-
1
-
-
77649239864
-
The podocyte in diabetic kidney disease
-
Stitt-Cavanagh, E.; MacLeod, L.; Kennedy, C. The podocyte in diabetic kidney disease. ScientificWorldJournal, 2009, 9, 1127-1139.
-
(2009)
ScientificWorldJournal
, vol.9
, pp. 1127-1139
-
-
Stitt-Cavanagh, E.1
MacLeod, L.2
Kennedy, C.3
-
2
-
-
74249096576
-
Pathophysiology of diabetic nephropathy: Involvement of multifaceted signalling mechanism
-
Balakumar, P.; Arora, M.K.; Reddy, J.; Anand-Srivastava, M,B. Pathophysiology of diabetic nephropathy: involvement of multifaceted signalling mechanism. J. Cardiovasc. Pharmacol., 2009, 54, 129-138.
-
(2009)
J. Cardiovasc. Pharmacol.
, vol.54
, pp. 129-138
-
-
Balakumar, P.1
Arora, M.K.2
Reddy, J.3
Anand-Srivastava, M.B.4
-
3
-
-
20444476826
-
The prevention of diabetic microvascular complications of diabetes: Is there a role for lipid lowering?
-
Leiter, L.A. The prevention of diabetic microvascular complications of diabetes: is there a role for lipid lowering? Diabetes Res. Clin. Pract., 2005, 68 Suppl 2, S3-S14.
-
(2005)
Diabetes Res. Clin. Pract.
, vol.68
, Issue.SUPPL. 2
-
-
Leiter, L.A.1
-
4
-
-
0037062481
-
3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephropathy
-
Danesh, F.R.; Sadeghi, M.M.; Amro, N.; Philips, C.; Zeng, L.; Lin, S.; Sahai, A.; Kanwar, Y.S. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephropathy. Proc. Natl. Acad. Sci. U S A., 2002, 99, 8301-8305.
-
(2002)
Proc. Natl. Acad. Sci. U S A.
, vol.99
, pp. 8301-8305
-
-
Danesh, F.R.1
Sadeghi, M.M.2
Amro, N.3
Philips, C.4
Zeng, L.5
Lin, S.6
Sahai, A.7
Kanwar, Y.S.8
-
5
-
-
0141483457
-
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
-
Forbes, J.M.; Thallas, V.; Thomas, M.C.; Founds, H.W.; Burns, W.C.; Jerums, G.; Cooper, M.E. The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes. FASEB J., 2003, 17, 1762-1764.
-
(2003)
FASEB J.
, vol.17
, pp. 1762-1764
-
-
Forbes, J.M.1
Thallas, V.2
Thomas, M.C.3
Founds, H.W.4
Burns, W.C.5
Jerums, G.6
Cooper, M.E.7
-
6
-
-
0037365404
-
Treatment of diabetic nephropathy with angiotensin II receptor antagonist
-
Lewis, E.J.; Lewis, J.B. Treatment of diabetic nephropathy with angiotensin II receptor antagonist. Clin. Exp. Nephrol., 2003, 7, 1-8.
-
(2003)
Clin. Exp. Nephrol.
, vol.7
, pp. 1-8
-
-
Lewis, E.J.1
Lewis, J.B.2
-
7
-
-
9644294206
-
Continuum of renoprotection with losartan at all stages of type 2 diabetic nephropathy: A post hoc analysis of the RENAAL trial results
-
Remuzzi, G.; Ruggenenti, P.; Perna, A.; Dimitrov, B.D.; de Zeeuw, D.; Hille, D.A.; Shahinfar, S.; Carides, G.W.; Brenner, B.M. Continuum of renoprotection with losartan at all stages of type 2 diabetic nephropathy: a post hoc analysis of the RENAAL trial results. J. Am. Soc. Nephrol., 2004, 15, 3117-3125.
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 3117-3125
-
-
Remuzzi, G.1
Ruggenenti, P.2
Perna, A.3
Dimitrov, B.D.4
De Zeeuw, D.5
Hille, D.A.6
Shahinfar, S.7
Carides, G.W.8
Brenner, B.M.9
-
8
-
-
7444221237
-
Preventing microalbuminuria in type 2 diabetes
-
Ruggenenti, P.; Fassi, A.; Ilieva, A.P.; Bruno, S.; Iliev, I.P.; Brusegan, V.; Rubis, N,.; Gherardi, G.; Arnoldi, F.; Ganeva, M.; Ene-Iordache, B.; Gaspari, F.; Perna, A.; Bossi, A.; Trevisan, R.; Dodesini, A.R.; Remuzzi, G. Preventing microalbuminuria in type 2 diabetes. N. Engl. J. Med., 2004, 351, 1941-1951.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 1941-1951
-
-
Ruggenenti, P.1
Fassi, A.2
Ilieva, A.P.3
Bruno, S.4
Iliev, I.P.5
Brusegan, V.6
Rubis, N.7
Gherardi, G.8
Arnoldi, F.9
Ganeva, M.10
Ene-Iordache, B.11
Gaspari, F.12
Perna, A.13
Bossi, A.14
Trevisan, R.15
Dodesini, A.R.16
Remuzzi, G.17
-
9
-
-
5444234321
-
-
The Kidney, 7th Ed., edited by Brenner BM, Philadelphia WB Saunders
-
Parving, H.H.; Mauer, M.; Ritz, E. Diabetic nephropathy. In: The Kidney, 7th Ed., edited by Brenner BM, Philadelphia WB Saunders, p1777-1818, 2004.
-
(2004)
Diabetic Nephropathy
, pp. 1777-1818
-
-
Parving, H.H.1
Mauer, M.2
Ritz, E.3
-
10
-
-
33846454303
-
Distinguishing diabetic nephropathy from other causes of glomerulosclerosis: An update
-
Alsaad, K.O.; Herzenberg, A.M. Distinguishing diabetic nephropathy from other causes of glomerulosclerosis: an update. J. Clin. Pathol., 2007, 60, 18-26.
-
(2007)
J. Clin. Pathol.
, vol.60
, pp. 18-26
-
-
Alsaad, K.O.1
Herzenberg, A.M.2
-
11
-
-
33846678397
-
Toward a mouse model of diabetic nephropathy: Is endothelial nitric oxide synthase the missing link?
-
Quaggin, S.E.; Coffman, T.M. Toward a mouse model of diabetic nephropathy: is endothelial nitric oxide synthase the missing link? J. Am. Soc. Nephrol., 2008, 18, 364-366.
-
(2008)
J. Am. Soc. Nephrol.
, vol.18
, pp. 364-366
-
-
Quaggin, S.E.1
Coffman, T.M.2
-
12
-
-
45249108429
-
Proteinuria in diabetic kidney disease: A mechanistic viewpoint
-
Jefferson, J.A.; Shankland, S.J.; Pichler, R.H. Proteinuria in diabetic kidney disease: a mechanistic viewpoint. Kidney Int., 2008, 74, 22-36.
-
(2008)
Kidney Int.
, vol.74
, pp. 22-36
-
-
Jefferson, J.A.1
Shankland, S.J.2
Pichler, R.H.3
-
13
-
-
32444451549
-
Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes
-
Remuzzi, G.; Benigni, A.; Remuzzi, A. Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes. J. Clin. Invest., 2006, 116, 288-296.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 288-296
-
-
Remuzzi, G.1
Benigni, A.2
Remuzzi, A.3
-
14
-
-
42149122041
-
Properties of the glomerular barrier and mechanisms of proteinuria
-
Haraldsson, B.; Nyström, J.; Deen, W.M. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev., 2008, 88, 451-487.
-
(2008)
Physiol Rev.
, vol.88
, pp. 451-487
-
-
Haraldsson, B.1
Nyström, J.2
Deen, W.M.3
-
15
-
-
0023550339
-
The glomerular mesangial cell: An expanding role for a specialized pericyte
-
Schlondorff, D. The glomerular mesangial cell: an expanding role for a specialized pericyte. FASEB J., 1987, 1, 272-281.
-
(1987)
FASEB J.
, vol.1
, pp. 272-281
-
-
Schlondorff, D.1
-
17
-
-
54949158787
-
New insights into the mechanisms of fibrosis and sclerosis in diabetic nephropathy
-
Brosius, F.C. 3rd. New insights into the mechanisms of fibrosis and sclerosis in diabetic nephropathy. Rev. Endocr. Metab. Disord., 2008, 9, 245-254.
-
(2008)
Rev. Endocr. Metab. Disord.
, vol.9
, pp. 245-254
-
-
Brosius III, F.C.1
-
18
-
-
34250006557
-
The spectrum of podocytopathies: A unifying view of glomerular diseases
-
Wiggins, R.C. The spectrum of podocytopathies: a unifying view of glomerular diseases. Kidney Int., 2007, 71, 1205-1214.
-
(2007)
Kidney Int.
, vol.71
, pp. 1205-1214
-
-
Wiggins, R.C.1
-
19
-
-
77950517549
-
Toward the development of podocyte-specific drugs
-
Reiser, J.; Gupta, V.; Kistler, A.D. Toward the development of podocyte-specific drugs. Kidney Int., 2010, 77, 662-668.
-
(2010)
Kidney Int.
, vol.77
, pp. 662-668
-
-
Reiser, J.1
Gupta, V.2
Kistler, A.D.3
-
20
-
-
0025829825
-
The pathogenesis of chronic renal failure in diabetic nephropathy. Investigation of 488 cases of diabetic glomerulosclerosis
-
Bohle, A.; Wehrmann, M.; Bogenschütz, O.; Batz, C.; Müller, C.A.; Müller, G.A. The pathogenesis of chronic renal failure in diabetic nephropathy. Investigation of 488 cases of diabetic glomerulosclerosis. Pathol. Res. Pract., 1991, 187, 251-259.
-
(1991)
Pathol. Res. Pract.
, vol.187
, pp. 251-259
-
-
Bohle, A.1
Wehrmann, M.2
Bogenschütz, O.3
Batz, C.4
Müller, C.A.5
Müller, G.A.6
-
21
-
-
0032710966
-
Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria
-
Meyer, T.W.; Bennett, P.H.; Nelson, R.G. Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria. Diabetologia, 1999, 42, 1341-1344.
-
(1999)
Diabetologia
, vol.42
, pp. 1341-1344
-
-
Meyer, T.W.1
Bennett, P.H.2
Nelson, R.G.3
-
22
-
-
0036789206
-
Podocyte number in normotensive type 1 diabetic patients with albuminuria
-
White, K.E.; Bilous, R.W.; Marshall, S.M.; El Nahas, M.; Remuzzi, G.; Piras, G.; De Cosmo, S.; Viberti, G. Podocyte number in normotensive type 1 diabetic patients with albuminuria. Diabetes, 2002, 51, 3083-3089.
-
(2002)
Diabetes
, vol.51
, pp. 3083-3089
-
-
White, K.E.1
Bilous, R.W.2
Marshall, S.M.3
El Nahas, M.4
Remuzzi, G.5
Piras, G.6
De Cosmo, S.7
Viberti, G.8
-
23
-
-
0031029379
-
Podocyte loss and progressive glomerular injury in type II diabetes
-
Pagtalunan, M.E.; Miller, P.L.; Jumping-Eagle, S.; Nelson, R.G.; Myers, B.D.; Rennke, H.G.; Coplon, N.S.; Sun, L.; Meyer, T.W. Podocyte loss and progressive glomerular injury in type II diabetes. J. Clin. Invest., 1997, 99, 342-348.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 342-348
-
-
Pagtalunan, M.E.1
Miller, P.L.2
Jumping-Eagle, S.3
Nelson, R.G.4
Myers, B.D.5
Rennke, H.G.6
Coplon, N.S.7
Sun, L.8
Meyer, T.W.9
-
24
-
-
0034608937
-
Transforming growth factor beta contributes to progressive diabetic nephropathy
-
Reeves, W.B.; Andreoli, T.E. Transforming growth factor beta contributes to progressive diabetic nephropathy. Proc. Natl. Acad. Sci. U S A., 2000, 97, 7667-7669.
-
(2000)
Proc. Natl. Acad. Sci. U S A.
, vol.97
, pp. 7667-7669
-
-
Reeves, W.B.1
Andreoli, T.E.2
-
25
-
-
33748999280
-
Recent insights into experimental mouse models of diabetic nephropathy
-
Tesch, G.H.; Nikolic-Paterson, D.J. Recent insights into experimental mouse models of diabetic nephropathy. Nephron. Exp. Nephrol., 2006, 104, e57-e62.
-
(2006)
Nephron. Exp. Nephrol.
, vol.104
-
-
Tesch, G.H.1
Nikolic-Paterson, D.J.2
-
26
-
-
72149132250
-
Animal models of diabetic uropathy
-
Daneshgari, F.; Leiter, E.H.; Liu, G.; Reeder, J. Animal models of diabetic uropathy. J. Urol., 2009, 182, S8-S13.
-
(2009)
J. Urol.
, vol.182
-
-
Daneshgari, F.1
Leiter, E.H.2
Liu, G.3
Reeder, J.4
-
27
-
-
0037947656
-
Diabetic kidney disease in the db/db mouse
-
Sharma, K.; McCue, P.; Dunn, S.R. Diabetic kidney disease in the db/db mouse. Am. J. Physiol. Renal. Physiol., 2003, 284, F1138-F1144.
-
(2003)
Am. J. Physiol. Renal. Physiol.
, vol.284
-
-
Sharma, K.1
McCue, P.2
Dunn, S.R.3
-
28
-
-
3142626673
-
Use of genetic mouse models in the study of diabetic nephropathy
-
Allen, T.J.; Cooper, M.E.; Lan, H.Y. Use of genetic mouse models in the study of diabetic nephropathy. Curr. Atheroscler. Rep., 2004, 6, 197-202.
-
(2004)
Curr. Atheroscler. Rep.
, vol.6
, pp. 197-202
-
-
Allen, T.J.1
Cooper, M.E.2
Lan, H.Y.3
-
29
-
-
79551520659
-
Recent insights into diabetic renal injury from the db/db mouse model of type 2 diabetic nephropathy
-
Tesch, G.H.; Lim, A.K. Recent insights into diabetic renal injury from the db/db mouse model of type 2 diabetic nephropathy. Am. J. Physiol. Renal. Physiol., 2011, 300, F301-F310.
-
(2011)
Am. J. Physiol. Renal. Physiol.
, vol.300
-
-
Tesch, G.H.1
Lim, A.K.2
-
30
-
-
12144264716
-
Transforming growth factorbeta: A clinical target for the treatment of diabetic nephropathy
-
McGowan, T.A.; Zhu, Y.; Sharma, K. Transforming growth factorbeta: a clinical target for the treatment of diabetic nephropathy. Curr. Diab. Rep., 2004, 4, 447-454.
-
(2004)
Curr. Diab. Rep.
, vol.4
, pp. 447-454
-
-
McGowan, T.A.1
Zhu, Y.2
Sharma, K.3
-
31
-
-
0347511753
-
Mediators of diabetic renal disease: The case for tgf-Beta as the major mediator
-
Ziyadeh, F.N. Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator. J. Am. Soc. Nephrol., 2004, 15 Suppl 1, S55-S57.
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, Issue.SUPPL. 1
-
-
Ziyadeh, F.N.1
-
32
-
-
0027394256
-
MRNA expression of growth factors in glomeruli from diabetic rats
-
Nakamura, T.; Fukui, M.; Ebihara, I.; Osada, S.; Nagaoka, I.; Tomino, Y.; Koide, H. mRNA expression of growth factors in glomeruli from diabetic rats. Diabetes, 1993, 42, 450-456.
-
(1993)
Diabetes
, vol.42
, pp. 450-456
-
-
Nakamura, T.1
Fukui, M.2
Ebihara, I.3
Osada, S.4
Nagaoka, I.5
Tomino, Y.6
Koide, H.7
-
33
-
-
0031053824
-
Expression of transforming growth factor-beta and type IV collagen in early streptozotocin-induced diabetes
-
Park, I.S.; Kiyomoto, H.; Abboud, S.L.; Abboud, H.E. Expression of transforming growth factor-beta and type IV collagen in early streptozotocin-induced diabetes. Diabetes, 1999, 46, 473-480.
-
(1999)
Diabetes
, vol.46
, pp. 473-480
-
-
Park, I.S.1
Kiyomoto, H.2
Abboud, S.L.3
Abboud, H.E.4
-
34
-
-
0031656012
-
Evidence that TGF-beta should be a therapeutic target in diabetic nephropathy
-
Border, W.A.; Noble, N.A. Evidence that TGF-beta should be a therapeutic target in diabetic nephropathy. Kidney Int., 1998, 54, 1390-1391.
-
(1998)
Kidney Int.
, vol.54
, pp. 1390-1391
-
-
Border, W.A.1
Noble, N.A.2
-
35
-
-
80052317444
-
The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy
-
Hills, C.E.; Squires, P.E. The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy. Cytokine Growth Factor Rev., 2011, 22, 131-139.
-
(2011)
Cytokine Growth Factor Rev.
, vol.22
, pp. 131-139
-
-
Hills, C.E.1
Squires, P.E.2
-
36
-
-
0034608948
-
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice
-
Ziyadeh, F.N.; Hoffman, B.B.; Han, D.C.; Iglesias-De La Cruz, M.C.; Hong, S.W.; Isono, M.; Chen, S.; McGowan, T.A.; Sharma, K. Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice. Proc. Natl. Acad. Sci. U S A., 2000, 97, 8015-8020.
-
(2000)
Proc. Natl. Acad. Sci. U S A.
, vol.97
, pp. 8015-8020
-
-
Ziyadeh, F.N.1
Hoffman, B.B.2
Han, D.C.3
Iglesias-De La Cruz, M.C.4
Hong, S.W.5
Isono, M.6
Chen, S.7
McGowan, T.A.8
Sharma, K.9
-
37
-
-
0029924637
-
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice
-
Sharma, K.; Jin, Y.; Guo, J.; Ziyadeh, F.N. Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes, 1996, 45, 522-530.
-
(1996)
Diabetes
, vol.45
, pp. 522-530
-
-
Sharma, K.1
Jin, Y.2
Guo, J.3
Ziyadeh, F.N.4
-
38
-
-
0034827951
-
Transforming growth factor-beta2 antibody attenuates fibrosis in the experimental diabetic rat kidney
-
Hill, C.; Flyvbjerg, A.; Rasch, R.; Bak, M.; Logan, A. Transforming growth factor-beta2 antibody attenuates fibrosis in the experimental diabetic rat kidney. J. Endocrinol., 2001, 170, 647-651.
-
(2001)
J. Endocrinol.
, vol.170
, pp. 647-651
-
-
Hill, C.1
Flyvbjerg, A.2
Rasch, R.3
Bak, M.4
Logan, A.5
-
39
-
-
33845365039
-
Beneficial effect of TGF-beta antagonism in treating diabetic nephropathy depends on when treatment is started
-
Benigni, A.; Zoja, C.; Campana, M.; Corna, D.; Sangalli, F.; Rottoli, D.; Gagliardini, E.; Conti, S.; Ledbetter, S.; Remuzzi, G. Beneficial effect of TGF-beta antagonism in treating diabetic nephropathy depends on when treatment is started. Nephron. Exp. Nephrol., 2006, 104, e158-e168.
-
(2006)
Nephron. Exp. Nephrol.
, vol.104
-
-
Benigni, A.1
Zoja, C.2
Campana, M.3
Corna, D.4
Sangalli, F.5
Rottoli, D.6
Gagliardini, E.7
Conti, S.8
Ledbetter, S.9
Remuzzi, G.10
-
40
-
-
79956011495
-
A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis
-
Trachtman, H.; Fervenza, F.C.; Gipson, D.S.; Heering, P.; Jayne, D.R.; Peters, H.; Rota, S.; Remuzzi, G.; Rump, L.C.; Sellin, L.K.; Heaton, J.P.; Streisand, J.B.; Hard, M.L.; Ledbetter, S.R.; Vincenti, F. A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis. Kidney Int., 2011, 79, 1236-1243.
-
(2011)
Kidney Int.
, vol.79
, pp. 1236-1243
-
-
Trachtman, H.1
Fervenza, F.C.2
Gipson, D.S.3
Heering, P.4
Jayne, D.R.5
Peters, H.6
Rota, S.7
Remuzzi, G.8
Rump, L.C.9
Sellin, L.K.10
Heaton, J.P.11
Streisand, J.B.12
Hard, M.L.13
Ledbetter, S.R.14
Vincenti, F.15
-
41
-
-
0022846898
-
Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies. A sequential histological and ultrastructural study in the rat
-
Bagchus, W.M.; Hoedemaeker, P.J.; Rozing, J.; Bakker, W.W. Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies. A sequential histological and ultrastructural study in the rat. Lab Invest., 1986, 55, 680-687.
-
(1986)
Lab Invest.
, vol.55
, pp. 680-687
-
-
Bagchus, W.M.1
Hoedemaeker, P.J.2
Rozing, J.3
Bakker, W.W.4
-
42
-
-
0025277164
-
Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1
-
Border, W.A.; Okuda, S.; Languino, L.R.; Sporn, M.B.; Ruoslahti, E. Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1. Nature, 1990, 346, 371-374.
-
(1990)
Nature
, vol.346
, pp. 371-374
-
-
Border, W.A.1
Okuda, S.2
Languino, L.R.3
Sporn, M.B.4
Ruoslahti, E.5
-
43
-
-
0025102712
-
Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix
-
Okuda, S.; Languino, L.R.; Ruoslahti, E.; Border, W.A. Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix. J. Clin. Invest., 1990, 86, 453-462.
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 453-462
-
-
Okuda, S.1
Languino, L.R.2
Ruoslahti, E.3
Border, W.A.4
-
44
-
-
0028280073
-
Sustained expression of TGF-beta 1 underlies development of progressive kidney fibrosis
-
Yamamoto, T.; Noble, N.A.; Miller, D.E.; Border, W.A. Sustained expression of TGF-beta 1 underlies development of progressive kidney fibrosis. Kidney Int., 1994, 45, 916-927.
-
(1994)
Kidney Int.
, vol.45
, pp. 916-927
-
-
Yamamoto, T.1
Noble, N.A.2
Miller, D.E.3
Border, W.A.4
-
45
-
-
10144227768
-
Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis
-
Akagi, Y.; Isaka, Y.; Arai, M.; Kaneko, T.; Takenaka, M.; Moriyama, T.; Kaneda, Y.; Ando, A.; Orita, Y.; Kamada, T.; Ueda, N.; Imai, E. Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int., 1996, 50, 148-155.
-
(1996)
Kidney Int.
, vol.50
, pp. 148-155
-
-
Akagi, Y.1
Isaka, Y.2
Arai, M.3
Kaneko, T.4
Takenaka, M.5
Moriyama, T.6
Kaneda, Y.7
Ando, A.8
Orita, Y.9
Kamada, T.10
Ueda, N.11
Imai, E.12
-
46
-
-
3042795227
-
Effect of antisense TGF-beta1 oligodeoxynucleotides in streptozotocin-induced diabetic rat kidney
-
Jeong, H.S.; Park, K.K.; Park, K.K.; Kim, S.P.; Choi, I.J.; Lee, I.K.; Kim, H.C. Effect of antisense TGF-beta1 oligodeoxynucleotides in streptozotocin-induced diabetic rat kidney. J. Korean Med. Sci., 2004, 19, 374-383.
-
(2004)
J. Korean Med. Sci.
, vol.19
, pp. 374-383
-
-
Jeong, H.S.1
Park, K.K.2
Park, K.K.3
Kim, S.P.4
Choi, I.J.5
Lee, I.K.6
Kim, H.C.7
-
47
-
-
21744440388
-
Delivery of plasmid DNA expressing small interference RNA for TGF-beta type II receptor by cationized gelatin to prevent interstitial renal fibrosis
-
Kushibiki, T.; Nagata-Nakajima, N.; Sugai, M.; Shimizu, A.; Tabata, Y. Delivery of plasmid DNA expressing small interference RNA for TGF-beta type II receptor by cationized gelatin to prevent interstitial renal fibrosis. J. Control Release., 2005, 105, 318-331.
-
(2005)
J. Control Release.
, vol.105
, pp. 318-331
-
-
Kushibiki, T.1
Nagata-Nakajima, N.2
Sugai, M.3
Shimizu, A.4
Tabata, Y.5
-
48
-
-
21644463253
-
Heterozygous mice for TGF-betaIIR gene are resistant to the progression of streptozotocin-induced diabetic nephropathy
-
Kim, H.W.; Kim, B.C.; Song, C.Y.; Kim, J.H.; Hong, H.K.; Lee, H.S. Heterozygous mice for TGF-betaIIR gene are resistant to the progression of streptozotocin-induced diabetic nephropathy. Kidney Int., 2004, 66, 1859-1865.
-
(2004)
Kidney Int.
, vol.66
, pp. 1859-1865
-
-
Kim, H.W.1
Kim, B.C.2
Song, C.Y.3
Kim, J.H.4
Hong, H.K.5
Lee, H.S.6
-
49
-
-
54249093297
-
Application of an adenoviral vector encoding soluble transforming growth factor-beta type II receptor to the treatment of diabetic nephropathy in mice
-
Kondo, T.; Takemura, G.; Kosai, K.; Ohno, T.; Takahashi, T.; Esaki, M.; Goto, K.; Maruyama, R.; Murata, I.; Minatoguchi, S.; Fujiwara, T.; Fujiwara, H. Application of an adenoviral vector encoding soluble transforming growth factor-beta type II receptor to the treatment of diabetic nephropathy in mice. Clin. Exp. Pharmacol. Physiol., 2008, 35, 1288-1293.
-
(2008)
Clin. Exp. Pharmacol. Physiol.
, vol.35
, pp. 1288-1293
-
-
Kondo, T.1
Takemura, G.2
Kosai, K.3
Ohno, T.4
Takahashi, T.5
Esaki, M.6
Goto, K.7
Maruyama, R.8
Murata, I.9
Minatoguchi, S.10
Fujiwara, T.11
Fujiwara, H.12
-
50
-
-
0027276765
-
Betaglycan presents ligand to the TGF beta signaling receptor
-
López-Casillas, F.; Wrana, J.L.; Massagué, J. Betaglycan presents ligand to the TGF beta signaling receptor. Cell, 1993, 73, 1435-1444.
-
(1993)
Cell
, vol.73
, pp. 1435-1444
-
-
López-Casillas, F.1
Wrana, J.L.2
Massagué, J.3
-
51
-
-
1542289879
-
The shedding of betaglycan is regulated by pervanadate and mediated by membrane type matrix metalloprotease-1
-
Velasco-Loyden, G.; Arribas, J.; López-Casillas, F. The shedding of betaglycan is regulated by pervanadate and mediated by membrane type matrix metalloprotease-1. J. Biol. Chem., 2004, 279, 7721-7733.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7721-7733
-
-
Velasco-Loyden, G.1
Arribas, J.2
López-Casillas, F.3
-
52
-
-
0035310360
-
Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent
-
Vilchis-Landeros, M.M.; Montiel, J.L.; Mendoza, V.; Mendoza- Hernández, G.; López-Casillas, F. Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent. Biochem. J., 2001, 355(Pt 1), 215-222.
-
(2001)
Biochem. J.
, vol.355
, Issue.PART 1
, pp. 215-222
-
-
Vilchis-Landeros, M.M.1
Montiel, J.L.2
Mendoza, V.3
Mendoza-Hernández, G.4
López-Casillas, F.5
-
53
-
-
33846187695
-
Soluble betaglycan reduces renal damage progression in db/db mice
-
Juárez, P.; Vilchis-Landeros, M.M.; Ponce-Coria, J.; Mendoza, V, Hernández-Pando R, Bobadilla NA, López-Casillas F. Soluble betaglycan reduces renal damage progression in db/db mice. Am. J. Physiol. Renal. Physiol., 2007, 292, F321-F329.
-
(2007)
Am. J. Physiol. Renal. Physiol.
, vol.292
-
-
Juárez, P.1
Vilchis-Landeros, M.M.2
Ponce-Coria, J.3
Mendoza, V.4
Hernández-Pando, R.5
Bobadilla, N.A.6
López-Casillas, F.7
-
54
-
-
0035070420
-
Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy
-
Mizuno, S.; Matsumoto, K.; Nakamura, T. Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy. Kidney Int., 2001, 59, 1304-1314.
-
(2001)
Kidney Int.
, vol.59
, pp. 1304-1314
-
-
Mizuno, S.1
Matsumoto, K.2
Nakamura, T.3
-
55
-
-
0034782480
-
Systemic administration of naked plasmid encoding hepatocyte growth factor ameliorates chronic renal fibrosis in mice
-
Yang, J.; Dai, C.; Liu, Y. Systemic administration of naked plasmid encoding hepatocyte growth factor ameliorates chronic renal fibrosis in mice. Gene Ther., 2001, 8, 1470-1479.
-
(2001)
Gene Ther.
, vol.8
, pp. 1470-1479
-
-
Yang, J.1
Dai, C.2
Liu, Y.3
-
56
-
-
34248352591
-
Activation of the renin-angiotensin system within podocytes in diabetes
-
Yoo, T.H.; Li, J.J.; Kim, J.J.; Jung, D.S.; Kwak, S.J.; Ryu, D.R.; Choi, H.Y.; Kim, J.S.; Kim, H.J.; Han, S.H.; Lee, J.E.; Han, D.S.; Kang. S.W. Activation of the renin-angiotensin system within podocytes in diabetes. Kidney Int., 2007, 71, 1019-1027.
-
(2007)
Kidney Int.
, vol.71
, pp. 1019-1027
-
-
Yoo, T.H.1
Li, J.J.2
Kim, J.J.3
Jung, D.S.4
Kwak, S.J.5
Ryu, D.R.6
Choi, H.Y.7
Kim, J.S.8
Kim, H.J.9
Han, S.H.10
Lee, J.E.11
Han, D.S.12
Kang, S.W.13
-
57
-
-
84856718373
-
Kidney-targeting Smad7 gene transfer inhibits renal TGF-β/MAD homologue (SMAD) and nuclear factor κb (NF-κB) signalling pathways, and improves diabetic nephropathy in mice
-
Ka, S.M.; Yeh, Y.C.; Huang, X.R.; Chao, T.K.; Hung, Y.J.; Yu, C.P.; Lin, T.J.; Wu, C.C.; Lan, H.Y.; Chen, A. Kidney-targeting Smad7 gene transfer inhibits renal TGF-β/MAD homologue (SMAD) and nuclear factor κB (NF-κB) signalling pathways, and improves diabetic nephropathy in mice. Diabetologia, 2012, 55, 509-519.
-
(2012)
Diabetologia
, vol.55
, pp. 509-519
-
-
Ka, S.M.1
Yeh, Y.C.2
Huang, X.R.3
Chao, T.K.4
Hung, Y.J.5
Yu, C.P.6
Lin, T.J.7
Wu, C.C.8
Lan, H.Y.9
Chen, A.10
-
58
-
-
80053052721
-
Podocytopathy in diabetes: A metabolic and endocrine disorder
-
Diez-Sampedro, A.; Lenz, O.; Fornoni, A. Podocytopathy in diabetes: a metabolic and endocrine disorder. Am. J. Kidney Dis., 2011, 58, 637-646.
-
(2011)
Am. J. Kidney Dis.
, vol.58
, pp. 637-646
-
-
Diez-Sampedro, A.1
Lenz, O.2
Fornoni, A.3
-
59
-
-
84925935926
-
Pathogenesis and progression of proteinuria
-
Thomas, M.C. Pathogenesis and progression of proteinuria. Contrib. Nephrol., 2011, 170, 48-56.
-
(2011)
Contrib. Nephrol.
, vol.170
, pp. 48-56
-
-
Thomas, M.C.1
-
60
-
-
33644783770
-
Glucoseinduced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
-
Susztak, K.; Raff, A.C.; Schiffer, M.; Böttinger, E.P. Glucoseinduced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes, 2006, 55, 225-233.
-
(2006)
Diabetes
, vol.55
, pp. 225-233
-
-
Susztak, K.1
Raff, A.C.2
Schiffer, M.3
Böttinger, E.P.4
-
61
-
-
33645733358
-
Pathogenesis of nonimmune glomerulopathies
-
Kwoh, C.; Shannon, M.B.; Miner, J.H.; Shaw, A. Pathogenesis of nonimmune glomerulopathies. Annu. Rev. Pathol., 2006, 1, 349-374.
-
(2006)
Annu. Rev. Pathol.
, vol.1
, pp. 349-374
-
-
Kwoh, C.1
Shannon, M.B.2
Miner, J.H.3
Shaw, A.4
-
62
-
-
20044362239
-
From the periphery of the glomerular capillary wall toward the center of disease: Podocyte injury comes of age in diabetic nephropathy
-
Wolf, G.; Chen, S.; Ziyadeh, F.N. From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes, 2005, 54, 1626-1634.
-
(2005)
Diabetes
, vol.54
, pp. 1626-1634
-
-
Wolf, G.1
Chen, S.2
Ziyadeh, F.N.3
-
63
-
-
0036789207
-
Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody
-
Flyvbjerg, A.; Dagnaes-Hansen, F.; De Vriese, A.S.; Schrijvers, B.F.; Tilton, R.G.; Rasch, R. Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody. Diabetes, 2002, 51, 3090-3094.
-
(2002)
Diabetes
, vol.51
, pp. 3090-3094
-
-
Flyvbjerg, A.1
Dagnaes-Hansen, F.2
De Vriese, A.S.3
Schrijvers, B.F.4
Tilton, R.G.5
Rasch, R.6
-
64
-
-
84455208254
-
The podocyte as a target for therapies - New and old
-
Mathieson, P.M. The podocyte as a target for therapies - new and old. Nat. Rev. Nephrol., 2011, 8, 53-56.
-
(2011)
Nat. Rev. Nephrol.
, vol.8
, pp. 53-56
-
-
Mathieson, P.M.1
-
65
-
-
79952753333
-
Podocytes as a target of prorenin in diabetes
-
Sakoda, M.; Itoh, H.; Ichihara, A. Podocytes as a target of prorenin in diabetes. Curr. Diabetes Rev., 2011, 7, 17-21.
-
(2011)
Curr. Diabetes Rev.
, vol.7
, pp. 17-21
-
-
Sakoda, M.1
Itoh, H.2
Ichihara, A.3
-
66
-
-
37349120735
-
The podocyte and diabetes mellitus: Is the podocyte the key to the origins of diabetic nephropathy?
-
Reddy, G.R.; Kotlyarevska, K.; Ransom, R.F.; Menon, .RK. The podocyte and diabetes mellitus: is the podocyte the key to the origins of diabetic nephropathy? Curr. Opin. Nephrol. Hypertens., 2008, 17, 32-36.
-
(2008)
Curr. Opin. Nephrol. Hypertens.
, vol.17
, pp. 32-36
-
-
Reddy, G.R.1
Kotlyarevska, K.2
Ransom, R.F.3
Menon, R.K.4
-
67
-
-
68949213587
-
Genetics of nephritic syndrome: New insights into molecules acting at the glomerular filtration barrier
-
Zenker, M.; Machuca, E.; Antignac, C. Genetics of nephritic syndrome: new insights into molecules acting at the glomerular filtration barrier. J. Mol. Med., 2009, 87, 849-857.
-
(2009)
J. Mol. Med.
, vol.87
, pp. 849-857
-
-
Zenker, M.1
Machuca, E.2
Antignac, C.3
-
68
-
-
75749101016
-
Nephrin-signature molecule of the glomerular podocyte?
-
Welsh, G.I.; Saleem, M.A. Nephrin-signature molecule of the glomerular podocyte? Pathol., 2010, 220, 328-337.
-
(2010)
Pathol.
, vol.220
, pp. 328-337
-
-
Welsh, G.I.1
Saleem, M.A.2
-
69
-
-
34547616609
-
Differential expression of nephrin according to glomerular size in early diabetic kidney disease
-
Kim, J.J.; Li, J.J.; Jung, D.S.; Kwak, S.J.; Ryu, D.R.; Yoo, T.H.; Han, S.H.; Choi, H.Y.; Kim, H.J.; Han, D.S.; Kang, S.W. Differential expression of nephrin according to glomerular size in early diabetic kidney disease. J. Am. Soc. Nephrol., 2007, 18, 2303-2310.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 2303-2310
-
-
Kim, J.J.1
Li, J.J.2
Jung, D.S.3
Kwak, S.J.4
Ryu, D.R.5
Yoo, T.H.6
Han, S.H.7
Choi, H.Y.8
Kim, H.J.9
Han, D.S.10
Kang, S.W.11
-
70
-
-
0041842626
-
Expression of podocyte-associated molecules in acquired human kidney diseases
-
Koop, K.; Eikmans, M.; Baelde, H.J.; Kawachi, H.; De Heer, E.; Paul, L.C.; Bruijn, J.A. Expression of podocyte-associated molecules in acquired human kidney diseases. J. Am. Soc. Nephrol., 2003, 14, 2063-2071.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 2063-2071
-
-
Koop, K.1
Eikmans, M.2
Baelde, H.J.3
Kawachi, H.4
De Heer, E.5
Paul, L.C.6
Bruijn, J.A.7
-
71
-
-
0345505674
-
Nephrin expression is reduced in human diabetic nephropathy: Evidence for a distinct role for glycated albumin and angiotensin II
-
Doublier, S.; Salvidio, G.; Lupia, E.; Ruotsalainen, V.; Verzola, D.; Deferrari, G.; Camussi, G. Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II. Diabetes, 2003, 52, 1023-1030.
-
(2003)
Diabetes
, vol.52
, pp. 1023-1030
-
-
Doublier, S.1
Salvidio, G.2
Lupia, E.3
Ruotsalainen, V.4
Verzola, D.5
Deferrari, G.6
Camussi, G.7
-
72
-
-
77956302476
-
Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis
-
e10185
-
Tossidou, I.; Teng, B.; Menne, J.; Shushakova, N.; Park, J.K.; Becker, J.U.; Modde, F.; Leitges, M.; Haller, H.; Schiffer, M. Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis. PLoS One, 2010, 5: e10185.
-
(2010)
PLoS One
, vol.5
-
-
Tossidou, I.1
Teng, B.2
Menne, J.3
Shushakova, N.4
Park, J.K.5
Becker, J.U.6
Modde, F.7
Leitges, M.8
Haller, H.9
Schiffer, M.10
-
73
-
-
79953840843
-
PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia
-
Quack, I.; Woznowski, M.; Potthoff, S.A.; Palmer, R.; Königshausen, E.; Sivritas, S.; Schiffer, M.; Stegbauer, J.; Vonend. O.; Rump, L.C.; Sellin, L. PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia. J. Biol. Chem., 2011, 286, 12959-12970.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12959-12970
-
-
Quack, I.1
Woznowski, M.2
Potthoff, S.A.3
Palmer, R.4
Königshausen, E.5
Sivritas, S.6
Schiffer, M.7
Stegbauer, J.8
Vonend., O.9
Rump, L.C.10
Sellin, L.11
-
74
-
-
33749515477
-
Nephrin loss in experimental diabetic nephropathy is preventedby deletion of protein kinase C alpha signaling in-vivo
-
Menne, J.; Meier, M.; Park, J.K.; Boehne, M.; Kirsch, T.; Lindschau, C.; Ociepka, R.; Leitges, M.; Rinta-Valkama, J.; Holthofer, H.; Haller, H. Nephrin loss in experimental diabetic nephropathy is preventedby deletion of protein kinase C alpha signaling in-vivo. Kidney Int., 2006, 70, 1456-1462.
-
(2006)
Kidney Int.
, vol.70
, pp. 1456-1462
-
-
Menne, J.1
Meier, M.2
Park, J.K.3
Boehne, M.4
Kirsch, T.5
Lindschau, C.6
Ociepka, R.7
Leitges, M.8
Rinta-Valkama, J.9
Holthofer, H.10
Haller, H.11
-
75
-
-
0035008793
-
Glomerular cell number in normal subjects and in type 1 diabetic patients
-
Steffes, M.W.; Schmidt, D.; McCrery, R.; Basgen, J.M. Glomerular cell number in normal subjects and in type 1 diabetic patients. Kidney Int., 2001, 59, 2104-2113.
-
(2001)
Kidney Int.
, vol.59
, pp. 2104-2113
-
-
Steffes, M.W.1
Schmidt, D.2
McCrery, R.3
Basgen, J.M.4
-
76
-
-
34948906839
-
Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor
-
Chuang, P.Y.; Yu, Q.; Fang, W.; Uribarri, J.; He, J.C. Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor. Kidney Int., 2007, 72, 965-976.
-
(2007)
Kidney Int.
, vol.72
, pp. 965-976
-
-
Chuang, P.Y.1
Yu, Q.2
Fang, W.3
Uribarri, J.4
He, J.C.5
-
77
-
-
40449112321
-
The Notch pathway in podocytes plays a role in the development of glomerular disease
-
Niranjan, T.; Bielesz, B.; Gruenwald, A.; Ponda, M.P.; Kopp, J.B.; Thomas, D.B.; Susztak, K. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat. Med., 2008, 14, 290-298.
-
(2008)
Nat. Med.
, vol.14
, pp. 290-298
-
-
Niranjan, T.1
Bielesz, B.2
Gruenwald, A.3
Ponda, M.P.4
Kopp, J.B.5
Thomas, D.B.6
Susztak, K.7
-
78
-
-
0037377697
-
RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy
-
Wendt, T.M.; Tanji, N.; Guo, J.; Kislinger, T.R.; Qu, W.; Lu, Y.; Bucciarelli, LG, Rong LL, Moser B, Markowitz GS, Stein G, Bierhaus A, Liliensiek B, Arnold B, Nawroth, P.P.; Stern, D.M.; D'Agati, V.D.; Schmidt, A.M. RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. Am. J. Pathol., 2003, 162, 1123-1137.
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1123-1137
-
-
Wendt, T.M.1
Tanji, N.2
Guo, J.3
Kislinger, T.R.4
Qu, W.5
Lu, Y.6
Bucciarelli, L.G.7
Rong, L.L.8
Moser, B.9
Markowitz, G.S.10
Stein, G.11
Bierhaus, A.12
Liliensiek, B.13
Arnold, B.14
Nawroth, P.P.15
Stern, D.M.16
D'Agati, V.D.17
Schmidt, A.M.18
-
79
-
-
33750590947
-
RAGE control of diabetic nephropathy in a mouse model: Effects of RAGE gene disruption and administration of low-molecular weight heparin
-
Myint, K.M.; Yamamoto, Y.; Doi, T.; Kato, I.; Harashima, A.; Yonekur,a H.; Watanabe, T.; Shinohara, H.; Takeuchi, M.; Tsuneyama, K.; Hashimoto, N.; Asano, M.; Takasawa, S.; Okamoto, H.; Yamamoto, H. RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin. Diabetes, 2006, 55, 2510-2522.
-
(2006)
Diabetes
, vol.55
, pp. 2510-2522
-
-
Myint, K.M.1
Yamamoto, Y.2
Doi, T.3
Kato, I.4
Harashima, A.5
Yonekura, H.6
Watanabe, T.7
Shinohara, H.8
Takeuchi, M.9
Tsuneyama, K.10
Hashimoto, N.11
Asano, M.12
Takasawa, S.13
Okamoto, H.14
Yamamoto, H.15
-
80
-
-
36749101547
-
Bone morphogenetic protein-7 delays podocyte injury due to high glucose
-
De Petris, L.; Hruska, K.A.; Chiechio, S.; Liapis, H. Bone morphogenetic protein-7 delays podocyte injury due to high glucose. Nephrol. Dial. Transplant., 2007, 22, 3442-3450.
-
(2007)
Nephrol. Dial. Transplant.
, vol.22
, pp. 3442-3450
-
-
De Petris, L.1
Hruska, K.A.2
Chiechio, S.3
Liapis, H.4
-
81
-
-
36049022526
-
BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury
-
Mitu, G.M.; Wang, S.; Hirschberg, R. BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury. Am. J. Physiol. Renal. Physiol., 2007, 293, F1641-F1648.
-
(2007)
Am. J. Physiol. Renal. Physiol.
, vol.293
-
-
Mitu, G.M.1
Wang, S.2
Hirschberg, R.3
-
82
-
-
0037648482
-
Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy
-
Wang, S.; Chen, Q.; Simon, T.C.; Strebeck, F.; Chaudhary, L.; Morrissey, J.; Liapis, H.; Klahr, S.; Hruska, K.A. Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy. Kidney Int., 2003, 63, 2037-2049.
-
(2003)
Kidney Int.
, vol.63
, pp. 2037-2049
-
-
Wang, S.1
Chen, Q.2
Simon, T.C.3
Strebeck, F.4
Chaudhary, L.5
Morrissey, J.6
Liapis, H.7
Klahr, S.8
Hruska, K.A.9
-
83
-
-
33748062324
-
Renal bone morphogenetic protein-7 protects against diabetic nephropathy
-
Wang, S.; de Caestecker, M.; Kopp, J.; Mitu, G.; Lapage, J.; Hirschberg, R. Renal bone morphogenetic protein-7 protects against diabetic nephropathy. J. Am. Soc. Nephrol., 2006, 17, 2504-2512.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 2504-2512
-
-
Wang, S.1
De Caestecker, M.2
Kopp, J.3
Mitu, G.4
Lapage, J.5
Hirschberg, R.6
-
84
-
-
0031959237
-
Expression of connective tissue growth factor in human renal fibrosis
-
Ito, Y.; Aten, J.; Bende, R.J.; Oemar, B.S.; Rabelink, T.J.; Weening, J.J.; Goldschmeding, R. Expression of connective tissue growth factor in human renal fibrosis. Kidney Int., 1998, 53, 853-861.
-
(1998)
Kidney Int.
, vol.53
, pp. 853-861
-
-
Ito, Y.1
Aten, J.2
Bende, R.J.3
Oemar, B.S.4
Rabelink, T.J.5
Weening, J.J.6
Goldschmeding, R.7
-
85
-
-
0033957976
-
Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
-
Riser, B.L.; Denichilo, M.; Cortes, P.; Baker, C.; Grondin, J.M.; Yee, J.; Narins, R.G. Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis. J. Am. Soc. Nephrol., 2000, 11, 25-38.
-
(2000)
J. Am. Soc. Nephrol.
, vol.11
, pp. 25-38
-
-
Riser, B.L.1
Denichilo, M.2
Cortes, P.3
Baker, C.4
Grondin, J.M.5
Yee, J.6
Narins, R.G.7
-
86
-
-
33644875787
-
Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy
-
Nguyen, T.Q.; Tarnow, L.; Andersen, S.; Hovind, P.; Parving. H.H.; Goldschmeding, R.; van Nieuwenhoven, F.A. Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy. Diabetes Care, 2006, 29, 83-86.
-
(2006)
Diabetes Care
, vol.29
, pp. 83-86
-
-
Nguyen, T.Q.1
Tarnow, L.2
Andersen, S.3
Hovind, P.4
Parving, H.H.5
Goldschmeding, R.6
Van Nieuwenhoven, F.A.7
-
87
-
-
48649102468
-
Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy
-
Nguyen, T.Q.; Tarnow, L.; Jorsal, A.; Oliver, N.; Roestenberg, P.; Ito, Y.; Parving, H.H.; Rossing, P.; van Nieuwenhoven, F.A.; Goldschmeding, R. Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy. Diabetes Care, 2008, 31, 1177-1182.
-
(2008)
Diabetes Care
, vol.31
, pp. 1177-1182
-
-
Nguyen, T.Q.1
Tarnow, L.2
Jorsal, A.3
Oliver, N.4
Roestenberg, P.5
Ito, Y.6
Parving, H.H.7
Rossing, P.8
Van Nieuwenhoven, F.A.9
Goldschmeding, R.10
-
88
-
-
55749104230
-
CTGF inhibits BMP-7 signaling in diabetic nephropathy
-
Nguyen, T.Q.; Roestenberg, P.; van Nieuwenhoven, F.A.; Bovenschen, N.; Li, Z.; Xu, L.; Oliver, N.; Aten, J.; Joles, J.A.; Vial, C.; Brandan, E.; Lyons, K.M.; Goldschmeding, R. CTGF inhibits BMP-7 signaling in diabetic nephropathy. J. Am. Soc. Nephrol., 2008, 19, 2098-2107.
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 2098-2107
-
-
Nguyen, T.Q.1
Roestenberg, P.2
Van Nieuwenhoven, F.A.3
Bovenschen, N.4
Li, Z.5
Xu, L.6
Oliver, N.7
Aten, J.8
Joles, J.A.9
Vial, C.10
Brandan, E.11
Lyons, K.M.12
Goldschmeding, R.13
-
89
-
-
35248841125
-
Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes
-
Guha, M.; Xu, Z.G.; Tung, D.; Lanting, L.; Natarajan, R. Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes. FASEB J., 2007, 21, 3355-3368.
-
(2007)
FASEB J.
, vol.21
, pp. 3355-3368
-
-
Guha, M.1
Xu, Z.G.2
Tung, D.3
Lanting, L.4
Natarajan, R.5
-
90
-
-
44949105469
-
Activation of a local renin angiotensin system in podocytes by glucose
-
Durvasula, R.V.; Shankland, S.J. Activation of a local renin angiotensin system in podocytes by glucose. Am. J. Physiol. Renal. Physiol., 2008, 294, F830-F839.
-
(2008)
Am. J. Physiol. Renal. Physiol.
, vol.294
-
-
Durvasula, R.V.1
Shankland, S.J.2
-
91
-
-
0037207471
-
Cell biology of the glomerular podocyte
-
Pavenstädt, H.; Kriz, W.; Kretzler, M. Cell biology of the glomerular podocyte. Physiol. Rev., 2003, 83, 253-307.
-
(2003)
Physiol. Rev.
, vol.83
, pp. 253-307
-
-
Pavenstädt, H.1
Kriz, W.2
Kretzler, M.3
-
92
-
-
0036089691
-
Angiotensin II induces apoptosis in rat glomerular epithelial cells
-
Ding, G.; Reddy, K.; Kapasi, A.A.; Franki, N.; Gibbons, N.; Kasinath, B.S.; Singhal, P.C. Angiotensin II induces apoptosis in rat glomerular epithelial cells. Am. J. Physiol. Renal. Physiol., 2002, 283, F173-F180.
-
(2002)
Am. J. Physiol. Renal. Physiol.
, vol.283
-
-
Ding, G.1
Reddy, K.2
Kapasi, A.A.3
Franki, N.4
Gibbons, N.5
Kasinath, B.S.6
Singhal, P.C.7
-
93
-
-
2542455650
-
Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats
-
Hoffmann, S.; Podlich, D.; Hähnel, B.; Kriz, W.; Gretz, N. Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats. J. Am. Soc. Nephrol., 2004, 15, 1475-1487.
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 1475-1487
-
-
Hoffmann, S.1
Podlich, D.2
Hähnel, B.3
Kriz, W.4
Gretz, N.5
-
94
-
-
0034945789
-
Podocyte foot process broadening in experimental diabetic nephropathy: Amelioration with renin-angiotensin blockade
-
Mifsud, S.A.; Allen, T.J.; Bertram, J.F.; Hulthen, U.L.; Kelly, D.J.; Cooper, M.E.; Wilkinson-Berka, J.L.; Gilbert, R.E. Podocyte foot process broadening in experimental diabetic nephropathy: amelioration with renin-angiotensin blockade. Diabetologia, 2001, 44, 878-882.
-
(2001)
Diabetologia
, vol.44
, pp. 878-882
-
-
Mifsud, S.A.1
Allen, T.J.2
Bertram, J.F.3
Hulthen, U.L.4
Kelly, D.J.5
Cooper, M.E.6
Wilkinson-Berka, J.L.7
Gilbert, R.E.8
-
95
-
-
0036020933
-
Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: Differing effects of anti-proteinuric therapies
-
Kelly, D.J.; Aaltonen, P.; Cox, A.J.; Rumble, J.R.; Langham, R.; Panagiotopoulos, S.; Jerums, G.; Holthöfer, H.; Gilbert, R.E. Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies. Nephrol. Dial. Transplant., 2002, 17, 1327-1332.
-
(2002)
Nephrol. Dial. Transplant.
, vol.17
, pp. 1327-1332
-
-
Kelly, D.J.1
Aaltonen, P.2
Cox, A.J.3
Rumble, J.R.4
Langham, R.5
Panagiotopoulos, S.6
Jerums, G.7
Holthöfer, H.8
Gilbert, R.E.9
-
96
-
-
84857784989
-
Angiotensinconverting enzyme 2: Enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy
-
Batlle, D.; Wysocki, J.; Soler, M.J.; Ranganath, K. Angiotensinconverting enzyme 2: enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy. Kidney Int., 2012, 81, 520-528.
-
(2012)
Kidney Int.
, vol.81
, pp. 520-528
-
-
Batlle, D.1
Wysocki, J.2
Soler, M.J.3
Ranganath, K.4
-
97
-
-
0038053724
-
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin i to angiotensin 1-9
-
Donoghue, M.; Hsieh, F.; Baronas, E.; Godbout, K.; Gosselin, M.; Stagliano, N.; Donovan, M.; Woolf, B.; Robison, K.; Jeyaseelan, R.; Breitbart, R.E.; Acton, S. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res., 2000, 87, E1-E9.
-
(2000)
Circ Res.
, vol.87
-
-
Donoghue, M.1
Hsieh, F.2
Baronas, E.3
Godbout, K.4
Gosselin, M.5
Stagliano, N.6
Donovan, M.7
Woolf, B.8
Robison, K.9
Jeyaseelan, R.10
Breitbart, R.E.11
Acton, S.12
-
98
-
-
0034721906
-
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
-
Tipnis, S.R.; Hooper, N.M.; Hyde, R.; Karran, E.; Christie, G.; Turne, A.J. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J. Biol. Chem., 2000, 275, 33238-33243.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33238-33243
-
-
Tipnis, S.R.1
Hooper, N.M.2
Hyde, R.3
Karran, E.4
Christie, G.5
Turne, A.J.6
-
99
-
-
77449160523
-
Human recombinant ACE2 reduces the progression of diabetic nephropathy
-
Oudit, G.Y.; Liu, G.C.; Zhong, J.; Basu, R.; Chow, F.L.; Zhou, J.; Loibner, H.; Janzek, E.; Schuster, M.; Penninger, J.M.; Herzenberg, A.M.; Kassiri, Z.; Scholey, J.W. Human recombinant ACE2 reduces the progression of diabetic nephropathy. Diabetes, 2010, 59, 529-538.
-
(2010)
Diabetes
, vol.59
, pp. 529-538
-
-
Oudit, G.Y.1
Liu, G.C.2
Zhong, J.3
Basu, R.4
Chow, F.L.5
Zhou, J.6
Loibner, H.7
Janzek, E.8
Schuster, M.9
Penninger, J.M.10
Herzenberg, A.M.11
Kassiri, Z.12
Scholey, J.W.13
-
100
-
-
78651497653
-
Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: A comparison with ACE inhibition
-
Liu, C.X.; Hu, Q.; Wang, Y.; Zhang, W.; Ma, Z.Y.; Feng, J.B.; Wang, R.; Wang, X.P.; Dong, B.; Gao, F.; Zhang, M.X.; Zhang, Y. Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: a comparison with ACE inhibition. Mol. Med., 2011, 17, 59-69.
-
(2011)
Mol. Med.
, vol.17
, pp. 59-69
-
-
Liu, C.X.1
Hu, Q.2
Wang, Y.3
Zhang, W.4
Ma, Z.Y.5
Feng, J.B.6
Wang, R.7
Wang, X.P.8
Dong, B.9
Gao, F.10
Zhang, M.X.11
Zhang, Y.12
-
101
-
-
33744731510
-
Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis
-
Oudit, G.Y.; Herzenberg, A.M.; Kassiri, Z.; Wong, D.; Reich, H.; Khokha, R.; Crackower, M.A.; Backx, P.H.; Penninger, J,M,; Scholey, J.W. Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis. Am. J. Pathol., 2006, 168, 1808-1820.
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 1808-1820
-
-
Oudit, G.Y.1
Herzenberg, A.M.2
Kassiri, Z.3
Wong, D.4
Reich, H.5
Khokha, R.6
Crackower, M.A.7
Backx, P.H.8
Penninger, J.M.9
Scholey, J.W.10
-
102
-
-
34548295365
-
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
-
Wong, D.W.; Oudit, G.Y.; Reich, H.; Kassiri, Z.; Zhou, J.; Liu, Q.C.; Backx, P.H.; Penninger, J.M.; Herzenberg, A.M.; Scholey, J.W. Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. Am. J. Pathol., 2007, 171, 438-451.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 438-451
-
-
Wong, D.W.1
Oudit, G.Y.2
Reich, H.3
Kassiri, Z.4
Zhou, J.5
Liu, Q.C.6
Backx, P.H.7
Penninger, J.M.8
Herzenberg, A.M.9
Scholey, J.W.10
-
103
-
-
33750722109
-
Glomerular localization and expression of Angiotensin-converting enzyme 2 and Angiotensin-converting enzyme: Implications for albuminuria in diabetes
-
Ye, M.; Wysocki, J.; William, J.; Soler, M.J.; Cokic, I.; Batlle, D. Glomerular localization and expression of Angiotensin-converting enzyme 2 and Angiotensin-converting enzyme: implications for albuminuria in diabetes. J. Am. Soc. Nephrol., 2006, 17, 3067-3075.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 3067-3075
-
-
Ye, M.1
Wysocki, J.2
William, J.3
Soler, M.J.4
Cokic, I.5
Batlle, D.6
-
104
-
-
84863802059
-
Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice
-
Nadarajah, R.; Milagres, R.; Dilauro, M.; Gutsol, A.; Xiao, F.; Zimpelmann, J.; Kennedy, C.; Wysocki, J.; Batlle, D.; Burns, K.D. Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice. Kidney Int., 2012, 82, 292-303.
-
(2012)
Kidney Int.
, vol.82
, pp. 292-303
-
-
Nadarajah, R.1
Milagres, R.2
Dilauro, M.3
Gutsol, A.4
Xiao, F.5
Zimpelmann, J.6
Kennedy, C.7
Wysocki, J.8
Batlle, D.9
Burns, K.D.10
-
105
-
-
84863809699
-
Podocyte ACE2 protects against diabetic nephropathy
-
Harris, R.C. Podocyte ACE2 protects against diabetic nephropathy. Kidney Int., 2012, 82, 255-256.
-
(2012)
Kidney Int.
, vol.82
, pp. 255-256
-
-
Harris, R.C.1
-
106
-
-
57049086924
-
Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease
-
Reich, H.N.; Oudit, G.Y.; Penninger, J.M.; Scholey, J.W.; Herzenberg, A.M. Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease. Kidney Int., 2008, 74, 1610-1616.
-
(2008)
Kidney Int.
, vol.74
, pp. 1610-1616
-
-
Reich, H.N.1
Oudit, G.Y.2
Penninger, J.M.3
Scholey, J.W.4
Herzenberg, A.M.5
-
107
-
-
33846857348
-
Statinsensitive endocytosis of albumin by glomerular podocytes
-
Eyre, J.; Ioannou, K.; Grubb, B.D.; Saleem, M.A.; Mathieson, P.W.; Brunskill, N.J.; Christensen, E.I.; Topham, P.S. Statinsensitive endocytosis of albumin by glomerular podocytes. Am. J. Physiol. Renal Physiol., 2007, 292, F674-F681.
-
(2007)
Am. J. Physiol. Renal Physiol.
, vol.292
-
-
Eyre, J.1
Ioannou, K.2
Grubb, B.D.3
Saleem, M.A.4
Mathieson, P.W.5
Brunskill, N.J.6
Christensen, E.I.7
Topham, P.S.8
-
108
-
-
38949210805
-
Podocytes use FcRn to clear IgG from the glomerular basement membrane
-
Akilesh, S.; Huber, T.B.; Wu, H.; Wang, G.; Hartleben, B.; Kopp, J.B.; Miner, J.H.; Roopenian, D.C.; Unanue, E.R.; Shaw, A.S. Podocytes use FcRn to clear IgG from the glomerular basement membrane. Proc. Natl. Acad. Sci. U S A., 2008, 105, 967-972.
-
(2008)
Proc. Natl. Acad. Sci. U S A.
, vol.105
, pp. 967-972
-
-
Akilesh, S.1
Huber, T.B.2
Wu, H.3
Wang, G.4
Hartleben, B.5
Kopp, J.B.6
Miner, J.H.7
Roopenian, D.C.8
Unanue, E.R.9
Shaw, A.S.10
-
109
-
-
77949756180
-
Novel siRNA delivery system to target podocytes in vivo
-
e9463
-
Hauser, P.V.; Pippin, J.W.; Kaiser, C.; Krofft, R.D.; Brinkkoetter, P.T.; Hudkins, K.L.; Kerjaschki, D.; Reiser, J.; Alpers, C.E.; Shankland, S.J. Novel siRNA delivery system to target podocytes in vivo. PLoS One, 2010, 5, e9463.
-
(2010)
PLoS One
, vol.5
-
-
Hauser, P.V.1
Pippin, J.W.2
Kaiser, C.3
Krofft, R.D.4
Brinkkoetter, P.T.5
Hudkins, K.L.6
Kerjaschki, D.7
Reiser, J.8
Alpers, C.E.9
Shankland, S.J.10
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