-
1
-
-
0034721906
-
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril insensitive carboxypeptidase
-
Tipnis SR, Hooper NM, Hyde R, Karran E, Christie G, Turner AJ. (2000) A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril insensitive carboxypeptidase. J. Biol. Chem. 275:33238-33243.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 33238-33243
-
-
Tipnis, S.R.1
Hooper, N.M.2
Hyde, R.3
Karran, E.4
Christie, G.5
Turner, A.J.6
-
2
-
-
0038053724
-
A novel angiotensinconverting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
-
Donoghue M, et al. (2000) A novel angiotensinconverting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ. Res. 87:E1-E9.
-
(2000)
Circ. Res
, vol.87
-
-
Donoghue, M.1
-
3
-
-
18544378161
-
Hydrolysis of biological peptides by human angiotensin-converting enzyme- related carboxypeptidase
-
Vickers C, et al. (2002) Hydrolysis of biological peptides by human angiotensin-converting enzyme- related carboxypeptidase. J. Biol. Chem. 277:14838-14843.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 14838-14843
-
-
Vickers, C.1
-
4
-
-
33744731510
-
Loss of angiotensinconverting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis
-
Oudit GY, et al. (2006) Loss of angiotensinconverting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis. Am. J. Pathol. 168:1808-1820.
-
(2006)
Am. J. Pathol
, vol.168
, pp. 1808-1820
-
-
Oudit, G.Y.1
-
5
-
-
0037142101
-
Angiotensin-converting enzyme 2 is an essential regulator of heart function
-
Crackower MA, et al. (2002) Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 417:822-828.
-
(2002)
Nature
, vol.417
, pp. 822-828
-
-
Crackower, M.A.1
-
6
-
-
33645834948
-
Deletion of angiotensinconverting enzyme 2 accelerates pressure overload- induced cardiac dysfunction by increasing local angiotensin II
-
Yamamoto K, et al. (2006) Deletion of angiotensinconverting enzyme 2 accelerates pressure overload- induced cardiac dysfunction by increasing local angiotensin II. Hypertension 47:718-726.
-
(2006)
Hypertension
, vol.47
, pp. 718-726
-
-
Yamamoto, K.1
-
7
-
-
33749437743
-
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR
-
Diez-Freire C, et al. (2006) ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR. Physiol. Genom. 27:12-19.
-
(2006)
Physiol. Genom
, vol.27
, pp. 12-19
-
-
Diez-Freire, C.1
-
8
-
-
46249090611
-
Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis
-
Dong B, et al. (2008) Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 28:1270-6.
-
(2008)
Arterioscler. Thromb. Vasc. Biol
, vol.28
, pp. 1270-1276
-
-
Dong, B.1
-
9
-
-
55949126600
-
Transgenic angiotensinconverting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function
-
Rentzsch B, et al. (2008) Transgenic angiotensinconverting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function. Hypertension 52:967-973.
-
(2008)
Hypertension
, vol.52
, pp. 967-973
-
-
Rentzsch, B.1
-
10
-
-
0032543872
-
Pathogenesis, prevention, and treatment of diabetic nephropathy
-
Cooper ME. (1998) Pathogenesis, prevention, and treatment of diabetic nephropathy. Lancet 352:213-219.
-
(1998)
Lancet
, vol.352
, pp. 213-219
-
-
Cooper, M.E.1
-
11
-
-
0035138961
-
Therapeutic benefits of ACE inhibitors and other antihypertensive drugs in patients with type 2 diabetes
-
Parving HH, Rossing P. (2001) Therapeutic benefits of ACE inhibitors and other antihypertensive drugs in patients with type 2 diabetes. Diabetes Care 24:177-180.
-
(2001)
Diabetes Care
, vol.24
, pp. 177-180
-
-
Parving, H.H.1
Rossing, P.2
-
12
-
-
42449140640
-
ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetes
-
Tikellis C, et al. (2008) ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetes. Diabetes 57:1018-1025.
-
(2008)
Diabetes
, vol.57
, pp. 1018-1025
-
-
Tikellis, C.1
-
13
-
-
33646579401
-
The therapeutic potential of angiotensin-(1-7) as a novel reninangiotensin system mediator. Mini
-
Simões e Silva AC, Pinheiro SV, Pereira RM, Ferreira AJ, Santos RA. (2006) The therapeutic potential of angiotensin-(1-7) as a novel reninangiotensin system mediator. Mini Rev. Med. Chem. 6:603-609.
-
(2006)
Rev. Med. Chem
, vol.6
, pp. 603-609
-
-
Simões e Silva, A.C.1
Pinheiro, S.V.2
Pereira, R.M.3
Ferreira, A.J.4
Santos, R.A.5
-
15
-
-
28144445338
-
Advances in biochemical and functional roles of angiotensin- converting enzyme 2 and angiotensin- (1-7) in regulation of cardiovascular function
-
Ferrario CM, Trask AJ, Jessup JA. (2005) Advances in biochemical and functional roles of angiotensin- converting enzyme 2 and angiotensin- (1-7) in regulation of cardiovascular function. Am. J. Physiol. 289:H2281-H2290.
-
(2005)
Am. J. Physiol
, vol.289
-
-
Ferrario, C.M.1
Trask, A.J.2
Jessup, J.A.3
-
16
-
-
0023258423
-
Angiotensin receptor subtypes of the kidney cortex
-
Douglas JG. (1987) Angiotensin receptor subtypes of the kidney cortex. Am. J. Physiol. 253:F1-F7.
-
(1987)
Am. J. Physiol
, vol.253
-
-
Douglas, J.G.1
-
18
-
-
57049086924
-
Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease
-
Reich HN, Oudit GY, Penninger JM, Scholey JW, Herzenberg AM. (2008) Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease. Kidney Int. 74:1610-1616.
-
(2008)
Kidney Int
, vol.74
, pp. 1610-1616
-
-
Reich, H.N.1
Oudit, G.Y.2
Penninger, J.M.3
Scholey, J.W.4
Herzenberg, A.M.5
-
19
-
-
34548153521
-
ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice
-
Soler MJ, Wysocki J, Ye M, Lloveras J, Kanwar Y, Batlle D. (2007) ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice. Kidney Int. 72:614-623.
-
(2007)
Kidney Int
, vol.72
, pp. 614-623
-
-
Soler, M.J.1
Wysocki, J.2
Ye, M.3
Lloveras, J.4
Kanwar, Y.5
Batlle, D.6
-
20
-
-
34548295365
-
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
-
Wong DW, Oudit GY, Reich H, et al. (2007) Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. Am. J. Pathol. 171:438-451.
-
(2007)
Am. J. Pathol
, vol.171
, pp. 438-451
-
-
Wong, D.W.1
Oudit, G.Y.2
Reich, H.3
-
21
-
-
33750722109
-
Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: Implications for albuminuria in diabetes
-
Ye M, Wysocki J, William J, Soler MJ, Cokic I, Batlle D. (2006) Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: implications for albuminuria in diabetes. J. Am. Soc. Nephrol. 17:3067-375.
-
(2006)
J. Am. Soc. Nephrol
, vol.17
, pp. 3067-3375
-
-
Ye, M.1
Wysocki, J.2
William, J.3
Soler, M.J.4
Cokic, I.5
Batlle, D.6
-
22
-
-
77449160523
-
Human recombinant ACE2 reduces the progression of diabetic nephropathy
-
Oudit GY, et al. Human recombinant ACE2 reduces the progression of diabetic nephropathy. Diabetes 59:529-538.
-
Diabetes
, vol.59
, pp. 529-538
-
-
Oudit, G.Y.1
-
23
-
-
60049086525
-
Rosiglitazone protects diabetic rats against kidney disease through the suppression of renal moncyte chemoattractant protein-1 expression
-
Zheng M, et al. (2009) Rosiglitazone protects diabetic rats against kidney disease through the suppression of renal moncyte chemoattractant protein-1 expression. J. Diabetes Complications 23:124-129.
-
(2009)
J. Diabetes Complications
, vol.23
, pp. 124-129
-
-
Zheng, M.1
-
24
-
-
33645702760
-
Suppression of transforming growth factor-beta1 gene expression by Danggui buxue tang, a traditional Chinese herbal preparation, in retarding the progress of renal damage in streptozotocin- induced diabetic rats
-
Zhang YW, Xie D, Xia B, Zhen RT, Liu IM, Cheng JT. (2006) Suppression of transforming growth factor-beta1 gene expression by Danggui buxue tang, a traditional Chinese herbal preparation, in retarding the progress of renal damage in streptozotocin- induced diabetic rats. Horm Metab Res 38:82-88.
-
(2006)
Horm Metab Res
, vol.38
, pp. 82-88
-
-
Zhang, Y.W.1
Xie, D.2
Xia, B.3
Zhen, R.T.4
Liu, I.M.5
Cheng, J.T.6
-
25
-
-
33747052918
-
ACE and ACE2 activity in diabetic mice
-
Wysocki J, et al. (2006) ACE and ACE2 activity in diabetic mice. Diabetes 55:2132-2139.
-
(2006)
Diabetes
, vol.55
, pp. 2132-2139
-
-
Wysocki, J.1
-
26
-
-
0033517863
-
Angiotensin II activates collagen type I gene in the renal vasculature of transgenic mice during inhibition of nitric oxide synthesis: Evidence for an endothelinmediated mechanism
-
Boffa JJ, Tharaux PL, Placier S, Ardaillou R, Dussaule JC, Chatziantoniou C. (1999) Angiotensin II activates collagen type I gene in the renal vasculature of transgenic mice during inhibition of nitric oxide synthesis: evidence for an endothelinmediated mechanism. Circulation 100:1901-1908.
-
(1999)
Circulation
, vol.100
, pp. 1901-1908
-
-
Boffa, J.J.1
Tharaux, P.L.2
Placier, S.3
Ardaillou, R.4
Dussaule, J.C.5
Chatziantoniou, C.6
-
27
-
-
34248216953
-
Rodent models of streptozotocin-induced diabetic nephropathy
-
Tesch GH, Allen TJ. (2007) Rodent models of streptozotocin-induced diabetic nephropathy. Nephrology (Carlton) 12:261-266.
-
(2007)
Nephrology (Carlton)
, vol.12
, pp. 261-266
-
-
Tesch, G.H.1
Allen, T.J.2
-
28
-
-
0034021275
-
Effects of endothelin or angiotensin II receptor blockade on diabetes in the transgenic (mRen-2)27 rat
-
Kelly DJ, Skinner SL, Gilbert RE, Cox AJ, Cooper ME, Wilkinson-Berka JL. (2000) Effects of endothelin or angiotensin II receptor blockade on diabetes in the transgenic (mRen-2)27 rat. Kidney Int. 57:1882-1894.
-
(2000)
Kidney Int
, vol.57
, pp. 1882-1894
-
-
Kelly, D.J.1
Skinner, S.L.2
Gilbert, R.E.3
Cox, A.J.4
Cooper, M.E.5
Wilkinson-Berka, J.L.6
-
29
-
-
0027525040
-
Renal renin-angiotensin system in diabetes: Functional, immunohistochemical, and molecular biological correlations
-
Anderson S, Jung FF, Ingelfinger JR. (1993) Renal renin-angiotensin system in diabetes: functional, immunohistochemical, and molecular biological correlations. Am. J. Physiol. 265:F477-F486.
-
(1993)
Am. J. Physiol
, vol.265
-
-
Anderson, S.1
Jung, F.F.2
Ingelfinger, J.R.3
-
30
-
-
34249900226
-
Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice
-
Oudit GY, et al. (2007) Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovasc. Res. 75:29-39.
-
(2007)
Cardiovasc. Res
, vol.75
, pp. 29-39
-
-
Oudit, G.Y.1
-
32
-
-
0037341501
-
Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy
-
Tikellis C, et al. (2003) Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy. Hypertension 41:392-397.
-
(2003)
Hypertension
, vol.41
, pp. 392-397
-
-
Tikellis, C.1
-
33
-
-
38949151661
-
Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy
-
Ziyadeh FN, Wolf G. (2008) Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy. Curr. Diabetes Rev. 4:39-45.
-
(2008)
Curr. Diabetes Rev
, vol.4
, pp. 39-45
-
-
Ziyadeh, F.N.1
Wolf, G.2
-
34
-
-
33845262861
-
Renal injury due to renin-angiotensin- aldosterone system activation of the transforming growth factor-beta pathway
-
Wolf G. (2006) Renal injury due to renin-angiotensin- aldosterone system activation of the transforming growth factor-beta pathway. Kidney Int. 70:1914-1919.
-
(2006)
Kidney Int
, vol.70
, pp. 1914-1919
-
-
Wolf, G.1
-
35
-
-
0347511753
-
Mediators of diabetic renal disease: The case for tgf-Beta as the major mediator
-
Ziyadeh FN. (2004) Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator. J. Am. Soc. Nephrol. 15 Suppl 1:S55-S57.
-
(2004)
J. Am. Soc. Nephrol
, vol.15
, Issue.SUPPL 1
-
-
Ziyadeh, F.N.1
-
36
-
-
37549035027
-
Diabetic nephropathy: Mechanisms of renal disease progression
-
Kanwar YS, et al. (2008) Diabetic nephropathy: mechanisms of renal disease progression. Exp Biol Med (Maywood) 233:4-11.
-
(2008)
Exp Biol Med (Maywood)
, vol.233
, pp. 4-11
-
-
Kanwar, Y.S.1
-
37
-
-
27444433984
-
Angiotensin-converting enzyme 2 (ACE2) and ACE activities display tissue-specific sensitivity to undernutritionprogrammed hypertension in the adult rat
-
Riviere G, et al. (2005) Angiotensin-converting enzyme 2 (ACE2) and ACE activities display tissue-specific sensitivity to undernutritionprogrammed hypertension in the adult rat. Hypertension 46:1169-1174.
-
(2005)
Hypertension
, vol.46
, pp. 1169-1174
-
-
Riviere, G.1
-
38
-
-
0037365404
-
Treatment of diabetic nephropathy with angiotensin II receptor antagonist
-
Lewis EJ, Lewis JB. (2003) Treatment of diabetic nephropathy with angiotensin II receptor antagonist. Clin. Exp. Nephrol. 7:1-8.
-
(2003)
Clin. Exp. Nephrol
, vol.7
, pp. 1-8
-
-
Lewis, E.J.1
Lewis, J.B.2
-
39
-
-
64849108788
-
Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2
-
Masson R, et al. (2009) Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2. Hypertension 53:694-700.
-
(2009)
Hypertension
, vol.53
, pp. 694-700
-
-
Masson, R.1
-
40
-
-
58149243501
-
Chronic angiotensin (1-7) injection accelerates STZ-induced diabetic renal injury
-
Shao Y, He M, Zhou L, Yao T, Huang Y, Lu LM. (2008) Chronic angiotensin (1-7) injection accelerates STZ-induced diabetic renal injury. Acta. Pharmacol. Sin. 29:829-37.
-
(2008)
Acta. Pharmacol. Sin
, vol.29
, pp. 829-837
-
-
Shao, Y.1
He, M.2
Zhou, L.3
Yao, T.4
Huang, Y.5
Lu, L.M.6
-
41
-
-
2342472108
-
Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: A renoprotective combination?
-
Ye M, Wysocki J, Naaz P, Salabat MR, LaPointe MS, Batlle D. (2004) Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination? Hypertension 43:1120-25.
-
(2004)
Hypertension
, vol.43
, pp. 1120-1125
-
-
Ye, M.1
Wysocki, J.2
Naaz, P.3
Salabat, M.R.4
Lapointe, M.S.5
Batlle, D.6
-
42
-
-
4444345300
-
Combined therapy of cilazapril and losartan has no additive effects in ameliorating adriamycin-induced glomerulopathy
-
Kim HJ, et al. (2004) Combined therapy of cilazapril and losartan has no additive effects in ameliorating adriamycin-induced glomerulopathy. Nephron 97:58-65.
-
(2004)
Nephron
, vol.97
, pp. 58-65
-
-
Kim, H.J.1
|