaro Cisplatin-induced apoptosis inhibits autophagy, which acts as a pro-survival mechanism in human melanoma cells PLOS ONE 8 2013 e57236
    • (2013) PLOS ONE , vol.8 , pp. 57236
    • Del Bello, B.1    Toscano, M.2    Moretti, D.3    Maellaro, E.4
  • 58
    • 33745282435 scopus 로고    scopus 로고
    • Sulforaphane causes autophagy to inhibit release of cytochrome c and apoptosis in human prostate cancer cells
    • DOI 10.1158/0008-5472.CAN-06-0139
    • A. Herman-Antosiewicz, D.E. Johnson, and S.V. Singh Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells Cancer Res. 66 2006 5828 5835 (Pubitemid 43927137)
    • (2006) Cancer Research , vol.66 , Issue.11 , pp. 5828-5835
    • Herman-Antosiewicz, A.1    Johnson, D.E.2    Singh, S.V.3
  • 59
    • 34147141497 scopus 로고    scopus 로고
    • Switch between apoptosis and autophagy: Radiation-induced endoplasmic reticulum stress?
    • L. Moretti, Y.I. Cha, K.J. Niermann, and B. Lu Switch between apoptosis and autophagy: radiation-induced endoplasmic reticulum stress? Cell Cycle 6 2007 793 798 (Pubitemid 46572616)
    • (2007) Cell Cycle , vol.6 , Issue.7 , pp. 793-798
    • Moretti, L.1    Cha, Y.I.2    Niermann, K.J.3    Lu, B.4
  • 60
    • 33745864334 scopus 로고    scopus 로고
    • Deficiency in apoptotic effectors Bax and Bak reveals an autophagic cell death pathway initiated by photodamage to the endoplasmic reticulum
    • E. Buytaert, G. Callewaert, J.R. Vandenheede, and P. Agostinis Deficiency in apoptotic effectors Bax and Bak reveals an autophagic cell death pathway initiated by photodamage to the endoplasmic reticulum Autophagy 2 2006 238 240 (Pubitemid 44030895)
    • (2006) Autophagy , vol.2 , Issue.3 , pp. 238-240
    • Buytaert, E.1    Callewaert, G.2    Vandenheede, J.R.3    Agostinis, P.4
  • 61
    • 48249123422 scopus 로고    scopus 로고
    • M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models
    • K.W. Kim, L. Moretti, and B. Lu M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models PLoS One 3 2008 e2275
    • (2008) PLoS One , vol.3 , pp. 2275
    • Kim, K.W.1    Moretti, L.2    Lu, B.3
  • 63
    • 17444405985 scopus 로고    scopus 로고
    • Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells
    • DOI 10.1038/sj.onc.1208421
    • A. Essafi, S. Fernández de Mattos, Y.A. Hassen, I. Soeiro, G.J. Mufti, N.S. Thomas, R.H. Medema, and E.W. Lam Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells Oncogene 24 2005 2317 2329 (Pubitemid 40546691)
    • (2005) Oncogene , vol.24 , Issue.14 , pp. 2317-2329
    • Essafi, A.1    Fernandez De Mattos, S.2    Hassen, Y.A.M.3    Soeiro, I.4    Mufti, G.J.5    Thomas, N.S.B.6    Medema, R.H.7    Lam, E.W.-F.8
  • 65
    • 34347394714 scopus 로고    scopus 로고
    • Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHAto overcome Bcr-Abl-mediated drug resistance
    • DOI 10.1182/blood-2006-10-050260
    • J.S. Carew, S.T. Nawrocki, C.N. Kahue, H. Zhang, C. Yang, L. Chung, J.A. Houghton, P. Huang, F.J. Giles, and J.L. Cleveland Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance Blood 110 2007 313 322 (Pubitemid 47026849)
    • (2007) Blood , vol.110 , Issue.1 , pp. 313-322
    • Carew, J.S.1    Nawrocki, S.T.2    Kahue, C.N.3    Zhang, H.4    Yang, C.5    Chung, L.6    Houghton, J.A.7    Huang, P.8    Giles, F.J.9    Cleveland, J.L.10
  • 66
    • 80052643889 scopus 로고    scopus 로고
    • BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription
    • Z. Sheng, L. Ma, J.E. Sun, L.J. Zhu, and M.R. Green BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription Blood 118 2011 2840 2848
    • (2011) Blood , vol.118 , pp. 2840-2848
    • Sheng, Z.1    Ma, L.2    Sun, J.E.3    Zhu, L.J.4    Green, M.R.5
  • 67
    • 76249124608 scopus 로고    scopus 로고
    • Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
    • A. Puissant, G. Robert, N. Fenouille, F. Luciano, J.P. Cassuto, S. Raynaud, and P. Auberger Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation Cancer Res. 70 2010 1042 1052
    • (2010) Cancer Res. , vol.70 , pp. 1042-1052
    • Puissant, A.1    Robert, G.2    Fenouille, N.3    Luciano, F.4    Cassuto, J.P.5    Raynaud, S.6    Auberger, P.7
  • 68
    • 67650252764 scopus 로고    scopus 로고
    • RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia
    • R. Crazzolara, K.F. Bradstock, and L.J. Bendall RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia Autophagy 5 2009 727 728
    • (2009) Autophagy , vol.5 , pp. 727-728
    • Crazzolara, R.1    Bradstock, K.F.2    Bendall, L.J.3
  • 69
    • 38549083274 scopus 로고    scopus 로고
    • Eupalinin A isolated from Eupatorium chinense L. Induces autophagocytosis in human leukemia HL60 cells
    • T. Itoh, Y. Ito, K. Ohguchi, M. Ohyama, M. Iinuma, Y. Otsuki, Y. Nozawa, and Y. Akao Eupalinin A isolated from Eupatorium chinense L. induces autophagocytosis in human leukemia HL60 cells Bioorg. Med. Chem. 16 2008 721 723
    • (2008) Bioorg. Med. Chem. , vol.16 , pp. 721-723
    • Itoh, T.1    Ito, Y.2    Ohguchi, K.3    Ohyama, M.4    Iinuma, M.5    Otsuki, Y.6    Nozawa, Y.7    Akao, Y.8
  • 70
    • 75649113906 scopus 로고    scopus 로고
    • Camptothecin and khat (Catha edulisForsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines
    • T. Bredholt, E.A. Dimba, H.R. Hagland, L. Wergeland, J. Skavland, K.O. Fossan, K.J. Tronstad, A.C. Johannessen, O.K. Vintermyr, and B.T. Gjertsen Camptothecin and khat (Catha edulisForsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines Mol Cancer. 8 2009 101
    • (2009) Mol Cancer. , vol.8 , pp. 101
    • Bredholt, T.1    Dimba, E.A.2    Hagland, H.R.3    Wergeland, L.4    Skavland, J.5    Fossan, K.O.6    Tronstad, K.J.7    Johannessen, A.C.8    Vintermyr, O.K.9    Gjertsen, B.T.10
  • 71
    • 49849093594 scopus 로고    scopus 로고
    • Inhibition of mitochondrial metabolism by methyl-2-cyano-3,12- dioxooleana-1,9-diene-28-oate induces apoptotic or autophagic cell death in chronic myeloid leukemia cells
    • I. Samudio, S. Kurinna, P. Ruvolo, B. Korchin, H. Kantarjian, M. Beran, K. JrDunner, S. Kondo, M. Andreeff, and M. Konopleva Inhibition of mitochondrial metabolism by methyl-2-cyano-3,12-dioxooleana-1,9-diene-28-oate induces apoptotic or autophagic cell death in chronic myeloid leukemia cells Mol Cancer Ther. 7 2008 1130 1139
    • (2008) Mol Cancer Ther. , vol.7 , pp. 1130-1139
    • Samudio, I.1    Kurinna, S.2    Ruvolo, P.3    Korchin, B.4    Kantarjian, H.5    Beran, M.6    Jrdunner, K.7    Kondo, S.8    Andreeff, M.9    Konopleva, M.10
  • 76
    • 37849028908 scopus 로고    scopus 로고
    • Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells
    • Y.P. Yang, Z.Q. Liang, B. Gao, Y.L. Jia, and Z.H. Qin Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells Acta Pharmacol. Sin. 29 2008 123 134
    • (2008) Acta Pharmacol. Sin. , vol.29 , pp. 123-134
    • Yang, Y.P.1    Liang, Z.Q.2    Gao, B.3    Jia, Y.L.4    Qin, Z.H.5
  • 77
    • 77956898610 scopus 로고    scopus 로고
    • Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide
    • D.J. Goussetis, J.K. Altman, H. Glaser, J.L. McNeer, M.S. Tallman, and L.C. Platanias Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide J. Biol. Chem. 285 2010 29989 29997
    • (2010) J. Biol. Chem. , vol.285 , pp. 29989-29997
    • Goussetis, D.J.1    Altman, J.K.2    Glaser, H.3    McNeer, J.L.4    Tallman, M.S.5    Platanias, L.C.6
  • 78
    • 78650710470 scopus 로고    scopus 로고
    • Sustained exposure to the DNA demethylating agent, 2'-deoxy-5- azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy
    • M. Schnekenburger, C. Grandjenette, J. Ghelfi, T. Karius, B. Foliguet, M. Dicato, and M. Diederich Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy Biochem. Pharmacol. 81 2011 364 378
    • (2011) Biochem. Pharmacol. , vol.81 , pp. 364-378
    • Schnekenburger, M.1    Grandjenette, C.2    Ghelfi, J.3    Karius, T.4    Foliguet, B.5    Dicato, M.6    Diederich, M.7
  • 80
    • 77957688352 scopus 로고    scopus 로고
    • The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy
    • Y. Wei, T. Kadia, W. Tong, M. Zhang, Y. Jia, H. Yang, Y. Hu, J. Viallet, S. O'Brien, and G. Garcia-Manero The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy Autophagy 6 2010 976 978
    • (2010) Autophagy , vol.6 , pp. 976-978
    • Wei, Y.1    Kadia, T.2    Tong, W.3    Zhang, M.4    Jia, Y.5    Yang, H.6    Hu, Y.7    Viallet, J.8    O'Brien, S.9    Garcia-Manero, G.10
  • 86
  • 87
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • DOI 10.1038/nrm2239, PII NRM2239
    • M.C. Maiuri, E. Zalckvar, A. Kimchi, and G. Kroemer Self-eating and self-killing: crosstalk between autophagy and apoptosis Nat. Rev. Mol. Cell Biol. 8 2007 741 752 (Pubitemid 47312826)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 88
    • 79953659370 scopus 로고    scopus 로고
    • Autophagy blockade enhances HDAC inhibitors' pro-apoptotic effects: Potential implications for the treatment of a therapeutic-resistant malignancy
    • G. Lopez, K. Torres, and D. Lev Autophagy blockade enhances HDAC inhibitors' pro-apoptotic effects: potential implications for the treatment of a therapeutic-resistant malignancy Autophagy 7 2011 440 441
    • (2011) Autophagy , vol.7 , pp. 440-441
    • Lopez, G.1    Torres, K.2    Lev, D.3
  • 92
    • 84862793242 scopus 로고    scopus 로고
    • Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells
    • C. Hu, M.J. Zou, L. Zhao, N. Lu, Y.J. Sun, S.H. Gou, T. Xi, and Q.L. Guo Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells Toxicol. Lett. 210 2012 78 86
    • (2012) Toxicol. Lett. , vol.210 , pp. 78-86
    • Hu, C.1    Zou, M.J.2    Zhao, L.3    Lu, N.4    Sun, Y.J.5    Gou, S.H.6    Xi, T.7    Guo, Q.L.8
  • 93
    • 67650885510 scopus 로고    scopus 로고
    • Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab
    • A. Vazquez-Martin, C. Oliveras-Ferraros, and J.A. Menendez Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab PLoS One 4 2009 e6251
    • (2009) PLoS One , vol.4 , pp. 6251
    • Vazquez-Martin, A.1    Oliveras-Ferraros, C.2    Menendez, J.A.3
  • 97
    • 64549086420 scopus 로고    scopus 로고
    • Short hairpin RNA (shRNA) constructs targeting high mobility group box-1 (HMGB1) expression leads to inhibition of prostate cancer cell survival and apoptosis
    • M. Gnanasekar, S. Thirugnanam, and K. Ramaswamy Short hairpin RNA (shRNA) constructs targeting high mobility group box-1 (HMGB1) expression leads to inhibition of prostate cancer cell survival and apoptosis Int. J. Oncol. 34 2009 425 431
    • (2009) Int. J. Oncol. , vol.34 , pp. 425-431
    • Gnanasekar, M.1    Thirugnanam, S.2    Ramaswamy, K.3
  • 98
    • 33846799065 scopus 로고    scopus 로고
    • Autophagy-mediated chemosensitizing effect of the plant alkaloid voacamine on multidrug resistant cells
    • DOI 10.1016/j.tiv.2006.09.007, PII S0887233306001913
    • S. Meschini, M. Condello, M. Marra, G. Formisano, E. Federici, and G. Arancia Autophagy mediated chemosensitizing effect of the plant alkaloid voacamine on multidrug resistant cells Toxicol. In Vitro 21 2007 197 203 (Pubitemid 46205082)
    • (2007) Toxicology in Vitro , vol.21 , Issue.2 , pp. 197-203
    • Meschini, S.1    Condello, M.2    Marra, M.3    Formisano, G.4    Federici, E.5    Arancia, G.6
  • 99
    • 48249090416 scopus 로고    scopus 로고
    • Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer
    • K.W. Kim, M. Hwang, L. Moretti, J.J. Jaboin, Y.I. Cha, and B. Lu Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer Autophagy 4 2008 659 668
    • (2008) Autophagy , vol.4 , pp. 659-668
    • Kim, K.W.1    Hwang, M.2    Moretti, L.3    Jaboin, J.J.4    Cha, Y.I.5    Lu, B.6
  • 100
    • 67349286024 scopus 로고    scopus 로고
    • Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line
    • R. Mazzanti, F. Platini, C. Bottini, O. Fantappiè, M. Solazzo, and L. Tessitore Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line Biochem. Pharmacol. 78 2009 21 32
    • (2009) Biochem. Pharmacol. , vol.78 , pp. 21-32
    • Mazzanti, R.1    Platini, F.2    Bottini, C.3    Fantappiè, O.4    Solazzo, M.5    Tessitore, L.6
  • 101
    • 84856857494 scopus 로고    scopus 로고
    • Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells
    • G.M. Ajabnoor, T. Crook, and H.M. Coley Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells Cell Death Dis. 3 2012 1 9
    • (2012) Cell Death Dis. , vol.3 , pp. 1-9
    • Ajabnoor, G.M.1    Crook, T.2    Coley, H.M.3
  • 102
    • 84863985893 scopus 로고    scopus 로고
    • Long-term cisplatin exposure impairs autophagy and causes cisplatin resistance in human lung cancer cells
    • B. Sirichanchuen, T. Pengsuparp, and P. Chanvorachote Long-term cisplatin exposure impairs autophagy and causes cisplatin resistance in human lung cancer cells Mol. Cell. Biochem. 364 2012 11 18
    • (2012) Mol. Cell. Biochem. , vol.364 , pp. 11-18
    • Sirichanchuen, B.1    Pengsuparp, T.2    Chanvorachote, P.3
  • 103
    • 80051696767 scopus 로고    scopus 로고
    • Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2
    • J.H. Ahn, and M. Lee Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2 Cancer Lett. 310 2011 188 197
    • (2011) Cancer Lett. , vol.310 , pp. 188-197
    • Ahn, J.H.1    Lee, M.2
  • 104
    • 84862494695 scopus 로고    scopus 로고
    • The different regulatory effects of p53 status on multidrug resistance are determined by autophagy in ovarian cancer cells
    • D. Kong, S. Ma, B. Liang, H. Yi, Y. Zhao, R. Xin, L. Cui, L. Jia, X. Liu, and X. Liu The different regulatory effects of p53 status on multidrug resistance are determined by autophagy in ovarian cancer cells Biomed. Pharmacother. 66 2012 271 278
    • (2012) Biomed. Pharmacother. , vol.66 , pp. 271-278
    • Kong, D.1    Ma, S.2    Liang, B.3    Yi, H.4    Zhao, Y.5    Xin, R.6    Cui, L.7    Jia, L.8    Liu, X.9    Liu, X.10
  • 105
    • 77953289524 scopus 로고    scopus 로고
    • Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model
    • J. Li, N. Hou, A. Faried, S. Tsutsumi, and H. Kuwano Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model Eur. J. Cancer 46 2010 1900 1909
    • (2010) Eur. J. Cancer , vol.46 , pp. 1900-1909
    • Li, J.1    Hou, N.2    Faried, A.3    Tsutsumi, S.4    Kuwano, H.5
  • 106
    • 60449092595 scopus 로고    scopus 로고
    • Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells
    • J. Li, N. Hou, A. Faried, S. Tsutsumi, and H. Kuwano Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells Ann. Surg. Oncol. 16 2009 761 771
    • (2009) Ann. Surg. Oncol. , vol.16 , pp. 761-771
    • Li, J.1    Hou, N.2    Faried, A.3    Tsutsumi, S.4    Kuwano, H.5
  • 108
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • J.A. Joyce, and J.W. Pollard Microenvironmental regulation of metastasis Nat. Rev. Cancer 9 2009 239 252
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 109
  • 110
    • 50849088969 scopus 로고    scopus 로고
    • Extracellular matrix regulation of autophagy
    • R. Lock, and J. Debnath Extracellular matrix regulation of autophagy Curr. Opin. Cell Biol. 20 2008 583 588
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 583-588
    • Lock, R.1    Debnath, J.2
  • 112
    • 50349098812 scopus 로고    scopus 로고
    • Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells
    • J. Han, W. Hou, L.A. Goldstein, C. Lu, D.B. Stolz, X.M. Yin, and H. Rabinowich Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells J. Biol. Chem. 283 2008 19665 19677
    • (2008) J. Biol. Chem. , vol.283 , pp. 19665-19677
    • Han, J.1    Hou, W.2    Goldstein, L.A.3    Lu, C.4    Stolz, D.B.5    Yin, X.M.6    Rabinowich, H.7
  • 113
    • 79953725166 scopus 로고    scopus 로고
    • Overexpression of microtubule-associated protein-1 light chain 3 is associated with melanoma metastasis and vasculogenic mimicry
    • C. Han, B. Sun, W. Wang, W. Cai, D. Lou, Y. Sun, and X. Zhao Overexpression of microtubule-associated protein-1 light chain 3 is associated with melanoma metastasis and vasculogenic mimicry Tohoku J. Exp. Med. 223 2011 243 251
    • (2011) Tohoku J. Exp. Med. , vol.223 , pp. 243-251
    • Han, C.1    Sun, B.2    Wang, W.3    Cai, W.4    Lou, D.5    Sun, Y.6    Zhao, X.7
  • 114
    • 84858750402 scopus 로고    scopus 로고
    • Long term induction by pterostilbene results in autophagy and cellular differentiation in MCF-7 cells via ROS dependent pathway
    • A. Chakraborty, N. Bodipati, M.K. Demonacos, R. Peddinti, K. Ghosh, and P. Roy Long term induction by pterostilbene results in autophagy and cellular differentiation in MCF-7 cells via ROS dependent pathway Mol. Cell Endocrinol. 355 2012 25 40
    • (2012) Mol. Cell Endocrinol. , vol.355 , pp. 25-40
    • Chakraborty, A.1    Bodipati, N.2    Demonacos, M.K.3    Peddinti, R.4    Ghosh, K.5    Roy, P.6
  • 115
  • 116
    • 80053372589 scopus 로고    scopus 로고
    • C-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells
    • T. Sun, D. Li, L. Wang, L. Xia, J. Ma, Z. Guan, G. Feng, and X. Zhu C-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells J. Transl. Med. 9 2011 161 171
    • (2011) J. Transl. Med. , vol.9 , pp. 161-171
    • Sun, T.1    Li, D.2    Wang, L.3    Xia, L.4    Ma, J.5    Guan, Z.6    Feng, G.7    Zhu, X.8
  • 118
  • 119
    • 0024602207 scopus 로고
    • Effect of a malaria suppression program on the incidence of African Burkitt's lymphoma
    • A. Geser, G. Brubaker, and C.C. Draper Effect of a malaria suppression program on the incidence of African Burkitt's lymphoma Am. J. Epidemiol. 129 1989 740 752 (Pubitemid 19094252)
    • (1989) American Journal of Epidemiology , vol.129 , Issue.4 , pp. 740-752
    • Geser, A.1    Brubaker, G.2    Draper, C.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.