Neutralization of TGF-β by anti-TGF-β antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice

Diabetes

Volumn 45, Issue 4, 1996, Pages 522-530

  Sharma, Kumar ^b   Jin, Yulin ^a   Guo, Jia ^a   Ziyadeh, Fuad N ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; FIBRONECTIN; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DIABETIC NEPHROPATHY; FEMALE; GLOMERULUS; INTERSTITIUM; KIDNEY PROXIMAL TUBULE; MESANGIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; STREPTOZOCIN DIABETES;

ANIMALS; ANTIBODIES, MONOCLONAL; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DNA, COMPLEMENTARY; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION; HYPERTROPHY; IMMUNOGLOBULIN G; KIDNEY; KIDNEY CORTEX; MICE; MICE, INBRED C57BL; NEUTRALIZATION TESTS; ORGAN SIZE; REFERENCE VALUES; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029924637     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.4.522     Document Type: Article

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