메뉴 건너뛰기




Volumn 82, Issue 3, 2012, Pages 292-303

Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice

Author keywords

ACE2; albuminuria; angiotensin; apoptosis; diabetes; podocyte

Indexed keywords

ALBUMIN; ANGIOTENSIN CONVERTING ENZYME 2; MESSENGER RNA; NEPHRIN; PROTEIN; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84863802059     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2012.83     Document Type: Article
Times cited : (102)

References (39)
  • 1
    • 0038053724 scopus 로고    scopus 로고
    • A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
    • Donoghue M, Hsieh F, Baronas E et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000; 87: e1-e9.
    • (2000) Circ Res , vol.87
    • Donoghue, M.1    Hsieh, F.2    Baronas, E.3
  • 2
    • 0034721906 scopus 로고    scopus 로고
    • A human homolog of angiotensin-converting enzyme
    • Tipnis S, Hooper N, Hyde R et al. A human homolog of angiotensin- converting enzyme. J Biol Chem 2000; 275: 33238-33243.
    • (2000) J Biol Chem , vol.275 , pp. 33238-33243
    • Tipnis, S.1    Hooper, N.2    Hyde, R.3
  • 3
    • 0029957780 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibits vascular smooth muscle cell growth
    • Freeman EJ, Chisolm GM, Ferrario CM et al. Angiotensin-(1-7) inhibits vascular smooth muscle cell growth. Hypertension 1996; 28: 104-108. (Pubitemid 26231097)
    • (1996) Hypertension , vol.28 , Issue.1 , pp. 104-108
    • Freeman, E.J.1    Chisolm, G.M.2    Ferrario, C.M.3    Tallant, E.A.4
  • 4
    • 36448975192 scopus 로고    scopus 로고
    • Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells
    • DOI 10.1161/HYPERTENSIONAHA.106.084848
    • Sampaio WO, Henrique de Castro C, Santos RA et al. Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells. Hypertension 2007; 50: 1093-1098. (Pubitemid 350172931)
    • (2007) Hypertension , vol.50 , Issue.6 , pp. 1093-1098
    • Sampaio, W.O.1    De Castro, C.H.2    Santos, R.A.S.3    Schiffrin, E.L.4    Touyz, R.M.5
  • 5
    • 33745066911 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells
    • DOI 10.1038/sj.ki.5001509, PII 5001509
    • Su Z, Zimpelmann J, Burns KD. Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells. Kidney Int 2006; 69: 2212-2218. (Pubitemid 43882108)
    • (2006) Kidney International , vol.69 , Issue.12 , pp. 2212-2218
    • Su, Z.1    Zimpelmann, J.2    Burns, K.D.3
  • 6
    • 6344246036 scopus 로고    scopus 로고
    • Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism
    • DOI 10.1042/BJ20040634
    • Rice G, Thomas D, Grant P et al. Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. Biochem J 2004; 383: 45-51. (Pubitemid 39389449)
    • (2004) Biochemical Journal , vol.383 , Issue.1 , pp. 45-51
    • Rice, G.I.1    Thomas, D.A.2    Grant, P.J.3    Turner, A.J.4    Hooper, N.M.5
  • 7
    • 2342472108 scopus 로고    scopus 로고
    • Increased ACE 2 and Decreased ACE Protein in Renal Tubules from Diabetic Mice: A Renoprotective Combination?
    • DOI 10.1161/01.HYP.0000126192.27644.76
    • Ye M, Wysocki J, Naaz P et al. Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination? Hypertension 2004; 43: 1120-1125. (Pubitemid 38579924)
    • (2004) Hypertension , vol.43 , Issue.5 , pp. 1120-1125
    • Ye, M.1    Wysocki, J.2    Naaz, P.3    Salabat, M.R.4    LaPointe, M.S.5    Batlle, D.6
  • 8
    • 34548153521 scopus 로고    scopus 로고
    • ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice
    • DOI 10.1038/sj.ki.5002373, PII 5002373
    • Soler M, Wysocki J, Ye M et al. ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice. Kidney Int 2007; 72: 614-623. (Pubitemid 47312795)
    • (2007) Kidney International , vol.72 , Issue.5 , pp. 614-623
    • Soler, M.J.1    Wysocki, J.2    Ye, M.3    Lloveras, J.4    Kanwar, Y.5    Batlle, D.6
  • 10
    • 77449160523 scopus 로고    scopus 로고
    • Human recombinant ACE2 reduces the progression of diabetic nephropathy
    • Oudit G, Liu G, Zhong J et al. Human recombinant ACE2 reduces the progression of diabetic nephropathy. Diabetes 2010; 59: 529-538.
    • (2010) Diabetes , vol.59 , pp. 529-538
    • Oudit, G.1    Liu, G.2    Zhong, J.3
  • 11
    • 78651497653 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: A comparison with ACE inhibition
    • Liu CX, Hu Q, Wang Y et al. Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: a comparison with ACE inhibition. Mol Med 2011; 17: 59-69.
    • (2011) Mol Med , vol.17 , pp. 59-69
    • Liu, C.X.1    Hu, Q.2    Wang, Y.3
  • 12
    • 84857784989 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2: Enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy
    • Batlle D, Wysocki J, Soler MJ et al. Angiotensin-converting enzyme 2: enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy. Kidney Int 2011; 81: 520-528.
    • (2011) Kidney Int , vol.81 , pp. 520-528
    • Batlle, D.1    Wysocki, J.2    Soler, M.J.3
  • 13
  • 14
    • 34547611903 scopus 로고    scopus 로고
    • Podocyte detachment and reduced glomerular capillary endothelial fenestration in human type 1 diabetic nephropathy
    • DOI 10.2337/db07-0019
    • Toyoda M, Najafian B, Kim Y et al. Podocyte detachment and reduced glomerular capillary endothelial fenestration in human type 1 diabetic nephropathy. Diabetes 2007; 56: 2155-2160. (Pubitemid 47195834)
    • (2007) Diabetes , vol.56 , Issue.8 , pp. 2155-2160
    • Toyoda, M.1    Najafian, B.2    Kim, Y.3    Caramori, M.L.4    Mauer, M.5
  • 15
    • 33750722109 scopus 로고    scopus 로고
    • Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: Implications for albuminuria in diabetes
    • DOI 10.1681/ASN.2006050423
    • Ye M, Wysocki J, Soler M et al. Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: implications for albuminuria in diabetes. J Am Soc Nephrol 2006; 17: 3067-3075. (Pubitemid 44707767)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.11 , pp. 3067-3075
    • Ye, M.1    Wysocki, J.2    William, J.3    Soler, M.J.4    Cokic, I.5    Batlle, D.6
  • 16
    • 44949105469 scopus 로고    scopus 로고
    • Activation of a local renin angiotensin system in podocytes by glucose
    • Durvasula RV, Shankland SJ. Activation of a local renin angiotensin system in podocytes by glucose. Am J Physiol Renal Physiol 2008; 294: F830-F839.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Durvasula, R.V.1    Shankland, S.J.2
  • 18
    • 34248352591 scopus 로고    scopus 로고
    • Activation of the renin-angiotensin system within podocytes in diabetes
    • Yoo TH, Li JJ, Kim JJ et al. Activation of the renin-angiotensin system within podocytes in diabetes. Kidney Int 2007; 71: 1019-1027.
    • (2007) Kidney Int , vol.71 , pp. 1019-1027
    • Yoo, T.H.1    Li, J.J.2    Kim, J.J.3
  • 19
    • 79957927211 scopus 로고    scopus 로고
    • MTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
    • Inoki K, Mori H, Wang J et al. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J Clin Invest 2011; 121: 2191-2196.
    • (2011) J Clin Invest , vol.121 , pp. 2191-2196
    • Inoki, K.1    Mori, H.2    Wang, J.3
  • 20
    • 80054772222 scopus 로고    scopus 로고
    • Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis
    • Hsu HH, Hoffmann S, Di Marco GS et al. Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis. Kidney Int 2011; 80: 959-969.
    • (2011) Kidney Int , vol.80 , pp. 959-969
    • Hsu, H.H.1    Hoffmann, S.2    Di Marco, G.S.3
  • 22
    • 57049086924 scopus 로고    scopus 로고
    • Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease
    • Reich HN, Oudit GY, Penninger JM et al. Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease. Kidney Int 2008; 74: 1610-1616.
    • (2008) Kidney Int , vol.74 , pp. 1610-1616
    • Reich, H.N.1    Oudit, G.Y.2    Penninger, J.M.3
  • 24
    • 0035164681 scopus 로고    scopus 로고
    • The murine nephrin gene is specifically expressed in kidney, brain and pancreas: Inactivation of the gene leads to massive proteinuria and neonatal death
    • Putaala H, Soininen R, Kilpeläinen P et al. The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. Hum Mol Genet 2001; 10: 1-8. (Pubitemid 32051561)
    • (2001) Human Molecular Genetics , vol.10 , Issue.1 , pp. 1-8
    • Putaala, H.1    Soininen, R.2    Kilpelainen, P.3    Wartiovaara, J.4    Tryggvason, K.5
  • 26
    • 0345505674 scopus 로고    scopus 로고
    • Nephrin expression is reduced in human diabetic nephropathy: Evidence for a distinct role for glycated albumin and angiotensin II
    • DOI 10.2337/diabetes.52.4.1023
    • Doublier S, Salvidio G, Lupia E et al. Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II. Diabetes 2003; 52: 1023-1030. (Pubitemid 36384273)
    • (2003) Diabetes , vol.52 , Issue.4 , pp. 1023-1030
    • Doublier, S.1    Salvidio, G.2    Lupia, E.3    Ruotsalainen, V.4    Verzola, D.5    Deferrari, G.6    Camussi, G.7
  • 27
    • 68049120573 scopus 로고    scopus 로고
    • Nephrin deficiency activates NF-kappaB and promotes glomerular injury
    • Hussain S, Romio L, Saleem M et al. Nephrin deficiency activates NF-kappaB and promotes glomerular injury. J Am Soc Nephrol 2009; 20: 1733-1740.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1733-1740
    • Hussain, S.1    Romio, L.2    Saleem, M.3
  • 28
    • 24144496134 scopus 로고    scopus 로고
    • Characterization of susceptibility of inbred mouse strains to diabetic nephropathy
    • DOI 10.2337/diabetes.54.9.2628
    • Qi Z, Fujita H, Jin J et al. Characterization of susceptibility of inbred mouse strains to diabetic nephropathy. Diabetes 2005; 54: 2628-2637. (Pubitemid 41233584)
    • (2005) Diabetes , vol.54 , Issue.9 , pp. 2628-2637
    • Qi, Z.1    Fujita, H.2    Jin, J.3    Davis, L.S.4    Wang, Y.5    Fogo, A.B.6    Breyer, M.D.7
  • 29
    • 84555188487 scopus 로고    scopus 로고
    • Heparanase is essential for the development of diabetic nephropathy in mice
    • Gil N, Goldberg R, Neuman T et al. Heparanase is essential for the development of diabetic nephropathy in mice. Diabetes 2012; 61: 208-216.
    • (2012) Diabetes , vol.61 , pp. 208-216
    • Gil, N.1    Goldberg, R.2    Neuman, T.3
  • 30
    • 79958065612 scopus 로고    scopus 로고
    • Uninephrectomy of diabetic OVE26 mice greatly accelerates albuminuria, fibrosis, inflammatory cell infiltration and changes in gene expression
    • Zheng S, Huang Y, Yang L et al. Uninephrectomy of diabetic OVE26 mice greatly accelerates albuminuria, fibrosis, inflammatory cell infiltration and changes in gene expression. Nephron Exp Nephrol 2011; 119: e21-e32.
    • (2011) Nephron Exp Nephrol , vol.119
    • Zheng, S.1    Huang, Y.2    Yang, L.3
  • 31
    • 79951639177 scopus 로고    scopus 로고
    • Nebivolol attenuates redoxsensitive glomerular and tubular mediated proteinuria in obese rats
    • Habibi J, Hayden MR, Sowers JR et al. Nebivolol attenuates redoxsensitive glomerular and tubular mediated proteinuria in obese rats. Endocrinology 2011; 152: 659-668.
    • (2011) Endocrinology , vol.152 , pp. 659-668
    • Habibi, J.1    Hayden, M.R.2    Sowers, J.R.3
  • 32
    • 35848931880 scopus 로고    scopus 로고
    • Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes mellitus: Role in the development of diabetic glomerular disease
    • DOI 10.1007/s00125-007-0821-y
    • Menini S, Iacobini C, Oddi G et al. Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes mellitus: role in the development of diabetic glomerular disease. Diabetologia 2007; 50: 2591-2599. (Pubitemid 350060642)
    • (2007) Diabetologia , vol.50 , Issue.12 , pp. 2591-2599
    • Menini, S.1    Iacobini, C.2    Oddi, G.3    Ricci, C.4    Simonelli, P.5    Fallucca, S.6    Grattarola, M.7    Pugliese, F.8    Pesce, C.9    Pugliese, G.10
  • 33
    • 38949151661 scopus 로고    scopus 로고
    • Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy
    • DOI 10.2174/157339908783502370
    • Ziyadeh FN, Wolf G. Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy. Curr Diabetes Rev 2008; 4: 39-45. (Pubitemid 351210971)
    • (2008) Current Diabetes Reviews , vol.4 , Issue.1 , pp. 39-45
    • Ziyadeh, F.N.1    Wolf, G.2
  • 34
    • 60549095158 scopus 로고    scopus 로고
    • Angiotensin-(1-7) activates growth-stimulatory pathways in human mesangial cells
    • Zimpelmann J, Burns KD. Angiotensin-(1-7) activates growth-stimulatory pathways in human mesangial cells. Am J Physiol Renal Physiol 2009; 296: F337-F346.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Zimpelmann, J.1    Burns, K.D.2
  • 35
    • 79958143772 scopus 로고    scopus 로고
    • Attenuating effect of angiotensin-(1-7) on angiotensin II-mediated NAD(P)H oxidase activation in type 2 diabetic nephropathy of KK-A(y)/Ta mice
    • Moon JY, Tanimoto M, Gohda T et al. Attenuating effect of angiotensin-(1-7) on angiotensin II-mediated NAD(P)H oxidase activation in type 2 diabetic nephropathy of KK-A(y)/Ta mice. Am J Physiol Renal Physiol 2011; 300: F1271-F1282.
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Moon, J.Y.1    Tanimoto, M.2    Gohda, T.3
  • 37
    • 77952737389 scopus 로고    scopus 로고
    • Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease
    • Dilauro M, Zimpelmann J, Robertson SJ et al. Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease. Am J Physiol Renal Physiol 2010; 298: F1523-F1532.
    • (2010) Am J Physiol Renal Physiol , vol.298
    • Dilauro, M.1    Zimpelmann, J.2    Robertson, S.J.3
  • 39
    • 34447639739 scopus 로고    scopus 로고
    • Temporal-spatial expression of ANG-(1-7) and angiotensin-converting enzyme 2 in the kidney of normal and hypertensive pregnant rats
    • Joyner J, Neves LAA, Granger JP et al. Temporal-spatial expression of ANG-(1-7) and angiotensin-converting enzyme 2 in the kidney of normal and hypertensive pregnant rats. Am J Physiol Regul Integr Comp Physiol 2007; 293: 169-177.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293 , pp. 169-177
    • Joyner, J.1    Neves, L.A.A.2    Granger, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.