-
1
-
-
0037221767
-
TP53 and breast cancer
-
Borresen-Dale AL (2003) TP53 and breast cancer. Hum Mutat 21: 292-300
-
(2003)
Hum Mutat
, vol.21
, pp. 292-300
-
-
Borresen-Dale, A.L.1
-
2
-
-
0028841317
-
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability
-
Brachmann CB, Sherman JM, Devine SE, Cameron EE, Pillus L, Boeke JD (1995) The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev 9: 2888-2902
-
(1995)
Genes Dev
, vol.9
, pp. 2888-2902
-
-
Brachmann, C.B.1
Sherman, J.M.2
Devine, S.E.3
Cameron, E.E.4
Pillus, L.5
Boeke, J.D.6
-
3
-
-
33750215659
-
-
Cancer Research UK
-
CancerStats (2005) (http://info.cancerresearchuk.org/cancerstats). In Cancer Research UK
-
(2005)
-
-
-
4
-
-
0037128690
-
Isolation of a SIR-like gene, SIR-T8, that is overexpressed in thyroid carcinoma cell lines and tissues
-
de Nigris F, Cerutti J, Morelli C, Califano D, Chiariotti L, Viglietto G, Santelli G, Fusco A (2002) Isolation of a SIR-like gene, SIR-T8, that is overexpressed in thyroid carcinoma cell lines and tissues. Br J Cancer 86: 917-923
-
(2002)
Br J Cancer
, vol.86
, pp. 917-923
-
-
De Nigris, F.1
Cerutti, J.2
Morelli, C.3
Califano, D.4
Chiariotti, L.5
Viglietto, G.6
Santelli, G.7
Fusco, A.8
-
5
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith OPeacocke M, Campisi J (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92: 9363-9367
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith OPeacocke, M.10
Campisi, J.11
-
6
-
-
0037405043
-
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
-
Dryden SC, Nahhas FA, Nowak JE, Goustin AS, Tainsky MA (2003) Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Mol Cell Biol 23: 3173-3185
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3173-3185
-
-
Dryden, S.C.1
Nahhas, F.A.2
Nowak, J.E.3
Goustin, A.S.4
Tainsky, M.A.5
-
7
-
-
33744466971
-
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
-
Ford E, Voit R, Liszt G, Magin C, Grummt I, Guarente L (2006) Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev 20: 1075-1080
-
(2006)
Genes Dev
, vol.20
, pp. 1075-1080
-
-
Ford, E.1
Voit, R.2
Liszt, G.3
Magin, C.4
Grummt, I.5
Guarente, L.6
-
8
-
-
0037011656
-
SIRT8' expressed in thyroid cancer is actually SIRT7
-
Frye R (2002) 'SIRT8' expressed in thyroid cancer is actually SIRT7. Br J Cancer 87: 1479
-
(2002)
Br J Cancer
, vol.87
, pp. 1479
-
-
Frye, R.1
-
9
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
Frye RA (2000) Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 273: 793-798
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
11
-
-
0032750220
-
Diverse and dynamic functions of the Sir silencing complex
-
Guarente L (1999) Diverse and dynamic functions of the Sir silencing complex. Nat Genet 23: 281-285
-
(1999)
Nat Genet
, vol.23
, pp. 281-285
-
-
Guarente, L.1
-
12
-
-
0034193776
-
Sir2 links chromatin silencing, metabolism, and aging
-
Guarente L (2000) Sir2 links chromatin silencing, metabolism, and aging. Genes Dev 14: 1021-1026
-
(2000)
Genes Dev
, vol.14
, pp. 1021-1026
-
-
Guarente, L.1
-
13
-
-
0041829415
-
Proteomics-based identification of differentially expressed genes in human gliomas: Down-regulation of SIRT2 gene
-
Hiratsuka M, Inoue T, Toda T, Kimura N, Shirayoshi Y, Kamitani H, Watanabe T, Ohama E, Tahimic CG, Kurimasa A, Oshimura M (2003) Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. Biochem Biophys Res Commun 309: 558-566
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 558-566
-
-
Hiratsuka, M.1
Inoue, T.2
Toda, T.3
Kimura, N.4
Shirayoshi, Y.5
Kamitani, H.6
Watanabe, T.7
Ohama, E.8
Tahimic, C.G.9
Kurimasa, A.10
Oshimura, M.11
-
14
-
-
0036527775
-
Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer
-
Johnstone RW (2002) Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. Nat Rev Drug Discov 1: 287-299
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 287-299
-
-
Johnstone, R.W.1
-
15
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W (2001) Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107: 137-148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
16
-
-
0035755974
-
Histone deacetylases and cancer: Causes and therapies
-
Marks P, Rifkind RA, Richon VM, Breslow R, Miller T, Kelly WK (2001) Histone deacetylases and cancer: causes and therapies. Nat Rev Cancer 1: 194-202
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
Breslow, R.4
Miller, T.5
Kelly, W.K.6
-
17
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I (2005) Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 16: 4623-4635
-
(2005)
Mol Biol Cell
, vol.16
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
18
-
-
0034575296
-
The association between telomerase activity and hormone receptor status and p53 expression in breast cancer
-
Mokbel K, Ghilchik M, Williams G, Akbar N, Parris C, Newbold R (2000) The association between telomerase activity and hormone receptor status and p53 expression in breast cancer. Int J Surg Investig 1: 509-516
-
(2000)
Int J Surg Investig
, vol.1
, pp. 509-516
-
-
Mokbel, K.1
Ghilchik, M.2
Williams, G.3
Akbar, N.4
Parris, C.5
Newbold, R.6
-
19
-
-
0036830336
-
Senescence and epigenetic dysregulation in cancer
-
Neumeister P, Albanese C, Balent B, Greally J, Pestell RG (2002) Senescence and epigenetic dysregulation in cancer. Int J Biochem Cell Biol 34: 1475-1490
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1475-1490
-
-
Neumeister, P.1
Albanese, C.2
Balent, B.3
Greally, J.4
Pestell, R.G.5
-
20
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E (2003) The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol Cell 11: 437-444
-
(2003)
Mol Cell
, vol.11
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
21
-
-
0037108799
-
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP (2002) SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci USA 99: 13653-13658
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
Boeke, J.D.4
Feinberg, A.P.5
-
22
-
-
10744232772
-
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
-
Rose G, Dato S, Altomare K, Bellizzi D, Garasto S, Greco V, Passarino G, Feraco E, Mari V, Barbi C, BonaFe M, Franceschi C, Tan Q, Boiko S, Yashin AI, De Benedictis G (2003) Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly. Exp Gerontol 38: 1065-1070
-
(2003)
Exp Gerontol
, vol.38
, pp. 1065-1070
-
-
Rose, G.1
Dato, S.2
Altomare, K.3
Bellizzi, D.4
Garasto, S.5
Greco, V.6
Passarino, G.7
Feraco, E.8
Mari, V.9
Barbi, C.10
Bonafe, M.11
Franceschi, C.12
Tan, Q.13
Boiko, S.14
Yashin, A.I.15
De Benedictis, G.16
-
24
-
-
0038299399
-
Dolly, no longer the exception: Telomeres and implications for transplantation
-
Shiels PG, Jardine AG (2003) Dolly, no longer the exception: telomeres and implications for transplantation. Cloning Stem Cells 5: 157-160
-
(2003)
Cloning Stem Cells
, vol.5
, pp. 157-160
-
-
Shiels, P.G.1
Jardine, A.G.2
-
25
-
-
0035913903
-
SIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA (2001) hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107: 149-159
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
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