메뉴 건너뛰기




Volumn 6, Issue 3, 2010, Pages 395-404

Elevated Beclin 1 expression is correlated with HIF-1α in predicting poor prognosis of nasopharyngeal carcinoma

Author keywords

Autophagy; Beclin 1; HIF 1 ; Nasopharyngeal carcinoma; Prognostic marker

Indexed keywords

BECLIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

EID: 77953708091     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.6.3.11303     Document Type: Article
Times cited : (124)

References (56)
  • 1
    • 20444472028 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma
    • Wei WI, Sham JS. Nasopharyngeal carcinoma. Lancet 2005; 365:2041-54.
    • (2005) Lancet , vol.365 , pp. 2041-2054
    • Wei, W.I.1    Sham, J.S.2
  • 2
    • 33750532057 scopus 로고    scopus 로고
    • The enigmatic epidemiology of nasopharyngeal carcinoma
    • Chang ET, Adami HO. The enigmatic epidemiology of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev 2006; 15:1765-77.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 1765-1777
    • Chang, E.T.1    Adami, H.O.2
  • 3
    • 14544304586 scopus 로고    scopus 로고
    • Long-term survival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma a pooled data analysis of two phase III trials
    • Chua DT, Ma J, Sham JS, Mai HQ, Choy DT, Hong MH, et al. Long-term survival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: a pooled data analysis of two phase III trials. J Clin Oncol 2005; 23:1118-24.
    • (2005) J Clin Oncol , vol.23 , pp. 1118-1124
    • Chua, D.T.1    Ma, J.2    Sham, J.S.3    Mai, H.Q.4    Choy, D.T.5    Hong, M.H.6
  • 4
    • 4644345181 scopus 로고    scopus 로고
    • Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy
    • Chua DT, Nicholls JM, Sham JS, Au GK. Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy. Int J Radiat Oncol Biol Phys 2004; 59:11-20.
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 11-20
    • Chua, D.T.1    Nicholls, J.M.2    Sham, J.S.3    Au, G.K.4
  • 5
    • 33846892784 scopus 로고    scopus 로고
    • Centromere protein H is a novel prognostic marker for nasopharyngeal carcinoma progression and overall patient survival
    • Liao WT, Song LB, Zhang HZ, Zhang X, Zhang L, Liu WL, et al. Centromere protein H is a novel prognostic marker for nasopharyngeal carcinoma progression and overall patient survival. Clin Cancer Res 2007; 13:508-14.
    • (2007) Clin Cancer Res , vol.13 , pp. 508-514
    • Liao, W.T.1    Song, L.B.2    Zhang, H.Z.3    Zhang, X.4    Zhang, L.5    Liu, W.L.6
  • 6
    • 71049134844 scopus 로고    scopus 로고
    • PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma
    • Fendri A, Khabir A, Mnejja W, Sellami-Boudawara T, Daoud J, Frikha M, et al. PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma. Cancer Sci 2009; 100:2034-9.
    • (2009) Cancer Sci , vol.100 , pp. 2034-2039
    • Fendri, A.1    Khabir, A.2    Mnejja, W.3    Sellami-Boudawara, T.4    Daoud, J.5    Frikha, M.6
  • 7
    • 52449111395 scopus 로고    scopus 로고
    • Heterogeneous ribonucleoprotein k and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma
    • Chen LC, Hsueh C, Tsang NM, Liang Y, Chang KP, Hao SP, et al. Heterogeneous ribonucleoprotein k and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma. Clin Cancer Res 2008; 14:3807-13.
    • (2008) Clin Cancer Res , vol.14 , pp. 3807-3813
    • Chen, L.C.1    Hsueh, C.2    Tsang, N.M.3    Liang, Y.4    Chang, K.P.5    Hao, S.P.6
  • 8
    • 33847742531 scopus 로고    scopus 로고
    • Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma
    • Leung SF, Zee B, Ma BB, Hui EP, Mo F, Lai M, et al. Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma. J Clin Oncol 2006; 24:5414-8.
    • (2006) J Clin Oncol , vol.24 , pp. 5414-5418
    • Leung, S.F.1    Zee, B.2    Ma, B.B.3    Hui, E.P.4    Mo, F.5    Lai, M.6
  • 9
    • 38949112133 scopus 로고    scopus 로고
    • Identification of novel nasopharyngeal carcinoma biomarkers by laser capture microdissection and proteomic analysis
    • Cheng AL, Huang WG, Chen ZC, Peng F, Zhang PF, Li MY, et al. Identification of novel nasopharyngeal carcinoma biomarkers by laser capture microdissection and proteomic analysis. Clin Cancer Res 2008; 14:435-45.
    • (2008) Clin Cancer Res , vol.14 , pp. 435-445
    • Cheng, A.L.1    Huang, W.G.2    Chen, Z.C.3    Peng, F.4    Zhang, P.F.5    Li, M.Y.6
  • 10
    • 33748188459 scopus 로고    scopus 로고
    • Epidermal growth factor receptor biology in head and neck cancer
    • Kalyankrishna S, Grandis JR. Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol 2006; 24:2666-72.
    • (2006) J Clin Oncol , vol.24 , pp. 2666-2672
    • Kalyankrishna, S.1    Grandis, J.R.2
  • 12
    • 20644435370 scopus 로고    scopus 로고
    • Multicenter phase II study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma
    • Chan AT, Hsu MM, Goh BC, Hui EP, Liu TW, Millward MJ, et al. Multicenter, phase II study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma. J Clin Oncol 2005; 23:3568-76.
    • (2005) J Clin Oncol , vol.23 , pp. 3568-3576
    • Chan, A.T.1    Hsu, M.M.2    Goh, B.C.3    Hui, E.P.4    Liu, T.W.5    Millward, M.J.6
  • 13
    • 70349251424 scopus 로고    scopus 로고
    • Cetuximab plus radiotherapy for the treatment of locally advanced squamous cell carcinoma of the head and neck
    • Griffin S, Walker S, Sculpher M, White S, Erhorn S, Brent S, et al. Cetuximab plus radiotherapy for the treatment of locally advanced squamous cell carcinoma of the head and neck. Health Technol Assess 2009; 13:49-54.
    • (2009) Health Technol Assess , vol.13 , pp. 49-54
    • Griffin, S.1    Walker, S.2    Sculpher, M.3    White, S.4    Erhorn, S.5    Brent, S.6
  • 15
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • Klionsky DJ. Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 2007; 8:931-7.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 931-937
    • Klionsky, D.J.1
  • 16
    • 28544435485 scopus 로고    scopus 로고
    • Lysosomes and autophagy in cell death control
    • Kroemer G, Jaattela M. Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005; 5:886-97.
    • (2005) Nat Rev Cancer , vol.5 , pp. 886-897
    • Kroemer, G.1    Jaattela, M.2
  • 18
    • 48249092267 scopus 로고    scopus 로고
    • Bcl-2 family members: Dual regulators of apoptosis and autophagy
    • Levine B, Sinha S, Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 2008; 4:600-6.
    • (2008) Autophagy , vol.4 , pp. 600-606
    • Levine, B.1    Sinha, S.2    Kroemer, G.3
  • 20
    • 0001488499 scopus 로고    scopus 로고
    • Protection against fatal Sindbis virus encephalitis by beclin a novel Bcl-2-interacting protein
    • Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, et al. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol 1998; 72:8586-96.
    • (1998) J Virol , vol.72 , pp. 8586-8596
    • Liang, X.H.1    Kleeman, L.K.2    Jiang, H.H.3    Gordon, G.4    Goldman, J.E.5    Berry, G.6
  • 22
    • 43649104579 scopus 로고    scopus 로고
    • Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
    • Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, et al. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 2008; 283:10892-903.
    • (2008) J Biol Chem , vol.283 , pp. 10892-10903
    • Zhang, H.1    Bosch-Marce, M.2    Shimoda, L.A.3    Tan, Y.S.4    Baek, J.H.5    Wesley, J.B.6
  • 24
  • 25
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122:927-39.
    • (2005) Cell , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Liang, X.H.5    Mizushima, N.6
  • 27
    • 60149098492 scopus 로고    scopus 로고
    • The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells
    • Li DD, Wang LL, Deng R, Tang J, Shen Y, Guo JF, et al. The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells. Oncogene 2009; 28:886-98.
    • (2009) Oncogene , vol.28 , pp. 886-898
    • Li, D.D.1    Wang, L.L.2    Deng, R.3    Tang, J.4    Shen, Y.5    Guo, J.F.6
  • 28
    • 44949237240 scopus 로고    scopus 로고
    • JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
    • Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30:678-88.
    • (2008) Mol Cell , vol.30 , pp. 678-688
    • Wei, Y.1    Pattingre, S.2    Sinha, S.3    Bassik, M.4    Levine, B.5
  • 30
    • 34848899280 scopus 로고    scopus 로고
    • Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
    • Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol 2007; 9:1142-51.
    • (2007) Nat Cell Biol , vol.9 , pp. 1142-1151
    • Takahashi, Y.1    Coppola, D.2    Matsushita, N.3    Cualing, H.D.4    Sun, M.5    Sato, Y.6
  • 31
    • 39049194057 scopus 로고    scopus 로고
    • The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
    • Furuya N, Yu J, Byfield M, Pattingre S, Levine B. The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 2005; 1:46-52.
    • (2005) Autophagy , vol.1 , pp. 46-52
    • Furuya, N.1    Yu, J.2    Byfield, M.3    Pattingre, S.4    Levine, B.5
  • 32
    • 59249089394 scopus 로고    scopus 로고
    • Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
    • Itakura E, Kishi C, Inoue K, Mizushima N. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell 2008; 19:5360-72.
    • (2008) Mol Biol Cell , vol.19 , pp. 5360-5372
    • Itakura, E.1    Kishi, C.2    Inoue, K.3    Mizushima, N.4
  • 33
    • 40449086885 scopus 로고    scopus 로고
    • Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy
    • Apel A, Herr I, Schwarz H, Rodemann HP, Mayer A. Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res 2008; 68:1485-94.
    • (2008) Cancer Res , vol.68 , pp. 1485-1494
    • Apel, A.1    Herr, I.2    Schwarz, H.3    Rodemann, H.P.4    Mayer, A.5
  • 34
    • 35848947032 scopus 로고    scopus 로고
    • Role of autophagy in breast cancer
    • Karantza-Wadsworth V, White E. Role of autophagy in breast cancer. Autophagy 2007; 3:610-3.
    • (2007) Autophagy , vol.3 , pp. 610-613
    • Karantza-Wadsworth, V.1    White, E.2
  • 35
    • 58149084586 scopus 로고    scopus 로고
    • Decreased expression of autophagy-related proteins in malignant epithelial ovarian cancer
    • Shen Y, Li DD, Wang LL, Deng R, Zhu XF. Decreased expression of autophagy-related proteins in malignant epithelial ovarian cancer. Autophagy 2008; 4:1067-8.
    • (2008) Autophagy , vol.4 , pp. 1067-1068
    • Shen, Y.1    Li, D.D.2    Wang, L.L.3    Deng, R.4    Zhu, X.F.5
  • 36
    • 34047271129 scopus 로고    scopus 로고
    • Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours
    • Miracco C, Cosci E, Oliveri G, Luzi P, Pacenti L, Monciatti I, et al. Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours. Int J Oncol 2007; 30:429-36.
    • (2007) Int J Oncol , vol.30 , pp. 429-436
    • Miracco, C.1    Cosci, E.2    Oliveri, G.3    Luzi, P.4    Pacenti, L.5    Monciatti, I.6
  • 37
    • 65249135974 scopus 로고    scopus 로고
    • Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma
    • Shi YH, Ding ZB, Zhou J, Qiu SJ, Fan J. Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma. Autophagy 2009; 5:380-2.
    • (2009) Autophagy , vol.5 , pp. 380-382
    • Shi, Y.H.1    Ding, Z.B.2    Zhou, J.3    Qiu, S.J.4    Fan, J.5
  • 38
    • 37549063395 scopus 로고    scopus 로고
    • Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers
    • Ahn CH, Jeong EG, Lee JW, Kim MS, Kim SH, Kim SS, et al. Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers. APMIS 2007; 115:1344-9.
    • (2007) APMIS , vol.115 , pp. 1344-1349
    • Ahn, C.H.1    Jeong, E.G.2    Lee, J.W.3    Kim, M.S.4    Kim, S.H.5    Kim, S.S.6
  • 39
  • 40
    • 68149139456 scopus 로고    scopus 로고
    • The autophagy effector Beclin 1: A novel BH3-only protein
    • Sinha S, Levine B. The autophagy effector Beclin 1: a novel BH3-only protein. Oncogene 2008; 27:137-48.
    • (2008) Oncogene , vol.27 , pp. 137-148
    • Sinha, S.1    Levine, B.2
  • 41
    • 85011939836 scopus 로고    scopus 로고
    • Inhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivo
    • Yang C, Tong Y, Ni W, Liu J, Xu W, Li L, et al. Inhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivo. Cancer Gene Ther 2009.
    • (2009) Cancer Gene Ther
    • Yang, C.1    Tong, Y.2    Ni, W.3    Liu, J.4    Xu, W.5    Li, L.6
  • 42
    • 65249139482 scopus 로고    scopus 로고
    • Autophagy facilitates the progression of ERalpha-positive breast cancer cells to antiestrogen resistance
    • Schoenlein PV, Periyasamy-Thandavan S, Samaddar JS, Jackson WH, Barrett JT. Autophagy facilitates the progression of ERalpha-positive breast cancer cells to antiestrogen resistance. Autophagy 2009; 5:400-3.
    • (2009) Autophagy , vol.5 , pp. 400-403
    • Schoenlein, P.V.1    Periyasamy-Thandavan, S.2    Samaddar, J.S.3    Jackson, W.H.4    Barrett, J.T.5
  • 43
    • 48249090416 scopus 로고    scopus 로고
    • Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer
    • Kim KW, Hwang M, Moretti L, Jaboin JJ, Cha YI, Lu B. Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy 2008; 4:659-68.
    • (2008) Autophagy , vol.4 , pp. 659-668
    • Kim, K.W.1    Hwang, M.2    Moretti, L.3    Jaboin, J.J.4    Cha, Y.I.5    Lu, B.6
  • 44
    • 33845974091 scopus 로고    scopus 로고
    • Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling
    • Kim KW, Mutter RW, Cao C, Albert JM, Freeman M, Hallahan DE, Lu B. Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling. J Biol Chem 2006; 281:36883-90.
    • (2006) J Biol Chem , vol.281 , pp. 36883-36890
    • Kim, K.W.1    Mutter, R.W.2    Cao, C.3    Albert, J.M.4    Freeman, M.5    Hallahan, D.E.6    Lu, B.7
  • 45
    • 56449107131 scopus 로고    scopus 로고
    • Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma
    • Ding ZB, Shi YH, Zhou J, Qiu SJ, Xu Y, Dai Z, et al. Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma. Cancer Res 2008; 68:9167-75.
    • (2008) Cancer Res , vol.68 , pp. 9167-9175
    • Ding, Z.B.1    Shi, Y.H.2    Zhou, J.3    Qiu, S.J.4    Xu, Y.5    Dai, Z.6
  • 46
    • 65249180744 scopus 로고    scopus 로고
    • The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers
    • Li BX, Li CY, Peng RQ, Wu XJ, Wang HY, Wan DS, et al. The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers. Autophagy 2009; 5:303-6.
    • (2009) Autophagy , vol.5 , pp. 303-306
    • Li, B.X.1    Li, C.Y.2    Peng, R.Q.3    Wu, X.J.4    Wang, H.Y.5    Wan, D.S.6
  • 47
    • 63449083667 scopus 로고    scopus 로고
    • Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors
    • Chen FH, Chiang CS, Wang CC, Tsai CS, Jung SM, Lee CC, et al. Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors. Clin Cancer Res 2009; 15:1721-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 1721-1729
    • Chen, F.H.1    Chiang, C.S.2    Wang, C.C.3    Tsai, C.S.4    Jung, S.M.5    Lee, C.C.6
  • 48
    • 0036023422 scopus 로고    scopus 로고
    • Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival
    • Hui EP, Chan AT, Pezzella F, Turley H, To KF, Poon TC, et al. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res 2002; 8:2595-604.
    • (2002) Clin Cancer Res , vol.8 , pp. 2595-2604
    • Hui, E.P.1    Chan, A.T.2    Pezzella, F.3    Turley, H.4    To, K.F.5    Poon, T.C.6
  • 49
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 2007; 26:1749-60.
    • (2007) EMBO J , vol.26 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 50
    • 52149101812 scopus 로고    scopus 로고
    • Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L
    • Papandreou I, Lim AL, Laderoute K, Denko NC. Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L. Cell Death Differ 2008; 15:1572-81.
    • (2008) Cell Death Differ , vol.15 , pp. 1572-1581
    • Papandreou, I.1    Lim, A.L.2    Laderoute, K.3    Denko, N.C.4
  • 52
    • 33644849887 scopus 로고    scopus 로고
    • Endogenous markers of two separate hypoxia response pathways (hypoxia inducible factor 2alpha and carbonic anhydrase 9) are associated with radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial
    • Koukourakis MI, Bentzen SM, Giatromanolaki A, Wilson GD, Daley FM, Saunders MI, et al. Endogenous markers of two separate hypoxia response pathways (hypoxia inducible factor 2alpha and carbonic anhydrase 9) are associated with radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial. J Clin Oncol 2006; 24:727-35.
    • (2006) J Clin Oncol , vol.24 , pp. 727-735
    • Koukourakis, M.I.1    Bentzen, S.M.2    Giatromanolaki, A.3    Wilson, G.D.4    Daley, F.M.5    Saunders, M.I.6
  • 53
    • 77953410861 scopus 로고    scopus 로고
    • Induction-concurrent chemoradiotherapy versus induction chemotherapy and radiotherapy for locoregionally advanced nasopharyngeal carcinoma
    • Huang PY, Mai HQ, Luo DH, Qiu F, Li NW, Xiang YQ, et al. Induction-concurrent chemoradiotherapy versus induction chemotherapy and radiotherapy for locoregionally advanced nasopharyngeal carcinoma. Chin J Cancer 2009; 28:1033-42.
    • (2009) Chin J Cancer , vol.28 , pp. 1033-1042
    • Huang, P.Y.1    Mai, H.Q.2    Luo, D.H.3    Qiu, F.4    Li, N.W.5    Xiang, Y.Q.6
  • 55
    • 53349101074 scopus 로고    scopus 로고
    • Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells
    • Wan XB, Long ZJ, Yan M, Xu J, Xia LP, Liu L, et al. Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells. Carcinogenesis 2008; 29:1930-7.
    • (2008) Carcinogenesis , vol.29 , pp. 1930-1937
    • Wan, X.B.1    Long, Z.J.2    Yan, M.3    Xu, J.4    Xia, L.P.5    Liu, L.6
  • 56
    • 34848842992 scopus 로고    scopus 로고
    • Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer
    • Zlobec I, Steele R, Terracciano L, Jass JR, Lugli A. Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer. J Clin Pathol 2007; 60:1112-6.
    • (2007) J Clin Pathol , vol.60 , pp. 1112-1116
    • Zlobec, I.1    Steele, R.2    Terracciano, L.3    Jass, J.R.4    Lugli, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.