Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines

Molecular Cancer

Volumn 8, Issue , 2009, Pages

  Bredholt, Therese ^a   Dimba, Elizabeth A O ^b   Hagland, Hanne R ^a   Wergeland, Line ^a   Skavland, Jørn ^a   Fossan, Kjell O ^c   Tronstad, Karl J ^a   Johannessen, Anne C ^a,d   Vintermyr, Olav K ^d   Gjertsen, Bjørn T ^a,c  

^a UNIVERSITY OF BERGEN   (Norway)

^b UNIVERSITY OF NAIROBI   (Kenya)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^d HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; CASPASE 8; FLICE INHIBITORY PROTEIN; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CATHA EDULIS; CELL DEATH; CELL PROTECTION; CELL RESPIRATION; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; METABOLISM; MITOCHONDRION; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; PHYTOTHERAPY; TUMOR CELL LINE; ULTRASTRUCTURE;

BCL-2-ASSOCIATED X PROTEIN; CAMPTOTHECIN; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CATHA; CELL DEATH; CELL LINE, TUMOR; CELL RESPIRATION; CYTOPROTECTION; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; HUMANS; LEUKEMIA, MYELOID, ACUTE; MITOCHONDRIA; PHENOTYPE; PHYTOTHERAPY; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 75649113906     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-8-101     Document Type: Article

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