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Volumn 14, Issue 3, 2007, Pages 500-510

Autophagy delays apoptotic death in breast cancer cells following DNA damage

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; CAMPTOTHECIN; CASPASE; CASPASE 9; PROTEIN ATG7; PROTEIN BECLIN; PROTEIN BIMEL; PROTEIN NOXA; PROTEIN P53; PROTEIN PUMA; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 33847026354     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4402039     Document Type: Article
Times cited : (463)

References (40)
  • 1
    • 0035575679 scopus 로고    scopus 로고
    • Programmed cell death: Alive and well in the new millennium
    • Kaufmann SH, Hengartner MO. Programmed cell death: Alive and well in the new millennium. Trends Cell Biol 2001; 11: 526-534.
    • (2001) Trends Cell Biol , vol.11 , pp. 526-534
    • Kaufmann, S.H.1    Hengartner, M.O.2
  • 3
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumor suppressor mechanism
    • Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 2004; 23: 2891-2906.
    • (2004) Oncogene , vol.23 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 4
    • 0038309329 scopus 로고    scopus 로고
    • The molecular mechanism of autophagy
    • Wang CW, Klionsky DJ. The molecular mechanism of autophagy. Mol Med 2003; 9: 65-76.
    • (2003) Mol Med , vol.9 , pp. 65-76
    • Wang, C.W.1    Klionsky, D.J.2
  • 5
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams JM, Cory S. The Bcl-2 protein family: Arbiters of cell survival. Science 1998; 281: 1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 6
    • 0033635733 scopus 로고    scopus 로고
    • BH3-Only proteins-essential initiators of apoptotic cell death
    • Huang DC, Strasser A. BH3-Only proteins-essential initiators of apoptotic cell death. Cell 2000; 103: 839-842.
    • (2000) Cell , vol.103 , pp. 839-842
    • Huang, D.C.1    Strasser, A.2
  • 7
    • 0032146987 scopus 로고    scopus 로고
    • Bcl-2-family proteins: The role of the BH3 domain in apoptosis
    • Kelekar A, Thompson CB. Bcl-2-family proteins: The role of the BH3 domain in apoptosis. Trends Cell Biol 1998; 8: 324-330.
    • (1998) Trends Cell Biol , vol.8 , pp. 324-330
    • Kelekar, A.1    Thompson, C.B.2
  • 8
    • 4644250606 scopus 로고    scopus 로고
    • Cytoplasmic p53: Bax and forward
    • Chipuk JE, Green DR. Cytoplasmic p53: Bax and forward. Cell Cycle 2004; 3: 429-431.
    • (2004) Cell Cycle , vol.3 , pp. 429-431
    • Chipuk, J.E.1    Green, D.R.2
  • 9
    • 13944257800 scopus 로고    scopus 로고
    • Transcription, apoptosis and p53: Catch-22
    • Schuler M, Green DR. Transcription, apoptosis and p53: Catch-22. Trends Genet 2005; 21: 182-187.
    • (2005) Trends Genet , vol.21 , pp. 182-187
    • Schuler, M.1    Green, D.R.2
  • 10
    • 0242664660 scopus 로고    scopus 로고
    • UV-induced apoptosis is mediated independent of caspase-9 in MCF-7 cells: A model for cytochrome c resistance
    • Ferguson HA, Marietta PM, Van Den Berg CL. UV-induced apoptosis is mediated independent of caspase-9 in MCF-7 cells: A model for cytochrome c resistance. J Biol Chem 2003; 278: 45793-45800.
    • (2003) J Biol Chem , vol.278 , pp. 45793-45800
    • Ferguson, H.A.1    Marietta, P.M.2    Van Den Berg, C.L.3
  • 11
    • 0037016723 scopus 로고    scopus 로고
    • Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells
    • Kottke TJ, Blajeski AL, Meng XW, Svingen PA, Ruchaud S, Mesner Jr PW et al. Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells. J Biol Chem 2002; 277: 804-815.
    • (2002) J Biol Chem , vol.277 , pp. 804-815
    • Kottke, T.J.1    Blajeski, A.L.2    Meng, X.W.3    Svingen, P.A.4    Ruchaud, S.5    Mesner Jr., P.W.6
  • 12
    • 17144409080 scopus 로고    scopus 로고
    • Multi-probe RPA template sets to study RNA modulation and transcriptional control of BH3-only members of the Bcl-2 family
    • Wang D, McDonnell MA, Kelekar A. Multi-probe RPA template sets to study RNA modulation and transcriptional control of BH3-only members of the Bcl-2 family. Cancer Detect Prev 2005; 29: 189-200.
    • (2005) Cancer Detect Prev , vol.29 , pp. 189-200
    • Wang, D.1    McDonnell, M.A.2    Kelekar, A.3
  • 13
    • 0038482050 scopus 로고    scopus 로고
    • Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
    • Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ. Activation of the ERK1/ 2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 2003; 278: 18811-18816.
    • (2003) J Biol Chem , vol.278 , pp. 18811-18816
    • Ley, R.1    Balmanno, K.2    Hadfield, K.3    Weston, C.4    Cook, S.J.5
  • 14
    • 0842278331 scopus 로고    scopus 로고
    • Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    • Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M et al. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 2004; 303: 1010-1014.
    • (2004) Science , vol.303 , pp. 1010-1014
    • Chipuk, J.E.1    Kuwana, T.2    Bouchier-Hayes, L.3    Droin, N.M.4    Newmeyer, D.D.5    Schuler, M.6
  • 16
    • 0035487007 scopus 로고    scopus 로고
    • The mitochondrial permeability transition initiates autophagy in rat hepatocytes
    • Elmore SP, Qian T, Grissom SF, Lemasters JJ. The mitochondrial permeability transition initiates autophagy in rat hepatocytes. FASEB J 2001; 15: 2286-2287.
    • (2001) FASEB J , vol.15 , pp. 2286-2287
    • Elmore, S.P.1    Qian, T.2    Grissom, S.F.3    Lemasters, J.J.4
  • 17
    • 0842305108 scopus 로고    scopus 로고
    • Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer
    • Elmore SP, Nishimura Y, Qian T, Herman B, Lemasters JJ. Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer. Arch Biochem Biophys 2004; 422: 145-152.
    • (2004) Arch Biochem Biophys , vol.422 , pp. 145-152
    • Elmore, S.P.1    Nishimura, Y.2    Qian, T.3    Herman, B.4    Lemasters, J.J.5
  • 18
    • 0035863399 scopus 로고    scopus 로고
    • A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
    • Paglin S, Hollister T, Delohery T, Hackett N, McMahill M, Sphicas E et al. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 2001; 61: 439-444.
    • (2001) Cancer Res , vol.61 , pp. 439-444
    • Paglin, S.1    Hollister, T.2    Delohery, T.3    Hackett, N.4    McMahill, M.5    Sphicas, E.6
  • 19
    • 2442485884 scopus 로고    scopus 로고
    • Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
    • Scarlatti F, Bauvy C, Ventruti A, Sala G, Cluzeaud F, Vandewalle A et al. Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1. J Biol Chem 2004; 279: 18384-18391.
    • (2004) J Biol Chem , vol.279 , pp. 18384-18391
    • Scarlatti, F.1    Bauvy, C.2    Ventruti, A.3    Sala, G.4    Cluzeaud, F.5    Vandewalle, A.6
  • 20
    • 0028836002 scopus 로고
    • Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles
    • Biederbick A, Kern HF, Elsasser HP. Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol 1995; 66: 3-14.
    • (1995) Eur J Cell Biol , vol.66 , pp. 3-14
    • Biederbick, A.1    Kern, H.F.2    Elsasser, H.P.3
  • 21
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19: 5720-5728.
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6
  • 24
    • 0001488499 scopus 로고    scopus 로고
    • Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
    • Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G et al. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol 1998; 72: 8586-8596.
    • (1998) J Virol , vol.72 , pp. 8586-8596
    • Liang, X.H.1    Kleeman, L.K.2    Jiang, H.H.3    Gordon, G.4    Goldman, J.E.5    Berry, G.6
  • 25
    • 0035870257 scopus 로고    scopus 로고
    • Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function
    • Liang XH, Yu J, Brown K, Levine B. Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function. Cancer Res 2001; 61: 3443-3449.
    • (2001) Cancer Res , vol.61 , pp. 3443-3449
    • Liang, X.H.1    Yu, J.2    Brown, K.3    Levine, B.4
  • 26
    • 0032168167 scopus 로고    scopus 로고
    • Etoposide: Four decades of development of a topoisomerase II inhibitor
    • Hande KR. Etoposide: Four decades of development of a topoisomerase II inhibitor. Eur J Cancer 1998; 34: 1514-1521.
    • (1998) Eur J Cancer , vol.34 , pp. 1514-1521
    • Hande, K.R.1
  • 27
    • 21044455137 scopus 로고    scopus 로고
    • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
    • Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 2005; 169: 425-434.
    • (2005) J Cell Biol , vol.169 , pp. 425-434
    • Komatsu, M.1    Waguri, S.2    Ueno, T.3    Iwata, J.4    Murata, S.5    Tanida, I.6
  • 29
    • 84940133922 scopus 로고
    • Tissue culture and scanning electron microscopy of breast carcinoma 'cell line MCF-7' from pleural effusion
    • Rizk NN, El-Rakhawy MT. Tissue culture and scanning electron microscopy of breast carcinoma 'cell line MCF-7' from pleural effusion. Acta Anat (Basel) 1981; 109: 70-74.
    • (1981) Acta Anat (Basel) , vol.109 , pp. 70-74
    • Rizk, N.N.1    El-Rakhawy, M.T.2
  • 30
    • 4344712684 scopus 로고    scopus 로고
    • Methods for monitoring autophagy
    • Mizushima N. Methods for monitoring autophagy. Int J Biochem Cell Biol 2004; 36: 2491-2502.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2491-2502
    • Mizushima, N.1
  • 31
    • 7444243152 scopus 로고    scopus 로고
    • Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity
    • Harada H, Quearry B, Ruiz-Vela A, Korsmeyer SJ. Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity. Proc Natl Acad Sci USA 2004; 101: 15313-15317.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15313-15317
    • Harada, H.1    Quearry, B.2    Ruiz-Vela, A.3    Korsmeyer, S.J.4
  • 32
    • 0038056194 scopus 로고    scopus 로고
    • Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis
    • Seward RJ, von Haller PD, Aebersold R, Huber BT. Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis. Mol Immunol 2003; 39: 983-993.
    • (2003) Mol Immunol , vol.39 , pp. 983-993
    • Seward, R.J.1    von Haller, P.D.2    Aebersold, R.3    Huber, B.T.4
  • 33
    • 0037037328 scopus 로고    scopus 로고
    • Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells
    • Mooney LM, Al-Sakkaf KA, Brown BL, Dobson PR. Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells. Br J Cancer 2002; 87: 909-917.
    • (2002) Br J Cancer , vol.87 , pp. 909-917
    • Mooney, L.M.1    Al-Sakkaf, K.A.2    Brown, B.L.3    Dobson, P.R.4
  • 34
    • 0344142468 scopus 로고    scopus 로고
    • Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
    • Aita VM, Liang XH, Murty VV, Pincus DL, Yu W, Cayanis E et al. Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics 1999; 59: 59-65.
    • (1999) Genomics , vol.59 , pp. 59-65
    • Aita, V.M.1    Liang, X.H.2    Murty, V.V.3    Pincus, D.L.4    Yu, W.5    Cayanis, E.6
  • 35
    • 0035032723 scopus 로고    scopus 로고
    • Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
    • Kihara A, Kabeya Y, Ohsumi Y, Yoshimori T. Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep 2001; 2: 330-335.
    • (2001) EMBO Rep , vol.2 , pp. 330-335
    • Kihara, A.1    Kabeya, Y.2    Ohsumi, Y.3    Yoshimori, T.4
  • 36
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122: 927-939.
    • (2005) Cell , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Liang, X.H.5    Mizushima, N.6
  • 37
    • 0029741890 scopus 로고    scopus 로고
    • Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: The role of autophagy
    • Bursch W, Ellinger A, Kienzl H, Torok L, Pandey S, Sikorska M et al. Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: The role of autophagy. Carcinogenesis 1996; 17: 1595-1607.
    • (1996) Carcinogenesis , vol.17 , pp. 1595-1607
    • Bursch, W.1    Ellinger, A.2    Kienzl, H.3    Torok, L.4    Pandey, S.5    Sikorska, M.6
  • 38
    • 0037451783 scopus 로고    scopus 로고
    • Autophagy: A barrier or an adaptive response to cancer
    • Ogier-Denis E, Codogno P. Autophagy: A barrier or an adaptive response to cancer. Biochim Biophys Acta 2003; 1603: 113-128.
    • (2003) Biochim Biophys Acta , vol.1603 , pp. 113-128
    • Ogier-Denis, E.1    Codogno, P.2
  • 39
    • 0027282044 scopus 로고
    • bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993; 74: 597-608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3    Ding, L.4    Lindsten, T.5    Turka, L.A.6
  • 40
    • 0033522391 scopus 로고    scopus 로고
    • Conformation of the Bax C-terminus regulates subcellular location and cell death
    • Nechushtan A, Smith CL, Hsu YT, Youle RJ. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J 1999; 18: 2330-2341.
    • (1999) EMBO J , vol.18 , pp. 2330-2341
    • Nechushtan, A.1    Smith, C.L.2    Hsu, Y.T.3    Youle, R.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.